Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External M...
Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External Model Evaluation and Simulations
About this item
Full title
Author / Creator
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
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Scope and Contents
Contents
Objectives
A developed population pharmacokinetic model of the humanized monoclonal antibody (mAb) matuzumab was evaluated by external evaluation. Based on the estimates of the final model, simulations of different dosing regimens and the covariate effect were performed.
Methods
The development dataset included 90 patients, and the evaluat...
Alternative Titles
Full title
Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External Model Evaluation and Simulations
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Record Identifier
TN_cdi_proquest_journals_222744087
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222744087
Other Identifiers
ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.2165/11313400-000000000-00000
