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341 results for Nucleus+Pulposus+-+metabolism

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ArticlesPeer ReviewedFull Text
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice
Author / Creator:Novais, Emanuel J. ; Tran, Victoria A. ; Johnston, Shira N. ; Darris, Kayla R. ; Roupas, Alex J. ; Sessions, Garrett A. ; Shapiro, Irving M. ; Diekman, Brian O. ; Risbud, Makarand V.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5213-17, Article 5213
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MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology
Author / Creator:Cazzanelli, Petra ; Wuertz-Kozak, Karin
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-05, Vol.21 (10), p.3601
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Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein
Author / Creator:Cheng, Xiaofei ; Zhang, Liang ; Zhang, Kai ; Zhang, Guoying ; Hu, Ying ; Sun, Xiaojiang ; Zhao, Changqing ; Li, Hua ; Li, Yan Michael ; Zhao, Jie
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2018-05, Vol.77 (5), p.770-779
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Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration
Author / Creator:Zhao, Kangcheng ; An, Ran ; Xiang, Qian ; Li, Gaocai ; Wang, Kun ; Song, Yu ; Liao, Zhiwei ; Li, Shuai ; Hua, Wenbin ; Feng, Xiaobo ; Wu, Xinghuo ; Zhang, Yukun ; Das, Abhirup ; Yang, Cao
Publisher:England: John Wiley & Sons, Inc
Journal title:Cell proliferation, 2021-01, Vol.54 (1), p.e12941-n/a
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Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration
Author / Creator:Cherif, Hosni ; Mannarino, Matthew ; Pacis, Alain Sarabia ; Ragoussis, Jiannis ; Rabau, Oded ; Ouellet, Jean A. ; Haglund, Lisbet
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-04, Vol.23 (7), p.3993
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Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous
Author / Creator:Shi, Sheng ; Kang, Xing-Jian ; Zhou, Zhi ; He, Zhi-Min ; Zheng, Shuang ; He, Shi-Sheng
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2022-05, Vol.24 (1), p.119-119, Article 119
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Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration
Author / Creator:Xing, Hongyuan ; Zhang, Zengjie ; Mao, Qijiang ; Wang, Chenggui ; Zhou, Youlong ; Zhou, Xiaopeng ; Ying, Liwei ; Xu, Haibin ; Hu, Shaojun ; Zhang, Ning
Publisher:England: BioMed Central Ltd
Journal title:Journal of nanobiotechnology, 2021-09, Vol.19 (1), p.264-264, Article 264
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Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3
Author / Creator:Yuan, Xiaoqiu ; Li, Tiefeng ; Shi, Lei ; Miao, Jinhao ; Guo, Yongfei ; Chen, Yu
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2021-08, Vol.27 (1), p.91-91, Article 91
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Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration
Author / Creator:Tang, Zehan ; Hu, Bo ; Zang, Fazhi ; Wang, Jianxi ; Zhang, Xingda ; Chen, Huajiang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-07, Vol.10 (7), p.510-12, Article 510
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Single‐Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression
Author / Creator:Tu, Ji ; Li, Wentian ; Yang, Sidong ; Yang, Pengyi ; Yan, Qi ; Wang, Shenyu ; Lai, Kaitao ; Bai, Xupeng ; Wu, Cenhao ; Ding, Wenyuan ; Cooper‐White, Justin ; Diwan, Ashish ; Yang, Cao ; Yang, Huilin ; Zou, Jun
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2022-01, Vol.9 (3), p.e2103631-n/a
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ArticlesPeer ReviewedFull Text
Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation
Author / Creator:Zhao, Yunpeng ; Qiu, Cheng ; Wang, Wenhan ; Peng, Jiangfan ; Cheng, Xiang ; Shangguan, Yangtao ; Xu, Mingyang ; Li, Jiayi ; Qu, Ruize ; Chen, Xiaomin ; Jia, Suyi ; Luo, Dan ; Liu, Long ; Li, Peng ; Guo, Fengjin ; Vasilev, Krasimir ; Liu, Liang ; Hayball, John ; Dong, Shuli ; Pan, Xin ; Li, Yuhua ; Guo, Linlin ; Cheng, Lei ; Li, Weiwei
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (15), p.7015-7033
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Serglycin secreted by late-stage nucleus pulposus cells is a biomarker of intervertebral disc degeneration
Author / Creator:Chen, Fan ; Lei, Linchuan ; Chen, Shunlun ; Zhao, Zhuoyang ; Huang, Yuming ; Jiang, Guowei ; Guo, Xingyu ; Li, Zemin ; Zheng, Zhaomin ; Wang, Jianru
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.47-47, Article 47
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Mitochondrial quality control in intervertebral disc degeneration
Author / Creator:Song, Yu ; Lu, Saideng ; Geng, Wen ; Feng, Xiaobo ; Luo, Rongjin ; Li, Gaocai ; Yang, Cao
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2021, 53(0), , pp.1-10
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Partial reprogramming strategy for intervertebral disc rejuvenation by activating energy switch
Author / Creator:Cheng, Feng ; Wang, Chenggui ; Ji, Yufei ; Yang, Biao ; Shu, Jiawei ; Shi, Kesi ; Wang, Lulu ; Wang, Shaoke ; Zhang, Yuang ; Huang, Xianpeng ; Zhou, Xiaopeng ; Xia, Kaishun ; Liang, Chengzhen ; Chen, Qixin ; Li, Fangcai
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2022-04, Vol.21 (4), p.e13577-n/a
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p300 arrests intervertebral disc degeneration by regulating the FOXO3/Sirt1/Wnt/β‐catenin axis
Author / Creator:Hao, Yingjie ; Ren, Zhinan ; Yu, Lei ; Zhu, Guangduo ; Zhang, Panke ; Zhu, Jian ; Cao, Shuyan
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2022-08, Vol.21 (8), p.e13677-n/a
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Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation
Author / Creator:Chen, Shunlun ; Lei, Linchuan ; Li, Zemin ; Chen, Fan ; Huang, Yuming ; Jiang, Guowei ; Guo, Xingyu ; Zhao, Zhuoyang ; Liu, Hui ; Wang, Hua ; Liu, Caijun ; Zheng, Zhaomin ; Wang, Jianru
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2022, 54(0), , pp.1-13
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Intervertebral Disc Nucleus Repair: Hype or Hope?
Author / Creator:Tendulkar, Gauri ; Chen, Tao ; Ehnert, Sabrina ; Kaps, Hans-Peter ; Nüssler, Andreas K
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-07, Vol.20 (15), p.3622
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Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis
Author / Creator:Yang, Fan ; Zhang, Yanbin ; Liu, Sheng ; Xiao, Jiheng ; He, Yuxin ; Shao, Zengwu ; Zhang, Yuhui ; Cai, Xianyi ; Xiong, Liming
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2022, Vol.2022, p.1-16
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RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death
Author / Creator:Chen, Songfeng ; Lv, Xiao ; Hu, Binwu ; Shao, Zengwu ; Wang, Baichuan ; Ma, Kaige ; Lin, Hui ; Cui, Min
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2017-05, Vol.22 (5), p.626-638
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M1 macrophage-derived exosomes promote intervertebral disc degeneration by enhancing nucleus pulposus cell senescence through LCN2/NF-κB signaling axis
Author / Creator:Fan, Chunyang ; Wang, Wei ; Yu, Zilin ; Wang, Jiale ; Xu, Wei ; Ji, Zhongwei ; He, Wei ; Hua, Di ; Wang, Wentao ; Yao, Linye ; Deng, Yongkang ; Geng, Dechun ; Wu, Xiexing ; Mao, Haiqing
Publisher:England: BMC
Journal title:Journal of nanobiotechnology, 2024-05, Vol.22 (1), p.301-20, Article 301
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Showing 1 to 20 of 341 results

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Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

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MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology

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Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein

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Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

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Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration

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Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous

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Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration

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Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3

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Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration

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Single‐Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression

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Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation

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Serglycin secreted by late-stage nucleus pulposus cells is a biomarker of intervertebral disc degeneration

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Mitochondrial quality control in intervertebral disc degeneration

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Partial reprogramming strategy for intervertebral disc rejuvenation by activating energy switch

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p300 arrests intervertebral disc degeneration by regulating the FOXO3/Sirt1/Wnt/β‐catenin axis

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Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation

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Intervertebral Disc Nucleus Repair: Hype or Hope?

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Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis

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RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death

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M1 macrophage-derived exosomes promote intervertebral disc degeneration by enhancing nucleus pulposus cell senescence through LCN2/NF-κB signaling axis

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