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Random mutagenesis of the nucleotide-binding domain of NRC1 (NB-LRR Required for Hypersensitive Response-Associated Cell Death-1), a downstream signalling nucleotide-binding, leucine-rich repeat (NB-L...
Author / Creator:Sueldo, Daniela J. ; Shimels, Mahdere ; Spiridon, Laurentiu N. ; Caldararu, Octav ; Petrescu, Andrei‐Jose ; Joosten, Matthieu H. A. J. ; Tameling, Wladimir I. L.
Publisher:England: New Phytologist Trust
Journal title:The New phytologist, 2015-10, Vol.208 (1), p.210-223
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Differential Inhibition by Cenobamate of Canonical Human Nav1.5 Ion Channels and Several Point Mutants
Author / Creator:Şulea, Teodor Asvadur ; Draga, Sorin ; Mernea, Maria ; Corlan, Alexandru Dan ; Radu, Beatrice Mihaela ; Petrescu, Andrei-Jose ; Amuzescu, Bogdan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (1), p.358
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Lessons from Deep Learning Structural Prediction of Multistate Multidomain Proteins—The Case Study of Coiled-Coil NOD-like Receptors
Author / Creator:Șulea, Teodor Asvadur ; Martin, Eliza Cristina ; Bugeac, Cosmin Alexandru ; Bectaș, Floriana Sibel ; Iacob, Anca-L ; Spiridon, Laurențiu ; Petrescu, Andrei-Jose
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (2), p.500
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Insights into RAG Evolution from the Identification of “Missing Link” Family A RAGL Transposons
Author / Creator:Martin, Eliza C ; Le Targa, Lorlane ; Tsakou-Ngouafo, Louis ; Fan, Tzu-Pei ; Lin, Che-Yi ; Xiao, Jianxiong ; Huang, Ziwen ; Yuan, Shaochun ; Xu, Anlong ; Su, Yi-Hsien ; Petrescu, Andrei-Jose ; Pontarotti, Pierre ; Schatz, David G
Publisher:US: Oxford University Press
Journal title:Molecular biology and evolution, 2023-11, Vol.40 (11)
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Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation
Author / Creator:Papadopoulos, Nicolas ; Nédélec, Audrey ; Derenne, Allison ; Şulea, Teodor Asvadur ; Pecquet, Christian ; Chachoua, Ilyas ; Vertenoeil, Gaëlle ; Tilmant, Thomas ; Petrescu, Andrei-Jose ; Mazzucchelli, Gabriel ; Iorga, Bogdan I. ; Vertommen, Didier ; Constantinescu, Stefan N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.1881-1881, Article 1881
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Genome-wide functional analyses of plant coiled–coil NLR-type pathogen receptors reveal essential roles of their N-terminal domain in oligomerization, networking, and immunity
Author / Creator:Wróblewski, Tadeusz ; Spiridon, Laurentiu ; Martin, Eliza Cristina ; Petrescu, Andrei-Jose ; Cavanaugh, Keri ; Truco, Maria José ; Xu, Huaqin ; Gozdowski, Dariusz ; Pawłowski, Krzysztof ; Michelmore, Richard W. ; Takken, Frank L.W.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2018-12, Vol.16 (12), p.e2005821-e2005821
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Nucleocytoplasmic Distribution Is Required for Activation of Resistance by the Potato NB-LRR Receptor Rx1 and Is Balanced by Its Functional Domains
Author / Creator:Slootweg, Erik ; Roosien, Jan ; Spiridon, Laurentiu N ; Petrescu, Andrei-Jose ; Tameling, Wladimir ; Joosten, Matthieu ; Pomp, Rikus ; van Schaik, Casper ; Dees, Robert ; Borst, Jan Willem ; Smant, Geert ; Schots, Arjen ; Bakker, Jaap ; Goverse, Aska
Publisher:England: American Society of Plant Biologists
Journal title:The Plant cell, 2010-12, Vol.22 (12), p.4195-4215
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Structural Determinants at the Interface of the ARC2 and Leucine-Rich Repeat Domains Control the Activation of the Plant Immune Receptors Rx1 and Gpa2
Author / Creator:Slootweg, Erik J. ; Spiridon, Laurentiu N. ; Roosien, Jan ; Butterbach, Patrick ; Pomp, Rikus ; Westerhof, Lotte ; Wilbers, Ruud ; Bakker, Erin ; Bakker, Jaap ; Petrescu, Andrei-José ; Smant, Geert ; Goverse, Aska
Publisher:Rockville, MD: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2013-07, Vol.162 (3), p.1510-1528
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LRRpredictor—A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an Ensemble of Classifiers
Author / Creator:Martin, Eliza C. ; Sukarta, Octavina C. A. ; Spiridon, Laurentiu ; Grigore, Laurentiu G. ; Constantinescu, Vlad ; Tacutu, Robi ; Goverse, Aska ; Petrescu, Andrei-Jose
Publisher:Switzerland: MDPI
Journal title:Genes, 2020-03, Vol.11 (3), p.286
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ArticlesPeer ReviewedFull Text
Tyrosinase Degradation Is Prevented when EDEM1 Lacks the Intrinsically Disordered Region
Author / Creator:Marin, Marioara B. ; Ghenea, Simona ; Spiridon, Laurentiu N. ; Chiritoiu, Gabriela N. ; Petrescu, Andrei-Jose ; Petrescu, Stefana-Maria
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-08, Vol.7 (8), p.e42998-e42998
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C-Terminus Glycans with Critical Functional Role in the Maturation of Secretory Glycoproteins
Author / Creator:Cioaca, Daniela ; Ghenea, Simona ; Spiridon, Laurentiu N. ; Marin, Marioara ; Petrescu, Andrei-Jose ; Petrescu, Stefana M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-05, Vol.6 (5), p.e19979-e19979
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A Caenorhabditis elegans Wild Type Defies the Temperature-Size Rule Owing to a Single Nucleotide Polymorphism in tra-3
Author / Creator:Kammenga, J.E ; Doroszuk, A ; Riksen, J.A.G ; Hazendonk, E ; Spiridon, L ; Petrescu, A.J ; Tijsterman, M ; Plasterk, R.H.A ; Bakker, J
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2007-03, Vol.3 (3), p.e34-e34
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ArticlesPeer ReviewedFull Text
Interface Analysis of the Complex between ERK2 and PTP-SL
Author / Creator:Balasu, Mihaela C. ; Spiridon, Laurentiu N. ; Miron, Simona ; Craescu, Constantin T. ; Scheidig, Axel J. ; Petrescu, Andrei-Jose ; Szedlacsek, Stefan E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-05, Vol.4 (5), p.e5432-e5432
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Heavy metal accumulation by Saccharomyces cerevisiae cells armed with metal binding hexapeptides targeted to the inner face of the plasma membrane
Author / Creator:Ruta, Lavinia Liliana ; Kissen, Ralph ; Nicolau, Ioana ; Neagoe, Aurora Daniela ; Petrescu, Andrei José ; Bones, Atle M. ; Farcasanu, Ileana Cornelia
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2017-07, Vol.101 (14), p.5749-5763
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COMPUTATIONAL ASSISTED RESEARCH IN MOLECULAR LIFE SCIENCES
Author / Creator:Petrescu, Andrei Jose
Publisher:Timisoara: West University of Timisoara, Faculty of Chemistry
Journal title:New Frontiers in Chemistry, 2017-04, Vol.26 (2), p.S1_OP1-S1_OP1
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EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning
Author / Creator:Manica, Georgiana ; Ghenea, Simona ; Munteanu, Cristian V. A. ; Martin, Eliza C. ; Butnaru, Cristian ; Surleac, Marius ; Chiritoiu, Gabriela N. ; Alexandru, Petruta R. ; Petrescu, Andrei-Jose ; Petrescu, Stefana M.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-02, Vol.22 (4), p.2172
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Distinct Roles of Non-Overlapping Surface Regions of the Coiled-Coil Domain in the Potato Immune Receptor Rx1
Author / Creator:Slootweg, Erik J. ; Spiridon, Laurentiu N. ; Martin, Eliza C. ; Tameling, Wladimir I.L. ; Townsend, Philip D. ; Pomp, Rikus ; Roosien, Jan ; Drawska, Olga ; Sukarta, Octavina C.A. ; Schots, Arjen ; Borst, Jan Willem ; Joosten, Matthieu H.A.J. ; Bakker, Jaap ; Smant, Geert ; Cann, Martin J. ; Petrescu, Andrei-Jose ; Goverse, Aska
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2018-11, Vol.178 (3), p.1310-1331
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Random mutagenesis of the nucleotide‐binding domain of NRC 1 ( NB ‐ LRR Required for Hypersensitive Response‐Associated Cell Death‐1), a downstream signalling nucleotide‐binding, leucine‐rich repeat (...
Author / Creator:Sueldo, Daniela J. ; Shimels, Mahdere ; Spiridon, Laurentiu N. ; Caldararu, Octav ; Petrescu, Andrei‐Jose ; Joosten, Matthieu H. A. J. ; Tameling, Wladimir I. L.
Journal title:The New phytologist, 2015-10, Vol.208 (1), p.210-223
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IN SILICO INVESTIGATION OF PROTEIN-LIGAND INTERACTION
Author / Creator:Milac, Adina-Luminiţa ; Surleac, Marius ; Martin, Eliza ; Petrescu, Andrei-Jose
Publisher:Timisoara: West University of Timisoara, Faculty of Chemistry
Journal title:New Frontiers in Chemistry, 2017-04, Vol.26 (2), p.S1_OP2-S1_OP2
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AN INTEGRATED WORKFLOW FOR THE IDENTIFICATION OF AN ERAD MENNOSIDASE POTENTIAL SUBSTRATES
Author / Creator:Munteanu, Cristian V A ; Chiriţoiu, Gabriela N ; Petrescu, Andrei-Jose ; Petrescu, Ştefana M
Publisher:Timisoara: West University of Timisoara, Faculty of Chemistry
Journal title:New Frontiers in Chemistry, 2017-04, Vol.26 (2), p.S2_P20-S2_P20
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Random mutagenesis of the nucleotide-binding domain of NRC1 (NB-LRR Required for Hypersensitive Response-Associated Cell Death-1), a downstream signalling nucleotide-binding, leucine-rich repeat (NB-L...

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Differential Inhibition by Cenobamate of Canonical Human Nav1.5 Ion Channels and Several Point Mutants

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Lessons from Deep Learning Structural Prediction of Multistate Multidomain Proteins—The Case Study of Coiled-Coil NOD-like Receptors

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Insights into RAG Evolution from the Identification of “Missing Link” Family A RAGL Transposons

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Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation

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Genome-wide functional analyses of plant coiled–coil NLR-type pathogen receptors reveal essential roles of their N-terminal domain in oligomerization, networking, and immunity

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Nucleocytoplasmic Distribution Is Required for Activation of Resistance by the Potato NB-LRR Receptor Rx1 and Is Balanced by Its Functional Domains

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Structural Determinants at the Interface of the ARC2 and Leucine-Rich Repeat Domains Control the Activation of the Plant Immune Receptors Rx1 and Gpa2

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LRRpredictor—A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an Ensemble of Classifiers

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Tyrosinase Degradation Is Prevented when EDEM1 Lacks the Intrinsically Disordered Region

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C-Terminus Glycans with Critical Functional Role in the Maturation of Secretory Glycoproteins

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A Caenorhabditis elegans Wild Type Defies the Temperature-Size Rule Owing to a Single Nucleotide Polymorphism in tra-3

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Interface Analysis of the Complex between ERK2 and PTP-SL

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Heavy metal accumulation by Saccharomyces cerevisiae cells armed with metal binding hexapeptides targeted to the inner face of the plasma membrane

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COMPUTATIONAL ASSISTED RESEARCH IN MOLECULAR LIFE SCIENCES

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EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning

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Distinct Roles of Non-Overlapping Surface Regions of the Coiled-Coil Domain in the Potato Immune Receptor Rx1

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Random mutagenesis of the nucleotide‐binding domain of NRC 1 ( NB ‐ LRR Required for Hypersensitive Response‐Associated Cell Death‐1), a downstream signalling nucleotide‐binding, leucine‐rich repeat (...

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IN SILICO INVESTIGATION OF PROTEIN-LIGAND INTERACTION

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AN INTEGRATED WORKFLOW FOR THE IDENTIFICATION OF AN ERAD MENNOSIDASE POTENTIAL SUBSTRATES

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