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Newsletter articlesFull Text
INTERNATIONAL PATENT: SCHMITT-ULMS, GEROLD, MEHRABIAN, MOHADESEH, WILLIAMS, DECLAN GWILLYM FILES APPLICATION FOR "COMPOUNDS FOR ALTERING LEVELS OF ONE OR MORE NKA ALPHA SUBUNITS AND THEIR USE IN TREAT...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2022
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ArticlesPeer ReviewedFull Text
Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases
Author / Creator:Arnould, Hélène ; Baudouin, Vincent ; Baudry, Anne ; Ribeiro, Luiz W. ; Ardila-Osorio, Hector ; Pietri, Mathéa ; Caradeuc, Cédric ; Soultawi, Cynthia ; Williams, Declan ; Alvarez, Marjorie ; Crozet, Carole ; Djouadi, Fatima ; Laforge, Mireille ; Bertho, Gildas ; Kellermann, Odile ; Launay, Jean-Marie ; Schmitt-Ulms, Gerold ; Schneider, Benoit
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2021-10, Vol.17 (10), p.e1009991-e1009991
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ArticlesPeer ReviewedFull Text
Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers
Author / Creator:Wang, Hansen ; Muiznieks, Lisa D ; Ghosh, Punam ; Williams, Declan ; Solarski, Michael ; Fang, Andrew ; Ruiz-Riquelme, Alejandro ; Pomès, Régis ; Watts, Joel C ; Chakrabartty, Avi ; Wille, Holger ; Sharpe, Simon ; Schmitt-Ulms, Gerold
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2017-06, Vol.6
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ArticlesPeer ReviewedFull Text
Proteome‐wide identification of mycobacterial pupylation targets
Author / Creator:Poulsen, Christian ; Akhter, Yusuf ; Jeon, Amy Hye‐Won ; Schmitt‐Ulms, Gerold ; Meyer, Helmut E ; Stefanski, Anja ; Stühler, Kai ; Wilmanns, Matthias ; Song, Young‐Hwa
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2010-07, Vol.6 (1), p.386-n/a
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ArticlesPeer ReviewedFull Text
The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections
Author / Creator:Watts, Joel C ; Drisaldi, Bettina ; Ng, Vivian ; Yang, Jing ; Strome, Bob ; Horne, Patrick ; Sy, Man-Sun ; Yoong, Larry ; Young, Rebecca ; Mastrangelo, Peter ; Bergeron, Catherine ; Fraser, Paul E ; Carlson, George A ; Mount, Howard TJ ; Schmitt-Ulms, Gerold ; Westaway, David
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2007-09, Vol.26 (17), p.4038-4050
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ArticlesPeer ReviewedFull Text
Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation
Author / Creator:Lau, Agnes ; McDonald, Alex ; Daude, Nathalie ; Mays, Charles E ; Walter, Eric D ; Aglietti, Robin ; Mercer, Robert CC ; Wohlgemuth, Serene ; van der Merwe, Jacques ; Yang, Jing ; Gapeshina, Hristina ; Kim, Chae ; Grams, Jennifer ; Shi, Beipei ; Wille, Holger ; Balachandran, Aru ; Schmitt‐Ulms, Gerold ; Safar, Jiri G ; Millhauser, Glenn L ; Westaway, David
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2015-03, Vol.7 (3), p.339-356
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ArticlesPeer ReviewedFull Text
Drug Repositioning for Alzheimer’s Disease Based on Systematic ‘omics’ Data Mining
Author / Creator:Zhang, Ming ; Schmitt-Ulms, Gerold ; Sato, Christine ; Xi, Zhengrui ; Zhang, Yalun ; Zhou, Ye ; St George-Hyslop, Peter ; Rogaeva, Ekaterina
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-12, Vol.11 (12), p.e0168812-e0168812
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ArticlesPeer ReviewedFull Text
The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis
Author / Creator:Mehrabian, Mohadeseh ; Brethour, Dylan ; Wang, Hansen ; Xi, Zhengrui ; Rogaeva, Ekaterina ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-08, Vol.10 (8), p.e0133741-e0133741
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ArticlesPeer ReviewedFull Text
Aggregation of Aβ40/42 chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations
Author / Creator:Wu, Min ; Dorosh, Lyudmyla ; Schmitt-Ulms, Gerold ; Wille, Holger ; Stepanova, Maria
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2021-03, Vol.17 (3), p.e1008771
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ArticlesPeer ReviewedFull Text
Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein
Author / Creator:Mehrabian, Mohadeseh ; Wang, Xinzhu ; Eid, Shehab ; Yan, Bei Qi ; Grinberg, Mark ; Siegner, Murdock ; Sackmann, Christopher ; Sulman, Muhammad ; Zhao, Wenda ; Williams, Declan ; Schmitt-Ulms, Gerold
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-07, Vol.17 (7), p.e0270915-e0270915
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ArticlesPeer ReviewedFull Text
The cellular prion protein interacts with and promotes the activity of Na,K-ATPases
Author / Creator:Williams, Declan ; Mehrabian, Mohadeseh ; Arshad, Hamza ; Eid, Shehab ; Sackmann, Christopher ; Zhao, Wenda ; Wang, Xinzhu ; Ghodrati, Farinaz ; Verkuyl, Claire E. ; Watts, Joel C. ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-11, Vol.16 (11), p.e0258682-e0258682
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ArticlesPeer ReviewedFull Text
The MEF2A transcription factor interactome in cardiomyocytes
Author / Creator:Moustafa, Amira ; Hashemi, Sara ; Brar, Gurnoor ; Grigull, Jörg ; Ng, Siemon H. S. ; Williams, Declan ; Schmitt-Ulms, Gerold ; McDermott, John C.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2023-04, Vol.14 (4), p.240-240, Article 240
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ArticlesPeer ReviewedFull Text
The human brain somatostatin interactome: SST binds selectively to P-type family ATPases
Author / Creator:Solarski, Michael ; Williams, Declan ; Mehrabian, Mohadeseh ; Wang, Hansen ; Wille, Holger ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-05, Vol.14 (5), p.e0217392-e0217392
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ArticlesPeer ReviewedFull Text
CRISPR-Cas9-Based Knockout of the Prion Protein and Its Effect on the Proteome
Author / Creator:Mehrabian, Mohadeseh ; Brethour, Dylan ; MacIsaac, Sarah ; Kim, Jin Kyu ; Gunawardana, C . Geeth ; Wang, Hansen ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e114594
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ArticlesPeer ReviewedFull Text
Evolutionary Descent of Prion Genes from the ZIP Family of Metal Ion Transporters
Author / Creator:Schmitt-Ulms, Gerold ; Ehsani, Sepehr ; Watts, Joel C. ; Westaway, David ; Wille, Holger
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-09, Vol.4 (9), p.e7208-e7208
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ArticlesPeer ReviewedFull Text
Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins
Author / Creator:Markham, Kelly ; Bai, Yu ; Schmitt-Ulms, Gerold
Publisher:Germany: Berlin/Heidelberg : Springer-Verlag
Journal title:Analytical and bioanalytical chemistry, 2007-09, Vol.389 (2), p.461-473
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ArticlesPeer ReviewedFull Text
Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue
Author / Creator:Mehrabian, Mohadeseh ; Brethour, Dylan ; Williams, Declan ; Wang, Hansen ; Arnould, Hélène ; Schneider, Benoit ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0156779-e0156779
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ArticlesPeer ReviewedFull Text
Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression
Author / Creator:Ruiz-Riquelme, Alejandro ; Lau, Heather H. C. ; Stuart, Erica ; Goczi, Adrienn N. ; Wang, Zhilan ; Schmitt-Ulms, Gerold ; Watts, Joel C.
Publisher:England: BioMed Central
Journal title:Acta neuropathologica communications, 2018-04, Vol.6 (1), p.26-26, Article 26
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ArticlesPeer ReviewedFull Text
Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones
Author / Creator:Watts, Joel C ; Huo, Hairu ; Bai, Yu ; Ehsani, Sepehr ; Jeon, Amy Hye Won ; Won, Amy Hye ; Shi, Tujin ; Daude, Nathalie ; Lau, Agnes ; Young, Rebecca ; Xu, Lei ; Carlson, George A ; Williams, David ; Westaway, David ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2009-10, Vol.5 (10), p.e1000608-e1000608
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ArticlesPeer ReviewedFull Text
Application of CRISPR genetic screens to investigate neurological diseases
Author / Creator:So, Raphaella W. L. ; Chung, Sai Wai ; Lau, Heather H. C. ; Watts, Jeremy J. ; Gaudette, Erin ; Al-Azzawi, Zaid A. M. ; Bishay, Jossana ; Lin, Lilian Tsai-Wei ; Joung, Julia ; Wang, Xinzhu ; Schmitt-Ulms, Gerold
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2019-11, Vol.14 (1), p.41-16, Article 41
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INTERNATIONAL PATENT: SCHMITT-ULMS, GEROLD, MEHRABIAN, MOHADESEH, WILLIAMS, DECLAN GWILLYM FILES APPLICATION FOR "COMPOUNDS FOR ALTERING LEVELS OF ONE OR MORE NKA ALPHA SUBUNITS AND THEIR USE IN TREAT...

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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases

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Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

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Proteome‐wide identification of mycobacterial pupylation targets

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The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections

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Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

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Drug Repositioning for Alzheimer’s Disease Based on Systematic ‘omics’ Data Mining

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The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

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Aggregation of Aβ40/42 chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations

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Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein

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The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

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The MEF2A transcription factor interactome in cardiomyocytes

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The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

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CRISPR-Cas9-Based Knockout of the Prion Protein and Its Effect on the Proteome

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Evolutionary Descent of Prion Genes from the ZIP Family of Metal Ion Transporters

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Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

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Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue

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Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

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Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

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Application of CRISPR genetic screens to investigate neurological diseases

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