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ArticlesPeer ReviewedFull Text
Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid
Author / Creator:Garcia-Pavia, Pablo ; aus dem Siepen, Fabian ; Donal, Erwan ; Lairez, Olivier ; van der Meer, Peter ; Kristen, Arnt V. ; Mercuri, Michele F. ; Michalon, Aubin ; Frost, Robert J.A. ; Grimm, Jan ; Nitsch, Roger M. ; Hock, Christoph ; Kahr, Peter C. ; Damy, Thibaud
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-07, Vol.389 (3), p.239-250
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Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia
Author / Creator:Ni, Ruiqing ; Nitsch, Roger M
Publisher:Lausanne: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2022-01
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Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system
Author / Creator:Tackenberg, Christian ; Kulic, Luka ; Nitsch, Roger M.
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2020-09, Vol.15 (9), p.e0239584-e0239584
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ArticlesPeer ReviewedFull Text
The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation
Author / Creator:Tackenberg, Christian ; Nitsch, Roger M
Publisher:England: BioMed Central
Journal title:Molecular brain, 2019-03, Vol.12 (1), p.27-4, Article 27
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A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
Author / Creator:Michalon, Aubin ; Hagenbuch, Andreas ; Huy, Christian ; Varela, Evita ; Combaluzier, Benoit ; Damy, Thibaud ; Suhr, Ole B. ; Saraiva, Maria J. ; Hock, Christoph ; Nitsch, Roger M. ; Jan Grimm
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3142-3142, Article 3142
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ArticlesPeer ReviewedFull Text
A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models
Author / Creator:Wirth, Fabian ; Heitz, Fabrice D. ; Seeger, Christine ; Combaluzier, Ioana ; Breu, Karin ; Denroche, Heather C. ; Thevenet, Julien ; Osto, Melania ; Arosio, Paolo ; Kerr-Conte, Julie ; Verchere, C. Bruce ; Pattou, François ; Lutz, Thomas A. ; Donath, Marc Y. ; Hock, Christoph ; Nitsch, Roger M. ; Grimm, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6294-6294, Article 6294
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Complex interplay between brain function and structure during cerebral amyloidosis in APP transgenic mouse strains revealed by multi-parametric MRI comparison
Author / Creator:Grandjean, Joanes ; Derungs, Rebecca ; Kulic, Luka ; Welt, Tobias ; Henkelman, Mark ; Nitsch, Roger M. ; Rudin, Markus
Publisher:United States: Elsevier Inc
Journal title:NeuroImage (Orlando, Fla.), 2016-07, Vol.134, p.1-11
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Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications
Author / Creator:Rust, Ruslan ; Weber, Rebecca Z ; Generali, Melanie ; Kehl, Debora ; Bodenmann, Chantal ; Uhr, Daniela ; Wanner, Debora ; Zürcher, Kathrin J ; Saito, Hirohide ; Hoerstrup, Simon P ; Nitsch, Roger M ; Tackenberg, Christian
Publisher:London: BioMed Central Ltd
Journal title:Journal of translational medicine, 2022-09, Vol.20 (1), p.1-421, Article 421
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Age-, sex-, and pathology-related variability in brain structure and cognition
Author / Creator:Bachmann, Dario ; Buchmann, Andreas ; Studer, Sandro ; Saake, Antje ; Rauen, Katrin ; Zuber, Isabelle ; Gruber, Esmeralda ; Nitsch, Roger M. ; Hock, Christoph ; Gietl, Anton ; Treyer, Valerie
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2023-08, Vol.13 (1), p.278-278, Article 278
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Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease
Author / Creator:Biscaro, Barbara ; Lindvall, Olle ; Tesco, Giuseppina ; Ekdahl, Christine T. ; Nitsch, Roger M.
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Neuro-degenerative diseases, 2012-01, Vol.9 (4), p.187-198
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A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain
Author / Creator:Rust, Ruslan ; Kirabali, Tunahan ; Grönnert, Lisa ; Dogancay, Berre ; Limasale, Yanuar D P ; Meinhardt, Andrea ; Werner, Carsten ; Laviña, Bàrbara ; Kulic, Luka ; Nitsch, Roger M ; Tackenberg, Christian ; Schwab, Martin E
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2020-03, Vol.14, p.244-244
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Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience-a study in exceptional aging
Author / Creator:Treyer, Valerie ; Meyer, Rafael S ; Buchmann, Andreas ; Crameri, Giovanni A G ; Studer, Sandro ; Saake, Antje ; Gruber, Esmeralda ; Unschuld, Paul G ; Nitsch, Roger M ; Hock, Christoph ; Gietl, Anton F
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-02, Vol.16 (2), p.e0247225-e0247225
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ArticlesPeer ReviewedFull Text
Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease
Author / Creator:Cattepoel, Susann ; Hanenberg, Michael ; Kulic, Luka ; Nitsch, Roger M
Publisher:United States: Public Library of Science (PLoS)
Journal title:PloS one, 2011-04, Vol.6 (4), p.e18296
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White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition
Author / Creator:Bachmann, Dario ; von Rickenbach, Bettina ; Buchmann, Andreas ; Hüllner, Martin ; Zuber, Isabelle ; Studer, Sandro ; Saake, Antje ; Rauen, Katrin ; Gruber, Esmeralda ; Nitsch, Roger M ; Hock, Christoph ; Treyer, Valerie ; Gietl, Anton
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2024-04, Vol.16 (1), p.67-14, Article 67
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The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease
Author / Creator:Kirabali, Tunahan ; Rigotti, Serena ; Siccoli, Alessandro ; Liebsch, Filip ; Shobo, Adeola ; Hock, Christoph ; Nitsch, Roger M ; Multhaup, Gerhard ; Kulic, Luka
Publisher:England: BioMed Central
Journal title:Acta neuropathologica communications, 2019-12, Vol.7 (1), p.194-194, Article 194
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Common Genetic Variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and Late-Onset Alzheimer's Disease
Author / Creator:De Ferrari, Giancarlo V. ; Papassotiropoulos, Andreas ; Biechele, Travis ; De-Vrieze, Fabienne Wavrant ; Avila, Miguel E. ; Major, Michael B. ; Myers, Amanda ; Sáez, Katia ; Henríquez, Juan P. ; Zhao, Alice ; Wollmer, M. Axel ; Nitsch, Roger M. ; Hock, Christoph ; Morris, Chris M. ; Hardy, John ; Moon, Randall T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (22), p.9434-9439
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Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4
Author / Creator:Quevenco, Frances C ; van Bergen, Jiri M ; Treyer, Valerie ; Studer, Sandro T ; Kagerer, Sonja M ; Meyer, Rafael ; Gietl, Anton F ; Kaufmann, Philipp A ; Nitsch, Roger M ; Hock, Christoph ; Unschuld, Paul G
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2020-03, Vol.12, p.46-46
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Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients
Author / Creator:Kälin, Andrea M ; Park, Min T M ; Chakravarty, M Mallar ; Lerch, Jason P ; Michels, Lars ; Schroeder, Clemens ; Broicher, Sarah D ; Kollias, Spyros ; Nitsch, Roger M ; Gietl, Anton F ; Unschuld, Paul G ; Hock, Christoph ; Leh, Sandra E
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2017-03, Vol.9, p.38-38
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Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences
Author / Creator:Bachmann, Dario ; Buchmann, Andreas ; Studer, Sandro ; Saake, Antje ; Rauen, Katrin ; Gruber, Esmeralda ; Nitsch, Roger M. ; Hock, Christoph ; Gietl, Anton ; Treyer, Valerie
Publisher:United States: Wiley
Journal title:Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2024-01, Vol.16 (1), p.e12565-n/a
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Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging
Author / Creator:Klohs, Jan ; Politano, Igna Wojtyna ; Deistung, Andreas ; Grandjean, Joanes ; Drewek, Anna ; Dominietto, Marco ; Keist, Ruth ; Schweser, Ferdinand ; Reichenbach, Jürgen R ; Nitsch, Roger M ; Knuesel, Irene ; Rudin, Markus
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e66097-e66097
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Showing 1 to 20 of 130 results

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Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid

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Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia

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Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system

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The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation

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A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

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A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

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Complex interplay between brain function and structure during cerebral amyloidosis in APP transgenic mouse strains revealed by multi-parametric MRI comparison

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Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

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Age-, sex-, and pathology-related variability in brain structure and cognition

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Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease

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A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

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Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience-a study in exceptional aging

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Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease

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White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition

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The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease

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Common Genetic Variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and Late-Onset Alzheimer's Disease

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Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4

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Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients

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Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences

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Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging

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