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ArticlesPeer ReviewedFull Text
Retinoblastoma Binding Protein 2
Author / Creator:Qi, Lei ; Zhu, Feng ; Li, Shu-hai ; Si, Li-bo ; Hu, Li-kuan ; Tian, Hui
Publisher:Public Library of Science
Journal title:PloS one, 2014-08, Vol.9 (8)
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Retinoblastoma Binding Protein 2 (RBP2) Promotes HIF-1α–VEGF-Induced Angiogenesis of Non-Small Cell Lung Cancer via the Akt Pathway
Author / Creator:Qi, Lei ; Zhu, Feng ; Li, Shu-hai ; Si, Li-bo ; Hu, Li-kuan ; Tian, Hui
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-08, Vol.9 (8), p.e106032-e106032
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Hypoxia induces rapid changes to histone methylation and reprograms chromatin
Author / Creator:Batie, Michael ; Frost, Julianty ; Frost, Mark ; Wilson, James W. ; Schofield, Pieta ; Rocha, Sonia
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6432), p.1222-1226
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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
Author / Creator:Lin, Wenchu ; Cao, Jian ; Liu, Jiayun ; Beshiri, Michael L ; Fujiwara, Yuko ; Francis, Joshua ; Cherniack, Andrew D ; Geisen, Christoph ; Blair, Lauren P ; Zou, Mike R ; Shen, Xiaohua ; Kawamori, Dan ; Liu, Zongzhi ; Grisanzio, Chiara ; Watanabe, Hideo ; Minamishima, Yoji Andrew ; Zhang, Qing ; Kulkarni, Rohit N ; Signoretti, Sabina ; Rodig, Scott J ; Bronson, Roderick T ; Orkin, Stuart H ; Tuck, David P ; Benevolenskaya, Elizaveta V ; Meyerson, Matthew ; Kaelin, William G. Jr ; Yan, Qin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (33), p.13379-13386
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Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212
Author / Creator:Liang, Xiuming ; Zeng, Jiping ; Wang, Lixiang ; Fang, Ming ; Wang, Qing ; Zhao, Min ; Xu, Xia ; Liu, Zhifang ; Li, Wenjuan ; Liu, Shili ; Yu, Han ; Jia, Jihui ; Chen, Chunyan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e69784
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Retinoblastoma-binding protein 2 induces epithelial-mesenchymal transition in esophageal squamous cancer cells
Author / Creator:Qiao, Naian ; Wang, Shikun ; Hu, Likuan
Publisher:Dordrecht: Springer Netherlands
Journal title:Biotechnology letters, 2015-12, Vol.37 (12), p.2365-2370
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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
Author / Creator:Vinogradova, Maia ; Gehling, Victor S ; Gustafson, Amy ; Arora, Shilpi ; Tindell, Charles A ; Wilson, Catherine ; Williamson, Kaylyn E ; Guler, Gulfem D ; Gangurde, Pranoti ; Manieri, Wanda ; Busby, Jennifer ; Flynn, E Megan ; Lan, Fei ; Kim, Hyo-jin ; Odate, Shobu ; Cochran, Andrea G ; Liu, Yichin ; Wongchenko, Matthew ; Yang, Yibin ; Cheung, Tommy K ; Maile, Tobias M ; Lau, Ted ; Costa, Michael ; Hegde, Ganapati V ; Jackson, Erica ; Pitti, Robert ; Arnott, David ; Bailey, Christopher ; Bellon, Steve ; Cummings, Richard T ; Albrecht, Brian K ; Harmange, Jean-Christophe ; Kiefer, James R ; Trojer, Patrick ; Classon, Marie
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-07, Vol.12 (7), p.531-538
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Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype
Author / Creator:Maggi, E C ; Trillo-Tinoco, J ; Struckhoff, A P ; Vijayaraghavan, J ; Del Valle, L ; Crabtree, J S
Publisher:London: Nature Publishing Group UK
Journal title:Oncogenesis (New York, NY), 2016-08, Vol.5 (8), p.e257-e257
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Retinoblastoma Binding Protein 2 Promotes HIF-1[alpha]-VEGF-Induced Angiogenesis of Non-Small Cell Lung Cancer via the Akt Pathway
Author / Creator:Qi, Lei ; Zhu, Feng ; Li, Shu-hai ; Si, Li-bo ; Hu, Li-kuan ; Tian, Hui
Publisher:Public Library of Science
Journal title:PloS one, 2014-08, Vol.9 (8)
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Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
Author / Creator:Greer, Eric L. ; Maures, Travis J. ; Ucar, Duygu ; Hauswirth, Anna G. ; Mancini, Elena ; Lim, Jana P. ; Benayoun, Bérénice A. ; Shi, Yang ; Brunet, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-11, Vol.479 (7373), p.365-371
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Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
Author / Creator:Greer, Eric L. ; Maures, Travis J. ; Hauswirth, Anna G. ; Green, Erin M. ; Leeman, Dena S. ; Maro, Géraldine S. ; Han, Shuo ; Banko, Max R. ; Gozani, Or ; Brunet, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-07, Vol.466 (7304), p.383-387
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Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling
Author / Creator:Longbotham, James E. ; Chio, Cynthia M. ; Dharmarajan, Venkatasubramanian ; Trnka, Michael J. ; Torres, Idelisse Ortiz ; Goswami, Devrishi ; Ruiz, Karen ; Burlingame, Alma L. ; Griffin, Patrick R. ; Fujimori, Danica Galonić
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.94-94, Article 94
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Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis
Author / Creator:Li, Zhuoran ; Zhang, Junyan ; Xu, Tingting ; Hao, Zhiying ; Li, Yadong
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2025-02, Vol.31 (1), p.65-17, Article 65
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AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer
Author / Creator:Zhu, Yingping ; Yang, Wenjuan ; Wang, Xinyan ; Chen, Mengmeng
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2024-11, Vol.65 (5), p.1, Article 107
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Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes
Author / Creator:de Rooij, Jasmijn D E ; Branstetter, Cristyn ; Ma, Jing ; Li, Yongjin ; Walsh, Michael P ; Cheng, Jinjun ; Obulkasim, Askar ; Dang, Jinjun ; Easton, John ; Verboon, Lonneke J ; Mulder, Heather L ; Zimmermann, Martin ; Koss, Cary ; Gupta, Pankaj ; Edmonson, Michael ; Rusch, Michael ; Lim, Joshua Yew Suang ; Reinhardt, Katarina ; Pigazzi, Martina ; Song, Guangchun ; Yeoh, Allen Eng Juh ; Shih, Lee-Yung ; Liang, Der-Cherng ; Halene, Stephanie ; Krause, Diane S ; Zhang, Jinghui ; Downing, James R ; Locatelli, Franco ; Reinhardt, Dirk ; van den Heuvel-Eibrink, Marry M ; Zwaan, C Michel ; Fornerod, Maarten ; Gruber, Tanja A
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-03, Vol.49 (3), p.451-456
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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway
Author / Creator:Luo, Yi ; He, Youzhi ; Xu, Yuxia ; Wang, Yongfu ; Yang, Li
Publisher:England: BioMed Central
Journal title:European journal of medical research, 2025-04, Vol.30 (1), p.284-15, Article 284
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Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion
Author / Creator:Zhang, Yi ; Guo, Yiran ; Gough, Sheryl M. ; Zhang, Jinyong ; Vann, Kendra R. ; Li, Kuai ; Cai, Ling ; Shi, Xiaobing ; Aplan, Peter D. ; Wang, Gang Greg ; Kutateladze, Tatiana G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3339-10, Article 3339
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Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
Author / Creator:Yoo, Jung ; Kim, Go Woon ; Jeon, Yu Hyun ; Kim, Ji Yoon ; Lee, Sang Wu ; Kwon, So Hee
Publisher:London: Nature Publishing Group UK
Journal title:Experimental & molecular medicine, 2022-12, Vol.54 (12), p.2107-2117
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Identification of ryuvidine as a KDM5A inhibitor
Author / Creator:Mitsui, Eishin ; Yoshida, Shogo ; Shinoda, Yui ; Matsumori, Yasumasa ; Tsujii, Hiroshi ; Tsuchida, Mie ; Wada, Shuichi ; Hasegawa, Makoto ; Ito, Akihiro ; Mino, Koshiki ; Onuki, Tetsuo ; Yoshida, Minoru ; Sasaki, Ryuzo ; Mizukami, Tamio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-07, Vol.9 (1), p.9952-10, Article 9952
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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A
Author / Creator:Chaturvedi, Chandra-Prakash ; Somasundaram, Brinda ; Singh, Kulwant ; Carpenedo, Richard L ; Stanford, William L ; Dilworth, F. Jeffrey ; Brand, Marjorie
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18845-18850
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Showing 1 to 20 of 71 results

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Retinoblastoma Binding Protein 2

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Retinoblastoma Binding Protein 2 (RBP2) Promotes HIF-1α–VEGF-Induced Angiogenesis of Non-Small Cell Lung Cancer via the Akt Pathway

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Hypoxia induces rapid changes to histone methylation and reprograms chromatin

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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

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Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212

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Retinoblastoma-binding protein 2 induces epithelial-mesenchymal transition in esophageal squamous cancer cells

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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

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Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype

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Retinoblastoma Binding Protein 2 Promotes HIF-1[alpha]-VEGF-Induced Angiogenesis of Non-Small Cell Lung Cancer via the Akt Pathway

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Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

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Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

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Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

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Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis

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AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer

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Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes

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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway

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Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

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Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis

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Identification of ryuvidine as a KDM5A inhibitor

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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A

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