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ArticlesPeer ReviewedFull Text
Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand
Author / Creator:Ramesh, Nandini ; Pandey, Udai Bhan
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in molecular neuroscience, 2017-08, Vol.10, p.263-263
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Newsletter articlesFull Text
Researchers engage trash haulers for the sick brain
Author / Creator:Avril, Tom
Publisher:Washington: Tribune Content Agency LLC
Journal title:McClatchy - Tribune News Service, 2007, p.1
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ArticlesPeer ReviewedFull Text
Editorial: Drosophila as a model to study neurodegenerative diseases
Author / Creator:Liguori, Francesco ; Pandey, Udai Bhan ; Digilio, Filomena Anna
Publisher:Lausanne: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2023-08, Vol.17, p.1275253-1275253
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ArticlesPeer ReviewedFull Text
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy
Author / Creator:Marrone, Lara ; Drexler, Hannes C. A. ; Wang, Jie ; Tripathi, Priyanka ; Distler, Tania ; Heisterkamp, Patrick ; Anderson, Eric Nathaniel ; Kour, Sukhleen ; Moraiti, Anastasia ; Maharana, Shovamayee ; Bhatnagar, Rajat ; Belgard, T. Grant ; Tripathy, Vadreenath ; Kalmbach, Norman ; Hosseinzadeh, Zohreh ; Crippa, Valeria ; Abo-Rady, Masin ; Wegner, Florian ; Poletti, Angelo ; Troost, Dirk ; Aronica, Eleonora ; Busskamp, Volker ; Weis, Joachim ; Pandey, Udai Bhan ; Hyman, Anthony A. ; Alberti, Simon ; Goswami, Anand ; Sterneckert, Jared
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2019-07, Vol.138 (1), p.67-84
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ArticlesPeer ReviewedFull Text
HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models
Author / Creator:Silvestri, Beatrice ; Mochi, Michela ; Mawrie, Darilang ; de Turris, Valeria ; Colantoni, Alessio ; Borhy, Beatrice ; Medici, Margherita ; Anderson, Eric Nathaniel ; Garone, Maria Giovanna ; Zammerilla, Christopher Patrick ; Simula, Marco ; Ballarino, Monica ; Pandey, Udai Bhan ; Rosa, Alessandro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.9618-17, Article 9618
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ArticlesPeer ReviewedFull Text
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Author / Creator:Pandey, Udai Bhan ; Nie, Zhiping ; Batlevi, Yakup ; McCray, Brett A. ; Ritson, Gillian P. ; Nedelsky, Natalia B. ; Schwartz, Stephanie L. ; DiProspero, Nicholas A. ; Knight, Melanie A. ; Schuldiner, Oren ; Padmanabhan, Ranjani ; Hild, Marc ; Berry, Deborah L. ; Garza, Dan ; Hubbert, Charlotte C. ; Yao, Tso-Pang ; Baehrecke, Eric H. ; Taylor, J. Paul
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2007-06, Vol.447 (7146), p.860-864
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ArticlesPeer ReviewedFull Text
RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM
Author / Creator:Ramesh, Nandini ; Kour, Sukhleen ; Anderson, Eric N ; Rajasundaram, Dhivyaa ; Pandey, Udai Bhan
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2020-08, Vol.8 (1), p.138-138, Article 138
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ArticlesPeer ReviewedFull Text
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Author / Creator:Prakasam, Ramachandran ; Bonadiman, Angela ; Andreotti, Roberta ; Zuccaro, Emanuela ; Dalfovo, Davide ; Marchioretti, Caterina ; Tripathy, Debasmita ; Petris, Gianluca ; Anderson, Eric N. ; Migazzi, Alice ; Tosatto, Laura ; Cereseto, Anna ; Battaglioli, Elena ; Sorarù, Gianni ; Lim, Wooi Fang ; Rinaldi, Carlo ; Sambataro, Fabio ; Pourshafie, Naemeh ; Grunseich, Christopher ; Romanel, Alessandro ; Pandey, Udai Bhan ; Contestabile, Andrea ; Ronzitti, Giuseppe ; Basso, Manuela ; Pennuto, Maria
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.603-22, Article 603
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Newsletter articlesFull Text
Taking aim at neurodisorders.: At Penn, 'tantalizing' finds in cell research
Author / Creator:Avril, Tom
Publisher:Washington: Tribune Content Agency LLC
Journal title:McClatchy - Tribune Business News, 2007, p.1
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Newsletter articlesFull Text
At Penn, 'tantalizing' finds in cell research: Taking aim at neurodisorders
Author / Creator:Avril, Tom
Publisher:Washington: Tribune Content Agency LLC
Journal title:McClatchy - Tribune Business News, 2007, p.1
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ArticlesPeer ReviewedFull Text
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
Author / Creator:Anderson, Eric N ; Morera, Andrés A ; Kour, Sukhleen ; Cherry, Jonathan D ; Ramesh, Nandini ; Gleixner, Amanda ; Schwartz, Jacob C ; Ebmeier, Christopher ; Old, William ; Donnelly, Christopher J ; Cheng, Jeffrey P ; Kline, Anthony E ; Kofler, Julia ; Stein, Thor D ; Pandey, Udai Bhan
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2021-06, Vol.10
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ArticlesPeer ReviewedFull Text
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo
Author / Creator:Scaramuzzino, Chiara ; Monaghan, John ; Milioto, Carmelo ; Lanson, Jr, Nicholas A ; Maltare, Astha ; Aggarwal, Tanya ; Casci, Ian ; Fackelmayer, Frank O ; Pennuto, Maria ; Pandey, Udai Bhan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e61576
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ArticlesPeer ReviewedFull Text
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
Author / Creator:Casci, Ian ; Krishnamurthy, Karthik ; Kour, Sukhleen ; Tripathy, Vadreenath ; Ramesh, Nandini ; Anderson, Eric N. ; Marrone, Lara ; Grant, Rogan A. ; Oliver, Stacie ; Gochenaur, Lauren ; Patel, Krishani ; Sterneckert, Jared ; Gleixner, Amanda M. ; Donnelly, Christopher J. ; Ruepp, Marc-David ; Sini, Antonella M. ; Zuccaro, Emanuela ; Pennuto, Maria ; Pasinelli, Piera ; Pandey, Udai Bhan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5583-20, Article 5583
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ArticlesPeer ReviewedFull Text
Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2
Author / Creator:Kim, Sang Hwa ; Nichols, Kye D ; Anderson, Eric N ; Liu, Yining ; Ramesh, Nandini ; Jia, Weiyan ; Kuerbis, Connor J ; Scalf, Mark ; Smith, Lloyd M ; Pandey, Udai Bhan ; Tibbetts, Randal S
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2023-04, Vol.12
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ArticlesPeer ReviewedFull Text
Skeletal Muscle Pathogenesis in Polyglutamine Diseases
Author / Creator:Marchioretti, Caterina ; Zuccaro, Emanuela ; Pandey, Udai Bhan ; Rosati, Jessica ; Basso, Manuela ; Pennuto, Maria
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-07, Vol.11 (13), p.2105
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ArticlesPeer ReviewedFull Text
RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3
Author / Creator:Ramesh, Nandini ; Daley, Elizabeth L ; Gleixner, Amanda M ; Mann, Jacob R ; Kour, Sukhleen ; Mawrie, Darilang ; Anderson, Eric N ; Kofler, Julia ; Donnelly, Christopher J ; Kiskinis, Evangelos ; Pandey, Udai Bhan
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2020-10, Vol.8 (1), p.177-20, Article 177
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ArticlesPeer ReviewedFull Text
Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism
Author / Creator:Chivet, Mathilde ; Marchioretti, Caterina ; Pirazzini, Marco ; Piol, Diana ; Scaramuzzino, Chiara ; Polanco, Maria Josè ; Romanello, Vanina ; Zuccaro, Emanuela ; Parodi, Sara ; D'Antonio, Maurizio ; Rinaldi, Carlo ; Sambataro, Fabio ; Pegoraro, Elena ; Soraru, Gianni ; Pandey, Udai Bhan ; Sandri, Marco ; Basso, Manuela ; Pennuto, Maria
Publisher:Switzerland: MDPI
Journal title:Cells (Basel, Switzerland), 2020-01, Vol.9 (2), p.325
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Newspaper ArticlesFull Text
Trash haulers for sick brains; Scientists use genetic manipulation to get fruit flies to reduce toxic buildup of faulty proteins. But can autophagy be harnessed to fight human brain diseases?: Early E...
Author / Creator:Avril, Tom
Publisher:Edmonton, Alta: Postmedia Network Inc
Journal title:Edmonton journal, 2007-06-16
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ArticlesPeer ReviewedFull Text
Dynein light chain 1 is required for autophagy, protein clearance, and cell death in Drosophila
Author / Creator:Batlevi, Yakup ; Martin, Damali N ; Pandey, Udai Bhan ; Simon, Claudio R ; Powers, Christine M ; Taylor, J. Paul ; Baehrecke, Eric H
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (2), p.742-747
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ArticlesPeer ReviewedFull Text
Apolipoprotein B-100 XbaI gene polymorphism in gallbladder cancer
Author / Creator:Singh, Mahendra Kumar ; Pandey, Udai Bhan ; Ghoshal, Uday Chand ; Srivenu, Itha ; Kapoor, Vinay Kumar ; Choudhuri, Gourdas ; Mittal, Balraj
Publisher:Germany: Springer
Journal title:Human genetics, 2004-02, Vol.114 (3), p.280-283
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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

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Researchers engage trash haulers for the sick brain

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Editorial: Drosophila as a model to study neurodegenerative diseases

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FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

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HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

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RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

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LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice

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Taking aim at neurodisorders.: At Penn, 'tantalizing' finds in cell research

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At Penn, 'tantalizing' finds in cell research: Taking aim at neurodisorders

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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

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Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

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Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

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Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2

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Skeletal Muscle Pathogenesis in Polyglutamine Diseases

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RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

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Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism

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Trash haulers for sick brains; Scientists use genetic manipulation to get fruit flies to reduce toxic buildup of faulty proteins. But can autophagy be harnessed to fight human brain diseases?: Early E...

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Dynein light chain 1 is required for autophagy, protein clearance, and cell death in Drosophila

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Apolipoprotein B-100 XbaI gene polymorphism in gallbladder cancer

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