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956 results for Naphthalenes+-+pharmacology

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ArticlesPeer ReviewedFull Text
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
Author / Creator:Formisano, Luigi ; Lu, Yao ; Servetto, Alberto ; Hanker, Ariella B. ; Jansen, Valerie M. ; Bauer, Joshua A. ; Sudhan, Dhivya R. ; Guerrero-Zotano, Angel L. ; Croessmann, Sarah ; Guo, Yan ; Ericsson, Paula Gonzalez ; Lee, Kyung-min ; Nixon, Mellissa J. ; Schwarz, Luis J. ; Sanders, Melinda E. ; Dugger, Teresa C. ; Cruz, Marcelo Rocha ; Behdad, Amir ; Cristofanilli, Massimo ; Bardia, Aditya ; O’Shaughnessy, Joyce ; Nagy, Rebecca J. ; Lanman, Richard B. ; Solovieff, Nadia ; He, Wei ; Miller, Michelle ; Su, Fei ; Shyr, Yu ; Mayer, Ingrid A. ; Balko, Justin M. ; Arteaga, Carlos L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1373-1373, Article 1373
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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity
Author / Creator:Baumgartner, Christina K. ; Ebrahimi-Nik, Hakimeh ; Iracheta-Vellve, Arvin ; Hamel, Keith M. ; Olander, Kira E. ; Davis, Thomas G. R. ; McGuire, Kathleen A. ; Halvorsen, Geoff T. ; Avila, Omar I. ; Patel, Chirag H. ; Kim, Sarah Y. ; Kammula, Ashwin V. ; Muscato, Audrey J. ; Halliwill, Kyle ; Geda, Prasanthi ; Klinge, Kelly L. ; Xiong, Zhaoming ; Duggan, Ryan ; Mu, Liang ; Yeary, Mitchell D. ; Patti, James C. ; Balon, Tyler M. ; Mathew, Rebecca ; Backus, Carey ; Kennedy, Domenick E. ; Chen, Angeline ; Longenecker, Kenton ; Klahn, Joseph T. ; Hrusch, Cara L. ; Krishnan, Navasona ; Hutchins, Charles W. ; Dunning, Jax P. ; Bulic, Marinka ; Tiwari, Payal ; Colvin, Kayla J. ; Chuong, Cun Lan ; Kohnle, Ian C. ; Rees, Matthew G. ; Boghossian, Andrew ; Ronan, Melissa ; Roth, Jennifer A. ; Wu, Meng-Ju ; Suermondt, Juliette S. M. T. ; Knudsen, Nelson H. ; Cheruiyot, Collins K. ; Sen, Debattama R. ; Griffin, Gabriel K. ; Golub, Todd R. ; El-Bardeesy, Nabeel ; Decker, Joshua H. ; Yang, Yi ; Guffroy, Magali ; Fossey, Stacey ; Trusk, Patricia ; Sun, Im-Meng ; Liu, Yue ; Qiu, Wei ; Sun, Qi ; Paddock, Marcia N. ; Farney, Elliot P. ; Matulenko, Mark A. ; Beauregard, Clay ; Frost, Jennifer M. ; Yates, Kathleen B. ; Kym, Philip R. ; Manguso, Robert T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-10, Vol.622 (7984), p.850-862
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Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins
Author / Creator:Park, Sang-Youl ; Fung, Pauline ; Nishimura, Noriyuki ; Jensen, Davin R ; Fujii, Hiroaki ; Zhao, Yang ; Lumba, Shelley ; Santiago, Julia ; Rodrigues, Americo ; Chow, Tsz-fung F ; Alfred, Simon E ; Bonetta, Dario ; Finkelstein, Ruth ; Provart, Nicholas J ; Desveaux, Darrell ; Rodriguez, Pedro L ; McCourt, Peter ; Zhu, Jian-Kang ; Schroeder, Julian I ; Volkman, Brian F ; Cutler, Sean R
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5930), p.1068-1071
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The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm
Author / Creator:Strünker, Timo ; Goodwin, Normann ; Brenker, Christoph ; Kashikar, Nachiket D. ; Weyand, Ingo ; Seifert, Reinhard ; Kaupp, U. Benjamin
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-03, Vol.471 (7338), p.382-386
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ArticlesPeer ReviewedFull Text
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Author / Creator:Le, Anne ; Cooper, Charles R ; Gouw, Arvin M ; Dinavahi, Ramani ; Maitra, Anirban ; Deck, Lorraine M ; Royer, Robert E ; Vander Jagt, David L ; Semenza, Gregg L ; Dang, Chi V
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.2037-2042
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A novel HDAC inhibitor, CG200745, inhibits pancreatic cancer cell growth and overcomes gemcitabine resistance
Author / Creator:Lee, Hee Seung ; Park, Soo Been ; Kim, Sun A ; Kwon, Sool Ki ; Cha, Hyunju ; Lee, Do Young ; Ro, Seonggu ; Cho, Joong Myung ; Song, Si Young
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-01, Vol.7 (1), p.41615-41615, Article 41615
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Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones
Author / Creator:Tsukada, Kento ; Shinki, Shono ; Kaneko, Akiho ; Murakami, Kazuma ; Irie, Kazuhiro ; Murai, Masatoshi ; Miyoshi, Hideto ; Dan, Shingo ; Kawaji, Kumi ; Hayashi, Hironori ; Kodama, Eiichi N. ; Hori, Aki ; Salim, Emil ; Kuraishi, Takayuki ; Hirata, Naoya ; Kanda, Yasunari ; Asai, Teigo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.1830-1830, Article 1830
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ArticlesPeer ReviewedFull Text
Astrocyte signaling controls spike timing–dependent depression at neocortical synapses
Author / Creator:Min, Rogier ; Nevian, Thomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2012-05, Vol.15 (5), p.746-753
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ArticlesPeer ReviewedFull Text
The CatSper channel: a polymodal chemosensor in human sperm
Author / Creator:Brenker, Christoph ; Goodwin, Normann ; Weyand, Ingo ; Kashikar, Nachiket D ; Naruse, Masahiro ; Krähling, Miriam ; Müller, Astrid ; Kaupp, U Benjamin ; Strünker, Timo
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2012-04, Vol.31 (7), p.1654-1665
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Enhancing Endocannabinoid Neurotransmission Augments The Efficacy of Extinction Training and Ameliorates Traumatic Stress-Induced Behavioral Alterations in Rats
Author / Creator:Morena, Maria ; Berardi, Andrea ; Colucci, Paola ; Palmery, Maura ; Trezza, Viviana ; Hill, Matthew N ; Campolongo, Patrizia
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2018-05, Vol.43 (6), p.1284-1296
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Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding si...
Author / Creator:Wang, Guangcheng ; Liu, Wenjing ; Gong, Zipeng ; Huang, Yong ; Li, Yongjun ; Peng, Zhiyun
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.139-144
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Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine
Author / Creator:Scherma, Maria ; Qvist, Johanna S. ; Asok, Arun ; Huang, Shao-shan C. ; Masia, Paolo ; Deidda, Matteo ; Wei, Ya B. ; Soni, Rajesh K. ; Fratta, Walter ; Fadda, Paola ; Kandel, Eric R. ; Kandel, Denise B. ; Melas, Philippe A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (18), p.9991-10002
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A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs
Author / Creator:Neidle, Stephen
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-08, Vol.29 (15), p.3653
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1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies
Author / Creator:Hagras, Mohamed ; Saleh, Marwa A. ; Ezz Eldin, Rogy R. ; Abuelkhir, Abdelrahman A. ; Khidr, Emad Gamil ; El-Husseiny, Ahmed A. ; El-Mahdy, Hesham A. ; Elkaeed, Eslam B. ; Eissa, Ibrahim H.
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.386-402
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PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor
Author / Creator:Loupy, Alexandre ; Ramakrishnan, Suresh Krishna ; Wootla, Bharath ; Chambrey, Régine ; de la Faille, Renaud ; Bourgeois, Soline ; Bruneval, Patrick ; Mandet, Chantal ; Christensen, Erik Ilso ; Faure, Hélène ; Cheval, Lydie ; Laghmani, Kamel ; Collet, Corinne ; Eladari, Dominique ; Dodd, Robert H ; Ruat, Martial ; Houillier, Pascal
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-09, Vol.122 (9), p.3355-3367
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IL-13-induced airway mucus production is attenuated by MAPK13 inhibition
Author / Creator:Alevy, Yael G ; Patel, Anand C ; Romero, Arthur G ; Patel, Dhara A ; Tucker, Jennifer ; Roswit, William T ; Miller, Chantel A ; Heier, Richard F ; Byers, Derek E ; Brett, Tom J ; Holtzman, Michael J
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-12, Vol.122 (12), p.4555-4568
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Toxicological Analysis of the Arylnaphthalene Lignan Justicidin B Using a Caenorhabditis elegans Model
Author / Creator:Sciandrone, Barbara ; Kentsop, Roméo Arago Dougué ; Pensotti, Roberta ; Ottolina, Gianluca ; Mascheretti, Iride ; Mattana, Monica ; Regonesi, Maria Elena
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-12, Vol.29 (23), p.5516
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Combining explainable machine learning, demographic and multi-omic data to inform precision medicine strategies for inflammatory bowel disease
Author / Creator:Gardiner, Laura-Jayne ; Carrieri, Anna Paola ; Bingham, Karen ; Macluskie, Graeme ; Bunton, David ; McNeil, Marian ; Pyzer-Knapp, Edward O
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-02, Vol.17 (2), p.e0263248-e0263248
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Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2
Author / Creator:Lisboa, Sabrina Francesca ; Niraula, Anzela ; Resstel, Leonardo Barbosa ; Guimaraes, Francisco Silveira ; Godbout, Jonathan P ; Sheridan, John F
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2018-08, Vol.43 (9), p.1924-1933
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Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway
Author / Creator:Lan, Tian ; Wu, Yuhan ; Zhang, Yulei ; Li, Shuhan ; Zhu, Zhanpeng ; Wang, Liyan ; Mao, Xueqin ; Li, Ye ; Fan, Cuiqin ; Wang, Wenjing ; Yu, Shu Yan
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2022-05, Vol.19 (1), p.117-117, Article 117
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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

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Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

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The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

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A novel HDAC inhibitor, CG200745, inhibits pancreatic cancer cell growth and overcomes gemcitabine resistance

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Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

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Astrocyte signaling controls spike timing–dependent depression at neocortical synapses

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The CatSper channel: a polymodal chemosensor in human sperm

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Enhancing Endocannabinoid Neurotransmission Augments The Efficacy of Extinction Training and Ameliorates Traumatic Stress-Induced Behavioral Alterations in Rats

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Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding si...

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Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine

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A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs

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1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies

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PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor

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IL-13-induced airway mucus production is attenuated by MAPK13 inhibition

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Toxicological Analysis of the Arylnaphthalene Lignan Justicidin B Using a Caenorhabditis elegans Model

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Combining explainable machine learning, demographic and multi-omic data to inform precision medicine strategies for inflammatory bowel disease

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Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2

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Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway

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