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129 results for SETD1A

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Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
Author / Creator:Singh, Tarjinder ; Kurki, Mitja I ; Curtis, David ; Purcell, Shaun M ; Crooks, Lucy ; McRae, Jeremy ; Suvisaari, Jaana ; Chheda, Himanshu ; Blackwood, Douglas ; Breen, Gerome ; Pietiläinen, Olli ; Gerety, Sebastian S ; Ayub, Muhammad ; Blyth, Moira ; Cole, Trevor ; Collier, David ; Coomber, Eve L ; Craddock, Nick ; Daly, Mark J ; Danesh, John ; DiForti, Marta ; Foster, Alison ; Freimer, Nelson B ; Geschwind, Daniel ; Johnstone, Mandy ; Joss, Shelagh ; Kirov, Georg ; Körkkö, Jarmo ; Kuismin, Outi ; Holmans, Peter ; Hultman, Christina M ; Iyegbe, Conrad ; Lönnqvist, Jouko ; Männikkö, Minna ; McCarroll, Steve A ; McGuffin, Peter ; McIntosh, Andrew M ; McQuillin, Andrew ; Moilanen, Jukka S ; Moore, Carmel ; Murray, Robin M ; Newbury-Ecob, Ruth ; Ouwehand, Willem ; Paunio, Tiina ; Prigmore, Elena ; Rees, Elliott ; Roberts, David ; Sambrook, Jennifer ; Sklar, Pamela ; Clair, David St ; Veijola, Juha ; Walters, James T R ; Williams, Hywel ; Sullivan, Patrick F ; Hurles, Matthew E ; O'Donovan, Michael C ; Palotie, Aarno ; Owen, Michael J ; Barrett, Jeffrey C
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2016-04, Vol.19 (4), p.571-577
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An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development
Author / Creator:Wang, Rui ; Liu, Jian ; Li, Kai ; Yang, Ganghua ; Chen, Sisi ; Wu, Jie ; Xie, Xinming ; Ren, Hong ; Pang, Yamei
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2021-10, Vol.40 (1), p.318-318, Article 318
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Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome
Author / Creator:Kummeling, Joost ; Stremmelaar, Diante E. ; Raun, Nicholas ; Reijnders, Margot R. F. ; Willemsen, Marjolein H. ; Ruiterkamp-Versteeg, Martina ; Schepens, Marga ; Man, Calvin C. O. ; Gilissen, Christian ; Cho, Megan T. ; McWalter, Kirsty ; Sinnema, Margje ; Wheless, James W. ; Simon, Marleen E. H. ; Genetti, Casie A. ; Casey, Alicia M. ; Terhal, Paulien A. ; van der Smagt, Jasper J. ; van Gassen, Koen L. I. ; Joset, Pascal ; Bahr, Angela ; Steindl, Katharina ; Rauch, Anita ; Keller, Elmar ; Raas-Rothschild, Annick ; Koolen, David A. ; Agrawal, Pankaj B. ; Hoffman, Trevor L. ; Powell-Hamilton, Nina N. ; Thiffault, Isabelle ; Engleman, Kendra ; Zhou, Dihong ; Bodamer, Olaf ; Hoefele, Julia ; Riedhammer, Korbinian M. ; Schwaibold, Eva M. C. ; Tasic, Velibor ; Schubert, Dirk ; Top, Deniz ; Pfundt, Rolph ; Higgs, Martin R. ; Kramer, Jamie M. ; Kleefstra, Tjitske
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-06, Vol.26 (6), p.2013-2024
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In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F)
Author / Creator:Amin, Harem Muhamad ; Szabo, Beata ; Abukhairan, Rawan ; Zeke, Andras ; Kardos, József ; Schad, Eva ; Tantos, Agnes
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-11, Vol.24 (22), p.16032
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Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer
Author / Creator:Ishii, Takeshi ; Akiyama, Yoshimitsu ; Shimada, Shu ; Kabashima, Ayano ; Asano, Daisuke ; Watanabe, Shuichi ; Ishikawa, Yoshiya ; Ueda, Hiroki ; Akahoshi, Keiichi ; Ogawa, Kosuke ; Ono, Hiroaki ; Kudo, Atsushi ; Tanabe, Minoru ; Tanaka, Shinji
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2023-02, Vol.114 (2), p.463-476
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Loss-of-Function Variants in Schizophrenia Risk and SETD1A as a Candidate Susceptibility Gene
Author / Creator:Takata, Atsushi ; Xu, Bin ; Ionita-Laza, Iuliana ; Roos, J. Louw ; Gogos, Joseph A. ; Karayiorgou, Maria
Publisher:United States: Elsevier Inc
Journal title:Neuron (Cambridge, Mass.), 2014-05, Vol.82 (4), p.773-780
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Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation
Author / Creator:Clifton, Nicholas E ; Policicchio, Stefania ; Walker, Emma M ; Castanho, Isabel ; Bosworth, Matthew L ; Saravanaraj, Kirtikesav S ; Burrage, Joe ; Hall, Jeremy ; Dempster, Emma L ; Hannon, Eilis ; Isles, Anthony R ; Mill, Jonathan
Publisher:United States
Journal title:Schizophrenia bulletin, 2025-06
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Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour
Author / Creator:Bosworth, Matthew L. ; Isles, Anthony R. ; Wilkinson, Lawrence S. ; Humby, Trevor
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-08, Vol.19 (8), p.e0298717
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Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a
Author / Creator:Zhao, Ting ; Hong, Yan ; Yan, Bowen ; Huang, Suming ; Ming, Guo-li ; Song, Hongjun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-07, Vol.15 (1), p.5674-15, Article 5674
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SETD1A protects from senescence through regulation of the mitotic gene expression program
Author / Creator:Tajima, Ken ; Matsuda, Satoru ; Yae, Toshifumi ; Drapkin, Benjamin J. ; Morris, Robert ; Boukhali, Myriam ; Niederhoffer, Kira ; Comaills, Valentine ; Dubash, Taronish ; Nieman, Linda ; Guo, Hongshan ; Magnus, Neelima K. C. ; Dyson, Nick ; Shioda, Toshihiro ; Haas, Wilhelm ; Haber, Daniel A. ; Maheswaran, Shyamala
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2854-13, Article 2854
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SETD1A-SOX2 axis is involved in tamoxifen resistance in estrogen receptor α-positive breast cancer cells
Author / Creator:Jin, Ming Li ; Yang, Liu ; Jeong, Kwang Won
Publisher:Wyoming: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2022-01, Vol.12 (13), p.5761-5775
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SETD1A ‐mediated H3K4me3 methylation upregulates lncRNA HOXC‐AS3 and the binding of HOXC‐AS3 to EP300 and increases EP300 stability to suppress the ferroptosis of NSCLC cells
Author / Creator:Shi, Zhenliang ; Zhang, Hao ; Shen, Yimeng ; Zhang, Sipei ; Zhang, Xun ; Xu, Yijun ; Sun, Daqiang
Publisher:Singapore: John Wiley & Sons, Inc
Journal title:Thoracic cancer, 2023-09, Vol.14 (25), p.2579-2590
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Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Author / Creator:Kim, Kun-Yong ; Tanaka, Yoshiaki ; Su, Juan ; Cakir, Bilal ; Xiang, Yangfei ; Patterson, Benjamin ; Ding, Junjun ; Jung, Yong-Wook ; Kim, Ji-Hyun ; Hysolli, Eriona ; Lee, Haelim ; Dajani, Rana ; Kim, Jonghwan ; Zhong, Mei ; Lee, Jeong-Heon ; Skalnik, David ; Lim, Jeong Mook ; Sullivan, Gareth J. ; Wang, Jianlong ; Park, In-Hyun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-07, Vol.9 (1), p.2583-13, Article 2583
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Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development
Author / Creator:Chai, Hongjuan ; Pan, Chunpeng ; Zhang, Mingyang ; Huo, Haizhong ; Shan, Haiyan ; Wu, Jugang
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2023-01, Vol.23 (1), p.96-96, Article 96
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Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer
Author / Creator:Wu, Jugang ; Chai, Hongjuan ; Xu, Xin ; Yu, Jiwei ; Gu, Yan
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2020-06, Vol.14 (6), p.1397-1409
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SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders
Author / Creator:Wang, Shan ; Bleeck, Anna ; Nadif Kasri, Nael ; Kleefstra, Tjitske ; van Rhijn, Jon-Ruben ; Schubert, Dirk
Publisher:Lausanne: Frontiers Research Foundation
Journal title:Frontiers in molecular neuroscience, 2021-11, Vol.14, p.772000-772000
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SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription
Author / Creator:Yang, Liu ; Jin, Mingli ; Park, Sung Jean ; Seo, Seung-Yong ; Jeong, Kwang Won
Publisher:Basel: MDPI AG
Journal title:Cancers, 2020-06, Vol.12 (7), p.1736
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SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
Author / Creator:Tajima, Ken ; Yae, Toshifumi ; Javaid, Sarah ; Tam, Oliver ; Comaills, Valentine ; Morris, Robert ; Wittner, Ben S. ; Liu, Mingzhu ; Engstrom, Amanda ; Takahashi, Fumiyuki ; Black, Joshua C. ; Ramaswamy, Sridhar ; Shioda, Toshihiro ; Hammell, Molly ; Haber, Daniel A. ; Whetstine, Johnathan R. ; Maheswaran, Shyamala
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-09, Vol.6 (1), p.8257-8257, Article 8257
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Histone methyltransferase SETD1A participates in lung cancer progression
Author / Creator:Du, Mei ; Gong, Piping ; Zhang, Yun ; Liu, Yanguo ; Liu, Xiaozhen ; Zhang, Feng ; Wang, Xiuwen
Publisher:Melbourne: John Wiley & Sons Australia, Ltd
Journal title:Thoracic cancer, 2021-08, Vol.12 (16), p.2247-2257
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Metabolic contributions to neuronal deficits caused by genomic disruption of schizophrenia risk gene SETD1A
Author / Creator:Chong, Zheng-Shan ; Khong, Zi Jian ; Tay, Shermaine Huiping ; Ng, Shi-Yan
Publisher:London: Nature Publishing Group
Journal title:NPJ schizophrenia, 2022-12, Vol.8 (1), p.115
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Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

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An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development

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Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome

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In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F)

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Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer

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Loss-of-Function Variants in Schizophrenia Risk and SETD1A as a Candidate Susceptibility Gene

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Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation

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Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour

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Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a

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SETD1A protects from senescence through regulation of the mitotic gene expression program

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SETD1A-SOX2 axis is involved in tamoxifen resistance in estrogen receptor α-positive breast cancer cells

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SETD1A ‐mediated H3K4me3 methylation upregulates lncRNA HOXC‐AS3 and the binding of HOXC‐AS3 to EP300 and increases EP300 stability to suppress the ferroptosis of NSCLC cells

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Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

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Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development

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Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer

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SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders

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SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription

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SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes

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Histone methyltransferase SETD1A participates in lung cancer progression

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Metabolic contributions to neuronal deficits caused by genomic disruption of schizophrenia risk gene SETD1A

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