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ArticlesPeer ReviewedFull Text
Data-informed discovery of hydrolytic nanozymes
Author / Creator:Li, Sirong ; Zhou, Zijun ; Tie, Zuoxiu ; Wang, Bing ; Ye, Meng ; Du, Lei ; Cui, Ran ; Liu, Wei ; Wan, Cuihong ; Liu, Quanyi ; Zhao, Sheng ; Wang, Quan ; Zhang, Yihong ; Zhang, Shuo ; Zhang, Huigang ; Du, Yan ; Wei, Hui
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.827-827, Article 827
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Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
Author / Creator:El Ghachi, Meriem ; Howe, Nicole ; Huang, Chia-Ying ; Olieric, Vincent ; Warshamanage, Rangana ; Touzé, Thierry ; Weichert, Dietmar ; Stansfeld, Phillip J. ; Wang, Meitian ; Kerff, Fred ; Caffrey, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-03, Vol.9 (1), p.1078-13, Article 1078
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Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase
Author / Creator:Chan, Kai Xun ; Mabbitt, Peter D. ; Phua, Su Yin ; Mueller, Jonathan W. ; Nisar, Nazia ; Gigolashvili, Tamara ; Stroeher, Elke ; Grassl, Julia ; Arlt, Wiebke ; Estavillo, Gonzalo M. ; Jackson, Colin J. ; Pogson, Barry J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (31), p.E4567-E4576
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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Author / Creator:Gad, Helge ; Koolmeister, Tobias ; Jemth, Ann-Sofie ; Eshtad, Saeed ; Jacques, Sylvain A. ; Ström, Cecilia E. ; Svensson, Linda M. ; Schultz, Niklas ; Lundbäck, Thomas ; Einarsdottir, Berglind Osk ; Saleh, Aljona ; Göktürk, Camilla ; Baranczewski, Pawel ; Svensson, Richard ; Berntsson, Ronnie P.-A. ; Gustafsson, Robert ; Strömberg, Kia ; Sanjiv, Kumar ; Jacques-Cordonnier, Marie-Caroline ; Desroses, Matthieu ; Gustavsson, Anna-Lena ; Olofsson, Roger ; Johansson, Fredrik ; Homan, Evert J. ; Loseva, Olga ; Bräutigam, Lars ; Johansson, Lars ; Höglund, Andreas ; Hagenkort, Anna ; Pham, Therese ; Altun, Mikael ; Gaugaz, Fabienne Z. ; Vikingsson, Svante ; Evers, Bastiaan ; Henriksson, Martin ; Vallin, Karl S. A. ; Wallner, Olov A. ; Hammarström, Lars G. J. ; Wiita, Elisee ; Almlöf, Ingrid ; Kalderén, Christina ; Axelsson, Hanna ; Djureinovic, Tatjana ; Puigvert, Jordi Carreras ; Häggblad, Maria ; Jeppsson, Fredrik ; Martens, Ulf ; Lundin, Cecilia ; Lundgren, Bo ; Granelli, Ingrid ; Jensen, Annika Jenmalm ; Artursson, Per ; Nilsson, Jonas A. ; Stenmark, Pål ; Scobie, Martin ; Berglund, Ulrika Warpman ; Helleday, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-04, Vol.508 (7495), p.215-221
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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Author / Creator:Huber, Kilian V. M. ; Salah, Eidarus ; Radic, Branka ; Gridling, Manuela ; Elkins, Jonathan M. ; Stukalov, Alexey ; Jemth, Ann-Sofie ; Göktürk, Camilla ; Sanjiv, Kumar ; Strömberg, Kia ; Pham, Therese ; Berglund, Ulrika Warpman ; Colinge, Jacques ; Bennett, Keiryn L. ; Loizou, Joanna I. ; Helleday, Thomas ; Knapp, Stefan ; Superti-Furga, Giulio
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-04, Vol.508 (7495), p.222-227
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Near-infrared optogenetic pair for protein regulation and spectral multiplexing
Author / Creator:Redchuk, Taras A ; Omelina, Evgeniya S ; Chernov, Konstantin G ; Verkhusha, Vladislav V
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-06, Vol.13 (6), p.633-639
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A large-scale method to measure absolute protein phosphorylation stoichiometries
Author / Creator:Wu, Ronghu ; Haas, Wilhelm ; Dephoure, Noah ; Huttlin, Edward L ; Zhai, Bo ; Sowa, Mathew E ; Gygi, Steven P
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2011-07, Vol.8 (8), p.677-683
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ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
Author / Creator:Humbert, Melissa C ; Weihbrecht, Katie ; Searby, Charles C ; Li, Yalan ; Pope, Robert M ; Sheffield, Val C ; Seo, Seongjin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19691-19696
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ArticlesPeer ReviewedFull Text
Interactions between RNA polymerase and the "core recognition element" counteract pausing
Author / Creator:Vvedenskaya, Irina O. ; Vahedian-Movahed, Hanif ; Bird, Jeremy G. ; Knoblauch, Jared G. ; Goldman, Seth R. ; Zhang, Yu ; Ebright, Richard H. ; Nickels, Bryce E.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-06, Vol.344 (6189), p.1285-1289
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ArticlesPeer ReviewedFull Text
Modular evolution of phosphorylation-based signalling systems
Author / Creator:Jin, Jing ; Pawson, Tony
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2012-09, Vol.367 (1602), p.2540-2555
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Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure
Author / Creator:Sakuragi, Takaharu ; Kosako, Hidetaka ; Nagata, Shigekazu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (8), p.2907-2912
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Interaction between S4 and the phosphatase domain mediates electrochemical coupling in voltage-sensing phosphatase (VSP)
Author / Creator:Mizutani, Natsuki ; Kawanabe, Akira ; Jinno, Yuka ; Narita, Hirotaka ; Yonezawa, Tomoko ; Nakagawa, Atsushi ; Okamura, Yasushi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (26), p.1-12
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Structure, regulation, and biological functions of TIGAR and its role in diseases
Author / Creator:Tang, Jie ; Chen, Lei ; Qin, Zheng-hong ; Sheng, Rui
Publisher:Singapore: Springer Singapore
Journal title:Acta pharmacologica Sinica, 2021-10, Vol.42 (10), p.1547-1555
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A Land-Plant-Specific Glycerol-3-Phosphate Acyltransferase Family in Arabidopsis: Substrate Specificity, sn-2 Preference, and Evolution
Author / Creator:Yang, Weili ; Simpson, Jeffrey P. ; Li-Beisson, Yonghua ; Beisson, Fred ; Pollard, Mike ; Ohlrogge, John B.
Publisher:Rockville, MD: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2012-10, Vol.160 (2), p.638-652
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Coupling sensor to enzyme in the voltage sensing phosphatase
Author / Creator:Yu, Yawei ; Zhang, Lin ; Li, Baobin ; Fu, Zhu ; Brohawn, Stephen G. ; Isacoff, Ehud Y.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-07, Vol.15 (1), p.6409-12, Article 6409
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Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies
Author / Creator:Bielas, Stephanie L ; Silhavy, Jennifer L ; Brancati, Francesco ; Kisseleva, Marina V ; Al-Gazali, Lihadh ; Sztriha, Laszlo ; Bayoumi, Riad A ; Zaki, Maha S ; Abdel-Aleem, Alice ; Rosti, Rasim Ozgur ; Kayserili, Hulya ; Swistun, Dominika ; Scott, Lesley C ; Bertini, Enrico ; Boltshauser, Eugen ; Fazzi, Elisa ; Travaglini, Lorena ; Field, Seth J ; Gayral, Stephanie ; Jacoby, Monique ; Schurmans, Stephane ; Dallapiccola, Bruno ; Majerus, Philip W ; Valente, Enza Maria ; Gleeson, Joseph G
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2009-09, Vol.41 (9), p.1032-1036
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Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling
Author / Creator:Workman, Sean D. ; Worrall, Liam J. ; Strynadka, Natalie C. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-03, Vol.9 (1), p.1159-9, Article 1159
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Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction
Author / Creator:Hansen, Scott D. ; Huang, William Y. C. ; Lee, Young Kwang ; Bieling, Peter ; Christensen, Sune M. ; Groves, Jay T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.15013-15022
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A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis
Author / Creator:Raia, Pierre ; Lee, Kitaik ; Bartsch, Simon M. ; Rico-Resendiz, Felix ; Portugal-Calisto, Daniela ; Vadas, Oscar ; Panse, Vikram Govind ; Fiedler, Dorothea ; Hothorn, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1753-20, Article 1753
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Enhancing Machine-Learning Prediction of Enzyme Catalytic Temperature Optima through Amino Acid Conservation Analysis
Author / Creator:Cao, Yinyin ; Qiu, Boyu ; Ning, Xiao ; Fan, Lin ; Qin, Yanmei ; Yu, Dong ; Yang, Chunhe ; Ma, Hongwu ; Liao, Xiaoping ; You, Chun
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-06, Vol.25 (11), p.6252
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Showing 1 to 20 of 230 results

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Data-informed discovery of hydrolytic nanozymes

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Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis

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Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase

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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

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Near-infrared optogenetic pair for protein regulation and spectral multiplexing

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A large-scale method to measure absolute protein phosphorylation stoichiometries

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ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

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Interactions between RNA polymerase and the "core recognition element" counteract pausing

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Modular evolution of phosphorylation-based signalling systems

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Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure

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Interaction between S4 and the phosphatase domain mediates electrochemical coupling in voltage-sensing phosphatase (VSP)

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Structure, regulation, and biological functions of TIGAR and its role in diseases

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A Land-Plant-Specific Glycerol-3-Phosphate Acyltransferase Family in Arabidopsis: Substrate Specificity, sn-2 Preference, and Evolution

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Coupling sensor to enzyme in the voltage sensing phosphatase

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Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies

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Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling

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Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

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A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

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Enhancing Machine-Learning Prediction of Enzyme Catalytic Temperature Optima through Amino Acid Conservation Analysis

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