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ArticlesPeer ReviewedFull Text
Function and information content of DNA methylation
Author / Creator:Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-01, Vol.517 (7534), p.321-326
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ArticlesPeer ReviewedFull Text
Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors
Author / Creator:Barisic, Darko ; Stadler, Michael B. ; Iurlaro, Mario ; Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7754), p.136-140
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ArticlesPeer ReviewedFull Text
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Author / Creator:Yin, Yimeng ; Morgunova, Ekaterina ; Jolma, Arttu ; Kaasinen, Eevi ; Sahu, Biswajyoti ; Khund-Sayeed, Syed ; Das, Pratyush K. ; Kivioja, Teemu ; Dave, Kashyap ; Zhong, Fan ; Nitta, Kazuhiro R. ; Taipale, Minna ; Popov, Alexander ; Ginno, Paul A. ; Domcke, Silvia ; Yan, Jian ; Schübeler, Dirk ; Vinson, Charles ; Taipale, Jussi
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-05, Vol.356 (6337), p.502-502
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ArticlesPeer ReviewedFull Text
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
Author / Creator:Stein, Claudia ; Bardet, Anaïs Flore ; Roma, Guglielmo ; Bergling, Sebastian ; Clay, Ieuan ; Ruchti, Alexandra ; Agarinis, Claudia ; Schmelzle, Tobias ; Bouwmeester, Tewis ; Schübeler, Dirk ; Bauer, Andreas
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-08, Vol.11 (8), p.e1005465
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ArticlesPeer ReviewedFull Text
DNA-binding factors shape the mouse methylome at distal regulatory regions
Author / Creator:Stadler, Michael B. ; Murr, Rabih ; Burger, Lukas ; Ivanek, Robert ; Lienert, Florian ; Schöler, Anne ; Nimwegen, Erik van ; Wirbelauer, Christiane ; Oakeley, Edward J. ; Gaidatzis, Dimos ; Tiwari, Vijay K. ; Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-12, Vol.480 (7378), p.490-495
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ArticlesPeer ReviewedFull Text
A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity
Author / Creator:Ginno, Paul Adrian ; Gaidatzis, Dimos ; Feldmann, Angelika ; Hoerner, Leslie ; Imanci, Dilek ; Burger, Lukas ; Zilbermann, Frederic ; Peters, Antoine H. F. M. ; Edenhofer, Frank ; Smallwood, Sébastien A. ; Krebs, Arnaud R. ; Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2680-16, Article 2680
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ArticlesPeer ReviewedFull Text
Targets and dynamics of promoter DNA methylation during early mouse development
Author / Creator:Borgel, Julie ; Guibert, Sylvain ; Li, Yufeng ; Chiba, Hatsune ; Schübeler, Dirk ; Sasaki, Hiroyuki ; Forné, Thierry ; Weber, Michael
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2010-12, Vol.42 (12), p.1093-1100
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ArticlesPeer ReviewedFull Text
BANP opens chromatin and activates CpG-island-regulated genes
Author / Creator:Grand, Ralph S. ; Burger, Lukas ; Gräwe, Cathrin ; Michael, Alicia K. ; Isbel, Luke ; Hess, Daniel ; Hoerner, Leslie ; Iesmantavicius, Vytautas ; Durdu, Sevi ; Pregnolato, Marco ; Krebs, Arnaud R. ; Smallwood, Sébastien A. ; Thomä, Nicolas ; Vermeulen, Michiel ; Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-08, Vol.596 (7870), p.133-137
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ArticlesPeer ReviewedFull Text
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
Author / Creator:Brykczynska, Urszula ; Hisano, Mizue ; Erkek, Serap ; Ramos, Liliana ; Oakeley, Edward J ; Roloff, Tim C ; Beisel, Christian ; Schübeler, Dirk ; Stadler, Michael B ; Peters, Antoine H F M
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2010-06, Vol.17 (6), p.679-687
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ArticlesPeer ReviewedFull Text
Short sequences can efficiently recruit histone H3 lysine 27 trimethylation in the absence of enhancer activity and DNA methylation
Author / Creator:Jermann, Philip ; Hoerner, Leslie ; Burger, Lukas ; Schübeler, Dirk
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (33), p.E3415-E3421
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ArticlesPeer ReviewedFull Text
Epigenetic Islands in a Genetic Ocean
Author / Creator:Schuebeler, Dirk
Publisher:Washington: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-11, Vol.338 (6108), p.756-757
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ArticlesPeer ReviewedFull Text
Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape
Author / Creator:Ginno, Paul Adrian ; Burger, Lukas ; Seebacher, Jan ; Iesmantavicius, Vytautas ; Schübeler, Dirk
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-10, Vol.9, p.1-12
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ArticlesPeer ReviewedFull Text
Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation
Author / Creator:Hiratani, Ichiro ; Ryba, Tyrone ; Itoh, Mari ; Yokochi, Tomoki ; Schwaiger, Michaela ; Chang, Chia-Wei ; Lyou, Yung ; Townes, Tim M ; Schübeler, Dirk ; Gilbert, David M
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2008-10, Vol.6 (10), p.e245-e245
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ArticlesPeer ReviewedFull Text
Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease
Author / Creator:Gilsbach, Ralf ; Preissl, Sebastian ; Grüning, Björn A. ; Schnick, Tilman ; Burger, Lukas ; Benes, Vladimir ; Würch, Andreas ; Bönisch, Ulrike ; Günther, Stefan ; Backofen, Rolf ; Fleischmann, Bernd K. ; Schübeler, Dirk ; Hein, Lutz
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-10, Vol.5 (1), p.5288, Article 5288
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ArticlesPeer ReviewedFull Text
Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
Author / Creator:Jüttner, Josephine ; Szabo, Arnold ; Gross-Scherf, Brigitte ; Morikawa, Rei K. ; Rompani, Santiago B. ; Hantz, Peter ; Szikra, Tamas ; Esposti, Federico ; Cowan, Cameron S. ; Bharioke, Arjun ; Patino-Alvarez, Claudia P. ; Keles, Özkan ; Kusnyerik, Akos ; Azoulay, Thierry ; Hartl, Dominik ; Krebs, Arnaud R. ; Schübeler, Dirk ; Hajdu, Rozina I. ; Lukats, Akos ; Nemeth, Janos ; Nagy, Zoltan Z. ; Wu, Kun-Chao ; Wu, Rong-Han ; Xiang, Lue ; Fang, Xiao-Long ; Jin, Zi-Bing ; Goldblum, David ; Hasler, Pascal W. ; Scholl, Hendrik P. N. ; Krol, Jacek ; Roska, Botond
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-08, Vol.22 (8), p.1345-1356
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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens
Author / Creator:Barbosa, Inês A. M. ; Gopalakrishnan, Rajaraman ; Mercan, Samuele ; Mourikis, Thanos P. ; Martin, Typhaine ; Wengert, Simon ; Sheng, Caibin ; Ji, Fei ; Lopes, Rui ; Knehr, Judith ; Altorfer, Marc ; Lindeman, Alicia ; Russ, Carsten ; Naumann, Ulrike ; Golji, Javad ; Sprouffske, Kathleen ; Barys, Louise ; Tordella, Luca ; Schübeler, Dirk ; Schmelzle, Tobias ; Galli, Giorgio G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-07, Vol.14 (1), p.3907-15, Article 3907
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Cooperation between bHLH transcription factors and histones for DNA access
Author / Creator:Michael, Alicia K. ; Stoos, Lisa ; Crosby, Priya ; Eggers, Nikolas ; Nie, Xinyu Y. ; Makasheva, Kristina ; Minnich, Martina ; Healy, Kelly L. ; Weiss, Joscha ; Kempf, Georg ; Cavadini, Simone ; Kater, Lukas ; Seebacher, Jan ; Vecchia, Luca ; Chakraborty, Deyasini ; Isbel, Luke ; Grand, Ralph S. ; Andersch, Florian ; Fribourgh, Jennifer L. ; Schübeler, Dirk ; Zuber, Johannes ; Liu, Andrew C. ; Becker, Peter B. ; Fierz, Beat ; Partch, Carrie L. ; Menet, Jerome S. ; Thomä, Nicolas H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-07, Vol.619 (7969), p.385-393
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Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization
Author / Creator:Surdziel, Ewa ; Clay, Ieuan ; Nigsch, Florian ; Thiemeyer, Anke ; Allard, Cyril ; Hoffman, Gregory ; Reece-Hoyes, John S. ; Phadke, Tanushree ; Gambert, Romain ; Keller, Caroline Gubser ; Ludwig, Marie-Gabrielle ; Baumgarten, Birgit ; Frederiksen, Mathias ; Schübeler, Dirk ; Seuwen, Klaus ; Bouwmeester, Tewis ; Fodor, Barna D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-08, Vol.12 (8), p.e0183679
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High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions
Author / Creator:Krebs, Arnaud R ; Dessus-Babus, Sophie ; Burger, Lukas ; Schübeler, Dirk
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-09, Vol.3, p.e04094
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ArticlesPeer ReviewedFull Text
PcG Proteins, DNA Methylation, and Gene Repression by Chromatin Looping
Author / Creator:Tiwari, Vijay K ; McGarvey, Kelly M ; Licchesi, Julien D.F ; Ohm, Joyce E ; Herman, James G ; Schübeler, Dirk ; Baylin, Stephen B
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2008-12, Vol.6 (12), p.e306-e306
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Showing 1 to 20 of 91 results

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Function and information content of DNA methylation

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Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors

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Impact of cytosine methylation on DNA binding specificities of human transcription factors

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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

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DNA-binding factors shape the mouse methylome at distal regulatory regions

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A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity

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Targets and dynamics of promoter DNA methylation during early mouse development

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BANP opens chromatin and activates CpG-island-regulated genes

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Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

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Short sequences can efficiently recruit histone H3 lysine 27 trimethylation in the absence of enhancer activity and DNA methylation

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Epigenetic Islands in a Genetic Ocean

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Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

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Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

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Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

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Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens

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Cooperation between bHLH transcription factors and histones for DNA access

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Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization

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High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions

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PcG Proteins, DNA Methylation, and Gene Repression by Chromatin Looping

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