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19 results for Poreba,+Marcin

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ArticlesPeer ReviewedFull Text
Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity
Author / Creator:Poreba, Marcin ; Salvesen, Guy S ; Drag, Marcin
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2017-10, Vol.12 (10), p.2189-2214
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Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling
Author / Creator:Kasperkiewicz, Paulina ; Poreba, Marcin ; Snipas, Scott J. ; Parker, Heather ; Winterbourn, Christine C. ; Salvesen, Guy S. ; Drag, Marcin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2518-2523
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Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells
Author / Creator:Poreba, Marcin ; Rut, Wioletta ; Groborz, Katarzyna ; Snipas, Scott J. ; Salvesen, Guy S. ; Drag, Marcin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-12, Vol.26 (12), p.2695-2709
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Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells
Author / Creator:Groborz, Katarzyna ; Gonzalez Ramirez, Monica L. ; Snipas, Scott J. ; Salvesen, Guy S. ; Drąg, Marcin ; Poręba, Marcin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-02, Vol.27 (2), p.451-465
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Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad
Author / Creator:Zeiler, Evelyn ; List, Anja ; Alte, Ferdinand ; Gersch, Malte ; Wachtel, Rudolf ; Poreba, Marcin ; Drag, Marcin ; Groll, Michael ; Sieber, Stephan A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (28), p.11302-11307
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Betulin and Its Derivatives Reduce Inflammation and COX-2 Activity in Macrophages
Author / Creator:Szlasa, Wojciech ; Ślusarczyk, Sylwester ; Nawrot-Hadzik, Izabela ; Abel, Renata ; Zalesińska, Aleksandra ; Szewczyk, Anna ; Sauer, Natalia ; Preissner, Robert ; Saczko, Jolanta ; Drąg, Marcin ; Poręba, Marcin ; Daczewska, Małgorzata ; Kulbacka, Julita ; Drąg-Zalesińska, Małgorzata
Publisher:New York: Springer US
Journal title:Inflammation, 2023-04, Vol.46 (2), p.573-583
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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4
Author / Creator:Kasperkiewicz, Paulina ; Poreba, Marcin ; Snipas, Scott J. ; Lin, S. Jack ; Kirchhofer, Daniel ; Salvesen, Guy S. ; Drag, Marcin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-07, Vol.10 (7), p.e0132818-e0132818
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
Author / Creator:Drąg-Zalesińska, Małgorzata ; Drąg, Marcin ; Poręba, Marcin ; Borska, Sylwia ; Kulbacka, Julita ; Saczko, Jolanta
Publisher:England: BioMed Central
Journal title:Cancer cell international, 2017-01, Vol.17 (1), p.4-4, Article 4
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Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes
Author / Creator:Kasperkiewicz, Paulina ; Kołt, Sonia ; Janiszewski, Tomasz ; Groborz, Katarzyna ; Poręba, Marcin ; Snipas, Scott J. ; Salvesen, Guy S. ; Drąg, Marcin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-10, Vol.8 (1), p.15998-10, Article 15998
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Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C
Author / Creator:Poreba, Marcin ; Mihelic, Marko ; Krai, Priscilla ; Rajkovic, Jelena ; Krezel, Artur ; Pawelczak, Malgorzata ; Klemba, Michael ; Turk, Dusan ; Turk, Boris ; Latajka, Rafal ; Drag, Marcin
Publisher:Vienna: Springer-Verlag
Journal title:Amino acids, 2014-04, Vol.46 (4), p.931-943
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Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum
Author / Creator:Poreba, Marcin ; McGowan, Sheena ; Skinner-Adams, Tina S. ; Trenholme, Katharine R. ; Gardiner, Donald L. ; Whisstock, James C. ; To, Joyce ; Salvesen, Guy S. ; Dalton, John P. ; Drag, Marcin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e31938-e31938
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ArticlesPeer ReviewedFull Text
Caspase selective reagents for diagnosing apoptotic mechanisms
Author / Creator:Poreba, Marcin ; Groborz, Katarzyna ; Navarro, Mario ; Snipas, Scott J. ; Drag, Marcin ; Salvesen, Guy S.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-02, Vol.26 (2), p.229-244
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Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families
Author / Creator:Poreba, Marcin ; Szalek, Aleksandra ; Rut, Wioletta ; Kasperkiewicz, Paulina ; Rutkowska-Wlodarczyk, Izabela ; Snipas, Scott J. ; Itoh, Yoshifumi ; Turk, Dusan ; Turk, Boris ; Overall, Christopher M. ; Kaczmarek, Leszek ; Salvesen, Guy S. ; Drag, Marcin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-02, Vol.7 (1), p.43135-43135, Article 43135
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Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates
Author / Creator:Poreba, M ; Kasperkiewicz, P ; Snipas, S J ; Fasci, D ; Salvesen, G S ; Drag, M
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2014-09, Vol.21 (9), p.1482-1492
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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4: e0132818
Author / Creator:Kasperkiewicz, Paulina ; Poreba, Marcin ; Snipas, Scott J ; Lin, S Jack ; Kirchhofer, Daniel ; Salvesen, Guy S ; Drag, Marcin
Journal title:PloS one, 2015-07, Vol.10 (7)
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Delivery of caspase inhibitors through GSDMD pores to inhibit pyroptosis
Author / Creator:Groborz, Katarzyna M ; Truong, Melissa E ; Stowe, Irma ; Lee, Bettina ; Jones, Robert S ; Plise, Emile ; Levy, Elizabeth S ; Kou, Ponien ; Lee, Wyne P ; Zhang, Juan ; Nguyen, Julia ; Kalinka, Malgorzata ; Drag, Marcin ; Kayagaki, Nobuhiko ; Newton, Kim ; Poreba, Marcin ; Dixit, Vishva
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2025-02
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The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes)
Author / Creator:Poreba, Marcin ; Groborz, Katarzyna ; Wioletta Rut ; Pore, Milind ; Snipas, Scott J ; Vizovisek, Matej ; Turk, Boris ; Drag, Marcin ; Salvesen, Guy S
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-09
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Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent...
Author / Creator:De Vries, Laura E ; Sanchez, Mateo Isidrio ; Groborz, Katarzyna ; Kuppens, Laurie ; Poreba, Marcin ; Lehmann, Christine ; Yuan, Fang ; Arastu-Kapur, Shirin ; Horn, Martin ; Mares, Michael ; Bogyo, Matthew ; Drag, Marcin ; Deu, Edgar
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-08
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Acknowledgment to Reviewers of Toxics in 2020
Author / Creator:Toxics Editorial Office
Publisher:Switzerland: MDPI AG
Journal title:Toxics (Basel), 2021-01, Vol.9 (2), p.17
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Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity

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Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling

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Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells

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Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells

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Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad

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Betulin and Its Derivatives Reduce Inflammation and COX-2 Activity in Macrophages

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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)

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Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

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Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C

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Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum

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Caspase selective reagents for diagnosing apoptotic mechanisms

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Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families

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Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates

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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4: e0132818

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Delivery of caspase inhibitors through GSDMD pores to inhibit pyroptosis

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The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes)

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Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent...

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Acknowledgment to Reviewers of Toxics in 2020

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