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ArticlesPeer ReviewedFull Text
Androgen receptor-binding sites are highly mutated in prostate cancer
Author / Creator:Morova, Tunç ; McNeill, Daniel R. ; Lallous, Nada ; Gönen, Mehmet ; Dalal, Kush ; Wilson, David M. ; Gürsoy, Attila ; Keskin, Özlem ; Lack, Nathan A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.832-10, Article 832
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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models
Author / Creator:Nappi, Lucia ; Aguda, Adeleke H ; Nakouzi, Nader Al ; Lelj-Garolla, Barbara ; Beraldi, Eliana ; Lallous, Nada ; Thi, Marisa ; Moore, Susan ; Fazli, Ladan ; Battsogt, Dulguun ; Stief, Sophie ; Ban, Fuqiang ; Nguyen, Nham T ; Saxena, Neetu ; Dueva, Evgenia ; Zhang, Fan ; Yamazaki, Takeshi ; Zoubeidi, Amina ; Cherkasov, Artem ; Brayer, Gary D ; Gleave, Martin
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-02, Vol.130 (2), p.699-714
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Characterization of novel small molecule inhibitors of estrogen receptor-activation function 2 (ER-AF2)
Author / Creator:Foo, Jane ; Gentile, Francesco ; Massah, Shabnam ; Morin, Helene ; Singh, Kriti ; Lee, Joseph ; Smith, Jason ; Ban, Fuqiang ; LeBlanc, Eric ; Young, Robert ; Strynadka, Natalie ; Lallous, Nada ; Cherkasov, Artem
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2024-11, Vol.26 (1), p.168-16, Article 168
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Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer
Author / Creator:Carabet, Lavinia A ; Leblanc, Eric ; Lallous, Nada ; Morin, Helene ; Ghaidi, Fariba ; Lee, Joseph ; Rennie, Paul S ; Cherkasov, Artem
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-02, Vol.24 (4), p.763
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Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
Author / Creator:Lallous, Nada ; Dalal, Kush ; Cherkasov, Artem ; Rennie, Paul S
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2013-06, Vol.14 (6), p.12496-12519
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Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer
Author / Creator:Al-Nakouzi, Nader ; Wang, Chris Kedong ; Oo, Htoo Zarni ; Nelepcu, Irina ; Lallous, Nada ; Spliid, Charlotte B. ; Khazamipour, Nastaran ; Lo, Joey ; Truong, Sarah ; Collins, Colin ; Hui, Desmond ; Esfandnia, Shaghayegh ; Adomat, Hans ; Clausen, Thomas Mandel ; Gustavsson, Tobias ; Choudhary, Swati ; Dagil, Robert ; Corey, Eva ; Wang, Yuzhuo ; Chauchereau, Anne ; Fazli, Ladan ; Esko, Jeffrey D. ; Salanti, Ali ; Nelson, Peter S. ; Gleave, Martin E. ; Daugaard, Mads
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4760-4760, Article 4760
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Developing novel Lin28 inhibitors by computer aided drug design
Author / Creator:Matias-Barrios, Victor M. ; Radaeva, Mariia ; Rosellinny, Graciella ; Jia, Qiongqiong ; Xie, Ning ; Villanueva, Monica ; Ibrahim, Hanadi ; Smith, Jason ; Gleave, Martin ; Lallous, Nada ; Straus, Suzana K. ; Cherkasov, Artem ; Dong, Xuesen
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2025-01, Vol.11 (1), p.5-11, Article 5
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The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers
Author / Creator:Lallous, Nada ; Legrand, Pierre ; McEwen, Alastair G ; Ramón-Maiques, Santiago ; Samama, Jean-Pierre ; Birck, Catherine
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-11, Vol.6 (11), p.e27599-e27599
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Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors
Author / Creator:Radaeva, Mariia ; Li, Huifang ; LeBlanc, Eric ; Dalal, Kush ; Ban, Fuqiang ; Ciesielski, Fabrice ; Chow, Bonny ; Morin, Helene ; Awrey, Shannon ; Singh, Kriti ; Rennie, Paul S ; Lallous, Nada ; Cherkasov, Artem
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-09, Vol.11 (18), p.2785
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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies
Author / Creator:Snow, Oliver ; Lallous, Nada ; Ester, Martin ; Cherkasov, Artem
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-08, Vol.21 (16), p.5847
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Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients
Author / Creator:Lallous, Nada ; Volik, Stanislav V ; Awrey, Shannon ; Leblanc, Eric ; Tse, Ronnie ; Murillo, Josef ; Singh, Kriti ; Azad, Arun A ; Wyatt, Alexander W ; LeBihan, Stephane ; Chi, Kim N ; Gleave, Martin E ; Rennie, Paul S ; Collins, Colin C ; Cherkasov, Artem
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2016-01, Vol.17 (1), p.10-10, Article 10
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Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor
Author / Creator:Radaeva, Mariia ; Ban, Fuqiang ; Zhang, Fan ; LeBlanc, Eric ; Lallous, Nada ; Rennie, Paul S ; Gleave, Martin E ; Cherkasov, Artem
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-03, Vol.22 (5), p.2493
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Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer
Author / Creator:Ton, Anh-Tien ; Singh, Kriti ; Morin, Hélène ; Ban, Fuqiang ; Leblanc, Eric ; Lee, Joseph ; Lallous, Nada ; Cherkasov, Artem
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-11, Vol.21 (21), p.8277
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Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness
Author / Creator:Radaeva, Mariia ; Ho, Chia-Hao ; Xie, Ning ; Zhang, Sijie ; Lee, Joseph ; Liu, Liangliang ; Lallous, Nada ; Cherkasov, Artem ; Dong, Xuesen
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2022-11, Vol.14 (22), p.5687
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Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer
Author / Creator:Ton, Anh-Tien ; Foo, Jane ; Singh, Kriti ; Lee, Joseph ; Kalyta, Anastasia ; Morin, Helene ; Perez, Carl ; Ban, Fuqiang ; Leblanc, Eric ; Lallous, Nada ; Cherkasov, Artem
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-02, Vol.23 (5), p.2588
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Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy
Author / Creator:Matias-Barrios, Victor M. ; Radaeva, Mariia ; Ho, Chia-Hao ; Lee, Joseph ; Adomat, Hans ; Lallous, Nada ; Cherkasov, Artem ; Dong, Xuesen
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-07, Vol.13 (15), p.3675
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Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients
Author / Creator:Lallous, Nada ; Snow, Oliver ; Sanchez, Christophe ; Parra Nuñez, Ana Karla ; Sun, Bei ; Hussain, Ahmed ; Lee, Joseph ; Morin, Helene ; Leblanc, Eric ; Gleave, Martin E. ; Cherkasov, Artem
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-06, Vol.13 (12), p.2939
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Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer
Author / Creator:Ban, Fuqiang ; Leblanc, Eric ; Cavga, Ayse Derya ; Huang, Chia-Chi Flora ; Flory, Mark R ; Zhang, Fan ; Chang, Matthew E K ; Morin, Hélène ; Lallous, Nada ; Singh, Kriti ; Gleave, Martin E ; Mohammed, Hisham ; Rennie, Paul S ; Lack, Nathan A ; Cherkasov, Artem
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-07, Vol.13 (14), p.3488
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Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers
Author / Creator:Singh, Kriti ; Munuganti, Ravi S N ; Lallous, Nada ; Dalal, Kush ; Yoon, Ji Soo ; Sharma, Aishwariya ; Yamazaki, Takeshi ; Cherkasov, Artem ; Rennie, Paul S
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-02, Vol.19 (2), p.579
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In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α
Author / Creator:Singh, Kriti ; Munuganti, Ravi Shashi Nayana ; Leblanc, Eric ; Lin, Yu Lun ; Leung, Euphemia ; Lallous, Nada ; Butler, Miriam ; Cherkasov, Artem ; Rennie, Paul S
Publisher:England: BioMed Central
Journal title:Breast cancer research : BCR, 2015-02, Vol.17 (1), p.27-27, Article 27
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Showing 1 to 20 of 24 results

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Androgen receptor-binding sites are highly mutated in prostate cancer

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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

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Characterization of novel small molecule inhibitors of estrogen receptor-activation function 2 (ER-AF2)

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Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer

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Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer

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Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer

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Developing novel Lin28 inhibitors by computer aided drug design

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The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers

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Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors

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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies

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Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients

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Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor

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Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer

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Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness

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Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer

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Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy

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Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients

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Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer

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Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers

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In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α

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