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ArticlesPeer ReviewedFull Text
Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Author / Creator:Bos, Rinke ; Rutten, Lucy ; van der Lubbe, Joan E. M. ; Bakkers, Mark J. G. ; Hardenberg, Gijs ; Wegmann, Frank ; Zuijdgeest, David ; de Wilde, Adriaan H. ; Koornneef, Annemart ; Verwilligen, Annemiek ; van Manen, Danielle ; Kwaks, Ted ; Vogels, Ronald ; Dalebout, Tim J. ; Myeni, Sebenzile K. ; Kikkert, Marjolein ; Snijder, Eric J. ; Li, Zhenfeng ; Barouch, Dan H. ; Vellinga, Jort ; Langedijk, Johannes P. M. ; Zahn, Roland C. ; Custers, Jerome ; Schuitemaker, Hanneke
Publisher:London: Nature Publishing Group UK
Journal title:npj vaccines, 2020-09, Vol.5 (1), p.91, Article 91
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Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase
Author / Creator:Myeni, Sebenzile K. ; Bredenbeek, Peter J. ; Knaap, Robert C. M. ; Dalebout, Tim J. ; Morales, Shessy Torres ; Sidorov, Igor A. ; Linger, Marissa E. ; Oreshkova, Nadia ; van Zanen-Gerhardt, Sophie ; Zander, Serge A. L. ; Enjuanes, Luis ; Sola, Isabel ; Snijder, Eric J. ; Kikkert, Marjolein
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1141-1141, Article 1141
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SipB-SipC complex is essential for translocon formation
Author / Creator:Myeni, Sebenzile K ; Wang, Lu ; Zhou, Daoguo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-03, Vol.8 (3), p.e60499-e60499
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Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity
Author / Creator:Rutten, Lucy ; Swart, Maarten ; Koornneef, Annemart ; Bouchier, Pascale ; Blokland, Sven ; Sadi, Ava ; Juraszek, Jarek ; Vijayan, Aneesh ; Schmit-Tillemans, Sonja ; Verspuij, Johan ; Choi, Ying ; Daal, Chenandly E. ; Perkasa, Aditya ; Torres Morales, Shessy ; Myeni, Sebenzile K. ; Kikkert, Marjolein ; Tolboom, Jeroen ; van Manen, Daniëlle ; Kuipers, Harmjan ; Schuitemaker, Hanneke ; Zahn, Roland ; Langedijk, Johannes P. M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-03, Vol.14 (1), p.5735-5735, Article 5735
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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
Author / Creator:van Huizen, Mariska ; Bloeme-Ter Horst, Jonna R ; de Gruyter, Heidi L M ; Geurink, Paul P ; van der Heden van Noort, Gerbrand J ; Knaap, Robert C M ; Nelemans, Tessa ; Ogando, Natacha S ; Leijs, Anouk A ; Urakova, Nadya ; Mark, Brian L ; Snijder, Eric J ; Myeni, Sebenzile K ; Kikkert, Marjolein
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-03, Vol.20 (3), p.e1012100-e1012100
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The Main Protease of Middle East Respiratory Syndrome Coronavirus Induces Cleavage of Mitochondrial Antiviral Signaling Protein to Antagonize the Innate Immune Response
Author / Creator:van Huizen, Mariska ; Vendrell, Xavier M ; de Gruyter, Heidi L M ; Boomaars-van der Zanden, A Linda ; van der Meer, Yvonne ; Snijder, Eric J ; Kikkert, Marjolein ; Myeni, Sebenzile K
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-02, Vol.16 (2), p.256
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Protection of K18-hACE2 Mice against SARS-CoV-2 Challenge by a Capsid Virus-like Particle-Based Vaccine
Author / Creator:Myeni, Sebenzile K ; Leijs, Anouk A ; Bredenbeek, Peter J ; Morales, Shessy Torres ; Linger, Marissa E ; Fougeroux, Cyrielle ; van Zanen-Gerhardt, Sophie ; Zander, Serge A L ; Sander, Adam F ; Kikkert, Marjolein
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2024-07, Vol.12 (7), p.766
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A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses
Author / Creator:Oreshkova, Nadia ; Myeni, Sebenzile K ; Mishra, Niraj ; Albulescu, Irina C ; Dalebout, Tim J ; Snijder, Eric J ; Bredenbeek, Peter J ; Dallmeier, Kai ; Kikkert, Marjolein
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2021-12, Vol.9 (12), p.1492
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ArticlesPeer ReviewedFull Text
HCoV-229E Mpro Suppresses RLR-Mediated Innate Immune Signalling Through Cleavage of NEMO and Through Other Mechanisms
Author / Creator:Martiáñez-Vendrell, Xavier ; van Kasteren, Puck B ; Myeni, Sebenzile K ; Kikkert, Marjolein
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (3), p.1197
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ArticlesPeer ReviewedFull Text
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection
Author / Creator:Pardieck, Iris N. ; van der Sluis, Tetje C. ; van der Gracht, Esmé T. I. ; Veerkamp, Dominique M. B. ; Behr, Felix M. ; van Duikeren, Suzanne ; Beyrend, Guillaume ; Rip, Jasper ; Nadafi, Reza ; Beyranvand Nejad, Elham ; Mülling, Nils ; Brasem, Dena J. ; Camps, Marcel G. M. ; Myeni, Sebenzile K. ; Bredenbeek, Peter J. ; Kikkert, Marjolein ; Kim, Yeonsu ; Cicin-Sain, Luka ; Abdelaal, Tamim ; van Gisbergen, Klaas P. J. M. ; Franken, Kees L. M. C. ; Drijfhout, Jan Wouter ; Melief, Cornelis J. M. ; Zondag, Gerben C. M. ; Ossendorp, Ferry ; Arens, Ramon
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.3966-3966, Article 3966
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ArticlesPeer ReviewedFull Text
Humoral response to SARS-CoV-2 infection among liver transplant recipients
Author / Creator:Becchetti, Chiara ; Broekhoven, Annelotte G C ; Dahlqvist, Géraldine ; Fraga, Montserrat ; Zambelli, Marco Fabrizio ; Ciccarelli, Olga ; Saouli, Anne-Catherine ; Trizzino, Arianna ; Banz, Vanessa ; Dufour, Jean-François ; Roukens, Anna H E ; Torres Morales, Shessy P ; Myeni, Sebenzile K ; Kikkert, Marjolein ; Feltkamp, Mariet C W ; Coenraad, Minneke J
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2022-04, Vol.71 (4), p.746-756
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ArticlesPeer ReviewedFull Text
Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease
Author / Creator:van der Lubbe, Joan E. M. ; Rosendahl Huber, Sietske K. ; Vijayan, Aneesh ; Dekking, Liesbeth ; van Huizen, Ella ; Vreugdenhil, Jessica ; Choi, Ying ; Baert, Miranda R. M. ; Feddes-de Boer, Karin ; Izquierdo Gil, Ana ; van Heerden, Marjolein ; Dalebout, Tim J. ; Myeni, Sebenzile K. ; Kikkert, Marjolein ; Snijder, Eric J. ; de Waal, Leon ; Stittelaar, Koert J. ; Tolboom, Jeroen T. B. M. ; Serroyen, Jan ; Muchene, Leacky ; van der Fits, Leslie ; Rutten, Lucy ; Langedijk, Johannes P. M. ; Barouch, Dan H. ; Schuitemaker, Hanneke ; Zahn, Roland C. ; Wegmann, Frank
Publisher:London: Nature Publishing Group UK
Journal title:npj vaccines, 2021-03, Vol.6 (1), p.39-12, Article 39
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ArticlesPeer ReviewedFull Text
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19
Author / Creator:Roukens, Anna H. E. ; Pothast, Cilia R. ; König, Marion ; Huisman, Wesley ; Dalebout, Tim ; Tak, Tamar ; Azimi, Shohreh ; Kruize, Yvonne ; Hagedoorn, Renate S. ; Zlei, Mihaela ; Staal, Frank J. T. ; de Bie, Fenna J. ; van Dongen, Jacques J. M. ; Arbous, Sesmu M. ; Zhang, Jaimie L. H. ; Verheij, Maaike ; Prins, Corine ; van der Does, Anne M. ; Hiemstra, Pieter S. ; de Vries, Jutte J. C. ; Janse, Jacqueline J. ; Roestenberg, Meta ; Myeni, Sebenzile K. ; Kikkert, Marjolein ; Yazdanbakhsh, Maria ; Heemskerk, Mirjam H. M. ; Smits, Hermelijn H. ; Jochems, Simon P.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-01, Vol.23 (1), p.23-32
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ArticlesFull Text
A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies
Author / Creator:Pardieck, Iris N ; Esme Ti Van Der Gracht ; Veerkamp, Dominique Mb ; Behr, Felix M ; Suzanne Van Duikeren ; Beyrend, Guillaume ; Rip, Jasper ; Nadafi, Reza ; Tetje C Van Der Sluis ; Nejad, Elham Beyranvand ; Mulling, Nils ; Brasem, Dena J ; Camps, Marcel Gm ; Myeni, Sebenzile K ; Bredenbeek, Peter J ; Kikkert, Marjolein ; Kim, Yeonsu ; Cicin-Sain, Luka ; Abdelaal, Tamim ; Klaas Pjm Van Gisbergen ; Franken, Kees Lmc ; Jan Wouter Drijfhout ; Melief, Cornelius Jm ; Zondag, Gerben Cm ; Ferry Ossendorp ; Arens, Ramon
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-12
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ArticlesPeer ReviewedFull Text
Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance
Author / Creator:Zlei, Mihaela ; Sidorov, Igor A ; Joosten, Simone A ; Heemskerk, Mirjam H M ; Myeni, Sebenzile K ; Pothast, Cilia R ; de Brouwer, Caroline S ; Boomaars-van der Zanden, A Linda ; van Meijgaarden, Krista E ; Morales, Shessy T ; Wessels, Els ; Janse, Jacqueline J ; Goeman, Jelle J ; Cobbaert, Christa M ; Kroes, Aloys C M ; Cannegieter, Suzanne C ; Roestenberg, Meta ; Visser, Leonardus G ; Kikkert, Marjolein ; Feltkamp, Mariet C W ; Arbous, Sesmu M ; Staal, Frank J T ; Ottenhoff, Tom H M ; van Dongen, Jacques J M ; Roukens, Anna H E ; de Vries, Jutte J C ; In Collaboration With Beat-Covid ; In Collaboration With Lumc Covid
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-09, Vol.11 (17), p.2743
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ArticlesFull Text
Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Author / Creator:Bos, Rinke ; Rutten, Lucy ; Joan Em Van Der Lubbe ; Bakkers, Mark Jg ; Hardenberg, Gijs ; Wegmann, Frank ; Zuijdgeest, David ; De Wilde, Adriaan H ; Koornneef, Annemart ; Verwilligen, Annemiek ; Danielle Van Manen ; Kwaks, Ted ; Vogels, Ronald ; Dalebout, Tim J ; Myeni, Sebenzile K ; Kikkert, Marjolein ; Snijder, Eric J ; Li, Zhenfeng ; Barouch, Dan H ; Vellinga Jort ; Johannes Pm Langedijk ; Zahn, Roland C ; Custers, Jerome ; Schuitemaker, Hanneke
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-07
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ArticlesFull Text
Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection aft...
Author / Creator:Joan Em Van Der Lubbe ; Rosendahl Huber, Sietske K ; Vijayan, Aneesh ; Dekking, Liesbeth ; Ella Van Huizen ; Vreugdenhil, Jessica ; Choi, Ying ; Baert, Miranda Rm ; Feddes-De Boer, Karin ; Ana Izquierdo Gil ; Marjolein Van Heerden ; Dalebout, Tim J ; Myeni, Sebenzile K ; Kikkert, Marjolein ; Snijder, Eric J ; Leon De Waal ; Stittelaar, Koert J ; Tolboom, Jeroen Tbm ; Serroyen, Jan ; Muchene, Leacky ; Van Der Fits, Leslie ; Rutten, Lucy ; Johannes Pm Langedijk ; Barouch, Dan H ; Schuitemaker, Hanneke ; Zahn, Roland C ; Wegmann, Frank
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-01
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Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques
Author / Creator:Solforosi, Laura ; Kuipers, Harmjan ; Rosendahl Huber, Sietske K ; Joan Em Van Der Lubbe ; Dekking, Liesbeth ; Czapska-Casey, Dominika N ; Ana Izquierdo Gil ; Baert, Miranda Rm ; Drijver, Joke ; Vaneman, Joost ; Ella Van Huizen ; Choi, Ying ; Vreugdenhil, Jessica ; Kroos, Sanne ; De Wilde, Adriaan H ; Kourkouta, Eleni ; Custers, Jerome ; Dalebout, Tim J ; Myeni, Sebenzile K ; Kikkert, Marjolein ; Snijder, Eric J ; Barouch, Dan H ; Böszörményi, Kinga P ; Stammes, Marieke A ; Kondova, Ivanela ; Verschoor, Ernst J ; Verstrepen, Babs E ; Koopman, Gerrit ; Mooij, Petra ; Bogers, Willy Mjm ; Marjolein Van Heerden ; Muchene, Leacky ; Tolboom, Jeroen Tbm ; Roozendaal, Ramon ; Schuitemaker, Hanneke ; Wegmann, Frank ; Zahn, Roland C
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-01
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ArticlesPeer ReviewedFull Text
SipB-SipC Complex Is Essential for Translocon Formation. e60499
Author / Creator:Myeni, Sebenzile K ; Wang, Lu ; Zhou, Daoguo
Journal title:PloS one, 2013-03, Vol.8 (3)
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ReportsFull Text
Protection of K18-hACE2 Mice against SARS-CoV-2 Challenge by a Capsid Virus-like Particle-Based Vaccine
Author / Creator:Myeni, Sebenzile K ; Leijs, Anouk A ; Bredenbeek, Peter J ; Morales, Shessy Torres ; Linger, Marissa E ; Fougeroux, Cyrielle ; van Zanen-Gerhardt, Sophie ; Zander, Serge A. L ; Sander, Adam F ; Kikkert, Marjolein
Publisher:MDPI AG
Journal title:Vaccines, 2024, Vol.12 (7)
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Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

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Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase

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SipB-SipC complex is essential for translocon formation

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Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity

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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo

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The Main Protease of Middle East Respiratory Syndrome Coronavirus Induces Cleavage of Mitochondrial Antiviral Signaling Protein to Antagonize the Innate Immune Response

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Protection of K18-hACE2 Mice against SARS-CoV-2 Challenge by a Capsid Virus-like Particle-Based Vaccine

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A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses

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HCoV-229E Mpro Suppresses RLR-Mediated Innate Immune Signalling Through Cleavage of NEMO and Through Other Mechanisms

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A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

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Humoral response to SARS-CoV-2 infection among liver transplant recipients

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Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

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Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

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A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies

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Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance

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Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

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Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection aft...

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Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques

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SipB-SipC Complex Is Essential for Translocon Formation. e60499

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Protection of K18-hACE2 Mice against SARS-CoV-2 Challenge by a Capsid Virus-like Particle-Based Vaccine

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