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840 results for Phosphatidylserines+-+metabolism

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A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria
Author / Creator:Lahiri, Sujoy ; Chao, Jesse T ; Tavassoli, Shabnam ; Wong, Andrew K O ; Choudhary, Vineet ; Young, Barry P ; Loewen, Christopher J R ; Prinz, William A
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2014-10, Vol.12 (10), p.e1001969-e1001969
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Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
Author / Creator:de Vasconcelos, Nathalia M. ; Van Opdenbosch, Nina ; Van Gorp, Hanne ; Parthoens, Eef ; Lamkanfi, Mohamed
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-01, Vol.26 (1), p.146-161
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Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
Author / Creator:Birge, R B ; Boeltz, S ; Kumar, S ; Carlson, J ; Wanderley, J ; Calianese, D ; Barcinski, M ; Brekken, R A ; Huang, X ; Hutchins, J T ; Freimark, B ; Empig, C ; Mercer, J ; Schroit, A J ; Schett, G ; Herrmann, M
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2016-06, Vol.23 (6), p.962-978
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Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine
Author / Creator:Trinh, Michael N. ; Brown, Michael S. ; Goldstein, Joseph L. ; Han, Jaeil ; Vale, Gonçalo ; McDonald, Jeffrey G. ; Seemann, Joachim ; Mendell, Joshua T. ; Lu, Feiran
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18521-18529
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A phosphoinositide signalling pathway mediates rapid lysosomal repair
Author / Creator:Tan, Jay Xiaojun ; Finkel, Toren
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-09, Vol.609 (7928), p.815-821
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Author / Creator:Liu, Xing ; Zhang, Zhibin ; Ruan, Jianbin ; Pan, Youdong ; Magupalli, Venkat Giri ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.153-158
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ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2 ) and regulate its level at the plasma membrane
Author / Creator:Ghai, Rajesh ; Du, Ximing ; Wang, Huan ; Dong, Jiangqing ; Ferguson, Charles ; Brown, Andrew J ; Parton, Robert G ; Wu, Jia-Wei ; Yang, Hongyuan
Publisher:England: Nature Publishing Group
Journal title:Nature communications, 2017-10, Vol.8 (1), p.757-14, Article 757
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Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
Author / Creator:Segawa, Katsumori ; Kurata, Sachiko ; Yanagihashi, Yuichi ; Brummelkamp, Thijn R. ; Matsuda, Fumihiko ; Nagata, Shigekazu
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-06, Vol.344 (6188), p.1164-1168
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The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
Author / Creator:Graham, Douglas K. ; DeRyckere, Deborah ; Davies, Kurtis D. ; Earp, H. Shelton
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2014-12, Vol.14 (12), p.769-785
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Exposure of phosphatidylserine on the cell surface
Author / Creator:Nagata, S ; Suzuki, J ; Segawa, K ; Fujii, T
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2016-06, Vol.23 (6), p.952-961
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Flipping the dogma - phosphatidylserine in non-apoptotic cell death
Author / Creator:Shlomovitz, Inbar ; Speir, Mary ; Gerlic, Motti
Publisher:England: BioMed Central Ltd
Journal title:Cell communication and signaling, 2019-10, Vol.17 (1), p.139-12, Article 139
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Structural and functional consequences of reversible lipid asymmetry in living membranes
Author / Creator:Doktorova, Milka ; Symons, Jessica L. ; Levental, Ilya
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-12, Vol.16 (12), p.1321-1330
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Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
Author / Creator:Suzuki, Jun ; Denning, Daniel P. ; Imanishi, Eiichi ; Horvitz, H. Robert ; Nagata, Shigekazu
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-07, Vol.341 (6144), p.403-406
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Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53
Author / Creator:Yoon, Kyoung Wan ; Byun, Sanguine ; Kwon, Eunjeong ; Hwang, So-Young ; Chu, Kiki ; Hiraki, Masatsugu ; Jo, Seung-Hee ; Weins, Astrid ; Hakroush, Samy ; Cebulla, Angelika ; Sykes, David B. ; Greka, Anna ; Mundel, Peter ; Fisher, David E. ; Mandinova, Anna ; Lee, Sam W.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-07, Vol.349 (6247), p.499-499
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Viral apoptotic mimicry
Author / Creator:Amara, Ali ; Mercer, Jason
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2015-08, Vol.13 (8), p.461-469
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Initiation of Progressive Morphological Transition Towards an Echino-Stomato-Spherocytic Phenotype by Phosphatidylserine Externalization and Its Implication in Thrombosis
Author / Creator:Bian, Yiying ; Jin, Qiushuo ; Chung, Han-Young ; Lim, Kyung-Min ; Xu, Yuanyuan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-02, Vol.26 (4), p.1747
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Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution
Author / Creator:Tsuji, Takuma ; Cheng, Jinglei ; Tatematsu, Tsuyako ; Ebata, Aoi ; Kamikawa, Hiroki ; Fujita, Akikazu ; Gyobu, Sayuri ; Segawa, Katsumori ; Arai, Hiroyuki ; Taguchi, Tomohiko ; Nagata, Shigekazu ; Fujimoto, Toyoshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (27), p.13368-13373
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Structure and autoregulation of a P4-ATPase lipid flippase
Author / Creator:Timcenko, Milena ; Lyons, Joseph A. ; Januliene, Dovile ; Ulstrup, Jakob J. ; Dieudonné, Thibaud ; Montigny, Cédric ; Ash, Miriam-Rose ; Karlsen, Jesper Lykkegaard ; Boesen, Thomas ; Kühlbrandt, Werner ; Lenoir, Guillaume ; Moeller, Arne ; Nissen, Poul
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7765), p.366-370
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TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets
Author / Creator:Fujii, Toshihiro ; Sakata, Asuka ; Nishimura, Satoshi ; Eto, Koji ; Nagata, Shigekazu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (41), p.12800-12805
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Molecular Mechanisms and Pathophysiological Significance of Eryptosis
Author / Creator:Alghareeb, Sumiah A ; Alfhili, Mohammad A ; Fatima, Sabiha
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-03, Vol.24 (6), p.5079
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A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria

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Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

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Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

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Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

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A phosphoinositide signalling pathway mediates rapid lysosomal repair

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2 ) and regulate its level at the plasma membrane

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Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

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The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer

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Exposure of phosphatidylserine on the cell surface

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Flipping the dogma - phosphatidylserine in non-apoptotic cell death

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Structural and functional consequences of reversible lipid asymmetry in living membranes

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Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

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Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

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Viral apoptotic mimicry

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Initiation of Progressive Morphological Transition Towards an Echino-Stomato-Spherocytic Phenotype by Phosphatidylserine Externalization and Its Implication in Thrombosis

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Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution

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Structure and autoregulation of a P4-ATPase lipid flippase

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TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

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Molecular Mechanisms and Pathophysiological Significance of Eryptosis

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