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ArticlesPeer ReviewedFull Text
Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results
Author / Creator:Heuser, Michael ; Palmisiano, Neil ; Mantzaris, Ioannis ; Mims, Alice ; DiNardo, Courtney ; Silverman, Lewis R. ; Wang, Eunice S. ; Fiedler, Walter ; Baldus, Claudia ; Schwind, Sebastian ; Pardee, Timothy ; Perl, Alexander E. ; Cai, Charles ; Kaulfuss, Stefan ; Lagkadinou, Eleni ; Rentzsch, Christine ; Wagner, Markus ; Wilkinson, Gary ; Wu, Bingyan ; Jeffers, Michael ; Genvresse, Isabelle ; Krämer, Alwin
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-11, Vol.34 (11), p.2903-2913
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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine
Author / Creator:Blum, William ; Garzon, Ramiro ; Klisovic, Rebecca B ; Schwind, Sebastian ; Walker, Alison ; Geyer, Susan ; Liu, Shujun ; Havelange, Violaine ; Becker, Heiko ; Schaaf, Larry ; Mickle, Jon ; Devine, Hollie ; Kefauver, Cheryl ; Devine, Steven M ; Chan, Kenneth K ; Heerema, Nyla A ; Bloomfield, Clara D ; Grever, Michael R ; Byrd, John C ; Villalona-Calero, Miguel ; Croce, Carlo M ; Marcucci, Guido
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7473-7478
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Prognostic impact of the AML ELN2022 risk classification in patients undergoing allogeneic stem cell transplantation
Author / Creator:Jentzsch, Madlen ; Bischof, Lara ; Ussmann, Jule ; Backhaus, Donata ; Brauer, Dominic ; Metzeler, Klaus H. ; Merz, Maximilian ; Vucinic, Vladan ; Franke, Georg-Nikolaus ; Herling, Marco ; Platzbecker, Uwe ; Schwind, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2022-12, Vol.12 (12), p.170-10, Article 170
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Compartment-specific mutational landscape of clonal hematopoiesis
Author / Creator:Hartmann, Luise ; Hecker, Judith S. ; Rothenberg-Thurley, Maja ; Rivière, Jennifer ; Jentzsch, Madlen ; Ksienzyk, Bianka ; Buck, Michèle C. ; van der Garde, Mark ; Fischer, Luise ; Winter, Susann ; Rauner, Martina ; Tsourdi, Elena ; Weidner, Heike ; Sockel, Katja ; Schneider, Marie ; Kubasch, Anne S. ; Nolde, Martin ; Hausmann, Dominikus ; Lützner, Jörg ; Goralski, Szymon ; Bassermann, Florian ; Spiekermann, Karsten ; Hofbauer, Lorenz C. ; Schwind, Sebastian ; Platzbecker, Uwe ; Götze, Katharina S. ; Metzeler, Klaus H.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-11, Vol.36 (11), p.2647-2655
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Disruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation
Author / Creator:Wurm, Alexander Arthur ; Zjablovskaja, Polina ; Kardosova, Miroslava ; Gerloff, Dennis ; Bräuer-Hartmann, Daniela ; Katzerke, Christiane ; Hartmann, Jens-Uwe ; Benoukraf, Touati ; Fricke, Stephan ; Hilger, Nadja ; Müller, Anne-Marie ; Bill, Marius ; Schwind, Sebastian ; Tenen, Daniel G. ; Niederwieser, Dietger ; Alberich-Jorda, Meritxell ; Behre, Gerhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-06, Vol.8 (1), p.46-46, Article 46
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Prognostic relevance of remission and measurable residual disease status in AML patients prior to reduced intensity or non-myeloablative allogeneic stem cell transplantation
Author / Creator:Jentzsch, Madlen ; Grimm, Juliane ; Bill, Marius ; Brauer, Dominic ; Backhaus, Donata ; Schulz, Julia ; Goldmann, Karoline ; Niederwieser, Dietger ; Platzbecker, Uwe ; Schwind, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2021-04, Vol.11 (4), p.80-80, Article 80
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Quantifying NPM1 MRD in AML patients prior to allogeneic stem cell transplantation: Where to draw the line?
Author / Creator:Schwind, Sebastian ; Bischof, Lara ; Bill, Marius ; Grimm, Juliane ; Ussmann, Jule ; Backhaus, Donata ; Brauer, Dominic ; Thanh, Tung Pham ; Merz, Maximilian ; Franke, Georg‐Nikolaus ; Metzeler, Klaus H. ; Vucinic, Vladan ; Herling, Marco ; Platzbecker, Uwe ; Jentzsch, Madlen
Publisher:United States: John Wiley & Sons, Inc
Journal title:HemaSphere, 2024-03, Vol.8 (3), p.e55-n/a
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ArticlesPeer ReviewedFull Text
NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation
Author / Creator:Eisfeld, Ann-Kathrin ; Schwind, Sebastian ; Hoag, Kevin W. ; Walker, Cristopher J. ; Liyanarachchi, Sandya ; Patel, Ravi ; Huang, Xiaomeng ; Markowitz, Joseph ; Duan, Wenrui ; Otterson, Gregory A. ; Carson, William E. ; Marcucci, Guido ; Bloomfield, Clara D. ; de la Chapelle, Albert
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4179-4184
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Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia
Author / Creator:Eisfeld, Ann-Kathrin ; Marcucci, Guido ; Liyanarachchi, Sandya ; Döhner, Konstanze ; Schwind, Sebastian ; Maharry, Kati ; Leffel, Benjamin ; Döhner, Hartmut ; Radmacher, Michael D ; Bloomfield, Clara D ; Tanner, Stephan M ; de la Chapelle, Albert
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6668-6673
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Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia
Author / Creator:Zhao, Xi ; Huang, Xiaomeng ; Wang, Xinmei ; Wu, Yun ; Eisfeld, Ann‐Kathrin ; Schwind, Sebastian ; Gallego‐Perez, Daniel ; Boukany, Pouyan E. ; Marcucci, Guido I. ; Lee, Ly James
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2015-12, Vol.2 (12), p.1500111-n/a
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ArticlesPeer ReviewedFull Text
Methods for high-throughput MethylCap-Seq data analysis
Author / Creator:Rodriguez, Benjamin AT ; Frankhouser, David ; Murphy, Mark ; Trimarchi, Michael ; Tam, Hok-Hei ; Curfman, John ; Huang, Rita ; Chan, Michael WY ; Lai, Hung-Cheng ; Parikh, Deval ; Ball, Bryan ; Schwind, Sebastian ; Blum, William ; Marcucci, Guido ; Yan, Pearlly ; Bundschuh, Ralf
Publisher:England: BioMed Central
Journal title:BMC genomics, 2012-10, Vol.13 (S6), p.S14-S14, Article S14
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A high hematopoietic cell transplantation comorbidity Index (HCT-CI) does not impair outcomes after non-myeloablative allogeneic stem cell transplantation in acute myeloid leukemia patients 60 years o...
Author / Creator:Backhaus, Donata ; Brauer, Dominic ; Pointner, Rosmarie ; Bischof, Lara ; Vucinic, Vladan ; Franke, Georg-Nikolaus ; Niederwieser, Dietger ; Platzbecker, Uwe ; Jentzsch, Madlen ; Schwind, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2023-01, Vol.58 (1), p.30-38
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ELN risk stratification and outcomes in secondary and therapy-related AML patients consolidated with allogeneic stem cell transplantation
Author / Creator:Jentzsch, Madlen ; Grimm, Juliane ; Bill, Marius ; Brauer, Dominic ; Backhaus, Donata ; Goldmann, Karoline ; Schulz, Julia ; Niederwieser, Dietger ; Platzbecker, Uwe ; Schwind, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2021-04, Vol.56 (4), p.936-945
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MicroRNA Expression Patterns Reveal a Role of the TGF-β Family Signaling in AML Chemo-Resistance
Author / Creator:Reichelt, Paula ; Bernhart, Stephan ; Wilke, Franziska ; Schwind, Sebastian ; Cross, Michael ; Platzbecker, Uwe ; Behre, Gerhard
Publisher:Basel: MDPI AG
Journal title:Cancers, 2023-10, Vol.15 (20), p.5086
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Prognostic impact of measurable residual clonal hematopoiesis in acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation
Author / Creator:Bischof, Lara ; Ussmann, Jule ; Grimm, Juliane ; Bill, Marius ; Brauer, Dominic ; Backhaus, Donata ; Herrmann, Lisa ; Merz, Maximilian ; Herling, Marco ; Metzeler, Klaus H. ; Franke, Georg-Nikolaus ; Vucinic, Vladan ; Platzbecker, Uwe ; Schwind, Sebastian ; Jentzsch, Madlen
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2024-01, Vol.38 (1), p.198-201
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Cellular dynamics following CAR T cell therapy are associated with response and toxicity in relapsed/refractory myeloma
Author / Creator:Fischer, Luise ; Grieb, Nora ; Born, Patrick ; Weiss, Ronald ; Seiffert, Sabine ; Boldt, Andreas ; Fricke, Stephan ; Franz, Paul ; Heyn, Simone ; Kubasch, Anne Sophie ; Baber, Ronny ; Weidner, Heike ; Wang, Song Yau ; Bach, Enrica ; Hoffmann, Sandra ; Ussmann, Jule ; Kirchberg, Janine ; Hell, Saskia ; Schwind, Sebastian ; Metzeler, Klaus H. ; Herling, Marco ; Jentzsch, Madlen ; Franke, Georg-Nikolaus ; Sack, Ulrich ; Reiche, Kristin ; Köhl, Ulrike ; Platzbecker, Uwe ; Vucinic, Vladan ; Merz, Maximilian
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2024-02, Vol.38 (2), p.372-382
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Digital droplet PCR-based absolute quantification of pre-transplant NPM1 mutation burden predicts relapse in acute myeloid leukemia patients
Author / Creator:Bill, Marius ; Grimm, Juliane ; Jentzsch, Madlen ; Kloss, Laura ; Goldmann, Karoline ; Schulz, Julia ; Beinicke, Stefanie ; Häntschel, Janine ; Cross, Michael ; Vucinic, Vladan ; Pönisch, Wolfram ; Behre, Gerhard ; Franke, Georg-Nikolaus ; Lange, Thoralf ; Niederwieser, Dietger ; Schwind, Sebastian
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2018-10, Vol.97 (10), p.1757-1765
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Prognostic value of baseline and early response FDG-PET/CT in patients with refractory and relapsed aggressive B-cell lymphoma undergoing CAR-T cell therapy
Author / Creator:Georgi, Thomas Walter ; Kurch, Lars ; Franke, Georg-Nikolaus ; Jentzsch, Madlen ; Schwind, Sebastian ; Perez-Fernandez, Carmen ; Petermann, Naima ; Merz, Maximilian ; Metzeler, Klaus ; Borte, Gudrun ; Hoffmann, Sandra ; Herling, Marco ; Denecke, Timm ; Kluge, Regine ; Sabri, Osama ; Platzbecker, Uwe ; Vučinić, Vladan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2023-08, Vol.149 (9), p.6131-6138
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Clinical Challenges and Consequences of Measurable Residual Disease in Non-APL Acute Myeloid Leukemia
Author / Creator:Jentzsch, Madlen ; Schwind, Sebastian ; Bach, Enrica ; Stasik, Sebastian ; Thiede, Christian ; Platzbecker, Uwe
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-10, Vol.11 (11), p.1625
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Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation
Author / Creator:Grimm, Juliane ; Bill, Marius ; Jentzsch, Madlen ; Beinicke, Stefanie ; Häntschel, Janine ; Goldmann, Karoline ; Schulz, Julia ; Cross, Michael ; Franke, Georg–Nikolaus ; Behre, Gerhard ; Vucinic, Vladan ; Pönisch, Wolfram ; Lange, Thoralf ; Niederwieser, Dietger ; Schwind, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2019-08, Vol.54 (8), p.1189-1197
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Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results

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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine

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Prognostic impact of the AML ELN2022 risk classification in patients undergoing allogeneic stem cell transplantation

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Compartment-specific mutational landscape of clonal hematopoiesis

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Disruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation

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Prognostic relevance of remission and measurable residual disease status in AML patients prior to reduced intensity or non-myeloablative allogeneic stem cell transplantation

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Quantifying NPM1 MRD in AML patients prior to allogeneic stem cell transplantation: Where to draw the line?

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NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation

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Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia

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Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia

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Methods for high-throughput MethylCap-Seq data analysis

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A high hematopoietic cell transplantation comorbidity Index (HCT-CI) does not impair outcomes after non-myeloablative allogeneic stem cell transplantation in acute myeloid leukemia patients 60 years o...

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ELN risk stratification and outcomes in secondary and therapy-related AML patients consolidated with allogeneic stem cell transplantation

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MicroRNA Expression Patterns Reveal a Role of the TGF-β Family Signaling in AML Chemo-Resistance

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Prognostic impact of measurable residual clonal hematopoiesis in acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation

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Cellular dynamics following CAR T cell therapy are associated with response and toxicity in relapsed/refractory myeloma

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Digital droplet PCR-based absolute quantification of pre-transplant NPM1 mutation burden predicts relapse in acute myeloid leukemia patients

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Prognostic value of baseline and early response FDG-PET/CT in patients with refractory and relapsed aggressive B-cell lymphoma undergoing CAR-T cell therapy

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Clinical Challenges and Consequences of Measurable Residual Disease in Non-APL Acute Myeloid Leukemia

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Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation

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