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Newsletter articlesFull Text
INTERNATIONAL PATENT: MOLINE, MARGARET , KRAMER, LYNN , DHADDA, SHOBHA FILES APPLICATION FOR "LEMBOREXANT FOR TREATING SLEEP ISSUES"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study
Author / Creator:Farlow, Martin R., MD ; Salloway, Stephen, MD, MS ; Tariot, Pierre N., MD ; Yardley, Jane, PhD ; Moline, Margaret L., PhD ; Wang, Qin, PhD ; Brand-Schieber, Elimor, PhD ; Zou, Heng, MS ; Hsu, Timothy, MD ; Satlin, Andrew, MD
Publisher:Bridgewater, NJ: EM Inc USA
Journal title:Clinical therapeutics, 2010-07, Vol.32 (7), p.1234-1251
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ArticlesPeer ReviewedFull Text
Effect of discontinuation of lemborexant following long‐term treatment of insomnia disorder: Secondary analysis of a randomized clinical trial
Author / Creator:Takaesu, Yoshikazu ; Suzuki, Masahiro ; Moline, Margaret ; Pinner, Kate ; Inabe, Kanako ; Nishi, Yurie ; Kuriyama, Kenichi
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2023-04, Vol.16 (4), p.581-592
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ArticlesPeer ReviewedFull Text
Cost-effectiveness analysis of lemborexant for treating insomnia in Japan: a model-based projection, incorporating the risk of falls, motor vehicle collisions, and workplace accidents
Author / Creator:Ikeda, Shunya ; Azuma, Mie Kasai ; Fujimoto, Kenichi ; Shibahara, Hidetoshi ; Inoue, Sachie ; Moline, Margaret ; Ishii, Mika ; Mishima, Kazuo
Publisher:Cambridge, UK: Cambridge University Press
Journal title:Psychological medicine, 2022-10, Vol.52 (13), p.2822-2834
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ArticlesPeer ReviewedFull Text
The ADAS-cog in Alzheimer's disease clinical trials: psychometric evaluation of the sum and its parts
Author / Creator:Cano, Stefan J ; Posner, Holly B ; Moline, Margaret L ; Hurt, Stephen W ; Swartz, Jina ; Hsu, Tim ; Hobart, Jeremy C
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal of neurology, neurosurgery and psychiatry, 2010-12, Vol.81 (12), p.1363-1368
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ArticlesPeer ReviewedFull Text
Cost-effectiveness analysis of lemborexant for treating insomnia in Japan: A model-based projection, incorporating the risk of falls, motor vehicle collisions, and workplace accidents – CORRIGENDUM
Author / Creator:Ikeda, Shunya ; Azuma, Mie Kasai ; Fujimoto, Kenichi ; Shibahara, Hidetoshi ; Inoue, Sachie ; Moline, Margaret ; Ishii, Mika ; Mishima, Kazuo
Publisher:England: Cambridge University Press (CUP)
Journal title:Psychological Medicine, 2022-10, Vol.52 (13), p.2847-2847
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ArticlesPeer ReviewedFull Text
On-the-road driving performance the morning after bedtime administration of lemborexant in healthy adult and elderly volunteers
Author / Creator:Vermeeren, Annemiek ; Jongen, Stefan ; Murphy, Patricia ; Moline, Margaret ; Filippov, Gleb ; Pinner, Kate ; Perdomo, Carlos ; Landry, Ishani ; Majid, Oneeb ; Van Oers, Anita C M ; Van Leeuwen, Cees J ; Ramaekers, Johannes G ; Vuurman, Eric F P M
Publisher:US: Oxford University Press
Journal title:Sleep (New York, N.Y.), 2019-04, Vol.42 (4), p.1
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ArticlesPeer ReviewedFull Text
The Association between Insomnia and Insomnia Treatment Side Effects on Health Status, Work Productivity, and Healthcare Resource Use
Author / Creator:DiBonaventura, Marco ; Richard, Lance ; Kumar, Maya ; Forsythe, Anna ; Flores, Natalia M. ; Moline, Margaret
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0137117
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ArticlesPeer ReviewedFull Text
Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group
Author / Creator:Wickwire, Emerson M. ; Williams, Scott G. ; Roth, Thomas ; Capaldi, Vincent F. ; Jaffe, Michael ; Moline, Margaret ; Motamedi, Gholam K. ; Morgan, Gregory W. ; Mysliwiec, Vincent ; Germain, Anne ; Pazdan, Renee M. ; Ferziger, Reuven ; Balkin, Thomas J. ; MacDonald, Margaret E. ; Macek, Thomas A. ; Yochelson, Michael R. ; Scharf, Steven M. ; Lettieri, Christopher J.
Publisher:New York: Springer US
Journal title:Neurotherapeutics, 2016-04, Vol.13 (2), p.403-417
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ArticlesPeer ReviewedFull Text
Evidence‐based insomnia treatment strategy using novel orexin antagonists: A review
Author / Creator:Kishi, Taro ; Nishida, Maika ; Koebis, Michinori ; Taninaga, Takehiro ; Muramoto, Kenzo ; Kubota, Naoki ; Moline, Margaret ; Sakuma, Kenji ; Okuya, Makoto ; Nomura, Ikuo ; Iwata, Nakao
Publisher:United States: John Wiley & Sons, Inc
Journal title:Neuropsychopharmacology reports, 2021-12, Vol.41 (4), p.450-458
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ArticlesPeer ReviewedFull Text
Efficacy of Lemborexant in Adults ≥ 65 Years of Age with Insomnia Disorder
Author / Creator:Arnold, Valerie ; Ancoli-Israel, Sonia ; Dang-Vu, Thien Thanh ; Mishima, Kazuo ; Pinner, Kate ; Malhotra, Manoj ; Moline, Margaret
Publisher:Cheshire: Springer Healthcare
Journal title:Neurology and therapy, 2024-08, Vol.13 (4), p.1081-1098
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ArticlesPeer ReviewedFull Text
Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL
Author / Creator:Dichgans, Martin, MD ; Markus, Hugh S, FRCP ; Salloway, Stephen, MD ; Verkkoniemi, Auli, MD ; Moline, Margaret, PhD ; Wang, Qin, PhD ; Posner, Holly, MD ; Chabriat, Hugues S, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2008-04, Vol.7 (4), p.310-318
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ArticlesPeer ReviewedFull Text
Comparison of Pharmacokinetic Profiles of Zolpidem Buffered Sublingual Tablet and Zolpidem Oral Immediate-Release Tablet: Results from a Single-Center, Single-Dose, Randomized, Open-Label Crossover St...
Author / Creator:Greenblatt, David J., MD ; Harmatz, Jerold S., AB ; Roth, Thomas, PhD ; Singh, Nikhilesh N., PhD ; Moline, Margaret L., PhD ; Harris, Stephen C., MD ; Kapil, Ram P., PhD
Publisher:Bridgewater, NJ: Elsevier Inc
Journal title:Clinical therapeutics, 2013-05, Vol.35 (5), p.604-611
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ArticlesPeer ReviewedFull Text
Safety and tolerability of donepezil 23 mg in moderate to severe Alzheimer's disease
Author / Creator:Farlow, Martin ; Veloso, Felix ; Moline, Margaret ; Yardley, Jane ; Brand-Schieber, Elimor ; Bibbiani, Francesco ; Zou, Heng ; Hsu, Timothy ; Satlin, Andrew
Publisher:England: BioMed Central Ltd
Journal title:BMC neurology, 2011-05, Vol.11 (1), p.57-57, Article 57
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ArticlesPeer ReviewedFull Text
Efficacy and safety of lemborexant in subjects with insomnia disorder receiving medications for depression or anxiety symptoms
Author / Creator:Krystal, Andrew ; Blier, Pierre ; Culpepper, Larry ; Nierenberg, Andrew A. ; Takaesu, Yoshikazu ; Kubota, Naoki ; Moline, Margaret ; Malhotra, Manoj ; Pinner, Kate ; Yardley, Jane
Publisher:United States: John Wiley & Sons, Inc
Journal title:Neuropsychopharmacology reports, 2025-03, Vol.45 (1), p.e12509-n/a
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ArticlesPeer ReviewedFull Text
Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials...
Author / Creator:Lenderking, William R. ; Savva, Yulia ; Atkinson, Mark J. ; Campbell, Renee ; Chabot, Isabelle ; Moline, Margaret ; Meier, Genevieve ; Morin, Charles M.
Publisher:Cham: Springer International Publishing
Journal title:Journal of patient-reported outcomes, 2024-06, Vol.8 (1), p.65-12, Article 65
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ArticlesPeer ReviewedFull Text
Effect of hepatic impairment on pharmacokinetics, safety, and tolerability of lemborexant
Author / Creator:Dayal, Satish ; Aluri, Jagadeesh ; Hall, Nancy ; Filippov, Gleb ; Moline, Margaret ; Reyderman, Larisa ; Landry, Ishani
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2021-04, Vol.9 (2), p.e00758-n/a
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ArticlesPeer ReviewedFull Text
Effect of gastric acid‐reducing agents on the pharmacokinetics and efficacy of lemborexant
Author / Creator:Landry, Ishani ; Aluri, Jagadeesh ; Hall, Nancy ; Kumar, Dinesh ; Dayal, Satish ; Moline, Margaret ; Reyderman, Larisa
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2020-12, Vol.8 (6), p.e00678-n/a
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ArticlesPeer ReviewedFull Text
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Author / Creator:Landry, Ishani ; Aluri, Jagadeesh ; Hall, Nancy ; Filippov, Gleb ; Dayal, Satish ; Moline, Margaret ; Reyderman, Larisa
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2021-04, Vol.9 (2), p.e00734-n/a
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ArticlesPeer ReviewedFull Text
Long-term safety and tolerability of donepezil 23 mg in patients with moderate to severe Alzheimer’s disease
Author / Creator:Tariot, Pierre ; Salloway, Steven ; Yardley, Jane ; Mackell, Joan ; Moline, Margaret
Publisher:England: BioMed Central Ltd
Journal title:BMC research notes, 2012-06, Vol.5 (1), p.283-283, Article 283
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INTERNATIONAL PATENT: MOLINE, MARGARET , KRAMER, LYNN , DHADDA, SHOBHA FILES APPLICATION FOR "LEMBOREXANT FOR TREATING SLEEP ISSUES"

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Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study

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Effect of discontinuation of lemborexant following long‐term treatment of insomnia disorder: Secondary analysis of a randomized clinical trial

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Cost-effectiveness analysis of lemborexant for treating insomnia in Japan: a model-based projection, incorporating the risk of falls, motor vehicle collisions, and workplace accidents

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The ADAS-cog in Alzheimer's disease clinical trials: psychometric evaluation of the sum and its parts

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Cost-effectiveness analysis of lemborexant for treating insomnia in Japan: A model-based projection, incorporating the risk of falls, motor vehicle collisions, and workplace accidents – CORRIGENDUM

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On-the-road driving performance the morning after bedtime administration of lemborexant in healthy adult and elderly volunteers

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The Association between Insomnia and Insomnia Treatment Side Effects on Health Status, Work Productivity, and Healthcare Resource Use

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Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group

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Evidence‐based insomnia treatment strategy using novel orexin antagonists: A review

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Efficacy of Lemborexant in Adults ≥ 65 Years of Age with Insomnia Disorder

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Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL

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Comparison of Pharmacokinetic Profiles of Zolpidem Buffered Sublingual Tablet and Zolpidem Oral Immediate-Release Tablet: Results from a Single-Center, Single-Dose, Randomized, Open-Label Crossover St...

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Safety and tolerability of donepezil 23 mg in moderate to severe Alzheimer's disease

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Efficacy and safety of lemborexant in subjects with insomnia disorder receiving medications for depression or anxiety symptoms

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Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials...

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Effect of hepatic impairment on pharmacokinetics, safety, and tolerability of lemborexant

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Effect of gastric acid‐reducing agents on the pharmacokinetics and efficacy of lemborexant

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Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant

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Long-term safety and tolerability of donepezil 23 mg in patients with moderate to severe Alzheimer’s disease

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