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ArticlesPeer ReviewedFull Text
Guidelines for morpholino use in zebrafish
Author / Creator:Stainier, Didier Y. R. ; Raz, Erez ; Lawson, Nathan D. ; Ekker, Stephen C. ; Burdine, Rebecca D. ; Eisen, Judith S. ; Ingham, Philip W. ; Schulte-Merker, Stefan ; Yelon, Deborah ; Weinstein, Brant M. ; Mullins, Mary C. ; Wilson, Stephen W. ; Ramakrishnan, Lalita ; Amacher, Sharon L. ; Neuhauss, Stephan C. F. ; Meng, Anming ; Mochizuki, Naoki ; Panula, Pertti ; Moens, Cecilia B.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2017-10, Vol.13 (10), p.e1007000
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Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development
Author / Creator:Kloosterman, Wigard P ; Lagendijk, Anne K ; Ketting, René F ; Moulton, Jon D ; Plasterk, Ronald H. A
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2007-08, Vol.5 (8), p.e203-e203
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Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy
Author / Creator:Echigoya, Yusuke ; Nakamura, Akinori ; Nagata, Tetsuya ; Urasawa, Nobuyuki ; Lim, Kenji Rowel Q. ; Trieu, Nhu ; Panesar, Dharminder ; Kuraoka, Mutsuki ; Moulton, Hong M. ; Saito, Takashi ; Aoki, Yoshitsugu ; Iversen, Patrick ; Sazani, Peter ; Kole, Ryszard ; Maruyama, Rika ; Partridge, Terry ; Takeda, Shin’ichi ; Yokota, Toshifumi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (16), p.4213-4218
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Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers
Author / Creator:Li, Chengxi ; Callahan, Alex J. ; Simon, Mark D. ; Totaro, Kyle A. ; Mijalis, Alexander J. ; Phadke, Kruttika-Suhas ; Zhang, Genwei ; Hartrampf, Nina ; Schissel, Carly K. ; Zhou, Ming ; Zong, Hong ; Hanson, Gunnar J. ; Loas, Andrei ; Pohl, Nicola L. B. ; Verhoeven, David E. ; Pentelute, Bradley L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4396-8, Article 4396
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Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics
Author / Creator:Chen, Jennifer CJ ; King, Oliver D ; Zhang, Yuanfan ; Clayton, Nicholas P ; Spencer, Carrie ; Wentworth, Bruce M ; Emerson, Charles P ; Wagner, Kathryn R
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2016-08, Vol.24 (8), p.1405-1411
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Synthesis of Backbone-Modified Morpholino Oligonucleotides Using Phosphoramidite Chemistry
Author / Creator:Paul, Sibasish ; Caruthers, Marvin H.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-07, Vol.28 (14), p.5380
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Expression of Concern: Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2022-04, Vol.20 (4), p.e3001631-e3001631
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ArticlesPeer ReviewedFull Text
In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
Author / Creator:Aung-Htut, May T. ; McIntosh, Craig S. ; West, Kristin A. ; Fletcher, Sue ; Wilton, Steve D.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-08, Vol.24 (16), p.2922
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Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study
Author / Creator:Cirak, Sebahattin, MD ; Arechavala-Gomeza, Virginia, PhD ; Guglieri, Michela, MD ; Feng, Lucy, PhD ; Torelli, Silvia, PhD ; Anthony, Karen, PhD ; Abbs, Stephen, PhD ; Garralda, Maria Elena, Prof ; Bourke, John, MD ; Wells, Dominic J, Prof ; Dickson, George, Prof ; Wood, Matthew JA, MD PhD ; Wilton, Steve D, Prof ; Straub, Volker, Prof ; Kole, Ryszard, Prof ; Shrewsbury, Stephen B, MD ; Sewry, Caroline, Prof ; Morgan, Jennifer E, PhD ; Bushby, Kate, Prof ; Muntoni, Francesco, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2011-08, Vol.378 (9791), p.595-605
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ArticlesPeer ReviewedFull Text
Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45–55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice
Author / Creator:Echigoya, Yusuke ; Aoki, Yoshitsugu ; Miskew, Bailey ; Panesar, Dharminder ; Touznik, Aleksander ; Nagata, Tetsuya ; Tanihata, Jun ; Nakamura, Akinori ; Nagaraju, Kanneboyina ; Yokota, Toshifumi
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2015-02, Vol.4 (2), p.e225-e225, Article e225
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ArticlesPeer ReviewedFull Text
Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo
Author / Creator:Tarbashevich, Katsiaryna ; Ghosh, Atanu ; Das, Arnab ; Kuilya, Debajyoti ; Sharma, Swrajit Nath ; Sinha, Surajit ; Raz, Erez
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3614-11, Article 3614
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ArticlesPeer ReviewedFull Text
Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis
Author / Creator:Layden, Michael J ; Röttinger, Eric ; Wolenski, Francis S ; Gilmore, Thomas D ; Martindale, Mark Q
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2013-05, Vol.8 (5), p.924-934
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Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes
Author / Creator:Eve, Alexander M. J. ; Place, Elsie S. ; Smith, James C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-02, Vol.12 (2), p.e0172227-e0172227
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Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide
Author / Creator:Chen, Suxiang ; Le, Bao ; Rahimizadeh, Kamal ; Shaikh, Khalil ; Mohal, Narinder ; Veedu, Rakesh
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2016-11, Vol.21 (11), p.1582-1582
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ArticlesPeer ReviewedFull Text
Convergent synthesis of phosphorodiamidate morpholino oligonucleotides (PMOs) by the H-phosphonate approach
Author / Creator:Tsurusaki, Taiki ; Sato, Kazuki ; Imai, Hiroki ; Hirai, Kunihiro ; Takahashi, Daisuke ; Wada, Takeshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-08, Vol.13 (1), p.12576-12576, Article 12576
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Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice
Author / Creator:Mukashyaka, Marie Claire ; Wu, Chia-Ling ; Ha, Kristin ; Zhang, Jianbo ; Wood, Jenna ; Foley, Samantha ; Mastis, Bryan ; Jungels, Nino ; Sun, Huadong ; Shadid, Mohammad ; Harriman, Shawn ; Hadcock, John R.
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2021-10, Vol.38 (10), p.1731-1745
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Reference EntriesFull Text
Morpholinos
Publisher:Oxford University Press
Journal title:A Dictionary of Genetics, 2013
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ArticlesPeer ReviewedFull Text
Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse model
Author / Creator:Hasegawa, Juri ; Nagata, Tetsuya ; Ihara, Kensuke ; Tanihata, Jun ; Ebihara, Satoe ; Yoshida-Tanaka, Kie ; Yanagidaira, Mitsugu ; Ohara, Masahiro ; Sasaki, Asuka ; Nakayama, Miyu ; Yamamoto, Syunsuke ; Ishii, Takashi ; Iwata-Hara, Rintaro ; Naito, Mitsuru ; Miyata, Kanjiro ; Sakaue, Fumika ; Yokota, Takanori
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.7530-15, Article 7530
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Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice
Author / Creator:Gao, Xianjun ; Zhao, Jingwen ; Han, Gang ; Zhang, Yajie ; Dong, Xue ; Cao, Limin ; Wang, Qingsong ; Moulton, Hong M ; Yin, HaiFang
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2014-07, Vol.22 (7), p.1333-1341
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Enhanced Protection of Carbon Steel Against Acid Corrosion: Synergistic Effect of s‐Triazine‐Anilino‐Morpholino‐Pyrazolyl Hybrids Through Electrochemical and Computational Insights
Author / Creator:Shawish, Ihab ; Hammud, Hassan H. ; Aljamhi, Waleed A. ; El‐Lateef, Hany M. Abd ; Arfan, Nur Hazimah B. Z. ; Hamid, Malai Haniti S. A. ; Sheikh, Nadeem S. ; Alayoubi, Samha ; Bououdina, Mohamed ; Barakat, Assem ; El‐Faham, Ayman
Publisher:Weinheim: John Wiley & Sons, Inc
Journal title:ChemElectroChem, 2025-04, Vol.12 (7), p.n/a
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Showing 1 to 20 of 2,949 results

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Guidelines for morpholino use in zebrafish

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Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

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Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy

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Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers

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Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics

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Synthesis of Backbone-Modified Morpholino Oligonucleotides Using Phosphoramidite Chemistry

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Expression of Concern: Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

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In Vitro Validation of Phosphorodiamidate Morpholino Oligomers

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Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

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Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45–55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice

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Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo

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Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis

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Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes

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Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

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Convergent synthesis of phosphorodiamidate morpholino oligonucleotides (PMOs) by the H-phosphonate approach

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Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice

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Morpholinos

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Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse model

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Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

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Enhanced Protection of Carbon Steel Against Acid Corrosion: Synergistic Effect of s‐Triazine‐Anilino‐Morpholino‐Pyrazolyl Hybrids Through Electrochemical and Computational Insights

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