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ArticlesPeer ReviewedFull Text
Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)
Author / Creator:Hübner, Alexandra ; Petersen, Bjoern ; Keil, Günther M. ; Niemann, Heiner ; Mettenleiter, Thomas C. ; Fuchs, Walter
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-01, Vol.8 (1), p.1449-7, Article 1449
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Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
Author / Creator:Hauschild, Janet ; Petersen, Bjoern ; Santiago, Yolanda ; Queisser, Anna-Lisa ; Carnwath, Joseph W ; Lucas-Hahn, Andrea ; Zhang, Lei ; Meng, Xiangdong ; Gregory, Philip D ; Schwinzer, Reinhard ; Cost, Gregory J ; Niemann, Heiner
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.12013-12017
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Optimized Cas9:sgRNA delivery efficiently generates biallelic MSTN knockout sheep without affecting meat quality
Author / Creator:Zhou, Shiwei ; Kalds, Peter ; Luo, Qi ; Sun, Kexin ; Zhao, Xiaoe ; Gao, Yawei ; Cai, Bei ; Huang, Shuhong ; Kou, Qifang ; Petersen, Bjoern ; Chen, Yulin ; Ma, Baohua ; Wang, Xiaolong
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2022-05, Vol.23 (1), p.348-348, Article 348
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Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep
Author / Creator:Wang, Xiaolong ; Liu, Jing ; Niu, Yiyuan ; Li, Yan ; Zhou, Shiwei ; Li, Chao ; Ma, Baohua ; Kou, Qifang ; Petersen, Bjoern ; Sonstegard, Tad ; Huang, Xingxu ; Jiang, Yu ; Chen, Yulin
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2018-05, Vol.19 (1), p.397-397, Article 397
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Generation and first characterization of TRDC-knockout pigs lacking γδ T cells
Author / Creator:Petersen, Bjoern ; Kammerer, Robert ; Frenzel, Antje ; Hassel, Petra ; Dau, Tung Huy ; Becker, Roswitha ; Breithaupt, Angele ; Ulrich, Reiner Georg ; Lucas-Hahn, Andrea ; Meyers, Gregor
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-07, Vol.11 (1), p.14965-14965, Article 14965
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Generation of sheep with defined FecB B and TBXT mutations and porcine blastocysts with KCNJ5 G151R/+ mutation using prime editing
Author / Creator:Zhou, Shiwei ; Lenk, Laura Johanna ; Gao, Yawei ; Wang, Yuhui ; Zhao, Xiaoe ; Pan, Menghao ; Huang, Shuhong ; Sun, Kexin ; Kalds, Peter ; Luo, Qi ; Lillico, Simon ; Sonstegard, Tad ; Scholl, Ute I ; Ma, Baohua ; Petersen, Bjoern ; Chen, Yulin ; Wang, Xiaolong
Publisher:England: BMC
Journal title:BMC genomics, 2023-06, Vol.24 (1), p.313-9
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Molecular scissors and their application in genetically modified farm animals
Author / Creator:Petersen, Bjoern ; Niemann, Heiner
Publisher:Cham: Springer International Publishing
Journal title:Transgenic research, 2015-06, Vol.24 (3), p.381-396
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Advances in genetic modification of farm animals using zinc-finger nucleases (ZFN)
Author / Creator:Petersen, Bjoern ; Niemann, Heiner
Publisher:Dordrecht: Springer Netherlands
Journal title:Chromosome research, 2015-02, Vol.23 (1), p.7-15
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Downregulation of Swine Leukocyte Antigen Expression Decreases the Strength of Xenogeneic Immune Responses towards Renal Proximal Tubular Epithelial Cells
Author / Creator:Schmalkuche, Katharina ; Schwinzer, Reinhard ; Wenzel, Nadine ; Valdivia, Emilio ; Petersen, Björn ; Blasczyk, Rainer ; Figueiredo, Constanca
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-08, Vol.24 (16), p.12711
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Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs
Author / Creator:Kurtz, Stefanie ; Lucas-Hahn, Andrea ; Schlegelberger, Brigitte ; Göhring, Gudrun ; Niemann, Heiner ; Mettenleiter, Thomas C. ; Petersen, Björn
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (2), p.1-9
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CRISPR/Cas12a mediated knock-in of the Polled Celtic variant to produce a polled genotype in dairy cattle
Author / Creator:Schuster, Felix ; Aldag, Patrick ; Frenzel, Antje ; Hadeler, Klaus-Gerd ; Lucas-Hahn, Andrea ; Niemann, Heiner ; Petersen, Björn
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-08, Vol.10 (1), p.13570-13570, Article 13570
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ArticlesPeer ReviewedFull Text
Comparison Between Electroporation at Different Voltage Levels and Microinjection to Generate Porcine Embryos with Multiple Xenoantigen Knock-Outs
Author / Creator:Fernández, Juan Pablo ; Petersen, Björn ; Hassel, Petra ; Lucas Hahn, Andrea ; Kielau, Paul ; Geibel, Johannes ; Kues, Wilfried A
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-11, Vol.25 (22), p.11894
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Generating low immunogenic pig pancreatic islet cell clusters for xenotransplantation
Author / Creator:Carvalho Oliveira, Marco ; Valdivia, Emilio ; Verboom, Murielle ; Yuzefovych, Yuliia ; Sake, Hendrik Johannes ; Pogozhykh, Olena ; Niemann, Heiner ; Schwinzer, Reinhard ; Petersen, Björn ; Seissler, Jochen ; Blasczyk, Rainer ; Figueiredo, Constança
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-05, Vol.24 (9), p.5070-5081
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ArticlesPeer ReviewedFull Text
Generation of sheep with defined FecBB and TBXT mutations and porcine blastocysts with KCNJ5G151R/+ mutation using prime editing
Author / Creator:Zhou, Shiwei ; Lenk, Laura Johanna ; Gao, Yawei ; Wang, Yuhui ; Zhao, Xiaoe ; Pan, Menghao ; Huang, Shuhong ; Sun, Kexin ; Kalds, Peter ; Luo, Qi ; Lillico, Simon ; Sonstegard, Tad ; Scholl, Ute I ; Ma, Baohua ; Petersen, Bjoern ; Chen, Yulin ; Wang, Xiaolong
Publisher:London: BioMed Central Ltd
Journal title:BMC genomics, 2023-06, Vol.24 (1), p.1-313, Article 313
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ArticlesPeer ReviewedFull Text
Genome Editing Strategies to Protect Livestock from Viral Infections
Author / Creator:Söllner, Jenny-Helena ; Mettenleiter, Thomas C ; Petersen, Björn
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2021-10, Vol.13 (10), p.1996
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Decellularized GGTA1-KO pig heart valves do not bind preformed human xenoantibodies
Author / Creator:Ramm, Robert ; Niemann, Heiner ; Petersen, Björn ; Haverich, Axel ; Hilfiker, Andres
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2016-07, Vol.111 (4), p.39-39, Article 39
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ArticlesPeer ReviewedFull Text
Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome
Author / Creator:Garrels, Wiebke ; Mátés, Lajos ; Holler, Stephanie ; Dalda, Anna ; Taylor, Ulrike ; Petersen, Björn ; Niemann, Heiner ; Izsvák, Zsuzsanna ; Ivics, Zoltán ; Kues, Wilfried A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23573-e23573
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ArticlesPeer ReviewedFull Text
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2
Author / Creator:Hinkel, Rabea ; Trenkwalder, Teresa ; Petersen, Björn ; Husada, Wira ; Gesenhues, Florian ; Lee, Seungmin ; Hannappel, Ewald ; Bock-Marquette, Ildiko ; Theisen, Daniel ; Leitner, Laura ; Boekstegers, Peter ; Cierniewski, Czeslaw ; Müller, Oliver J. ; le Noble, Ferdinand ; Adams, Ralf H. ; Weinl, Christine ; Nordheim, Alfred ; Reichart, Bruno ; Weber, Christian ; Olson, Eric ; Posern, Guido ; Deindl, Elisabeth ; Niemann, Heiner ; Kupatt, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-06, Vol.5 (1), p.3970-3970, Article 3970
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Efficient Knock-in of a Point Mutation in Porcine Fibroblasts Using the CRISPR/Cas9- GMNN Fusion Gene
Author / Creator:Gerlach, Max ; Kraft, Theresia ; Brenner, Bernhard ; Petersen, Björn ; Niemann, Heiner ; Montag, Judith
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2018-06, Vol.9 (6), p.296
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Hyperbaric oxygen treatment reveals spatiotemporal OXPHOS plasticity in the porcine heart
Author / Creator:Heidler, Juliana ; Cabrera-Orefice, Alfredo ; Wittig, Ilka ; Heyne, Estelle ; Tomczak, Jan-Niklas ; Petersen, Bjoern ; Henze, Dirk ; Pohjoismäki, Jaakko L O ; Szibor, Marten
Publisher:US: Oxford University Press
Journal title:PNAS nexus, 2024-06, Vol.3 (6), p.pgae210-pgae210
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Showing 1 to 20 of 40 results

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Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)

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Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

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Optimized Cas9:sgRNA delivery efficiently generates biallelic MSTN knockout sheep without affecting meat quality

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Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep

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Generation and first characterization of TRDC-knockout pigs lacking γδ T cells

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Generation of sheep with defined FecB B and TBXT mutations and porcine blastocysts with KCNJ5 G151R/+ mutation using prime editing

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Molecular scissors and their application in genetically modified farm animals

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Advances in genetic modification of farm animals using zinc-finger nucleases (ZFN)

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Downregulation of Swine Leukocyte Antigen Expression Decreases the Strength of Xenogeneic Immune Responses towards Renal Proximal Tubular Epithelial Cells

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Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs

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CRISPR/Cas12a mediated knock-in of the Polled Celtic variant to produce a polled genotype in dairy cattle

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Comparison Between Electroporation at Different Voltage Levels and Microinjection to Generate Porcine Embryos with Multiple Xenoantigen Knock-Outs

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Generating low immunogenic pig pancreatic islet cell clusters for xenotransplantation

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Generation of sheep with defined FecBB and TBXT mutations and porcine blastocysts with KCNJ5G151R/+ mutation using prime editing

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Genome Editing Strategies to Protect Livestock from Viral Infections

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Decellularized GGTA1-KO pig heart valves do not bind preformed human xenoantibodies

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Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome

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MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2

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Efficient Knock-in of a Point Mutation in Porcine Fibroblasts Using the CRISPR/Cas9- GMNN Fusion Gene

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Hyperbaric oxygen treatment reveals spatiotemporal OXPHOS plasticity in the porcine heart

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