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22 results for Ong,+Swee+Hoe

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ArticlesPeer ReviewedFull Text
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
Author / Creator:Colom, Bartomeu ; Alcolea, Maria P. ; Piedrafita, Gabriel ; Hall, Michael W. J. ; Wabik, Agnieszka ; Dentro, Stefan C. ; Fowler, Joanna C. ; Herms, Albert ; King, Charlotte ; Ong, Swee Hoe ; Sood, Roshan K. ; Gerstung, Moritz ; Martincorena, Inigo ; Hall, Benjamin A. ; Jones, Philip H.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2020-06, Vol.52 (6), p.604-614
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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Author / Creator:Abby, Emilie ; Dentro, Stefan C. ; Hall, Michael W. J. ; Fowler, Joanna C. ; Ong, Swee Hoe ; Sood, Roshan ; Herms, Albert ; Piedrafita, Gabriel ; Abnizova, Irina ; Siebel, Christian W. ; Gerstung, Moritz ; Hall, Benjamin A. ; Jones, Philip H.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2023-02, Vol.55 (2), p.232-245
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p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
Author / Creator:Murai, Kasumi ; Dentro, Stefan ; Ong, Swee Hoe ; Sood, Roshan ; Fernandez-Antoran, David ; Herms, Albert ; Kostiou, Vasiliki ; Abnizova, Irina ; Hall, Benjamin A. ; Gerstung, Moritz ; Jones, Philip H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.6206-17, Article 6206
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Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries
Author / Creator:Ong, Swee Hoe ; Li, Yilong ; Koike-Yusa, Hiroko ; Yusa, Kosuke
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.7384-10, Article 7384
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Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences
Author / Creator:Ong, Swee Hoe ; Kukkillaya, Vinutha Uppoor ; Wilm, Andreas ; Lay, Christophe ; Ho, Eliza Xin Pei ; Low, Louie ; Hibberd, Martin Lloyd ; Nagarajan, Niranjan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e60811-e60811
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Accurate characterization of the IFITM locus using MiSeq and PacBio sequencing shows genetic variation in Galliformes
Author / Creator:Bassano, Irene ; Ong, Swee Hoe ; Lawless, Nathan ; Whitehead, Thomas ; Fife, Mark ; Kellam, Paul
Publisher:England: BioMed Central
Journal title:BMC genomics, 2017-05, Vol.18 (1), p.419-419, Article 419
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Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3
Author / Creator:Bassano, Irene ; Ong, Swee Hoe ; Sanz-Hernandez, Maximo ; Vinkler, Michal ; Kebede, Adebabay ; Hanotte, Olivier ; Onuigbo, Ebele ; Fife, Mark ; Kellam, Paul
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2019-04, Vol.20 (1), p.272-14, Article 272
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Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe
Author / Creator:Blanquart, François ; Wymant, Chris ; Cornelissen, Marion ; Gall, Astrid ; Bakker, Margreet ; Bezemer, Daniela ; Hall, Matthew ; Hillebregt, Mariska ; Ong, Swee Hoe ; Albert, Jan ; Bannert, Norbert ; Fellay, Jacques ; Fransen, Katrien ; Gourlay, Annabelle J. ; Grabowski, M. Kate ; Gunsenheimer-Bartmeyer, Barbara ; Günthard, Huldrych F. ; Kivelä, Pia ; Kouyos, Roger ; Laeyendecker, Oliver ; Liitsola, Kirsi ; Meyer, Laurence ; Porter, Kholoud ; Ristola, Matti ; van Sighem, Ard ; Vanham, Guido ; Berkhout, Ben ; Kellam, Paul ; Reiss, Peter ; Fraser, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-06, Vol.15 (6), p.e2001855-e2001855
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Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver
Author / Creator:Wymant, Chris ; Blanquart, François ; Golubchik, Tanya ; Gall, Astrid ; Bakker, Margreet ; Bezemer, Daniela ; Croucher, Nicholas J ; Hall, Matthew ; Hillebregt, Mariska ; Ong, Swee Hoe ; Ratmann, Oliver ; Albert, Jan ; Bannert, Norbert ; Fellay, Jacques ; Fransen, Katrien ; Gourlay, Annabelle ; Grabowski, M Kate ; Gunsenheimer-Bartmeyer, Barbara ; Günthard, Huldrych F ; Kivelä, Pia ; Kouyos, Roger ; Laeyendecker, Oliver ; Liitsola, Kirsi ; Meyer, Laurence ; Porter, Kholoud ; Ristola, Matti ; van Sighem, Ard ; Berkhout, Ben ; Cornelissen, Marion ; Kellam, Paul ; Reiss, Peter ; Fraser, Christophe
Publisher:England: Oxford University Press
Journal title:Virus evolution, 2018-01, Vol.4 (1), p.vey007
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ArticlesPeer ReviewedFull Text
Correction: Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe
Author / Creator:Blanquart, François ; Wymant, Chris ; Cornelissen, Marion ; Gall, Astrid ; Bakker, Margreet ; Bezemer, Daniela ; Hall, Matthew ; Hillebregt, Mariska ; Ong, Swee Hoe ; Albert, Jan ; Bannert, Norbert ; Fellay, Jacques ; Fransen, Katrien ; Gourlay, Annabelle J. ; Grabowski, M. Kate ; Gunsenheimer-Bartmeyer, Barbara ; Günthard, Huldrych F. ; Kivelä, Pia ; Kouyos, Roger ; Laeyendecker, Oliver ; Liitsola, Kirsi ; Meyer, Laurence ; Porter, Kholoud ; Ristola, Matti ; van Sighem, Ard ; Vanham, Guido ; Berkhout, Ben ; Kellam, Paul ; Reiss, Peter ; Fraser, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-07, Vol.15 (7), p.e1002608-e1002608
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ArticlesPeer ReviewedFull Text
Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity
Author / Creator:Hoang, Long Truong ; Tolfvenstam, Thomas ; Ooi, Eng Eong ; Khor, Chiea Chuen ; Naim, Ahmand Nazri Mohamed ; Ho, Eliza Xin Pei ; Ong, Swee Hoe ; Wertheim, Heiman F. ; Fox, Annette ; Van Vinh Nguyen, Chau ; Nghiem, Ngoc My ; Ha, Tuan Manh ; Thi Ngoc Tran, Anh ; Tambayah, Paul ; Lin, Raymond ; Sangsajja, Chariya ; Manosuthi, Weerawat ; Chuchottaworn, Chareon ; Sansayunh, Piamlarp ; Chotpitayasunondh, Tawee ; Suntarattiwong, Piyarat ; Chokephaibulkit, Kulkanya ; Puthavathana, Pilaipan ; de Jong, Menno D. ; Farrar, Jeremy ; van Doorn, H. Rogier ; Hibberd, Martin Lloyd
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-11, Vol.9 (11), p.e111640-e111640
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ArticlesPeer ReviewedFull Text
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors
Author / Creator:Dunn, Shanade ; Eberlein, Cath ; Yu, Jason ; Gris-Oliver, Albert ; Ong, Swee Hoe ; Yelland, Urs ; Cureton, Natalie ; Staniszewska, Anna ; McEwen, Robert ; Fox, Millie ; Pilling, James ; Hopcroft, Philip ; Coker, Elizabeth A. ; Jaaks, Patricia ; Garnett, Mathew J. ; Isherwood, Beverley ; Serra, Violeta ; Davies, Barry R. ; Barry, Simon T. ; Lynch, James T. ; Yusa, Kosuke
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2022-11, Vol.41 (46), p.5046-5060
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ArticlesPeer ReviewedFull Text
Author Correction: Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries
Author / Creator:Ong, Swee Hoe ; Li, Yilong ; Koike-Yusa, Hiroko ; Yusa, Kosuke
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-04, Vol.8 (1), p.6136-1, Article 6136
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KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements
Author / Creator:Au, Yan Zi ; Gu, Muxin ; De Braekeleer, Etienne ; Gozdecka, Malgorzata ; Aspris, Demetrios ; Tarumoto, Yusuke ; Cooper, Jonathan ; Yu, Jason ; Ong, Swee Hoe ; Chen, Xi ; Tzelepis, Konstantinos ; Huntly, Brian J. P. ; Vassiliou, George ; Yusa, Kosuke
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-04, Vol.35 (4), p.1012-1022
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ArticlesPeer ReviewedFull Text
Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load
Author / Creator:Zhao, Lele ; Wymant, Chris ; Blanquart, François ; Golubchik, Tanya ; Gall, Astrid ; Bakker, Margreet ; Bezemer, Daniela ; Hall, Matthew ; Ong, Swee Hoe ; Albert, Jan ; Bannert, Norbert ; Fellay, Jacques ; Grabowski, M Kate ; Gunsenheimer-Bartmeyer, Barbara ; Günthard, Huldrych F ; Kivelä, Pia ; Kouyos, Roger D ; Laeyendecker, Oliver ; Meyer, Laurence ; Porter, Kholoud ; van Sighem, Ard ; van der Valk, Marc ; Berkhout, Ben ; Kellam, Paul ; Cornelissen, Marion ; Reiss, Peter ; Fraser, Christophe ; Ferretti, Luca
Publisher:UK: Oxford University Press
Journal title:Virus evolution, 2022, Vol.8 (1), p.veac022
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ArticlesPeer ReviewedFull Text
Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity: e111640
Author / Creator:Hoang, Long Truong ; Tolfvenstam, Thomas ; Ooi, Eng Eong ; Khor, Chiea Chuen ; Naim, Ahmand NazriMohamed ; Ho, Eliza XinPei ; Ong, Swee Hoe ; Wertheim, Heiman F ; Fox, Annette ; Nguyen, Chau VanVinh
Journal title:PloS one, 2014-11, Vol.9 (11)
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ArticlesPeer ReviewedFull Text
Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences. e60811
Author / Creator:Ong, Swee Hoe ; Kukkillaya, Vinutha Uppoor ; Wilm, Andreas ; Lay, Christophe ; Ho, Eliza XinPei ; Low, Louie ; Hibberd, Martin Lloyd ; Nagarajan, Niranjan
Journal title:PloS one, 2013-04, Vol.8 (4)
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ArticlesFull Text
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
Author / Creator:Murai, Kasumi ; Dentro, Stefan ; Ong, Swee Hoe ; Sood, Roshan ; Fernandez-Antoran, David ; Herms, Albert ; Kostiou, Vasiliki ; Hall, Benjamin A ; Gerstung, Moritz ; Jones, Philip H
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-02
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ArticlesFull Text
Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth
Author / Creator:Abby, Emilie ; Dentro, Stefan C ; Hall, Michael W J ; Fowler, Joanna C ; Ong, Swee Hoe ; Sood, Roshan ; Siebel, Christian W ; Gerstung, Moritz ; Hall, Benjamin A ; Jones, Philip
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-06
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Precancer: Mutant clones in normal epithelium outcompete and eliminate esophageal micro-tumors
Author / Creator:Colom, Bartomeu ; Herms, Albert ; Dentro, Stefan ; King, Charlotte ; Sood, Roshan ; Alcolea, Maria ; Fernandez-Antoran, David ; Ong, Swee Hoe ; Fowler, Joanna C ; Mahbubani, Krishnaa ; Saeb-Parsy, Kourosh ; Gerstung, Moritz ; Hall, Benjamin A ; Jones, Philip
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-06
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Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium

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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth

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p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition

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Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries

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Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences

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Accurate characterization of the IFITM locus using MiSeq and PacBio sequencing shows genetic variation in Galliformes

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Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3

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Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

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Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver

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Correction: Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

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Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity

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AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors

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Author Correction: Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries

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KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements

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Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load

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Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity: e111640

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Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences. e60811

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p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition

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Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

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Precancer: Mutant clones in normal epithelium outcompete and eliminate esophageal micro-tumors

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