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Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
Author / Creator:Stettler, Karin ; Beltramello, Martina ; Espinosa, Diego A. ; Graham, Victoria ; Cassotta, Antonino ; Bianchi, Siro ; Vanzetta, Fabrizia ; Minola, Andrea ; Jaconi, Stefano ; Mele, Federico ; Foglierini, Mathilde ; Pedotti, Mattia ; Simonelli, Luca ; Dowall, Stuart ; Atkinson, Barry ; Percivalle, Elena ; Simmons, Cameron P. ; Varani, Luca ; Blum, Johannes ; Baldanti, Fausto ; Cameroni, Elisabetta ; Hewson, Roger ; Harris, Eva ; Lanzavecchia, Antonio ; Sallusto, Federica ; Corti, Davide
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6301), p.823-826
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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules
Author / Creator:Stravalaci, Matteo ; Pagani, Isabel ; Paraboschi, Elvezia Maria ; Pedotti, Mattia ; Doni, Andrea ; Scavello, Francesco ; Mapelli, Sarah N. ; Sironi, Marina ; Perucchini, Chiara ; Varani, Luca ; Matkovic, Milos ; Cavalli, Andrea ; Cesana, Daniela ; Gallina, Pierangela ; Pedemonte, Nicoletta ; Capurro, Valeria ; Clementi, Nicola ; Mancini, Nicasio ; Invernizzi, Pietro ; Bayarri-Olmos, Rafael ; Garred, Peter ; Rappuoli, Rino ; Duga, Stefano ; Bottazzi, Barbara ; Uguccioni, Mariagrazia ; Asselta, Rosanna ; Vicenzi, Elisa ; Mantovani, Alberto ; Garlanda, Cecilia
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-02, Vol.23 (2), p.275-286
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Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
Author / Creator:Corti, Davide ; Zhao, Jincun ; Pedotti, Mattia ; Simonelli, Luca ; Agnihothram, Sudhakar ; Fett, Craig ; Fernandez-Rodriguez, Blanca ; Foglierini, Mathilde ; Agatic, Gloria ; Vanzetta, Fabrizia ; Gopal, Robin ; Langrish, Christopher J. ; Barrett, Nicholas A ; Sallusto, Federica ; Baric, Ralph S. ; Varani, Luca ; Zambon, Maria ; Perlman, Stanley ; Lanzavecchia, Antonio
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (33), p.10473-10478
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SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
Author / Creator:Bertoglio, Federico ; Meier, Doris ; Langreder, Nora ; Steinke, Stephan ; Rand, Ulfert ; Simonelli, Luca ; Heine, Philip Alexander ; Ballmann, Rico ; Schneider, Kai-Thomas ; Roth, Kristian Daniel Ralph ; Ruschig, Maximilian ; Riese, Peggy ; Eschke, Kathrin ; Kim, Yeonsu ; Schäckermann, Dorina ; Pedotti, Mattia ; Kuhn, Philipp ; Zock-Emmenthal, Susanne ; Wöhrle, Johannes ; Kilb, Normann ; Herz, Tobias ; Becker, Marlies ; Grasshoff, Martina ; Wenzel, Esther Veronika ; Russo, Giulio ; Kröger, Andrea ; Brunotte, Linda ; Ludwig, Stephan ; Fühner, Viola ; Krämer, Stefan Daniel ; Dübel, Stefan ; Varani, Luca ; Roth, Günter ; Čičin-Šain, Luka ; Schubert, Maren ; Hust, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1577-15, Article 1577
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A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity
Author / Creator:Bardelli, Marco ; Frontzek, Karl ; Simonelli, Luca ; Hornemann, Simone ; Pedotti, Mattia ; Mazzola, Federica ; Carta, Manfredi ; Eckhardt, Valeria ; D'Antuono, Rocco ; Virgilio, Tommaso ; González, Santiago F ; Aguzzi, Adriano ; Varani, Luca
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2018-10, Vol.14 (10), p.e1007335-e1007335
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Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches
Author / Creator:Abba Moussa, Daouda ; Vazquez, Mario ; Chable-Bessia, Christine ; Roux-Portalez, Vincent ; Tamagnini, Elia ; Pedotti, Mattia ; Simonelli, Luca ; Ngo, Giang ; Souchard, Manon ; Lyonnais, Sebastien ; Chentouf, Myriam ; Gros, Nathalie ; Marsile-Medun, Soledad ; Dinter, Heiko ; Pugnière, Martine ; Martineau, Pierre ; Varani, Luca ; Juan, Manel ; Calderon, Hugo ; Naranjo-Gomez, Mar ; Pelegrin, Mireia
Publisher:United States: Earliest : Springer-Nature ; Latest : Taylor & Francis
Journal title:Emerging microbes & infections, 2025-12, Vol.14 (1), p.2432345
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Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin
Author / Creator:Pedotti, Mattia ; Simonelli, Luca ; Livoti, Elsa ; Varani, Luca
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2011-01, Vol.12 (1), p.226-251
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Rational engineering of a human anti-dengue antibody through experimentally validated computational docking
Author / Creator:Simonelli, Luca ; Pedotti, Mattia ; Beltramello, Martina ; Livoti, Elsa ; Calzolai, Luigi ; Sallusto, Federica ; Lanzavecchia, Antonio ; Varani, Luca
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e55561-e55561
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Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology
Author / Creator:Peissert, Frederik ; Pedotti, Mattia ; Corbellari, Riccardo ; Simonelli, Luca ; De Gasparo, Raoul ; Tamagnini, Elia ; Plüss, Louis ; Elsayed, Abdullah ; Matasci, Mattia ; De Luca, Roberto ; Cassaniti, Irene ; Sammartino, Jose' Camilla ; Piralla, Antonio ; Baldanti, Fausto ; Neri, Dario ; Varani, Luca
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Global challenges, 2023-10, Vol.7 (10), p.2300088-n/a
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Rational modification of estrogen receptor by combination of computational and experimental analysis
Author / Creator:Ferrero, Valentina Elisabetta Viviana ; Pedotti, Mattia ; Chiadò, Alessandro ; Simonelli, Luca ; Calzolai, Luigi ; Varani, Luca ; Lettieri, Teresa
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e102658-e102658
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Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors
Author / Creator:La Spina, Rita ; Ferrero, Valentina E V ; Aiello, Venera ; Pedotti, Mattia ; Varani, Luca ; Lettieri, Teresa ; Calzolai, Luigi ; Haasnoot, Willem ; Colpo, Pascal
Publisher:Switzerland: MDPI AG
Journal title:Biosensors (Basel), 2017-12, Vol.8 (1), p.1
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Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
Author / Creator:De Gasparo, Raoul ; Pedotti, Mattia ; Simonelli, Luca ; Nickl, Petr ; Muecksch, Frauke ; Cassaniti, Irene ; Percivalle, Elena ; Lorenzi, Julio C. C. ; Mazzola, Federica ; Magrì, Davide ; Michalcikova, Tereza ; Haviernik, Jan ; Honig, Vaclav ; Mrazkova, Blanka ; Polakova, Natalie ; Fortova, Andrea ; Tureckova, Jolana ; Iatsiuk, Veronika ; Di Girolamo, Salvatore ; Palus, Martin ; Zudova, Dagmar ; Bednar, Petr ; Bukova, Ivana ; Bianchini, Filippo ; Mehn, Dora ; Nencka, Radim ; Strakova, Petra ; Pavlis, Oto ; Rozman, Jan ; Gioria, Sabrina ; Sammartino, Josè Camilla ; Giardina, Federica ; Gaiarsa, Stefano ; Pan-Hammarström, Qiang ; Barnes, Christopher O. ; Bjorkman, Pamela J. ; Calzolai, Luigi ; Piralla, Antonio ; Baldanti, Fausto ; Nussenzweig, Michel C. ; Bieniasz, Paul D. ; Hatziioannou, Theodora ; Prochazka, Jan ; Sedlacek, Radislav ; Robbiani, Davide F. ; Ruzek, Daniel ; Varani, Luca
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7859), p.424-428
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Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
Author / Creator:Muri, Jonathan ; Cecchinato, Valentina ; Cavalli, Andrea ; Shanbhag, Akanksha A. ; Matkovic, Milos ; Biggiogero, Maira ; Maida, Pier Andrea ; Moritz, Jacques ; Toscano, Chiara ; Ghovehoud, Elaheh ; Furlan, Raffaello ; Barbic, Franca ; Voza, Antonio ; De Nadai, Guendalina ; Cervia, Carlo ; Zurbuchen, Yves ; Taeschler, Patrick ; Murray, Lilly A. ; Danelon-Sargenti, Gabriela ; Moro, Simone ; Gong, Tao ; Piffaretti, Pietro ; Bianchini, Filippo ; Crivelli, Virginia ; Podešvová, Lucie ; Pedotti, Mattia ; Jarrossay, David ; Sgrignani, Jacopo ; Thelen, Sylvia ; Uhr, Mario ; Bernasconi, Enos ; Rauch, Andri ; Manzo, Antonio ; Ciurea, Adrian ; Rocchi, Marco B. L. ; Varani, Luca ; Moser, Bernhard ; Bottazzi, Barbara ; Thelen, Marcus ; Fallon, Brian A. ; Boyman, Onur ; Mantovani, Alberto ; Garzoni, Christian ; Franzetti-Pellanda, Alessandra ; Uguccioni, Mariagrazia ; Robbiani, Davide F.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-04, Vol.24 (4), p.604-611
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A conformational switch controlling the toxicity of the prion protein
Author / Creator:Frontzek, Karl ; Bardelli, Marco ; Senatore, Assunta ; Henzi, Anna ; Reimann, Regina R. ; Bedir, Seden ; Marino, Marika ; Hussain, Rohanah ; Jurt, Simon ; Meisl, Georg ; Pedotti, Mattia ; Mazzola, Federica ; Siligardi, Giuliano ; Zerbe, Oliver ; Losa, Marco ; Knowles, Tuomas ; Lakkaraju, Asvin ; Zhu, Caihong ; Schwarz, Petra ; Hornemann, Simone ; Holt, Matthew G. ; Simonelli, Luca ; Varani, Luca ; Aguzzi, Adriano
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2022-08, Vol.29 (8), p.831-840
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Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer
Author / Creator:Guerrini, Giuditta ; Mehn, Dora ; Fumagalli, Francesco ; Gioria, Sabrina ; Pedotti, Mattia ; Simonelli, Luca ; Bianchini, Filippo ; Robbiani, Davide F ; Varani, Luca ; Calzolai, Luigi
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-10, Vol.24 (19), p.14875
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Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19
Author / Creator:Asselta, Rosanna ; Paraboschi, Elvezia Maria ; Stravalaci, Matteo ; Invernizzi, Pietro ; Bonfanti, Paolo ; Biondi, Andrea ; Pagani, Isabel ; Pedotti, Mattia ; Doni, Andrea ; Scavello, Francesco ; Mapelli, Sarah N. ; Sironi, Marina ; Perucchini, Chiara ; Varani, Luca ; Matkovic, Milos ; Cavalli, Andrea ; Cesana, Daniela ; Gallina, Pierangela ; Pedemonte, Nicoletta ; Capurro, Valeria ; Clementi, Nicola ; Mancini, Nicasio ; Bayarri-Olmos, Rafael ; Garred, Peter ; Rappuoli, Rino ; Duga, Stefano ; Bottazzi, Barbara ; Uguccioni, Mariagrazia ; Vicenzi, Elisa ; Mantovani, Alberto ; Garlanda, Cecilia
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-06, Vol.23 (6), p.865-867
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Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
Author / Creator:De Gasparo, Raoul ; Pedotti, Mattia ; Simonelli, Luca ; Nickl, Petr ; Muecksch, Frauke ; Cassaniti, Irene ; Percivalle, Elena ; Lorenzi, Julio C. C. ; Mazzola, Federica ; Magrì, Davide ; Michalcikova, Tereza ; Haviernik, Jan ; Honig, Vaclav ; Mrazkova, Blanka ; Polakova, Natalie ; Fortova, Andrea ; Tureckova, Jolana ; Iatsiuk, Veronika ; Di Girolamo, Salvatore ; Palus, Martin ; Zudova, Dagmar ; Bednar, Petr ; Bukova, Ivana ; Bianchini, Filippo ; Mehn, Dora ; Nencka, Radim ; Strakova, Petra ; Pavlis, Oto ; Rozman, Jan ; Gioria, Sabrina ; Sammartino, Josè Camilla ; Giardina, Federica ; Gaiarsa, Stefano ; Pan-Hammarström, Qiang ; Barnes, Christopher O. ; Bjorkman, Pamela J. ; Calzolai, Luigi ; Piralla, Antonio ; Baldanti, Fausto ; Nussenzweig, Michel C. ; Bieniasz, Paul D. ; Hatziioannou, Theodora ; Prochazka, Jan ; Sedlacek, Radislav ; Robbiani, Davide F. ; Ruzek, Daniel ; Varani, Luca
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-09, Vol.597 (7874), p.E2-E2
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Rationally modified estrogen receptor protein as a bio-recognition element for the detection of EDC pollutants: strategies and opportunities
Author / Creator:Pedotti, Mattia ; Ferrero, Valentina Elisabetta Viviana ; Lettieri, Teresa ; Colpo, Pascal ; Follonier, Stephane ; Calzolai, Luigi ; Varani, Luca
Publisher:Switzerland: MDPI AG
Journal title:International journal of environmental research and public health, 2015-02, Vol.12 (3), p.2612-2621
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Receptor-based high-throughput screening and identification of estrogens in dietary supplements using bioaffinity liquid-chromatography ion mobility mass spectrometry
Author / Creator:Aqai, Payam ; Blesa, Natalia Gómez ; Major, Hilary ; Pedotti, Mattia ; Varani, Luca ; Ferrero, Valentina E. V. ; Haasnoot, Willem ; Nielen, Michel W. F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2013-11, Vol.405 (29), p.9427-9436
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Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2
Author / Creator:Bianchini, Filippo ; Crivelli, Virginia ; Abernathy, Morgan E ; Guerra, Concetta ; Palus, Martin ; Muri, Jonathan ; Marcotte, Harold ; Piralla, Antonio ; Pedotti, Mattia ; De, Raoul ; Simonelli, Luca ; Matkovic, Milos ; Toscano, Chiara ; Biggiogero, Maira ; Calvaruso, Veronica ; Svoboda, Pavel ; Tomas Cervantes Rincon ; Fava, Tommaso ; Podesvova, Lucie ; Shanbhag, Akanksha A ; Celoria, Andrea ; Sgrignani, Jacopo ; Stefanik, Michal ; Hoenig, Vaclav ; Pranclova, Veronika ; Michalcikova, Tereza ; Prochazka, Jan ; Guerrini, Giuditta ; Mehn, Dora ; Ciabattini, Annalisa ; Abolhassani, Hassan ; Jarrossay, David ; Uguccioni, Mariagrazia ; Medaglini, Donata ; Pan-Hammarstroem, Qiang ; Calzolai, Luigi ; Fernandez, Daniel ; Baldanti, Fausto ; Franzetti-Pellanda, Alessandra ; Garzoni, Christian ; Sedlacek, Radislav ; Ruzek, Daniel ; Varani, Luca ; Cavalli, Andrea ; Barnes, Christopher O ; Robbiani, Davide F
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-11
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Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

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Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

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SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

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A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

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Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches

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Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin

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Rational engineering of a human anti-dengue antibody through experimentally validated computational docking

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Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology

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Rational modification of estrogen receptor by combination of computational and experimental analysis

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Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors

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Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

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Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course

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A conformational switch controlling the toxicity of the prion protein

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Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer

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Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19

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Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

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Rationally modified estrogen receptor protein as a bio-recognition element for the detection of EDC pollutants: strategies and opportunities

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Receptor-based high-throughput screening and identification of estrogens in dietary supplements using bioaffinity liquid-chromatography ion mobility mass spectrometry

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Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2

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