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Human CD8+ EMRA T cells display a senescence‐associated secretory phenotype regulated by p38 MAPK
Author / Creator:Callender, Lauren A. ; Carroll, Elizabeth C. ; Beal, Robert W. J. ; Chambers, Emma S. ; Nourshargh, Sussan ; Akbar, Arne N. ; Henson, Sian M.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2018-02, Vol.17 (1), p.n/a
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Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
Author / Creator:Chambers, Cecilia R. ; Ritchie, Shona ; Pereira, Brooke A. ; Timpson, Paul
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2021-12, Vol.15 (12), p.3242-3255
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IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype
Author / Creator:Wiggins, Kimberley A. ; Parry, Aled J. ; Cassidy, Liam D. ; Humphry, Melanie ; Webster, Steve J. ; Goodall, Jane C. ; Narita, Masashi ; Clarke, Murray C. H.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-06, Vol.18 (3), p.e12946-n/a
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The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?
Author / Creator:Ohtani, Naoko
Publisher:England: BioMed Central
Journal title:Inflammation and regeneration, 2022-04, Vol.42 (1), p.11
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Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κB activation
Author / Creator:Moiseeva, Olga ; Deschênes‐Simard, Xavier ; St‐Germain, Emmanuelle ; Igelmann, Sebastian ; Huot, Geneviève ; Cadar, Alexandra E. ; Bourdeau, Véronique ; Pollak, Michael N. ; Ferbeyre, Gerardo
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2013-06, Vol.12 (3), p.489-498
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Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer
Author / Creator:Loo, Tze Mun ; Miyata, Kenichi ; Tanaka, Yoko ; Takahashi, Akiko
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-02, Vol.111 (2), p.304-311
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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
Author / Creator:Watanabe, Sugiko ; Kawamoto, Shimpei ; Ohtani, Naoko ; Hara, Eiji
Publisher:England: John Wiley and Sons Inc
Journal title:Cancer science, 2017-04, Vol.108 (4), p.563-569
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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
Author / Creator:Laberge, Remi-Martin ; Sun, Yu ; Orjalo, Arturo V. ; Patil, Christopher K. ; Freund, Adam ; Zhou, Lili ; Curran, Samuel C. ; Davalos, Albert R. ; Wilson-Edell, Kathleen A. ; Liu, Su ; Limbad, Chandani ; Demaria, Marco ; Li, Patrick ; Hubbard, Gene B. ; Ikeno, Yuji ; Javors, Martin ; Desprez, Pierre-Yves ; Benz, Christopher C. ; Kapahi, Pankaj ; Nelson, Peter S. ; Campisi, Judith
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-08, Vol.17 (8), p.1049-1061
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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Author / Creator:Xu, Ming ; Tchkonia, Tamara ; Ding, Husheng ; Ogrodnik, Mikolaj ; Lubbers, Ellen R. ; Pirtskhalava, Tamar ; White, Thomas A. ; Johnson, Kurt O. ; Stout, Michael B. ; Mezera, Vojtech ; Giorgadze, Nino ; Jensen, Michael D. ; LeBrasseur, Nathan K. ; Kirkland, James L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.E6301-E6310
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“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes
Author / Creator:Olivieri, Fabiola ; Procopio, Antonio Domenico ; La Sala, Lucia ; De Nigris, Valeria ; Prattichizzo, Francesco ; Ceriello, Antonio
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-10
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mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
Author / Creator:Herranz, Nicolás ; Gallage, Suchira ; Mellone, Massimiliano ; Wuestefeld, Torsten ; Klotz, Sabrina ; Hanley, Christopher J. ; Raguz, Selina ; Acosta, Juan Carlos ; Innes, Andrew J. ; Banito, Ana ; Georgilis, Athena ; Montoya, Alex ; Wolter, Katharina ; Dharmalingam, Gopuraja ; Faull, Peter ; Carroll, Thomas ; Martínez-Barbera, Juan Pedro ; Cutillas, Pedro ; Reisinger, Florian ; Heikenwalder, Mathias ; Miller, Richard A. ; Withers, Dominic ; Zender, Lars ; Thomas, Gareth J. ; Gil, Jesús
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-09, Vol.17 (9), p.1205-1217
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p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
Author / Creator:Freund, Adam ; Patil, Christopher K ; Campisi, Judith
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2011-04, Vol.30 (8), p.1536-1548
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Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-[kappa]B activation
Author / Creator:Moiseeva, Olga ; Deschênes-Simard, Xavier ; St-Germain, Emmanuelle ; Igelmann, Sebastian ; Huot, Geneviève ; Cadar, Alexandra E ; Bourdeau, Véronique ; Pollak, Michael N ; Ferbeyre, Gerardo
Publisher:London: John Wiley & Sons, Inc
Journal title:Aging cell, 2013-06, Vol.12 (3), p.489
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Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
Author / Creator:Wiley, Christopher D. ; Schaum, Nicholas ; Alimirah, Fatouma ; Lopez-Dominguez, Jose Alberto ; Orjalo, Arturo V. ; Scott, Gary ; Desprez, Pierre-Yves ; Benz, Christopher ; Davalos, Albert R. ; Campisi, Judith
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.2410-9, Article 2410
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The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1
Author / Creator:Zhang, Boyi ; Fu, Da ; Xu, Qixia ; Cong, Xianling ; Wu, Chunyan ; Zhong, Xiaoming ; Ma, Yushui ; Lv, Zhongwei ; Chen, Fei ; Liu, Han ; Qian, Min ; Chin, Y Eugene ; Lam, Eric W -F ; Chiao, Paul ; Sun, Yu
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-04, Vol.9, p.1-19
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Cell senescence, the senescence-associated secretory phenotype, and cancers
Author / Creator:Langhi Prata, Larissa G. P. ; Tchkonia, Tamar ; Kirkland, James L.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2023-09, Vol.21 (9), p.e3002326
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Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype
Author / Creator:Torres-Querol, Coral ; Torres, Pascual ; Vidal, Noemí ; Portero-Otín, Manel ; Arque, Gloria ; Purroy, Francisco
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-08, Vol.11 (1), p.15752-9, Article 15752
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Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype
Author / Creator:Cougnoux, Antony ; Dalmasso, Guillaume ; Martinez, Ruben ; Buc, Emmanuel ; Delmas, Julien ; Gibold, Lucie ; Sauvanet, Pierre ; Darcha, Claude ; Déchelotte, Pierre ; Bonnet, Mathilde ; Pezet, Denis ; Wodrich, Harald ; Darfeuille-Michaud, Arlette ; Bonnet, Richard
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2014-12, Vol.63 (12), p.1932-1942
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Persistent epigenetic signals propel a senescence-associated secretory phenotype and trained innate immunity in CD34+ hematopoietic stem cells from diabetic patients
Author / Creator:Vinci, Maria Cristina ; Costantino, Sarah ; Damiano, Giulia ; Rurali, Erica ; Rinaldi, Raffaella ; Vigorelli, Vera ; Sforza, Annalisa ; Carulli, Ermes ; Pirola, Sergio ; Mastroiacovo, Giorgio ; Raucci, Angela ; El-Osta, Assam ; Paneni, Francesco ; Pompilio, Giulio
Publisher:England: BioMed Central
Journal title:Cardiovascular diabetology, 2024-03, Vol.23 (1), p.107-15, Article 107
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Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
Author / Creator:Barinda, Agian Jeffilano ; Ikeda, Koji ; Nugroho, Dhite Bayu ; Wardhana, Donytra Arby ; Sasaki, Naoto ; Honda, Sakiko ; Urata, Ryota ; Matoba, Satoaki ; Hirata, Ken-ichi ; Emoto, Noriaki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.481-13, Article 481
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Showing 1 to 20 of 1,859 results

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Human CD8+ EMRA T cells display a senescence‐associated secretory phenotype regulated by p38 MAPK

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Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer

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IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype

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The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?

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Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κB activation

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Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer

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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases

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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

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“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes

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mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

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p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

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Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-[kappa]B activation

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Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

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The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

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Cell senescence, the senescence-associated secretory phenotype, and cancers

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Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype

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Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype

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Persistent epigenetic signals propel a senescence-associated secretory phenotype and trained innate immunity in CD34+ hematopoietic stem cells from diabetic patients

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Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype

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