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53 results for Myeloid+Progenitor+Cells+-+pathology

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ArticlesPeer ReviewedFull Text
Tracing the origins of relapse in acute myeloid leukaemia to stem cells
Author / Creator:Shlush, Liran I. ; Mitchell, Amanda ; Heisler, Lawrence ; Abelson, Sagi ; Ng, Stanley W. K. ; Trotman-Grant, Aaron ; Medeiros, Jessie J. F. ; Rao-Bhatia, Abilasha ; Jaciw-Zurakowsky, Ivana ; Marke, Rene ; McLeod, Jessica L. ; Doedens, Monica ; Bader, Gary ; Voisin, Veronique ; Xu, ChangJiang ; McPherson, John D. ; Hudson, Thomas J. ; Wang, Jean C. Y. ; Minden, Mark D. ; Dick, John E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-07, Vol.547 (7661), p.104-108
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Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
Author / Creator:Wang, Liguo ; Shao, Xuejing ; Zhong, Tianbai ; Wu, Yue ; Xu, Aixiao ; Sun, Xiuyun ; Gao, Hongying ; Liu, Yongbo ; Lan, Tianlong ; Tong, Yan ; Tao, Xue ; Du, Wenxin ; Wang, Wei ; Chen, Yingqian ; Li, Ting ; Meng, Xianbin ; Deng, Haiteng ; Yang, Bo ; He, Qiaojun ; Ying, Meidan ; Rao, Yu
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2021-05, Vol.17 (5), p.567-575
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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
Author / Creator:Mass, Elvira ; Jacome-Galarza, Christian E. ; Blank, Thomas ; Lazarov, Tomi ; Durham, Benjamin H. ; Ozkaya, Neval ; Pastore, Alessandro ; Schwabenland, Marius ; Chung, Young Rock ; Rosenblum, Marc K. ; Prinz, Marco ; Abdel-Wahab, Omar ; Geissmann, Frederic
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-09, Vol.549 (7672), p.389-393
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Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis
Author / Creator:Loberg, Matthew A. ; Bell, Rebecca K. ; Goodwin, Leslie O. ; Eudy, Elizabeth ; Miles, Linde A. ; SanMiguel, Jennifer M. ; Young, Kira ; Bergstrom, David E. ; Levine, Ross L. ; Schneider, Rebekka K. ; Trowbridge, Jennifer J.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2019-07, Vol.33 (7), p.1635-1649
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Somatic SETBP1 mutations in myeloid malignancies
Author / Creator:Makishima, Hideki ; Yoshida, Kenichi ; Nguyen, Nhu ; Przychodzen, Bartlomiej ; Sanada, Masashi ; Okuno, Yusuke ; Ng, Kwok Peng ; Gudmundsson, Kristbjorn O ; Vishwakarma, Bandana A ; Jerez, Andres ; Gomez-Segui, Ines ; Takahashi, Mariko ; Shiraishi, Yuichi ; Nagata, Yasunobu ; Guinta, Kathryn ; Mori, Hiraku ; Sekeres, Mikkael A ; Chiba, Kenichi ; Tanaka, Hiroko ; Muramatsu, Hideki ; Sakaguchi, Hirotoshi ; Paquette, Ronald L ; McDevitt, Michael A ; Kojima, Seiji ; Saunthararajah, Yogen ; Miyano, Satoru ; Shih, Lee-Yung ; Du, Yang ; Ogawa, Seishi ; Maciejewski, Jaroslaw P
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-08, Vol.45 (8), p.942-946
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ArticlesPeer ReviewedFull Text
Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance
Author / Creator:Zhang, Lianjun ; Nguyen, Le Xuan Truong ; Chen, Ying-Chieh ; Wu, Dijiong ; Cook, Guerry J. ; Hoang, Dinh Hoa ; Brewer, Casey J. ; He, Xin ; Dong, Haojie ; Li, Shu ; Li, Man ; Zhao, Dandan ; Qi, Jing ; Hua, Wei-Kai ; Cai, Qi ; Carnahan, Emily ; Chen, Wei ; Wu, Xiwei ; Swiderski, Piotr ; Rockne, Russell C. ; Kortylewski, Marcin ; Li, Ling ; Zhang, Bin ; Marcucci, Guido ; Kuo, Ya-Huei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.6154-6154, Article 6154
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MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors
Author / Creator:Chen, Xinyue ; Burkhardt, Daniel B. ; Hartman, Amaleah A. ; Hu, Xiao ; Eastman, Anna E. ; Sun, Chao ; Wang, Xujun ; Zhong, Mei ; Krishnaswamy, Smita ; Guo, Shangqin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5767-15, Article 5767
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ArticlesPeer ReviewedFull Text
Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases
Author / Creator:Chiba, Yukino ; Mizoguchi, Izuru ; Hasegawa, Hideaki ; Ohashi, Mio ; Orii, Naoko ; Nagai, Taro ; Sugahara, Miyaka ; Miyamoto, Yasunori ; Xu, Mingli ; Owaki, Toshiyuki ; Yoshimoto, Takayuki
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2018-04, Vol.75 (8), p.1363-1376
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ArticlesPeer ReviewedFull Text
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells
Author / Creator:Vu, Ly P ; Prieto, Camila ; Amin, Elianna M ; Chhangawala, Sagar ; Krivtsov, Andrei ; Calvo-Vidal, M Nieves ; Chou, Timothy ; Chow, Arthur ; Minuesa, Gerard ; Park, Sun Mi ; Barlowe, Trevor S ; Taggart, James ; Tivnan, Patrick ; Deering, Raquel P ; Chu, Lisa P ; Kwon, Jeong-Ah ; Meydan, Cem ; Perales-Paton, Javier ; Arshi, Arora ; Gönen, Mithat ; Famulare, Christopher ; Patel, Minal ; Paietta, Elisabeth ; Tallman, Martin S ; Lu, Yuheng ; Glass, Jacob ; Garret-Bakelman, Francine E ; Melnick, Ari ; Levine, Ross ; Al-Shahrour, Fatima ; Järås, Marcus ; Hacohen, Nir ; Hwang, Alexia ; Garippa, Ralph ; Lengner, Christopher J ; Armstrong, Scott A ; Cerchietti, Leandro ; Cowley, Glenn S ; Root, David ; Doench, John ; Leslie, Christina ; Ebert, Benjamin L ; Kharas, Michael G
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-06, Vol.49 (6), p.866-875
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ArticlesPeer ReviewedFull Text
A deconvolution method and its application in analyzing the cellular fractions in acute myeloid leukemia samples
Author / Creator:Li, Huamei ; Sharma, Amit ; Ming, Wenglong ; Sun, Xiao ; Liu, Hongde
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2020-09, Vol.21 (1), p.652-652, Article 652
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ArticlesPeer ReviewedFull Text
Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1
Author / Creator:Molstad, David H. H. ; Zars, Elizabeth ; Norton, Andrew ; Mansky, Kim C. ; Westendorf, Jennifer J. ; Bradley, Elizabeth W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.21804-15, Article 21804
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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors
Author / Creator:Neo, Wen Hao ; Meng, Yiran ; Rodriguez-Meira, Alba ; Fadlullah, Muhammad Z. H. ; Booth, Christopher A. G. ; Azzoni, Emanuele ; Thongjuea, Supat ; de Bruijn, Marella F. T. R. ; Jacobsen, Sten Eirik W. ; Mead, Adam J. ; Lacaud, Georges
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7019-7019, Article 7019
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ArticlesPeer ReviewedFull Text
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
Author / Creator:Wang, Zhong ; Smith, Kevin S. ; Murphy, Mark ; Piloto, Obdulio ; Somervaille, Tim C. P. ; Cleary, Michael L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2008-10, Vol.455 (7217), p.1205-1209
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ArticlesPeer ReviewedFull Text
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells
Author / Creator:Redondo Monte, Enric ; Wilding, Anja ; Leubolt, Georg ; Kerbs, Paul ; Bagnoli, Johannes W. ; Hartmann, Luise ; Hiddemann, Wolfgang ; Chen-Wichmann, Linping ; Krebs, Stefan ; Blum, Helmut ; Cusan, Monica ; Vick, Binje ; Jeremias, Irmela ; Enard, Wolfgang ; Theurich, Sebastian ; Wichmann, Christian ; Greif, Philipp A.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-04, Vol.39 (15), p.3195-3205
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ArticlesPeer ReviewedFull Text
The myelodysplastic syndromes flow cytometric score: a three-parameter prognostic flow cytometric scoring system
Author / Creator:Alhan, C ; Westers, T M ; Cremers, E M P ; Cali, C ; Witte, B I ; Ossenkoppele, G J ; van de Loosdrecht, A A
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2016-03, Vol.30 (3), p.658-665
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ArticlesPeer ReviewedFull Text
MEK inhibition exerts temporal and myeloid cell-specific effects in the pathogenesis of neurofibromatosis type 1 arteriopathy
Author / Creator:Tritz, Rebekah ; Hudson, Farlyn Z. ; Harris, Valerie ; Ghoshal, Pushpankur ; Singla, Bhupesh ; Lin, Huiping ; Csanyi, Gabor ; Stansfield, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-12, Vol.11 (1), p.24345-24345, Article 24345
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ArticlesPeer ReviewedFull Text
Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis
Author / Creator:Kreisel, Daniel ; Sugimoto, Seiichiro ; Tietjens, Jeremy ; Zhu, Jihong ; Yamamoto, Sumiharu ; Krupnick, Alexander S ; Carmody, Ruaidhri J ; Gelman, Andrew E
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-01, Vol.121 (1), p.265-276
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ArticlesPeer ReviewedFull Text
Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans
Author / Creator:Park, Sung O ; Wamsley, Heather L ; Bae, Kyungmi ; Hu, Zhongbo ; Li, Xiaomiao ; Choe, Se-woon ; Slayton, William B ; Oh, S Paul ; Wagner, Kay-Uwe ; Sayeski, Peter P
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-03, Vol.8 (3), p.e59675
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ArticlesPeer ReviewedFull Text
HoxA9 binds and represses the Cebpa +8 kb enhancer
Author / Creator:Peng, Lei ; Guo, Hong ; Ma, Peilin ; Sun, Yuqing ; Dennison, Lauren ; Aplan, Peter D ; Hess, Jay L ; Friedman, Alan D
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-05, Vol.14 (5), p.e0217604-e0217604
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Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia
Author / Creator:De Luca, Luciana ; Trino, Stefania ; Laurenzana, Ilaria ; Tagliaferri, Daniela ; Falco, Geppino ; Grieco, Vitina ; Bianchino, Gabriella ; Nozza, Filomena ; Campia, Valentina ; D'Alessio, Francesca ; La Rocca, Francesco ; Caivano, Antonella ; Villani, Oreste ; Cilloni, Daniela ; Musto, Pellegrino ; Del Vecchio, Luigi
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2017-06, Vol.8 (6), p.e2849-e2849
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Showing 1 to 20 of 53 results

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Tracing the origins of relapse in acute myeloid leukaemia to stem cells

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Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

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Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis

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Somatic SETBP1 mutations in myeloid malignancies

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Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance

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MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors

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Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases

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Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

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A deconvolution method and its application in analyzing the cellular fractions in acute myeloid leukemia samples

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Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1

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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

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Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy

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ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells

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The myelodysplastic syndromes flow cytometric score: a three-parameter prognostic flow cytometric scoring system

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MEK inhibition exerts temporal and myeloid cell-specific effects in the pathogenesis of neurofibromatosis type 1 arteriopathy

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Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

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Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans

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HoxA9 binds and represses the Cebpa +8 kb enhancer

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Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia

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