CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
One of the ultimate goals of regenerative medicine is the generation of patient-specific organs from pluripotent stem cells (PSCs). Sheep are potential hosts for growing human organs through the technique of blastocyst complementation. We report here the creation of pancreatogenesis-disabled sheep by oocyte microinjection of CRISPR/Cas9 targeting
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Full title
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5727233
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5727233
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-17805-0
