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92 results for Schertler,+Gebhard

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ArticlesPeer ReviewedFull Text
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
Author / Creator:Venkatakrishnan, A. J. ; Deupi, Xavier ; Lebon, Guillaume ; Heydenreich, Franziska M. ; Flock, Tilman ; Miljus, Tamara ; Balaji, Santhanam ; Bouvier, Michel ; Veprintsev, Dmitry B. ; Tate, Christopher G. ; Schertler, Gebhard F. X. ; Babu, M. Madan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-08, Vol.536 (7617), p.484-487
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The structural basis of agonist-induced activation in constitutively active rhodopsin
Author / Creator:Standfuss, Jörg ; Edwards, Patricia C. ; D’Antona, Aaron ; Fransen, Maikel ; Xie, Guifu ; Oprian, Daniel D. ; Schertler, Gebhard F. X.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-03, Vol.471 (7340), p.656-660
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Structure of the µ-opioid receptor–Gi protein complex
Author / Creator:Koehl, Antoine ; Hu, Hongli ; Maeda, Shoji ; Zhang, Yan ; Qu, Qianhui ; Paggi, Joseph M. ; Latorraca, Naomi R. ; Hilger, Daniel ; Dawson, Roger ; Matile, Hugues ; Schertler, Gebhard F. X. ; Granier, Sebastien ; Weis, William I. ; Dror, Ron O. ; Manglik, Aashish ; Skiniotis, Georgios ; Kobilka, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-06, Vol.558 (7711), p.547-552
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Femtosecond-to-millisecond structural changes in a light-driven sodium pump
Author / Creator:Skopintsev, Petr ; Ehrenberg, David ; Weinert, Tobias ; James, Daniel ; Kar, Rajiv K. ; Johnson, Philip J. M. ; Ozerov, Dmitry ; Furrer, Antonia ; Martiel, Isabelle ; Dworkowski, Florian ; Nass, Karol ; Knopp, Gregor ; Cirelli, Claudio ; Arrell, Christopher ; Gashi, Dardan ; Mous, Sandra ; Wranik, Maximilian ; Gruhl, Thomas ; Kekilli, Demet ; Brünle, Steffen ; Deupi, Xavier ; Schertler, Gebhard F. X. ; Benoit, Roger M. ; Panneels, Valerie ; Nogly, Przemyslaw ; Schapiro, Igor ; Milne, Christopher ; Heberle, Joachim ; Standfuss, Jörg
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-07, Vol.583 (7815), p.314-318
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Development of an antibody fragment that stabilizes GPCR/G-protein complexes
Author / Creator:Maeda, Shoji ; Koehl, Antoine ; Matile, Hugues ; Hu, Hongli ; Hilger, Daniel ; Schertler, Gebhard F. X. ; Manglik, Aashish ; Skiniotis, Georgios ; Dawson, Roger J. P. ; Kobilka, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-09, Vol.9 (1), p.3712-9, Article 3712
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Molecular signatures of G-protein-coupled receptors
Author / Creator:Venkatakrishnan, A. J. ; Deupi, Xavier ; Lebon, Guillaume ; Tate, Christopher G. ; Schertler, Gebhard F. ; Babu, M. Madan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-02, Vol.494 (7436), p.185-194
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Tracking G-protein-coupled receptor activation using genetically encoded infrared probes
Author / Creator:Ye, Shixin ; Zaitseva, Ekaterina ; Caltabiano, Gianluigi ; Schertler, Gebhard F. X. ; Sakmar, Thomas P. ; Deupi, Xavier ; Vogel, Reiner
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-04, Vol.464 (7293), p.1386-1389
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Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation
Author / Creator:Mayer, Daniel ; Damberger, Fred F. ; Samarasimhareddy, Mamidi ; Feldmueller, Miki ; Vuckovic, Ziva ; Flock, Tilman ; Bauer, Brian ; Mutt, Eshita ; Zosel, Franziska ; Allain, Frédéric H. T. ; Standfuss, Jörg ; Schertler, Gebhard F. X. ; Deupi, Xavier ; Sommer, Martha E. ; Hurevich, Mattan ; Friedler, Assaf ; Veprintsev, Dmitry B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1261-1261, Article 1261
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Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Author / Creator:Rasmussen, Søren G. F. ; Choi, Hee-Jung ; Rosenbaum, Daniel M. ; Kobilka, Tong Sun ; Thian, Foon Sun ; Edwards, Patricia C. ; Burghammer, Manfred ; Ratnala, Venkata R. P. ; Sanishvili, Ruslan ; Fischetti, Robert F. ; Schertler, Gebhard F. X. ; Weis, William I. ; Kobilka, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2007-11, Vol.450 (7168), p.383-387
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ArticlesPeer ReviewedFull Text
The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
Author / Creator:Warne, Tony ; Moukhametzianov, Rouslan ; Baker, Jillian G. ; Nehmé, Rony ; Edwards, Patricia C. ; Leslie, Andrew G. W. ; Schertler, Gebhard F. X. ; Tate, Christopher G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-01, Vol.469 (7329), p.241-244
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The structure of the native CNGA1/CNGB1 CNG channel from bovine retinal rods
Author / Creator:Barret, Diane C. A. ; Schertler, Gebhard F. X. ; Kaupp, U. Benjamin ; Marino, Jacopo
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2022-01, Vol.29 (1), p.32-39
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ArticlesPeer ReviewedFull Text
Active state structures of a bistable visual opsin bound to G proteins
Author / Creator:Tejero, Oliver ; Pamula, Filip ; Koyanagi, Mitsumasa ; Nagata, Takashi ; Afanasyev, Pavel ; Das, Ishita ; Deupi, Xavier ; Sheves, Mordechai ; Terakita, Akihisa ; Schertler, Gebhard F. X. ; Rodrigues, Matthew J. ; Tsai, Ching-Ju
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8928-13, Article 8928
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ArticlesPeer ReviewedFull Text
Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR
Author / Creator:Varma, Niranjan ; Mutt, Eshita ; Mühle, Jonas ; Panneels, Valérie ; Terakita, Akihisa ; Deupi, Xavier ; Nogly, Przemyslaw ; Schertler, Gebhard F. X. ; Lesca, Elena
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (29), p.14547-14556
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ArticlesPeer ReviewedFull Text
Structure of a β1-adrenergic G-protein-coupled receptor
Author / Creator:Warne, Tony ; Serrano-Vega, Maria J. ; Baker, Jillian G. ; Moukhametzianov, Rouslan ; Edwards, Patricia C. ; Henderson, Richard ; Leslie, Andrew G. W. ; Tate, Christopher G. ; Schertler, Gebhard F. X.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2008-07, Vol.454 (7203), p.486-491
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The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor
Author / Creator:Miller-Gallacher, Jennifer L. ; Nehmé, Rony ; Warne, Tony ; Edwards, Patricia C. ; Schertler, Gebhard F. X. ; Leslie, Andrew G. W. ; Tate, Christopher G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-03, Vol.9 (3), p.e92727-e92727
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Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
Author / Creator:Benoit, Roger M. ; Frey, Daniel ; Hilbert, Manuel ; Kevenaar, Josta T. ; Wieser, Mara M. ; Stirnimann, Christian U. ; McMillan, David ; Ceska, Tom ; Lebon, Florence ; Jaussi, Rolf ; Steinmetz, Michel O. ; Schertler, Gebhard F. X. ; Hoogenraad, Casper C. ; Capitani, Guido ; Kammerer, Richard A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-01, Vol.505 (7481), p.108-111
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New Insights into Arrestin Recruitment to GPCRs
Author / Creator:Spillmann, Martin ; Thurner, Larissa ; Romantini, Nina ; Zimmermann, Mirjam ; Meger, Benoit ; Behe, Martin ; Waldhoer, Maria ; Schertler, Gebhard ; Berger, Philipp
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (14), p.4949
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High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs
Author / Creator:Wu, Na ; Olechwier, Agnieszka M. ; Brunner, Cyrill ; Edwards, Patricia C. ; Tsai, Ching-Ju ; Tate, Christopher G. ; Schertler, Gebhard F. X. ; Schneider, Gisbert ; Deupi, Xavier ; Zenobi, Renato ; Ma, Pikyee
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (31), p.1-9
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Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone
Author / Creator:Romantini, Nina ; Alam, Shahidul ; Dobitz, Stefanie ; Spillmann, Martin ; De Foresta, Martina ; Schibli, Roger ; Schertler, Gebhard F. X. ; Wennemers, Helma ; Deupi, Xavier ; Behe, Martin ; Berger, Philipp
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (48), p.1-8
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Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
Author / Creator:Nogly, Przemyslaw ; Weinert, Tobias ; James, Daniel ; Carbajo, Sergio ; Ozerov, Dmitry ; Furrer, Antonia ; Gashi, Dardan ; Borin, Veniamin ; Skopintsev, Petr ; Jaeger, Kathrin ; Nass, Karol ; Båth, Petra ; Bosman, Robert ; Koglin, Jason ; Seaberg, Matthew ; Lane, Thomas ; Kekilli, Demet ; Brünle, Steffen ; Tanaka, Tomoyuki ; Wu, Wenting ; Milne, Christopher ; White, Thomas ; Barty, Anton ; Weierstall, Uwe ; Panneels, Valerie ; Nango, Eriko ; Iwata, So ; Hunter, Mark ; Schapiro, Igor ; Schertler, Gebhard ; Neutze, Richard ; Standfuss, Jörg
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-07, Vol.361 (6398)
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Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

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The structural basis of agonist-induced activation in constitutively active rhodopsin

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Structure of the µ-opioid receptor–Gi protein complex

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Femtosecond-to-millisecond structural changes in a light-driven sodium pump

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Development of an antibody fragment that stabilizes GPCR/G-protein complexes

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Molecular signatures of G-protein-coupled receptors

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Tracking G-protein-coupled receptor activation using genetically encoded infrared probes

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Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

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Crystal structure of the human β2 adrenergic G-protein-coupled receptor

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The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

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The structure of the native CNGA1/CNGB1 CNG channel from bovine retinal rods

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Active state structures of a bistable visual opsin bound to G proteins

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Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

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Structure of a β1-adrenergic G-protein-coupled receptor

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The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

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Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

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New Insights into Arrestin Recruitment to GPCRs

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High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs

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Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone

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Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser

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