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ArticlesPeer ReviewedFull Text
Mechanisms of pruritus in cholestasis: understanding and treating the itch
Author / Creator:Beuers, Ulrich ; Wolters, Frank ; Oude Elferink, Ronald P. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2023-01, Vol.20 (1), p.26-36
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Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP
Author / Creator:Donkers, Joanne M. ; Zehnder, Benno ; van Westen, Gerard J. P. ; Kwakkenbos, Mark J. ; IJzerman, Adriaan P. ; Oude Elferink, Ronald P. J. ; Beuers, Ulrich ; Urban, Stephan ; van de Graaf, Stan F. J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-11, Vol.7 (1), p.15307-13, Article 15307
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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling
Author / Creator:Keune, Willem-Jan ; Hausmann, Jens ; Bolier, Ruth ; Tolenaars, Dagmar ; Kremer, Andreas ; Heidebrecht, Tatjana ; Joosten, Robbie P. ; Sunkara, Manjula ; Morris, Andrew J. ; Matas-Rico, Elisa ; Moolenaar, Wouter H. ; Oude Elferink, Ronald P. ; Perrakis, Anastassis
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11248-11248, Article 11248
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ArticlesPeer ReviewedFull Text
Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)
Author / Creator:Oude Elferink, Ronald P J ; Paulusma, Coen C
Publisher:Germany: Springer Nature B.V
Journal title:Pflügers Archiv, 2007-02, Vol.453 (5), p.601-610
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Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions
Author / Creator:ter Riet, Gerben ; Korevaar, Daniel A ; Leenaars, Marlies ; Sterk, Peter J ; Van Noorden, Cornelis J F ; Bouter, Lex M ; Lutter, René ; Elferink, Ronald P Oude ; Hooft, Lotty
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e43404-e43404
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Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4
Author / Creator:van der Mark, Vincent A. ; Ghiboub, Mohammed ; Marsman, Casper ; Zhao, Jing ; van Dijk, Remco ; Hiralall, Johan K. ; Ho-Mok, Kam S. ; Castricum, Zoë ; de Jonge, Wouter J. ; Oude Elferink, Ronald P. J. ; Paulusma, Coen C.
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2017-02, Vol.74 (4), p.715-730
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ArticlesPeer ReviewedFull Text
Glyco-conjugated bile acids drive the initial metaplastic gland formation from multi-layered glands through crypt-fission in a murine model
Author / Creator:Straub, Danielle ; Oude Elferink, Ronald P J ; Jansen, Peter L M ; Bergman, Jacques J G H M ; Parikh, Kaushal ; Krishnadath, Kausilia K
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-07, Vol.14 (7), p.e0220050-e0220050
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ArticlesPeer ReviewedFull Text
Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease—A Comprehensive Review
Author / Creator:Maroni, Luca ; van de Graaf, Stan F. J. ; Hohenester, Simon D. ; Oude Elferink, Ronald P. J. ; Beuers, Ulrich
Publisher:Boston: Springer US
Journal title:Clinical reviews in allergy & immunology, 2015-06, Vol.48 (2-3), p.182-191
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A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines
Author / Creator:Adam, Aziza A A ; van der Mark, Vincent A ; Donkers, Joanne M ; Wildenberg, Manon E ; Oude Elferink, Ronald P J ; Chamuleau, Robert A F M ; Hoekstra, Ruurdtje
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-04, Vol.13 (4), p.e0193664-e0193664
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IgG4-Associated Cholangitis: A Comprehensive Review
Author / Creator:Hubers, Lowiek M. ; Maillette de Buy Wenniger, Lucas J. ; Doorenspleet, Marieke E. ; Klarenbeek, Paul L. ; Verheij, Joanne ; Rauws, Erik A. ; van Gulik, Thomas M. ; Oude Elferink, Ronald P. J. ; van de Graaf, Stan F. J. ; de Vries, Niek ; Beuers, Ulrich
Publisher:Boston: Springer US
Journal title:Clinical reviews in allergy & immunology, 2015-06, Vol.48 (2-3), p.198-206
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ArticlesPeer ReviewedFull Text
Primary biliary cirrhosis
Author / Creator:Hohenester, Simon ; Oude-Elferink, Ronald P. J. ; Beuers, Ulrich
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Seminars in immunopathology, 2009-09, Vol.31 (3), p.283-307
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ArticlesPeer ReviewedFull Text
ATP8B1 is essential for maintaining normal hearing
Author / Creator:Stapelbroek, Janneke M ; Peters, Theo A ; van Beurden, Denis H.A ; Curfs, Jo H.A.J ; Joosten, Anneke ; Beynon, Andy J ; van Leeuwen, Bibian M ; van der Velden, Lieke M ; Bull, Laura ; Oude Elferink, Ronald P ; van Zanten, Bert A ; Klomp, Leo W.J ; Houwen, Roderick H.J
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9709-9714
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ArticlesPeer ReviewedFull Text
Liver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failure
Author / Creator:Nibourg, Geert A A ; Chamuleau, Robert A F M ; van der Hoeven, Tessa V ; Maas, Martinus A W ; Ruiter, An F C ; Lamers, Wouter H ; Oude Elferink, Ronald P J ; van Gulik, Thomas M ; Hoekstra, Ruurdtje
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-06, Vol.7 (6), p.e38778-e38778
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ArticlesPeer ReviewedFull Text
Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial
Author / Creator:Bolier, Ruth ; de Vries, Elsemieke S ; Parés, Albert ; Helder, Jeltje ; Kemper, E Marleen ; Zwinderman, Koos ; Elferink, Ronald P Oude ; Beuers, Ulrich
Publisher:England: BioMed Central Ltd
Journal title:Current controlled trials in cardiovascular medicine, 2017-05, Vol.18 (1), p.230-9, Article 230
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ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells
Author / Creator:Gómez-Mellado, Valentina E. ; Chang, Jung-Chin ; Ho-Mok, Kam S. ; Bernardino Morcillo, Carmen ; Kersten, Remco H. J. ; Oude Elferink, Ronald P. J. ; Verhoeven, Arthur J. ; Paulusma, Coen C.
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2022-10, Vol.23 (20), p.12344
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Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms
Author / Creator:Corso, Claudia Rita ; Stipp, Maria Carolina ; Radulski, Débora Rasec ; Mariott, Marihá ; da Silva, Luisa Mota ; de Souza Ramos, Edneia Amancio ; Klassen, Giseli ; Queiroz Telles, José Ederaldo ; Oliveira, Cristhian Santos ; Stefanello, Maria Élida Alves ; Verhoeven, Arthur J. ; Oude Elferink, Ronald P. J. ; Acco, Alexandra
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.16477-16477, Article 16477
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Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR
Author / Creator:Adam, Aziza A. A. ; Jongejan, Aldo ; Moerland, Perry D. ; van der Mark, Vincent A. ; Oude Elferink, Ronald P. ; Chamuleau, Robert A. F. M. ; Hoekstra, Ruurdtje
Publisher:Dordrecht: Springer Netherlands
Journal title:Cytotechnology (Dordrecht), 2020-06, Vol.72 (3), p.377-395
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N-acetylcysteine reduces oxidative stress in sickle cell patients
Author / Creator:Nur, Erfan ; Brandjes, Dees P. ; Teerlink, Tom ; Otten, Hans-Martin ; Oude Elferink, Ronald P. J. ; Muskiet, Frits ; Evers, Ludo M. ; ten Cate, Hugo ; Biemond, Bart J. ; Duits, Ashley J. ; Schnog, John-John B.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2012-07, Vol.91 (7), p.1097-1105
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The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD+ redox state
Author / Creator:Go, Simei ; Kramer, Thorquil T. ; Verhoeven, Arthur J. ; Oude Elferink, Ronald P. J. ; Chang, Jung-Chin
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2021-02, Vol.26 (1-2), p.38-51
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Tissue Distribution and Induction of Human Multidrug Resistant Protein 3
Author / Creator:Scheffer, George L ; Kool, Marcel ; de Haas, Marcel ; de Vree, J Marleen L ; Pijnenborg, Adriana C L M ; Bosman, Diederik K ; Oude Elferink, Ronald P J ; van der Valk, Paul ; Borst, Piet ; Scheper, Rik J
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2002-02, Vol.82 (2), p.193-201
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Showing 1 to 20 of 59 results

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Mechanisms of pruritus in cholestasis: understanding and treating the itch

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Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP

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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling

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Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)

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Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions

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Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

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Glyco-conjugated bile acids drive the initial metaplastic gland formation from multi-layered glands through crypt-fission in a murine model

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Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease—A Comprehensive Review

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A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines

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IgG4-Associated Cholangitis: A Comprehensive Review

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Primary biliary cirrhosis

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ATP8B1 is essential for maintaining normal hearing

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Liver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failure

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Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial

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ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells

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Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms

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Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR

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N-acetylcysteine reduces oxidative stress in sickle cell patients

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The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD+ redox state

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Tissue Distribution and Induction of Human Multidrug Resistant Protein 3

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