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ArticlesPeer ReviewedFull Text
A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines
Author / Creator:Schneider, Dina ; Xiong, Ying ; Wu, Darong ; Nӧlle, Volker ; Schmitz, Sarah ; Haso, Waleed ; Kaiser, Andrew ; Dropulic, Boro ; Orentas, Rimas J.
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2017-05, Vol.5 (1), p.42-42, Article 42
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Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells
Author / Creator:Paugh, Barbara S. ; Baranyi, Lajos ; Roy, Andre ; He, Hua-Jun ; Harris, Lindsay ; Cole, Kenneth D. ; Artlip, Moria ; Raimund, Caroline ; Langan, Patricia S. ; Jana, Srikanta ; Orentas, Rimas J. ; Lin-Gibson, Sheng ; Krueger, Winfried ; Dropulić, Boro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.389-389, Article 389
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CD19 CAR T cell product and disease attributes predict leukemia remission durability
Author / Creator:Finney, Olivia C. ; Brakke, Hannah ; Rawlings-Rhea, Stephanie ; Hicks, Roxana ; Doolittle, Danielle ; Lopez, Marisa ; Futrell, Ben ; Orentas, Rimas J. ; Li, Daniel ; Gardner, Rebecca ; Jensen, Michael C.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-05, Vol.129 (5), p.2123-2132
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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
Author / Creator:Fry, Terry J ; Shah, Nirali N ; Orentas, Rimas J ; Stetler-Stevenson, Maryalice ; Yuan, Constance M ; Ramakrishna, Sneha ; Wolters, Pamela ; Martin, Staci ; Delbrook, Cindy ; Yates, Bonnie ; Shalabi, Haneen ; Fountaine, Thomas J ; Shern, Jack F ; Majzner, Robbie G ; Stroncek, David F ; Sabatino, Marianna ; Feng, Yang ; Dimitrov, Dimiter S ; Zhang, Ling ; Nguyen, Sang ; Qin, Haiying ; Dropulic, Boro ; Lee, Daniel W ; Mackall, Crystal L
Publisher:New York: Springer New York
Journal title:Nature medicine, 2018-01, Vol.24 (1), p.20-28
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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
Author / Creator:Long, Adrienne H ; Haso, Waleed M ; Shern, Jack F ; Wanhainen, Kelsey M ; Murgai, Meera ; Ingaramo, Maria ; Smith, Jillian P ; Walker, Alec J ; Kohler, M Eric ; Venkateshwara, Vikas R ; Kaplan, Rosandra N ; Patterson, George H ; Fry, Terry J ; Orentas, Rimas J ; Mackall, Crystal L
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-06, Vol.21 (6), p.581-590
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ArticlesPeer ReviewedFull Text
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis
Author / Creator:Vitanza, Nicholas A. ; Johnson, Adam J. ; Wilson, Ashley L. ; Brown, Christopher ; Yokoyama, Jason K. ; Künkele, Annette ; Chang, Cindy A. ; Rawlings-Rhea, Stephanie ; Huang, Wenjun ; Seidel, Kristy ; Albert, Catherine M. ; Pinto, Navin ; Gust, Juliane ; Finn, Laura S. ; Ojemann, Jeffrey G. ; Wright, Jason ; Orentas, Rimas J. ; Baldwin, Michael ; Gardner, Rebecca A. ; Jensen, Michael C. ; Park, Julie R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-09, Vol.27 (9), p.1544-1552
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ArticlesPeer ReviewedFull Text
Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase
Author / Creator:Walker, Alec J. ; Majzner, Robbie G. ; Zhang, Ling ; Wanhainen, Kelsey ; Long, Adrienne H. ; Nguyen, Sang M. ; Lopomo, Paola ; Vigny, Marc ; Fry, Terry J. ; Orentas, Rimas J. ; Mackall, Crystal L.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-09, Vol.25 (9), p.2189-2201
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ArticlesPeer ReviewedFull Text
Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data
Author / Creator:Kohler, M. Eric ; Johnson, Bryon D. ; Palen, Katie ; Chen, Qing‐Rong ; Khan, Javed ; Orentas, Rimas J.
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 2010-11, Vol.101 (11), p.2316-2324
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Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)
Author / Creator:Adair, Jennifer E. ; Androski, Lindsay ; Bayigga, Lois ; Bazira, Deus ; Brandon, Eugene ; Dee, Lynda ; Deeks, Steven ; Draz, Mohamed ; Dubé, Karine ; Dybul, Mark ; Gurkan, Umut ; Harlow, Evelyn ; Kityo, Cissy ; Louella, Michael ; Malik, Punam ; Mathews, Vikram ; McKemey, Adrian ; Mugerwa, Henry ; Muyanja, Daniel ; Olayiwola, Olabimpe ; Orentas, Rimas J. ; Popovski, Alex ; Sheehy, Jeff ; Ssali, Francis ; Nsubuga, Moses Supercharger ; Tisdale, John F. ; Verhoeyen, Els ; Dropulić, Boro
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2023-04, Vol.30 (3-4), p.216-221
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ArticlesPeer ReviewedFull Text
Correction: Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)
Author / Creator:Adair, Jennifer E. ; Androski, Lindsay ; Bayigga, Lois ; Bazira, Deus ; Brandon, Eugene ; Dee, Lynda ; Deeks, Steven ; Draz, Mohamed ; Dubé, Karine ; Dybul, Mark ; Gurkan, Umut ; Harlow, Evelyn ; Kityo, Cissy ; Louella, Michael ; Malik, Punam ; Mathews, Vikram ; McKemey, Adrian ; Mugerwa, Henry ; Muyanja, Daniel ; Olayiwola, Olabimpe ; Orentas, Rimas J. ; Popovski, Alex ; Sheehy, Jeff ; Ssali, Francis ; Nsubuga, Moses Supercharger ; Tisdale, John F. ; Verhoeyen, Els ; Dropulić, Boro
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2023-04, Vol.30 (3-4), p.405-405
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ArticlesPeer ReviewedFull Text
320 CAR-T cell manufacturing from fresh whole blood facilitates point-of-care therapeutic cell production
Author / Creator:Xiong, Ying ; Xie, Yanping ; Liu, Yang ; Addington-Hall, Matthew ; Ferencz, Beatrix ; Luo, Tony ; Yates, Maggie ; Slessareva, Oxana ; Oparaocha, Ibeawuchi ; Zhu, Zhongyu ; Dropuli, Boro ; Orentas, Rimas J
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A364-A364
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ArticlesPeer ReviewedFull Text
Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen
Author / Creator:Zheng, Jin ; Kohler, M Eric ; Chen, Qingrong ; Weber, James ; Khan, Javed ; Johnson, Bryon D ; Orentas, Rimas J
Publisher:England: BioMed Central Ltd
Journal title:BMC immunology, 2007-03, Vol.8 (1), p.4-4, Article 4
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ArticlesPeer ReviewedFull Text
Transduction of Primary Lymphocytes with Epstein-Barr Virus (EBV) Latent Membrane Protein-Specific T-Cell Receptor Induces Lysis of Virus-Infected Cells: A Novel Strategy for the Treatment of Hodgkin'...
Author / Creator:Jurgens, Lisa A. ; Khanna, Rajiv ; Weber, James ; Orentas, Rimas J.
Publisher:Netherlands: Springer Nature B.V
Journal title:Journal of clinical immunology, 2006-01, Vol.26 (1), p.22-32
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Newsletter articlesFull Text
INTERNATIONAL PATENT: LENTIGEN TECHNOLOGY, INC. , ORENTAS, RIMAS J. , SCHNEIDER, DINA , HASO, WALEED M. , MILTENYI, STEFAN , DROPULIC, BORO FILES APPLICATION FOR "COMPOSITIONS AND METHODS FOR TREATING...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation
Author / Creator:James E. K. Hildreth ; Orentas, Rimas J.
Publisher:Washington, DC: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 1989-06, Vol.244 (4908), p.1075-1078
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Induction of CD4$^+$ Human Cytolytic T Cells Specific for HIV-Infected Cells by a gp160 Subunit Vaccine
Author / Creator:Orentas, Rimas J. ; James E. K. Hildreth ; Obah, Eugene ; Polydefkis, Michael ; Smith, Gale E. ; Clements, Mary Lou ; Siliciano, Robert F.
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 1990-06, Vol.248 (4960), p.1234-1237
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ArticlesPeer ReviewedFull Text
Production of Macrophage Migration Inhibitory Factor by Human and Murine Neuroblastoma
Author / Creator:Bin, Qian ; Johnson, Bryon D. ; Schauer, Dennis W. ; Casper, James T. ; Orentas, Rimas J.
Publisher:Basel, Switzerland: Karger
Journal title:Tumor biology, 2002-05, Vol.23 (3), p.123-129
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ArticlesPeer ReviewedFull Text
CD22-CAR T Cells Induce Remissions in CD19-CAR Naïve and Resistant B-ALL
Author / Creator:Fry, Terry J. ; Shah, Nirali N. ; Orentas, Rimas J. ; Stetler-Stevenson, Maryalice ; Yuan, Constance M. ; Ramakrishna, Sneha ; Wolters, Pamela ; Martin, Staci ; Delbrook, Cindy ; Yates, Bonnie ; Shalabi, Haneen ; Fountaine, Thomas J. ; Shern, Jack F. ; Majzner, Robbie G. ; Stroncek, David F. ; Sabatino, Marianna ; Feng, Yang ; Dimitrov, Dimiter S. ; Zhang, Ling ; Nguyen, Sang ; Qin, Haiying ; Dropulic, Boro ; Lee, Daniel W. ; Mackall, Crystal L.
Journal title:Nature medicine, 2017-11, Vol.24 (1), p.20-28
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ArticlesPeer ReviewedFull Text
Enhanced glycolytic metabolism is associated with exhaustion and poor antitumor efficacy in a xenograft model of chimeric antigen receptor T cell therapy for sarcoma
Author / Creator:Long, Adrienne H ; Orentas, Rimas J ; Mackall, Crystal L
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2013-11, Vol.1 (S1), p.P21-P21, Article P21
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ArticlesPeer ReviewedFull Text
ALK (anaplastic lymphoma kinase, CD246)-specific CARs: new immunotherapeutic agents for the treatment of pediatric solid tumors
Author / Creator:Orentas, Rimas J ; Lopomo, Paola ; Babbitt, William ; Vigny, Marc ; Mackall, Crystal L
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2013-11, Vol.1 (S1), p.P27-P27, Article P27
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Showing 1 to 20 of 22 results

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A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines

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Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells

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CD19 CAR T cell product and disease attributes predict leukemia remission durability

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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

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Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

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Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

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Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data

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Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)

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Correction: Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)

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320 CAR-T cell manufacturing from fresh whole blood facilitates point-of-care therapeutic cell production

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Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen

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Transduction of Primary Lymphocytes with Epstein-Barr Virus (EBV) Latent Membrane Protein-Specific T-Cell Receptor Induces Lysis of Virus-Infected Cells: A Novel Strategy for the Treatment of Hodgkin'...

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INTERNATIONAL PATENT: LENTIGEN TECHNOLOGY, INC. , ORENTAS, RIMAS J. , SCHNEIDER, DINA , HASO, WALEED M. , MILTENYI, STEFAN , DROPULIC, BORO FILES APPLICATION FOR "COMPOSITIONS AND METHODS FOR TREATING...

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Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation

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Induction of CD4$^+$ Human Cytolytic T Cells Specific for HIV-Infected Cells by a gp160 Subunit Vaccine

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Production of Macrophage Migration Inhibitory Factor by Human and Murine Neuroblastoma

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CD22-CAR T Cells Induce Remissions in CD19-CAR Naïve and Resistant B-ALL

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Enhanced glycolytic metabolism is associated with exhaustion and poor antitumor efficacy in a xenograft model of chimeric antigen receptor T cell therapy for sarcoma

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ALK (anaplastic lymphoma kinase, CD246)-specific CARs: new immunotherapeutic agents for the treatment of pediatric solid tumors

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