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ArticlesFull Text
Osimertinib
Author / Creator:Li, Shaorong ; Wang, Jia ; Wang, Nannan ; Yu, Jinming ; Xing, Ligang ; Zhu, Lifang ; Liu, Changting ; Meng, Xiangjiao ; Yang, Zhenfan ; Wang, Linlin ; Zheng, Li
Publisher:Spandidos Publications
Journal title:Oncology reports, 2019-01, Vol.41 (1), p.77
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ArticlesPeer ReviewedFull Text
Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer
Author / Creator:Wu, Yi-Long ; Tsuboi, Masahiro ; He, Jie ; John, Thomas ; Grohe, Christian ; Majem, Margarita ; Goldman, Jonathan W ; Laktionov, Konstantin ; Kim, Sang-We ; Kato, Terufumi ; Vu, Huu-Vinh ; Lu, Shun ; Lee, Kye-Young ; Akewanlop, Charuwan ; Yu, Chong-Jen ; de Marinis, Filippo ; Bonanno, Laura ; Domine, Manuel ; Shepherd, Frances A ; Zeng, Lingmin ; Hodge, Rachel ; Atasoy, Ajlan ; Rukazenkov, Yuri ; Herbst, Roy S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-10, Vol.383 (18), p.1711-1723
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Osimertinib
Publisher:Oxford University Press
Journal title:American journal of health-system pharmacy, 2015-12, Vol.72 (24), p.2126
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Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer
Author / Creator:Soria, Jean-Charles ; Ohe, Yuichiro ; Vansteenkiste, Johan ; Reungwetwattana, Thanyanan ; Chewaskulyong, Busyamas ; Lee, Ki Hyeong ; Dechaphunkul, Arunee ; Imamura, Fumio ; Nogami, Naoyuki ; Kurata, Takayasu ; Okamoto, Isamu ; Zhou, Caicun ; Cho, Byoung Chul ; Cheng, Ying ; Cho, Eun Kyung ; Voon, Pei Jye ; Planchard, David ; Su, Wu-Chou ; Gray, Jhanelle E ; Lee, Siow-Ming ; Hodge, Rachel ; Marotti, Marcelo ; Rukazenkov, Yuri ; Ramalingam, Suresh S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-01, Vol.378 (2), p.113-125
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Osimertinib: First Global Approval
Author / Creator:Greig, Sarah L.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2016-02, Vol.76 (2), p.263-273
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Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
Author / Creator:Ramalingam, Suresh S ; Vansteenkiste, Johan ; Planchard, David ; Cho, Byoung Chul ; Gray, Jhanelle E ; Ohe, Yuichiro ; Zhou, Caicun ; Reungwetwattana, Thanyanan ; Cheng, Ying ; Chewaskulyong, Busyamas ; Shah, Riyaz ; Cobo, Manuel ; Lee, Ki Hyeong ; Cheema, Parneet ; Tiseo, Marcello ; John, Thomas ; Lin, Meng-Chih ; Imamura, Fumio ; Kurata, Takayasu ; Todd, Alexander ; Hodge, Rachel ; Saggese, Matilde ; Rukazenkov, Yuri ; Soria, Jean-Charles
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-01, Vol.382 (1), p.41-50
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Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC
Author / Creator:Tsuboi, Masahiro ; Herbst, Roy S. ; John, Thomas ; Kato, Terufumi ; Majem, Margarita ; Grohé, Christian ; Wang, Jie ; Goldman, Jonathan W. ; Lu, Shun ; Su, Wu-Chou ; de Marinis, Filippo ; Shepherd, Frances A. ; Lee, Ki Hyeong ; Le, Nhieu Thi ; Dechaphunkul, Arunee ; Kowalski, Dariusz ; Poole, Lynne ; Bolanos, Ana ; Rukazenkov, Yuri ; Wu, Yi-Long
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-07, Vol.389 (2), p.137-147
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Osimertinib with or without Chemotherapy in EGFR -Mutated Advanced NSCLC
Author / Creator:Planchard, David ; Jänne, Pasi A ; Cheng, Ying ; Yang, James C-H ; Yanagitani, Noriko ; Kim, Sang-We ; Sugawara, Shunichi ; Yu, Yan ; Fan, Yun ; Geater, Sarayut L ; Laktionov, Konstantin ; Lee, Chee K ; Valdiviezo, Natalia ; Ahmed, Samreen ; Maurel, Jean-Marc ; Andrasina, Igor ; Goldman, Jonathan ; Ghiorghiu, Dana ; Rukazenkov, Yuri ; Todd, Alex ; Kobayashi, Kunihiko
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-11, Vol.389 (21), p.1935-1948
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Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
Author / Creator:Mok, Tony S ; Wu, Yi-Long ; Ahn, Myung-Ju ; Garassino, Marina C ; Kim, Hye R ; Ramalingam, Suresh S ; Shepherd, Frances A ; He, Yong ; Akamatsu, Hiroaki ; Theelen, Willemijn S.M.E ; Lee, Chee K ; Sebastian, Martin ; Templeton, Alison ; Mann, Helen ; Marotti, Marcelo ; Ghiorghiu, Serban ; Papadimitrakopoulou, Vassiliki A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-02, Vol.376 (7), p.629-640
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Osimertinib in Stage III EGFR-Mutated NSCLC — Game, Set, Match
Author / Creator:Leighl, Natasha B.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-08, Vol.391 (7), p.652-654
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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase...
Author / Creator:Wu, Yi-Long, Prof ; Guarneri, Valentina, Prof ; Voon, Pei Jye, MD ; Lim, Boon Khaw, MRCP ; Yang, Jin-Ji, Prof ; Wislez, Marie, Prof ; Huang, Cheng, Prof ; Liam, Chong Kin, Prof ; Mazieres, Julien, Prof ; Tho, Lye Mun, PhD ; Hayashi, Hidetoshi, Prof ; Nhung, Nguyen Viet, PhD ; Chia, Puey Ling, PhD ; de Marinis, Filippo, Prof ; Raskin, Jo, MD ; Zhou, Qinghua, Prof ; Finocchiaro, Giovanna, MD ; Le, Anh Tuan, PhD ; Wang, Jialei, Prof ; Dooms, Christophe, PhD ; Kato, Terufumi, PhD ; Nadal, Ernest, PhD ; Hin, How Soon, Prof ; Smit, Egbert F, Prof ; Wermke, Martin, Prof ; Tan, Daniel, PhD ; Morise, Masahiro, PhD ; O'Brate, Aurora, PhD ; Adrian, Svenja, MD ; Pfeiffer, Boris M, MD ; Stroh, Christopher, PhD ; Juraeva, Dilafruz, PhD ; Strotmann, Rainer, MD ; Goteti, Kosalaram, MD ; Berghoff, Karin, MD ; Ellers-Lenz, Barbara, MSc ; Karachaliou, Niki, MD ; Le, Xiuning, MD ; Kim, Tae Min, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-08, Vol.25 (8), p.989-1002
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Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC
Author / Creator:Lu, Shun ; Kato, Terufumi ; Dong, Xiaorong ; Ahn, Myung-Ju ; Quang, Le-Van ; Soparattanapaisarn, Nopadol ; Inoue, Takako ; Wang, Chih-Liang ; Huang, Meijuan ; Yang, James Chih-Hsin ; Cobo, Manuel ; Özgüroğlu, Mustafa ; Casarini, Ignacio ; Khiem, Dang-Van ; Sriuranpong, Virote ; Cronemberger, Eduardo ; Takahashi, Toshiaki ; Runglodvatana, Yotsawaj ; Chen, Ming ; Huang, Xiangning ; Grainger, Ellie ; Ghiorghiu, Dana ; van der Gronde, Toon ; Ramalingam, Suresh S.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-08, Vol.391 (7), p.585-597
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Notch pathway regulates osimertinib drug‐tolerant persistence in EGFR‐mutated non–small‐cell lung cancer
Author / Creator:Takahashi, Hirofumi ; Sakakibara‐Konishi, Jun ; Furuta, Megumi ; Shoji, Tetsuaki ; Tsuji, Kosuke ; Morinaga, Daisuke ; Kikuchi, Eiki ; Kikuchi, Junko ; Noguchi, Takuro ; Hatanaka, Kanako C. ; Hatanaka, Yutaka ; Shinagawa, Naofumi ; Konno, Satoshi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2023-04, Vol.114 (4), p.1635-1650
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Adjuvant Osimertinib in EGFR-Mutated Non–Small-Cell Lung Cancer
Author / Creator:Planchard, David
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-10, Vol.383 (18), p.1780-1782
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Trametinib overcomes KRAS‐G12V–induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR‐mutant lung cancer
Author / Creator:Fukuda, Koji ; Otani, Sakiko ; Takeuchi, Shinji ; Arai, Sachiko ; Nanjo, Shigeki ; Tanimoto, Azusa ; Nishiyama, Akihiro ; Naoki, Katsuhiko ; Yano, Seiji
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-09, Vol.112 (9), p.3784-3795
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MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer
Author / Creator:Yan, Dan ; Huelse, Justus M ; Kireev, Dmitri ; Tan, Zikang ; Chen, Luxiao ; Goyal, Subir ; Wang, Xiaodong ; Frye, Stephen V ; Behera, Madhusmita ; Schneider, Frank ; Ramalingam, Suresh S ; Owonikoko, Taofeek ; Earp, H Shelton ; DeRyckere, Deborah ; Graham, Douglas K
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-08, Vol.132 (15)
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Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer
Author / Creator:Leonetti, Alessandro ; Sharma, Sugandhi ; Minari, Roberta ; Perego, Paola ; Giovannetti, Elisa ; Tiseo, Marcello
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2019-10, Vol.121 (9), p.725-737
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Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre...
Author / Creator:Sequist, Lecia V, MD ; Han, Ji-Youn, Prof ; Ahn, Myung-Ju, Prof ; Cho, Byoung Chul, MD ; Yu, Helena, MD ; Kim, Sang-We, Prof ; Yang, James Chih-Hsin, Prof ; Lee, Jong Seok, MD ; Su, Wu-Chou, MD ; Kowalski, Dariusz, MD ; Orlov, Sergey, PhD ; Cantarini, Mireille, MD ; Verheijen, Remy B, PhD ; Mellemgaard, Anders, MD ; Ottesen, Lone, MD ; Frewer, Paul, MSc ; Ou, Xiaoling, PhD ; Oxnard, Geoffrey, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-03, Vol.21 (3), p.373-386
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Survival benefit of combinatorial osimertinib rechallenge and entrectinib in an EGFR‐mutant NSCLC patient with acquired LMNA‐NTRK1 fusion following osimertinib resistance
Author / Creator:Wang, Jiao‐Li ; Wang, Liu‐sheng ; Zhu, Jun‐qi ; Ren, Jie ; Wang, Di ; Luo, Man
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:Respirology case reports, 2022-11, Vol.10 (11), p.e01054-n/a
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Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction
Author / Creator:Han, Rui ; Hao, Shuai ; Lu, Conghua ; Zhang, Chong ; Lin, Caiyu ; Li, Li ; Wang, Yubo ; Hu, Chen ; He, Yong
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2020-06, Vol.14 (6), p.1152-1169
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Osimertinib

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Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer

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Osimertinib

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Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer

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Osimertinib: First Global Approval

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Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC

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Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC

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Osimertinib with or without Chemotherapy in EGFR -Mutated Advanced NSCLC

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Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer

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Osimertinib in Stage III EGFR-Mutated NSCLC — Game, Set, Match

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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase...

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Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC

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Notch pathway regulates osimertinib drug‐tolerant persistence in EGFR‐mutated non–small‐cell lung cancer

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Adjuvant Osimertinib in EGFR-Mutated Non–Small-Cell Lung Cancer

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Trametinib overcomes KRAS‐G12V–induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR‐mutant lung cancer

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MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer

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Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer

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Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre...

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Survival benefit of combinatorial osimertinib rechallenge and entrectinib in an EGFR‐mutant NSCLC patient with acquired LMNA‐NTRK1 fusion following osimertinib resistance

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Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction

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