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ArticlesPeer ReviewedFull Text
GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells
Author / Creator:Chu, I M ; Michalowski, A M ; Hoenerhoff, M ; Szauter, K M ; Luger, D ; Sato, M ; Flanders, K ; Oshima, A ; Csiszar, K ; Green, J E
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2012-04, Vol.31 (16), p.2017-2027
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Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
Author / Creator:Saatci, Ozge ; Kaymak, Aysegul ; Raza, Umar ; Ersan, Pelin G. ; Akbulut, Ozge ; Banister, Carolyn E. ; Sikirzhytski, Vitali ; Tokat, Unal Metin ; Aykut, Gamze ; Ansari, Suhail A. ; Dogan, Hayriye Tatli ; Dogan, Mehmet ; Jandaghi, Pouria ; Isik, Aynur ; Gundogdu, Fatma ; Kosemehmetoglu, Kemal ; Dizdar, Omer ; Aksoy, Sercan ; Akyol, Aytekin ; Uner, Aysegul ; Buckhaults, Phillip J. ; Riazalhosseini, Yasser ; Sahin, Ozgur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2416-2416, Article 2416
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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Author / Creator:Cox, Thomas R ; Rumney, Robin M H ; Schoof, Erwin M ; Perryman, Lara ; Høye, Anette M ; Agrawal, Ankita ; Bird, Demelza ; Latif, Norain Ab ; Forrest, Hamish ; Evans, Holly R ; Huggins, Iain D ; Lang, Georgina ; Linding, Rune ; Gartland, Alison ; Erler, Janine T
Publisher:England: Nature Publishing Group
Journal title:Nature (London), 2015-06, Vol.522 (7554), p.106-110
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Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
Author / Creator:Miller, Bryan W ; Morton, Jennifer P ; Pinese, Mark ; Saturno, Grazia ; Jamieson, Nigel B ; McGhee, Ewan ; Timpson, Paul ; Leach, Joshua ; McGarry, Lynn ; Shanks, Emma ; Bailey, Peter ; Chang, David ; Oien, Karin ; Karim, Saadia ; Au, Amy ; Steele, Colin ; Carter, Christopher Ross ; McKay, Colin ; Anderson, Kurt ; Evans, Thomas R Jeffry ; Marais, Richard ; Springer, Caroline ; Biankin, Andrew ; Erler, Janine T ; Sansom, Owen J
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2015-08, Vol.7 (8), p.1063-1076
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LOXL2—A New Target in Antifibrogenic Therapy?
Author / Creator:Puente, Angela ; Fortea, Jose Ignacio ; Cabezas, Joaquin ; Arias Loste, Maria Teresa ; Iruzubieta, Paula ; Llerena, Susana ; Huelin, Patricia ; Fábrega, Emilio ; Crespo, Javier
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-04, Vol.20 (7), p.1634
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Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor
Author / Creator:Brashear, Sarah E. ; Wohlgemuth, Ross P. ; Hu, Lin-Ya ; Jbeily, Elias H. ; Christiansen, Blaine A. ; Smith, Lucas R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-10, Vol.17 (10), p.e0271776-e0271776
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Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition
Author / Creator:Berman, Alycia G. ; Romary, Daniel J. ; Kerr, Katherine E. ; Gorazd, Natalyn E. ; Wigand, Morgan M. ; Patnaik, Sourav S. ; Finol, Ender A. ; Cox, Abigail D. ; Goergen, Craig J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-01, Vol.12 (1), p.99-13, Article 99
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Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
Author / Creator:Tang, HaoRan ; Leung, Leo ; Saturno, Grazia ; Viros, Amaya ; Smith, Duncan ; Di Leva, Gianpiero ; Morrison, Eamonn ; Niculescu-Duvaz, Dan ; Lopes, Filipa ; Johnson, Louise ; Dhomen, Nathalie ; Springer, Caroline ; Marais, Richard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-04, Vol.8 (1), p.14909-14909, Article 14909
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Lysyl oxidase mediates regeneration of chondrocytes and extracellular matrix in the construction of tissue-engineered cartilage in vitro
Author / Creator:Chen, Jie ; Zheng, Rui ; Zhang, Peiling ; Fan, Hao ; Jiang, Hong ; Zhou, Guangdong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-05, Vol.15 (1), p.16697-11, Article 16697
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Lysyl oxidase is essential for hypoxia-induced metastasis
Author / Creator:Erler, Janine T. ; Bennewith, Kevin L. ; Nicolau, Monica ; Dornhöfer, Nadja ; Kong, Christina ; Le, Quynh-Thu ; Chi, Jen-Tsan Ashley ; Jeffrey, Stefanie S. ; Giaccia, Amato J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-04, Vol.440 (7088), p.1222-1226
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Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics
Author / Creator:Mammoto, Akiko ; Mammoto, Tadanori ; Kanapathipillai, Mathumai ; Wing Yung, Chong ; Jiang, Elisabeth ; Jiang, Amanda ; Lofgren, Kristopher ; Gee, Elaine P.S. ; Ingber, Donald E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013-04, Vol.4 (1), p.1759-1759, Article 1759
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Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice
Author / Creator:Leiva, Orly ; Ng, Seng Kah ; Matsuura, Shinobu ; Chitalia, Vipul ; Lucero, Hector ; Findlay, Alison ; Turner, Craig ; Jarolimek, Wolfgang ; Ravid, Katya
Publisher:Tokyo: Springer Japan
Journal title:International journal of hematology, 2019-12, Vol.110 (6), p.699-708
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Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies
Author / Creator:Knitlova, Jarmila ; Doubkova, Martina ; Eckhardt, Adam ; Ostadal, Martin ; Musilkova, Jana ; Bacakova, Lucie ; Novotny, Tomas
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-11, Vol.22 (21), p.11903
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Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer
Author / Creator:Nilsson, Maria ; Adamo, Hanibal ; Bergh, Anders ; Halin Bergström, Sofia
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-01, Vol.6 (1), p.19608-19608, Article 19608
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2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities
Author / Creator:Kouzi, Olympia ; Pontiki, Eleni ; Hadjipavlou-Litina, Dimitra
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-12, Vol.24 (23), p.4411
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Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice
Author / Creator:Kondo, Masateru ; Izawa-Ishizawa, Yuki ; Goda, Mitsuhiro ; Hosooka, Mayuko ; Kagimoto, Yuu ; Saito, Naoko ; Matsuoka, Rie ; Zamami, Yoshito ; Chuma, Masayuki ; Yagi, Kenta ; Takechi, Kenshi ; Tsuneyama, Koichi ; Ishizawa, Keisuke
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (19), p.7226
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Targeting lysyl oxidase reduces peritoneal fibrosis
Author / Creator:Harlow, Christopher R. ; Wu, Xuan ; van Deemter, Marielle ; Gardiner, Fiona ; Poland, Craig ; Green, Rebecca ; Sarvi, Sana ; Brown, Pamela ; Kadler, Karl E. ; Lu, Yinhui ; Mason, J. Ian ; Critchley, Hilary O. D. ; Hillier, Stephen G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-08, Vol.12 (8), p.e0183013
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ArticlesPeer ReviewedFull Text
Effect of Lysyl Oxidase Inhibition on Angiotensin II-Induced Arterial Hypertension, Remodeling, and Stiffness
Author / Creator:Eberson, Lance S. ; Sanchez, Pablo A. ; Majeed, Beenish A. ; Tawinwung, Supannikar ; Secomb, Timothy W. ; Larson, Douglas F.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-04, Vol.10 (4), p.e0124013-e0124013
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Mechanisms of homocysteine toxicity in humans
Publisher:Vienna: Springer Nature B.V
Journal title:Amino acids, 2007-05, Vol.32 (4), p.561-572
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β-Aminopropionitrile-Induced Reduction in Enzymatic Crosslinking Causes In Vitro Changes in Collagen Morphology and Molecular Composition
Author / Creator:Canelón, Silvia P. ; Wallace, Joseph M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-11, Vol.11 (11), p.e0166392-e0166392
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Showing 1 to 20 of 40 results

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GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells

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Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer

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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

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LOXL2—A New Target in Antifibrogenic Therapy?

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Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

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Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition

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Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

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Lysyl oxidase mediates regeneration of chondrocytes and extracellular matrix in the construction of tissue-engineered cartilage in vitro

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Lysyl oxidase is essential for hypoxia-induced metastasis

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Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics

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Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice

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Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies

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Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer

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2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities

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Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice

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Targeting lysyl oxidase reduces peritoneal fibrosis

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Effect of Lysyl Oxidase Inhibition on Angiotensin II-Induced Arterial Hypertension, Remodeling, and Stiffness

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Mechanisms of homocysteine toxicity in humans

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β-Aminopropionitrile-Induced Reduction in Enzymatic Crosslinking Causes In Vitro Changes in Collagen Morphology and Molecular Composition

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