Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
About this item
Full title
Author / Creator
FLAURA Investigators , Ramalingam, Suresh S , Vansteenkiste, Johan , Planchard, David , Cho, Byoung Chul , Gray, Jhanelle E , Ohe, Yuichiro , Zhou, Caicun , Reungwetwattana, Thanyanan , Cheng, Ying , Chewaskulyong, Busyamas , Shah, Riyaz , Cobo, Manuel , Lee, Ki Hyeong , Cheema, Parneet , Tiseo, Marcello , John, Thomas , Lin, Meng-Chih , Imamura, Fumio , Kurata, Takayasu , Todd, Alexander , Hodge, Rachel , Saggese, Matilde , Rukazenkov, Yuri and Soria, Jean-Charles
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Osimertinib was compared with standard EGFR blockers among patients with non–small-cell lung cancer with activating mutations in
EGFR
. The median overall survival was 38.6 months with osimertinib and 31.8 months with erlotinib or gefitinib. This 20% lower risk of death was noted despite the crossover of patients from standard therapy to osim...
Alternative Titles
Full title
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
Authors, Artists and Contributors
Author / Creator
Ramalingam, Suresh S
Vansteenkiste, Johan
Planchard, David
Cho, Byoung Chul
Gray, Jhanelle E
Ohe, Yuichiro
Zhou, Caicun
Reungwetwattana, Thanyanan
Cheng, Ying
Chewaskulyong, Busyamas
Shah, Riyaz
Cobo, Manuel
Lee, Ki Hyeong
Cheema, Parneet
Tiseo, Marcello
John, Thomas
Lin, Meng-Chih
Imamura, Fumio
Kurata, Takayasu
Todd, Alexander
Hodge, Rachel
Saggese, Matilde
Rukazenkov, Yuri
Soria, Jean-Charles
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2331832278
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331832278
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1913662
