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28 results for Proia,+David

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ArticlesPeer ReviewedFull Text
Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol
Author / Creator:Blackman, Ronald K. ; Cheung-Ong, Kahlin ; Gebbia, Marinella ; Proia, David A. ; He, Suqin ; Kepros, Jane ; Jonneaux, Aurelie ; Marchetti, Philippe ; Kluza, Jerome ; Rao, Patricia E. ; Wada, Yumiko ; Giaever, Guri ; Nislow, Corey
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-01, Vol.7 (1), p.e29798
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ArticlesPeer ReviewedFull Text
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models
Author / Creator:Whitesell, Luke ; Santagata, Sandro ; Mendillo, Marc L. ; Lin, Nancy U. ; Proia, David A. ; Lindquist, Susan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (51), p.18297-18302
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ArticlesPeer ReviewedFull Text
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes
Author / Creator:Mbofung, Rina M. ; McKenzie, Jodi A. ; Malu, Shruti ; Zhang, Min ; Peng, Weiyi ; Liu, Chengwen ; Kuiatse, Isere ; Tieu, Trang ; Williams, Leila ; Devi, Seram ; Ashkin, Emily ; Xu, Chunyu ; Huang, Lu ; Zhang, Minying ; Talukder, Amjad H. ; Tripathi, Satyendra C. ; Khong, Hiep ; Satani, Nikunj ; Muller, Florian L. ; Roszik, Jason ; Heffernan, Timothy ; Allison, James P. ; Lizee, Gregory ; Hanash, Sam M. ; Proia, David ; Amaria, Rodabe ; Davis, R. Eric ; Hwu, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.451-8, Article 451
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Newsletter articlesFull Text
Proia David, He Suqin and Synta Pharmaceuticals Corp Apply for Patent on Prostate Cancer Therapy with HSP90 Inhibitory Compounds
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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ArticlesPeer ReviewedFull Text
Reconstruction of human mammary tissues in a mouse model
Author / Creator:Proia, David A ; Kuperwasser, Charlotte
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2006-06, Vol.1 (1), p.206-214
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ArticlesPeer ReviewedFull Text
The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer
Author / Creator:He, Suqin ; Smith, Donald L. ; Sequeira, Manuel ; Sang, Jim ; Bates, Richard C. ; Proia, David A.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-08, Vol.32 (4), p.577-586
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Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling
Author / Creator:Proia, David A. ; Foley, Kevin P. ; Korbut, Tim ; Sang, Jim ; Smith, Don ; Bates, Richard C. ; Liu, Yuan ; Rosenberg, Alex F. ; Zhou, Dan ; Koya, Keizo ; Barsoum, James ; Blackman, Ronald K.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-04, Vol.6 (4), p.e18552
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Newsletter articlesFull Text
Proia David, He Suqin and Synta Pharmaceuticals Corp Submit United States Patent Application for Combination Therapy of Hsp90 Inhibitory Compounds with CHK Inhibitors
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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Newsletter articlesFull Text
Foley Kevin P, Proia David and Synta Pharmaceuticals Corp Apply for Patent on Combination Therapy of HSP90 Inhibitory Compounds with Radiotherapy
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Medical Patent News, 2014
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, EL-HARIRY IMAN, PROIA DAVID, VUKOVIC VOJO FOR "TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS" (AMERICAN INVENTORS)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2013
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, PROIA DAVID, HE SUQIN FOR "COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH CHK INHIBITORS" (AMERICAN INVENTORS)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2012
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, PROIA DAVID, FRIEDLAND JULIE FOR "COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH PROTEASOME INHIBITORS" (AMERICAN INVENTORS)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2012
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ArticlesPeer ReviewedFull Text
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease
Author / Creator:Seeger-Nukpezah, Tamina ; Proia, David A. ; Egleston, Brian L. ; Nikonova, Anna S. ; Kent, Tatiana ; Cai, Kathy Q. ; Hensley, Harvey H. ; Ying, Weiwen ; Chimmanamada, Dinesh ; Serebriiskii, Ilya G. ; Golemis, Erica A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (31), p.12786-12791
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ArticlesPeer ReviewedFull Text
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer
Author / Creator:Jansson, Keith H. ; Tucker, John B. ; Stahl, Lauren E. ; Simmons, John K. ; Fuller, Caitlyn ; Beshiri, Michael L. ; Agarwal, Supreet ; Fang, Lei ; Hynes, Paul G. ; Alilin, Aian Neil ; Lake, Ross ; Abbey, Yasmine C. ; Cawley, Jacob ; Tice, Caitlin M. ; Yin, JuanJuan ; McKnight, Crystal ; Klummp-Thomas, Carleen ; Zhang, Xiaohu ; Guha, Rajarshi ; Hoover, Shelley ; Simpson, R. Mark ; Nguyen, Holly M. ; Corey, Eva ; Thomas, Craig J. ; Proia, David A. ; Kelly, Kathleen
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-11, Vol.8 (1), p.17239-13, Article 17239
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ArticlesPeer ReviewedFull Text
Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3
Author / Creator:Ganji, Purnachandra Nagaraju ; Park, Wungki ; Wen, Jing ; Mahaseth, Hemchandra ; Landry, Jerome ; Farris, Alton B. ; Willingham, Field ; Sullivan, Patrick S. ; Proia, David A. ; El-Hariry, Iman ; Taliaferro-Smith, LaTonia ; Diaz, Roberto ; El-Rayes, Bassel F.
Publisher:Dordrecht: Springer Netherlands
Journal title:Angiogenesis (London), 2013-10, Vol.16 (4), p.903-917
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ArticlesPeer ReviewedFull Text
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression
Author / Creator:HE, SUQIN ; ZHANG, CHAOHUA ; SHAFI, AYESHA A ; SEQUEIRA, MANUEL ; ACQUAVIVA, JAIME ; FRIEDLAND, JULIE C ; SANG, JIM ; SMITH, DONALD L ; WEIGEL, NANCY L ; WADA, YUMIKO ; PROIA, DAVID A
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2013-01, Vol.42 (1), p.35-43
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ArticlesPeer ReviewedFull Text
Inhibiting Heat Shock Protein 90 (HSP90) Limits the Formation of Liver Cysts Induced by Conditional Deletion of Pkd1 in Mice
Author / Creator:Smithline, Zachary B. ; Nikonova, Anna S. ; Hensley, Harvey H. ; Cai, Kathy Q. ; Egleston, Brian L. ; Proia, David A. ; Seeger-Nukpezah, Tamina ; Golemis, Erica A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e114403
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ArticlesPeer ReviewedFull Text
Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes
Author / Creator:Friedland, Julie C. ; Smith, Donald L. ; Sang, Jim ; Acquaviva, Jaime ; He, Suqin ; Zhang, Chaohua ; Proia, David A.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-02, Vol.32 (1), p.14-24
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ArticlesPeer ReviewedFull Text
The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells
Author / Creator:Gomez-Casal, Roberto ; Bhattacharya, Chitralekha ; Epperly, Michael ; Basse, Per ; Wang, Hong ; Wang, Xinhui ; Proia, David ; Greenberger, Joel ; Socinski, Mark ; Levina, Vera
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2015-05, Vol.7 (2), p.876-907
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ArticlesPeer ReviewedFull Text
Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models
Author / Creator:Proia, David A. ; Sang, Jim ; He, Suqin ; Smith, Donald L. ; Sequeira, Manuel ; Zhang, Chaohua ; Liu, Yuan ; Ye, Shuxia ; Zhou, Dan ; Blackman, Ronald K. ; Foley, Kevin P. ; Koya, Keizo ; Wada, Yumiko
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2012-12, Vol.30 (6), p.2201-2209
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Showing 1 to 20 of 28 results

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Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

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HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

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Proia David, He Suqin and Synta Pharmaceuticals Corp Apply for Patent on Prostate Cancer Therapy with HSP90 Inhibitory Compounds

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Reconstruction of human mammary tissues in a mouse model

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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer

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Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling

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Proia David, He Suqin and Synta Pharmaceuticals Corp Submit United States Patent Application for Combination Therapy of Hsp90 Inhibitory Compounds with CHK Inhibitors

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Foley Kevin P, Proia David and Synta Pharmaceuticals Corp Apply for Patent on Combination Therapy of HSP90 Inhibitory Compounds with Radiotherapy

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WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, EL-HARIRY IMAN, PROIA DAVID, VUKOVIC VOJO FOR "TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS" (AMERICAN INVENTORS)

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WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, PROIA DAVID, HE SUQIN FOR "COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH CHK INHIBITORS" (AMERICAN INVENTORS)

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WIPO PUBLISHES PATENT OF SYNTA PHARMACEUTICALS, PROIA DAVID, FRIEDLAND JULIE FOR "COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH PROTEASOME INHIBITORS" (AMERICAN INVENTORS)

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Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease

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High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer

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Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3

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Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression

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Inhibiting Heat Shock Protein 90 (HSP90) Limits the Formation of Liver Cysts Induced by Conditional Deletion of Pkd1 in Mice

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Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes

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The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells

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Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models

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