A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2...
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection
About this item
Full title
Author / Creator
Pardieck, Iris N. , van der Sluis, Tetje C. , van der Gracht, Esmé T. I. , Veerkamp, Dominique M. B. , Behr, Felix M. , van Duikeren, Suzanne , Beyrend, Guillaume , Rip, Jasper , Nadafi, Reza , Beyranvand Nejad, Elham , Mülling, Nils , Brasem, Dena J. , Camps, Marcel G. M. , Myeni, Sebenzile K. , Bredenbeek, Peter J. , Kikkert, Marjolein , Kim, Yeonsu , Cicin-Sain, Luka , Abdelaal, Tamim , van Gisbergen, Klaas P. J. M. , Franken, Kees L. M. C. , Drijfhout, Jan Wouter , Melief, Cornelis J. M. , Zondag, Gerben C. M. , Ossendorp, Ferry and Arens, Ramon
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Understanding the mechanisms and impact of booster vaccinations are essential in the design and delivery of vaccination programs. Here we show that a three dose regimen of a synthetic peptide vaccine elicits an accruing CD8
+
T cell response against one SARS-CoV-2 Spike epitope. We see protection against lethal SARS-CoV-2 infection in the K18...
Alternative Titles
Full title
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection
Authors, Artists and Contributors
Author / Creator
van der Sluis, Tetje C.
van der Gracht, Esmé T. I.
Veerkamp, Dominique M. B.
Behr, Felix M.
van Duikeren, Suzanne
Beyrend, Guillaume
Rip, Jasper
Nadafi, Reza
Beyranvand Nejad, Elham
Mülling, Nils
Brasem, Dena J.
Camps, Marcel G. M.
Myeni, Sebenzile K.
Bredenbeek, Peter J.
Kikkert, Marjolein
Kim, Yeonsu
Cicin-Sain, Luka
Abdelaal, Tamim
van Gisbergen, Klaas P. J. M.
Franken, Kees L. M. C.
Drijfhout, Jan Wouter
Melief, Cornelis J. M.
Zondag, Gerben C. M.
Ossendorp, Ferry
Arens, Ramon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cd51eadba8a3427fbfa02b68f915520a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd51eadba8a3427fbfa02b68f915520a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31721-6
