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ArticlesPeer ReviewedFull Text
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
Author / Creator:Schläger, Christian ; Körner, Henrike ; Krueger, Martin ; Vidoli, Stefano ; Haberl, Michael ; Mielke, Dorothee ; Brylla, Elke ; Issekutz, Thomas ; Cabañas, Carlos ; Nelson, Peter J. ; Ziemssen, Tjalf ; Rohde, Veit ; Bechmann, Ingo ; Lodygin, Dmitri ; Odoardi, Francesca ; Flügel, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7590), p.349-353
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Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity
Author / Creator:Wang, Mitchell S. ; Hu, Yuesong ; Sanchez, Elisa E. ; Xie, Xihe ; Roy, Nathan H. ; de Jesus, Miguel ; Winer, Benjamin Y. ; Zale, Elizabeth A. ; Jin, Weiyang ; Sachar, Chirag ; Lee, Joanne H. ; Hong, Yeonsun ; Kim, Minsoo ; Kam, Lance C. ; Salaita, Khalid ; Huse, Morgan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3222-15, Article 3222
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JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation
Author / Creator:Edelmann, Bärbel ; Gupta, Nibedita ; Schnoeder, Tina M. ; Oelschlegel, Anja M. ; Shahzad, Khurrum ; Goldschmidt, Jürgen ; Philipsen, Lars ; Weinert, Soenke ; Ghosh, Aniket ; Saalfeld, Felix C. ; Nimmagadda, Subbaiah Chary ; Müller, Peter ; Braun-Dullaeus, Rüdiger ; Mohr, Juliane ; Wolleschak, Denise ; Kliche, Stefanie ; Amthauer, Holger ; Heidel, Florian H. ; Schraven, Burkhart ; Isermann, Berend ; Müller, Andreas J. ; Fischer, Thomas
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4359-4371
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The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss
Author / Creator:Eskan, Mehmet A ; Jotwani, Ravi ; Abe, Toshiharu ; Chmelar, Jindrich ; Lim, Jong-Hyung ; Liang, Shuang ; Ciero, Paul A ; Krauss, Jennifer L ; Li, Fenge ; Rauner, Martina ; Hofbauer, Lorenz C ; Choi, Eun Young ; Chung, Kyoung-Jin ; Hashim, Ahmed ; Curtis, Michael A ; Chavakis, Triantafyllos ; Hajishengallis, George
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2012-05, Vol.13 (5), p.465-473
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Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
Author / Creator:Hons, Miroslav ; Kopf, Aglaja ; Hauschild, Robert ; Leithner, Alexander ; Gaertner, Florian ; Abe, Jun ; Renkawitz, Jörg ; Stein, Jens V. ; Sixt, Michael
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-06, Vol.19 (6), p.606-616
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CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover
Author / Creator:Martinez, Amera L. ; Shannon, Michael J. ; Sloan, Tyler ; Mace, Emily M.
Publisher:United States: American Society for Cell Biology
Journal title:Molecular biology of the cell, 2024-05, Vol.35 (5), p.ar64
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The insider's guide to leukocyte integrin signalling and function
Author / Creator:Hogg, Nancy ; Patzak, Irene ; Willenbrock, Frances
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2011-06, Vol.11 (6), p.416-426
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Innate Response Activator B Cells Protect Against Microbial Sepsis
Author / Creator:Rauch, Philipp J. ; Chudnovskiy, Aleksey ; Robbins, Clinton S. ; Weber, Georg F. ; Etzrodt, Martin ; Hilgendorf, Ingo ; Tiglao, Elizabeth ; Figueiredo, Jose-Luiz ; Iwamoto, Yoshiko ; Theurl, Igor ; Gorbatov, Rostic ; Waring, Michael T. ; Chicoine, Adam T. ; Mouded, Majd ; Pittet, Mikael J. ; Nahrendorf, Matthias ; Weissleder, Ralph ; Swirski, Filip K.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-02, Vol.335 (6068), p.597-601
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ArticlesPeer ReviewedFull Text
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
Author / Creator:Nordenfelt, Pontus ; Moore, Travis I. ; Mehta, Shalin B. ; Kalappurakkal, Joseph Mathew ; Swaminathan, Vinay ; Koga, Nobuyasu ; Lambert, Talley J. ; Baker, David ; Waters, Jennifer C. ; Oldenbourg, Rudolf ; Tani, Tomomi ; Mayor, Satyajit ; Waterman, Clare M. ; Springer, Timothy A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.2047-16, Article 2047
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ArticlesPeer ReviewedFull Text
Integrin cross-talk modulates stiffness-independent motility of CD4+ T lymphocytes
Author / Creator:Kim, Sarah Hyun Ji ; Hammer, Daniel A.
Publisher:United States: The American Society for Cell Biology
Journal title:Molecular biology of the cell, 2021-08, Vol.32 (18), p.1749-1757
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Recruitment of calcineurin to the TCR positively regulates T cell activation
Author / Creator:Dutta, Debjani ; Barr, Valarie A ; Akpan, Itoro ; Mittelstadt, Paul R ; Singha, Laishram I ; Samelson, Lawrence E ; Ashwell, Jonathan D
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2017-02, Vol.18 (2), p.196-204
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ArticlesPeer ReviewedFull Text
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A
Author / Creator:Nielsen, Natasja ; Ødum, Niels ; Ursø, Birgitte ; Lanier, Lewis L ; Spee, Pieter
Publisher:United States: Public Library of Science (PLoS)
Journal title:PloS one, 2012, Vol.7 (2), p.e31959-e31959
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ArticlesPeer ReviewedFull Text
The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling
Author / Creator:Kondo, Naoyuki ; Mimori-Kiyosue, Yuko ; Tokuhiro, Keizo ; Pezzotti, Giuseppe ; Kinashi, Tatsuo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1343-14, Article 1343
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ArticlesPeer ReviewedFull Text
Foxp3⁺ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
Author / Creator:Onishi, Yasushi ; Fehervari, Zoltan ; Yamaguchi, Tomoyuki ; Sakaguchi, Shimon
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (29), p.10113-10118
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ArticlesPeer ReviewedFull Text
LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro
Author / Creator:Jansen, Robin ; Pawlitzki, Marc ; Gliem, Michael ; Meuth, Sven G. ; Schreiber, Stefanie ; Görtler, Michael-W. ; Neumann, Jens
Publisher:United States: Public Library of Science
Journal title:PloS one, 2025-01, Vol.20 (1), p.e0314020
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ArticlesPeer ReviewedFull Text
Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy
Author / Creator:Brown, Alice C. N. ; Oddos, Stephane ; Dobbie, Ian M. ; Alakoskela, Juha-Matti ; Parton, Richard M. ; Eissmann, Philipp ; Neil, Mark A. A. ; Dunsby, Christopher ; French, Paul M. W. ; Davis, Ilan ; Davis, Daniel M.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2011-09, Vol.9 (9), p.e1001152-e1001152
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ArticlesPeer ReviewedFull Text
Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson’s Disease
Author / Creator:Liu, Zhan ; Huang, Yan ; Cao, Bei-Bei ; Qiu, Yi-Hua ; Peng, Yu-Ping
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2017-12, Vol.54 (10), p.7762-7776
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‘Slings’ enable neutrophil rolling at high shear
Author / Creator:Sundd, Prithu ; Gutierrez, Edgar ; Koltsova, Ekaterina K. ; Kuwano, Yoshihiro ; Fukuda, Satoru ; Pospieszalska, Maria K. ; Groisman, Alex ; Ley, Klaus
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-08, Vol.488 (7411), p.399-403
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ArticlesPeer ReviewedFull Text
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions
Author / Creator:Zahr, Alisar ; Alcaide, Pilar ; Yang, Jinling ; Jones, Alexander ; Gregory, Meredith ; dela Paz, Nathaniel G. ; Patel-Hett, Sunita ; Nevers, Tania ; Koirala, Adarsha ; Luscinskas, Francis W. ; Saint-Geniez, Magali ; Ksander, Bruce ; D’Amore, Patricia A. ; Argüeso, Pablo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-02, Vol.7 (1), p.10363-10363, Article 10363
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Viral modulation of type II interferon increases T cell adhesion and virus spread
Author / Creator:Jacobsen, Carina ; Plückebaum, Nina ; Ssebyatika, George ; Beyer, Sarah ; Mendes-Monteiro, Lucas ; Wang, Jiayi ; Kropp, Kai A. ; González-Motos, Víctor ; Steinbrück, Lars ; Ritter, Birgit ; Rodríguez-González, Claudio ; Böning, Heike ; Nikolouli, Eirini ; Kinchington, Paul R. ; Lachmann, Nico ; Depledge, Daniel P. ; Krey, Thomas ; Viejo-Borbolla, Abel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.5318-18, Article 5318
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Showing 1 to 20 of 244 results

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Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

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Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity

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JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation

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The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

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Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells

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CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover

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The insider's guide to leukocyte integrin signalling and function

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Innate Response Activator B Cells Protect Against Microbial Sepsis

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Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration

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Integrin cross-talk modulates stiffness-independent motility of CD4+ T lymphocytes

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Recruitment of calcineurin to the TCR positively regulates T cell activation

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Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A

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The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling

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Foxp3⁺ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

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LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro

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Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

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Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson’s Disease

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‘Slings’ enable neutrophil rolling at high shear

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Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions

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Viral modulation of type II interferon increases T cell adhesion and virus spread

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