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ArticlesPeer ReviewedFull Text
Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution
Author / Creator:Youm, Yun-Hee ; Horvath, Tamas L. ; Mangelsdorf, David J. ; Kliewer, Steven A. ; Dixit, Vishwa Deep
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (4), p.1026-1031
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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
Author / Creator:Wei, Wei ; Dutchak, Paul A ; Wang, Xunde ; Ding, Xunshan ; Wang, Xueqian ; Bookout, Angie L ; Goetz, Regina ; Mohammadi, Moosa ; Gerard, Robert D ; Dechow, Paul C ; Mangelsdorf, David J ; Kliewer, Steven A ; Wan, Yihong
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.3143-3148
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Retinoid X Receptor Heterodimers in the Metabolic Syndrome
Author / Creator:Shulman, Andrew I ; Mangelsdorf, David J
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2005-08, Vol.353 (6), p.604-615
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FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
Author / Creator:Kir, Serkan ; Beddow, Sara A. ; Samuel, Varman T. ; Miller, Paul ; Previs, Stephen F. ; Suino-Powell, Kelly ; Xu, H. Eric ; Shulman, Gerald I. ; Kliewer, Steven A. ; Mangelsdorf, David J.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-03, Vol.331 (6024), p.1621-1624
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FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
Author / Creator:Potthoff, Matthew J ; Inagaki, Takeshi ; Satapati, Santhosh ; Ding, Xunshan ; He, Tianteng ; Goetz, Regina ; Mohammadi, Moosa ; Finck, Brian N ; Mangelsdorf, David J ; Kliewer, Steven A ; Burgess, Shawn C
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10853-10858
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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
Author / Creator:Zhang, Yuan ; Xie, Yang ; Berglund, Eric D ; Coate, Katie Colbert ; He, Tian Teng ; Katafuchi, Takeshi ; Xiao, Guanghua ; Potthoff, Matthew J ; Wei, Wei ; Wan, Yihong ; Yu, Ruth T ; Evans, Ronald M ; Kliewer, Steven A ; Mangelsdorf, David J
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2012-10, Vol.1, p.e00065-e00065
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ArticlesPeer ReviewedFull Text
Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid
Author / Creator:Albarqi, Mennatallah M Y ; Stoltzfus, Jonathan D ; Pilgrim, Adeiye A ; Nolan, Thomas J ; Wang, Zhu ; Kliewer, Steven A ; Mangelsdorf, David J ; Lok, James B
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-01, Vol.12 (1), p.e1005358-e1005358
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The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3
Author / Creator:Romero, Aracely A ; Cobb, Sarah A ; Collins, Julie N R ; Kliewer, Steven A ; Mangelsdorf, David J ; Collins, 3rd, James J
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2021-12, Vol.17 (12), p.e1010140-e1010140
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Regulation of Antibacterial Defense in the Small Intestine by the Nuclear Bile Acid Receptor
Author / Creator:Inagaki, Takeshi ; Moschettat, Antonio ; Lee, Youn-Kyoung ; Peng, Li ; Zhao, Guixiang ; Downes, Michael ; Yu, Ruth T. ; Shelton, John M. ; Richardson, James A. ; Repa, Joyce J. ; Mangelsdorf, David J. ; Kliewer, Steven A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (10), p.3920-3925
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ArticlesPeer ReviewedFull Text
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
Author / Creator:Joseph, Sean B. ; Castrillo, Antonio ; Laffitte, Bryan A. ; Mangelsdorf, David J. ; Tontonoz, Peter
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2003-02, Vol.9 (2), p.213-219
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Nuclear Receptors and Lipid Physiology: Opening the X-Files
Author / Creator:Chawla, Ajay ; Repa, Joyce J. ; Evans, Ronald M. ; Mangelsdorf, David J.
Publisher:United States: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5548), p.1866-1870
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ArticlesPeer ReviewedFull Text
Genetic Evidence That the Human CYP2R1 Enzyme Is a Key Vitamin D 25-Hydroxylase
Author / Creator:Cheng, Jeffrey B. ; Levine, Michael A. ; Bell, Norman H. ; Mangelsdorf, David J. ; Russell, David W. ; Wilson, Jean D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (20), p.7711-7715
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ArticlesPeer ReviewedFull Text
The nuclear receptor DAF-12 regulates nutrient metabolism and reproductive growth in nematodes
Author / Creator:Wang, Zhu ; Stoltzfus, Jonathan ; You, Young-Jai ; Ranjit, Najju ; Tang, Hao ; Xie, Yang ; Lok, James B ; Mangelsdorf, David J ; Kliewer, Steven A
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-03, Vol.11 (3), p.e1005027-e1005027
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ArticlesPeer ReviewedFull Text
bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
Author / Creator:Gerisch, Birgit ; Rottiers, Veerle ; Li, Dongling ; Motola, Daniel L ; Cummins, Carolyn L ; Lehrach, Hans ; Mangelsdorf, David J ; Antebi, Adam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.5014-5019
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ArticlesPeer ReviewedFull Text
Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer
Author / Creator:Jeong, Yangsik ; Xie, Yang ; Xiao, Guanghua ; Behrens, Carmen ; Girard, Luc ; Wistuba, Ignacio I ; Minna, John D ; Mangelsdorf, David J
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2010-12, Vol.7 (12), p.e1000378-e1000378
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The liver X receptor gene team: Potential new players in atherosclerosis
Author / Creator:Repa, Joyce J. ; Mangelsdorf, David J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2002-11, Vol.8 (11), p.1243-1248
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ArticlesPeer ReviewedFull Text
Identification of a hormonal basis for gallbladder filling
Author / Creator:Choi, Mihwa ; Moschetta, Antonio ; Bookout, Angie L ; Peng, Li ; Umetani, Michihisa ; Holmstrom, Sam R ; Suino-Powell, Kelly ; Xu, H Eric ; Richardson, James A ; Gerard, Robert D ; Mangelsdorf, David J ; Kliewer, Steven A
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2006-11, Vol.12 (11), p.1253-1255
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ArticlesPeer ReviewedFull Text
Vitamin D Receptor as an Intestinal Bile Acid Sensor
Author / Creator:Makishima, Makoto ; Lu, Timothy T. ; Xie, Wen ; Whitfield, G. Kerr ; Domoto, Hideharu ; Evans, Ronald M. ; Haussler, Mark R. ; Mangelsdorf, David J.
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5571), p.1313-1316
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Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation
Author / Creator:Ayoade, Katherine Omueti ; Carranza, Faith R ; Cho, Woong Hee ; Wang, Zhu ; Kliewer, Steven A ; Mangelsdorf, David J ; Stoltzfus, Jonathan D C
Publisher:England: BioMed Central Ltd
Journal title:Parasites & vectors, 2020-04, Vol.13 (1), p.162-162, Article 162
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Nuclear receptor regulation of stemness and stem cell differentiation
Author / Creator:Jeong, Yangsik ; Mangelsdorf, David J
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2009, 41(8), , pp.525-537
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Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution

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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

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Retinoid X Receptor Heterodimers in the Metabolic Syndrome

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FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

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FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

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Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid

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The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3

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Regulation of Antibacterial Defense in the Small Intestine by the Nuclear Bile Acid Receptor

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

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Nuclear Receptors and Lipid Physiology: Opening the X-Files

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Genetic Evidence That the Human CYP2R1 Enzyme Is a Key Vitamin D 25-Hydroxylase

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The nuclear receptor DAF-12 regulates nutrient metabolism and reproductive growth in nematodes

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bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling

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Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer

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The liver X receptor gene team: Potential new players in atherosclerosis

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Identification of a hormonal basis for gallbladder filling

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Vitamin D Receptor as an Intestinal Bile Acid Sensor

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Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

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Nuclear receptor regulation of stemness and stem cell differentiation

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