Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
About this item
Full title
Author / Creator
Kopetz, Scott , Grothey, Axel , Yaeger, Rona , Van Cutsem, Eric , Desai, Jayesh , Yoshino, Takayuki , Wasan, Harpreet , Ciardiello, Fortunato , Loupakis, Fotios , Hong, Yong Sang , Steeghs, Neeltje , Guren, Tormod K , Arkenau, Hendrik-Tobias , Garcia-Alfonso, Pilar , Pfeiffer, Per , Orlov, Sergey , Lonardi, Sara , Elez, Elena , Kim, Tae-Won , Schellens, Jan H.M , Guo, Christina , Krishnan, Asha , Dekervel, Jeroen , Morris, Van , Calvo Ferrandiz, Aitana , Tarpgaard, L.S , Braun, Michael , Gollerkeri, Ashwin , Keir, Christopher , Maharry, Kati , Pickard, Michael , Christy-Bittel, Janna , Anderson, Lisa , Sandor, Victor and Tabernero, Josep
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Colorectal cancers with
BRAF
mutations have an aggressive natural history and are often resistant to therapy. A treatment regimen that combined BRAF inhibition, MET inhibition, and blocking of EGFR signaling resulted in a response rate of 26% and a median overall survival of 9 months.
Alternative Titles
Full title
Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
Authors, Artists and Contributors
Author / Creator
Grothey, Axel
Yaeger, Rona
Van Cutsem, Eric
Desai, Jayesh
Yoshino, Takayuki
Wasan, Harpreet
Ciardiello, Fortunato
Loupakis, Fotios
Hong, Yong Sang
Steeghs, Neeltje
Guren, Tormod K
Arkenau, Hendrik-Tobias
Garcia-Alfonso, Pilar
Pfeiffer, Per
Orlov, Sergey
Lonardi, Sara
Elez, Elena
Kim, Tae-Won
Schellens, Jan H.M
Guo, Christina
Krishnan, Asha
Dekervel, Jeroen
Morris, Van
Calvo Ferrandiz, Aitana
Tarpgaard, L.S
Braun, Michael
Gollerkeri, Ashwin
Keir, Christopher
Maharry, Kati
Pickard, Michael
Christy-Bittel, Janna
Anderson, Lisa
Sandor, Victor
Tabernero, Josep
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2299449148
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299449148
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1908075
