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ArticlesPeer ReviewedFull Text
Regulatory R-loops as facilitators of gene expression and genome stability
Author / Creator:Niehrs, Christof ; Luke, Brian
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2020-03, Vol.21 (3), p.167-178
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R-loops as Janus-faced modulators of DNA repair
Author / Creator:Marnef, Aline ; Legube, Gaëlle
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2021-04, Vol.23 (4), p.305-313
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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites
Author / Creator:Promonet, Alexy ; Padioleau, Ismaël ; Liu, Yaqun ; Sanz, Lionel ; Biernacka, Anna ; Schmitz, Anne-Lyne ; Skrzypczak, Magdalena ; Sarrazin, Amélie ; Mettling, Clément ; Rowicka, Maga ; Ginalski, Krzysztof ; Chedin, Frédéric ; Chen, Chun-Long ; Lin, Yea-Lih ; Pasero, Philippe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.3940-12, Article 3940
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R-loop-dependent promoter-proximal termination ensures genome stability
Author / Creator:Xu, Congling ; Li, Chengyu ; Chen, Jiwei ; Xiong, Yan ; Qiao, Zhibin ; Fan, Pengyu ; Li, Conghui ; Ma, Shuangyu ; Liu, Jin ; Song, Aixia ; Tao, Bolin ; Xu, Tao ; Xu, Wei ; Chi, Yayun ; Xue, Jingyan ; Wang, Pu ; Ye, Dan ; Gu, Hongzhou ; Zhang, Peng ; Wang, Qiong ; Xiao, Ruijing ; Cheng, Jingdong ; Zheng, Hai ; Yu, Xiaoli ; Zhang, Zhen ; Wu, Jiong ; Liang, Kaiwei ; Liu, Yan-Jun ; Lu, Huasong ; Chen, Fei Xavier
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-09, Vol.621 (7979), p.610-619
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RNA transcripts stimulate homologous recombination by forming DR-loops
Author / Creator:Ouyang, Jian ; Yadav, Tribhuwan ; Zhang, Jia-Min ; Yang, Haibo ; Rheinbay, Esther ; Guo, Hongshan ; Haber, Daniel A. ; Lan, Li ; Zou, Lee
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-06, Vol.594 (7862), p.283-288
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R-loops as Janus-faced modulators of DNA double-strand break repair
Author / Creator:Marnef, Aline ; Legube, Gaëlle
Publisher:Nature Publishing Group
Journal title:Nature cell biology, 2021-04, Vol.23 (4), p.305-313
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R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
Author / Creator:Mosler, Thorsten ; Conte, Francesca ; Longo, Gabriel M. C. ; Mikicic, Ivan ; Kreim, Nastasja ; Möckel, Martin M. ; Petrosino, Giuseppe ; Flach, Johanna ; Barau, Joan ; Luke, Brian ; Roukos, Vassilis ; Beli, Petra
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7314-7314, Article 7314
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ArticlesPeer ReviewedFull Text
Proximity labeling identifies a repertoire of site-specific R-loop modulators
Author / Creator:Yan, Qingqing ; Wulfridge, Phillip ; Doherty, John ; Fernandez-Luna, Jose L. ; Real, Pedro J. ; Tang, Hsin-Yao ; Sarma, Kavitha
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.53-53, Article 53
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RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
Author / Creator:Cristini, Agnese ; Tellier, Michael ; Constantinescu, Flavia ; Accalai, Clelia ; Albulescu, Laura Oana ; Heiringhoff, Robin ; Bery, Nicolas ; Sordet, Olivier ; Murphy, Shona ; Gromak, Natalia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2961-2961, Article 2961
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BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage
Author / Creator:Vohhodina, Jekaterina ; Goehring, Liana J. ; Liu, Ben ; Kong, Qing ; Botchkarev Jr, Vladimir V. ; Huynh, Mai ; Liu, Zhiqi ; Abderazzaq, Fieda O. ; Clark, Allison P. ; Ficarro, Scott B. ; Marto, Jarrod A. ; Hatchi, Elodie ; Livingston, David M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3542-3542, Article 3542
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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability
Author / Creator:Prendergast, Lisa ; McClurg, Urszula L. ; Hristova, Rossitsa ; Berlinguer-Palmini, Rolando ; Greener, Sarah ; Veitch, Katie ; Hernandez, Inmaculada ; Pasero, Philippe ; Rico, Daniel ; Higgins, Jonathan M. G. ; Gospodinov, Anastas ; Papamichos-Chronakis, Manolis
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.4534-4534, Article 4534
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ArticlesPeer ReviewedFull Text
The RNA m5C modification in R-loops as an off switch of Alt-NHEJ
Author / Creator:Yang, Haibo ; Lachtara, Emily M. ; Ran, Xiaojuan ; Hopkins, Jessica ; Patel, Parasvi S. ; Zhu, Xueping ; Xiao, Yao ; Phoon, Laiyee ; Gao, Boya ; Zou, Lee ; Lawrence, Michael S. ; Lan, Li
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-09, Vol.14 (1), p.6114-15, Article 6114
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ArticlesPeer ReviewedFull Text
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
Author / Creator:Cofsky, Joshua C ; Karandur, Deepti ; Huang, Carolyn J ; Witte, Isaac P ; Kuriyan, John ; Doudna, Jennifer A
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-06, Vol.9
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ArticlesPeer ReviewedFull Text
Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding
Author / Creator:Liu, Pengyu ; Lusk, Jacob ; Jonoska, Nataša ; Vázquez, Mariel
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2024-12, Vol.20 (12), p.e1012669
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ArticlesPeer ReviewedFull Text
PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Author / Creator:Jayakumar, Sundarraj ; Patel, Manthan ; Boulet, Fanny ; Aziz, Hadicha ; Brooke, Greg N. ; Tummala, Hemanth ; Pradeepa, Madapura M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.361-14, Article 361
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ArticlesPeer ReviewedFull Text
Harmful R-loops are prevented via different cell cycle-specific mechanisms
Author / Creator:San Martin-Alonso, Marta ; Soler-Oliva, María E. ; García-Rubio, María ; García-Muse, Tatiana ; Aguilera, Andrés
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4451-4451, Article 4451
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MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts
Author / Creator:Chang, Emily Yun-Chia ; Tsai, Shuhe ; Aristizabal, Maria J. ; Wells, James P. ; Coulombe, Yan ; Busatto, Franciele F. ; Chan, Yujia A. ; Kumar, Arun ; Dan Zhu, Yi ; Wang, Alan Ying-Hsu ; Fournier, Louis-Alexandre ; Hieter, Philip ; Kobor, Michael S. ; Masson, Jean-Yves ; Stirling, Peter C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4265-15, Article 4265
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ArticlesPeer ReviewedFull Text
RNA abasic sites in yeast and human cells
Author / Creator:Liu, Yaojuan ; Rodriguez, Yesenia ; Ross, Robert L. ; Zhao, Ruoxia ; Watts, Jason A. ; Grunseich, Christopher ; Bruzel, Alan ; Li, Dongjun ; Burdick, Joshua T. ; Prasad, Rajendra ; Crouch, Robert J. ; Limbach, Patrick A. ; Wilson, Samuel H. ; Cheung, Vivian G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (34), p.20689-20695
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DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis
Author / Creator:Li, Qin ; Zhou, Jincong ; Li, Shuai ; Zhang, Weifeng ; Du, Yingxue ; Li, Kuan ; Wang, Yingxiang ; Sun, Qianwen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7763-7763, Article 7763
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Structure and genome editing of type I-B CRISPR-Cas
Author / Creator:Lu, Meiling ; Yu, Chenlin ; Zhang, Yuwen ; Ju, Wenjun ; Ye, Zhi ; Hua, Chenyang ; Mao, Jinze ; Hu, Chunyi ; Yang, Zhenhuang ; Xiao, Yibei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-05, Vol.15 (1), p.4126-4126, Article 4126
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Showing 1 to 20 of 44 results

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Regulatory R-loops as facilitators of gene expression and genome stability

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R-loops as Janus-faced modulators of DNA repair

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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

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R-loop-dependent promoter-proximal termination ensures genome stability

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RNA transcripts stimulate homologous recombination by forming DR-loops

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R-loops as Janus-faced modulators of DNA double-strand break repair

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R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability

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Proximity labeling identifies a repertoire of site-specific R-loop modulators

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RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation

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BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage

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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability

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The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

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CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

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Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding

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PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity

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Harmful R-loops are prevented via different cell cycle-specific mechanisms

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MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts

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RNA abasic sites in yeast and human cells

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DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis

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Structure and genome editing of type I-B CRISPR-Cas

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