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15 results for Shireby,+Gemma

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ArticlesPeer ReviewedFull Text
A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
Author / Creator:Smith, Rebecca G. ; Pishva, Ehsan ; Shireby, Gemma ; Smith, Adam R. ; Roubroeks, Janou A. Y. ; Hannon, Eilis ; Wheildon, Gregory ; Mastroeni, Diego ; Gasparoni, Gilles ; Riemenschneider, Matthias ; Giese, Armin ; Sharp, Andrew J. ; Schalkwyk, Leonard ; Haroutunian, Vahram ; Viechtbauer, Wolfgang ; van den Hove, Daniel L. A. ; Weedon, Michael ; Brokaw, Danielle ; Francis, Paul T. ; Thomas, Alan J. ; Love, Seth ; Morgan, Kevin ; Walter, Jörn ; Coleman, Paul D. ; Bennett, David A. ; De Jager, Philip L. ; Mill, Jonathan ; Lunnon, Katie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3517-3517, Article 3517
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ArticlesPeer ReviewedFull Text
DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
Author / Creator:Shireby, Gemma ; Dempster, Emma L. ; Policicchio, Stefania ; Smith, Rebecca G. ; Pishva, Ehsan ; Chioza, Barry ; Davies, Jonathan P. ; Burrage, Joe ; Lunnon, Katie ; Seiler Vellame, Dorothea ; Love, Seth ; Thomas, Alan ; Brookes, Keeley ; Morgan, Kevin ; Francis, Paul ; Hannon, Eilis ; Mill, Jonathan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-09, Vol.13 (1), p.5620-5620, Article 5620
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ArticlesPeer ReviewedFull Text
Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology
Author / Creator:Pihlstrøm, Lasse ; Shireby, Gemma ; Geut, Hanneke ; Henriksen, Sandra Pilar ; Rozemuller, Annemieke J. M. ; Tunold, Jon-Anders ; Hannon, Eilis ; Francis, Paul ; Thomas, Alan J. ; Love, Seth ; Mill, Jonathan ; van de Berg, Wilma D. J. ; Toft, Mathias
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4932-10, Article 4932
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Epigenome-wide association study of attention-deficit/hyperactivity disorder in adults
Author / Creator:Rovira, Paula ; Sánchez-Mora, Cristina ; Pagerols, Mireia ; Richarte, Vanesa ; Corrales, Montserrat ; Fadeuilhe, Christian ; Vilar-Ribó, Laura ; Arribas, Lorena ; Shireby, Gemma ; Hannon, Eilis ; Mill, Jonathan ; Casas, Miquel ; Ramos-Quiroga, Josep Antoni ; Soler Artigas, María ; Ribasés, Marta
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2020-06, Vol.10 (1), p.199-199, Article 199
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ArticlesPeer ReviewedFull Text
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Author / Creator:Steg, Leonard C. ; Shireby, Gemma L. ; Imm, Jennifer ; Davies, Jonathan P. ; Franklin, Alice ; Flynn, Robert ; Namboori, Seema C. ; Bhinge, Akshay ; Jeffries, Aaron R. ; Burrage, Joe ; Neilson, Grant W. A. ; Walker, Emma M. ; Perfect, Leo W. ; Price, Jack ; McAlonan, Grainne ; Srivastava, Deepak P. ; Bray, Nicholas J. ; Cope, Emma L. ; Jones, Kimberley M. ; Allen, Nicholas D. ; Pishva, Ehsan ; Dempster, Emma L. ; Lunnon, Katie ; Mill, Jonathan ; Hannon, Eilis
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2021-06, Vol.14 (1), p.98-98, Article 98
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ArticlesPeer ReviewedFull Text
Machine learning-based prediction of cognitive outcomes in de novo Parkinson’s disease
Author / Creator:Harvey, Joshua ; Reijnders, Rick A. ; Cavill, Rachel ; Duits, Annelien ; Köhler, Sebastian ; Eijssen, Lars ; Rutten, Bart P. F. ; Shireby, Gemma ; Torkamani, Ali ; Creese, Byron ; Leentjens, Albert F. G. ; Lunnon, Katie ; Pishva, Ehsan
Publisher:London: Nature Publishing Group UK
Journal title:NPJ Parkinson's Disease, 2022-11, Vol.8 (1), p.150-150, Article 150
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Dissertations & ThesesFull Text
Regulatory Genomic Consequences of Polygenic Risk Burden for Alzheimer’s Disease
Author / Creator:Shireby, Gemma
Publisher:ProQuest Dissertations & Theses
Date:2021
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ArticlesPeer ReviewedFull Text
Blood‐based multivariate methylation risk score for cognitive impairment and dementia
Author / Creator:Koetsier, Jarno ; Cavill, Rachel ; Reijnders, Rick ; Harvey, Joshua ; Homann, Jan ; Kouhsar, Morteza ; Deckers, Kay ; Köhler, Sebastian ; Eijssen, Lars M. T. ; den Hove, Daniel L. A. ; Demuth, Ilja ; Düzel, Sandra ; Smith, Rebecca G. ; Smith, Adam R. ; Burrage, Joe ; Walker, Emma M. ; Shireby, Gemma ; Hannon, Eilis ; Dempster, Emma ; Frayling, Tim ; Mill, Jonathan ; Dobricic, Valerija ; Johannsen, Peter ; Wittig, Michael ; Franke, Andre ; Vandenberghe, Rik ; Schaeverbeke, Jolien ; Freund‐Levi, Yvonne ; Frölich, Lutz ; Scheltens, Philip ; Teunissen, Charlotte E. ; Frisoni, Giovanni ; Blin, Olivier ; Richardson, Jill C. ; Bordet, Régis ; Engelborghs, Sebastiaan ; Roeck, Ellen ; Martinez‐Lage, Pablo ; Tainta, Mikel ; Lleó, Alberto ; Sala, Isabel ; Popp, Julius ; Peyratout, Gwendoline ; Verhey, Frans ; Tsolaki, Magda ; Andreasson, Ulf ; Blennow, Kaj ; Zetterberg, Henrik ; Streffer, Johannes ; Vos, Stephanie J. B. ; Lovestone, Simon ; Visser, Pieter‐Jelle ; Lill, Christina M. ; Bertram, Lars ; Lunnon, Katie ; Pishva, Ehsan
Publisher:United States: Alzheimer's Association / Wiley
Journal title:Alzheimer's & dementia, 2024-10, Vol.20 (10), p.6682-6698
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ArticlesPeer ReviewedFull Text
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021)
Author / Creator:van, Rheenen W ; van, der Spek RAA ; Bakker, MK ; van, Vugt JJFA ; Hop, PJ ; Zwamborn, RAJ ; de, Klein N ; Westra, H-J ; Bakker, OB ; Deelen, P
Journal title:NATURE GENETICS, 2022-03, Vol.54 (3), p.361
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ArticlesPeer ReviewedFull Text
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Author / Creator:van Rheenen, Wouter ; van der Spek, Rick a A ; Bakker, Mark K ; van Vugt, Joke J F A ; Hop, Paul J ; Zwamborn, Ramona a J ; de Klein, Niek ; Westra, Harm-Jan ; Bakker, Olivier B ; Deelen, Patrick ; Shireby, Gemma ; Hannon, Eilis ; Moisse, Matthieu ; Baird, Denis ; Restuadi, Restuadi ; Dolzhenko, Egor ; Dekker, Annelot M ; Gawor, Klara ; Westeneng, Henk-Jan ; Tazelaar, Gijs H P ; van Eijk, Kristel R ; Kooyman, Maarten ; Byrne, Ross P ; Doherty, Mark ; Heverin, Mark ; Al Khleifat, Ahmad ; Iacoangeli, Alfredo ; Shatunov, Aleksey ; Ticozzi, Nicola ; Cooper-Knock, Johnathan ; Smith, Bradley N ; Gromicho, Marta ; Chandran, Siddharthan ; Pal, Suvankar ; Morrison, Karen E ; Shaw, Pamela J ; Hardy, John ; Orrell, Richard W ; Sendtner, Michael ; Meyer, Thomas ; Başak, Nazli ; van der Kooi, Anneke J ; Ratti, Antonia ; Fogh, Isabella ; Gellera, Cinzia ; Lauria, Giuseppe ; Corti, Stefania ; Cereda, Cristina ; Sproviero, Daisy ; d'Alfonso, Sandra ; Sorarù, Gianni ; Siciliano, Gabriele ; Filosto, Massimiliano ; Padovani, Alessandro ; Chiò, Adriano ; Calvo, Andrea ; Moglia, Cristina ; Brunetti, Maura ; Canosa, Antonio ; Grassano, Maurizio ; Beghi, Ettore ; Pupillo, Elisabetta ; Logroscino, Giancarlo ; Nefussy, Beatrice ; Osmanovic, Alma ; Nordin, Angelica ; Lerner, Yossef ; Zabari, Michal ; Gotkine, Marc ; Baloh, Robert H ; Bell, Shaughn ; Vourc'H, Patrick ; Corcia, Philippe ; Couratier, Philippe ; Millecamps, Stéphanie ; Meininger, Vincent ; Salachas, François ; Mora Pardina, Jesus S ; Assialioui, Abdelilah ; Rojas-García, Ricardo ; Dion, Patrick A ; Ross, Jay P ; Ludolph, Albert C ; Weishaupt, Jochen H ; Brenner, David ; Freischmidt, Axel ; Bensimon, Gilbert ; Brice, Alexis ; Durr, Alexandra ; Payan, Christine a M ; Saker-Delye, Safa ; Wood, Nicholas W ; Topp, Simon ; Rademakers, Rosa ; Tittmann, Lukas ; Lieb, Wolfgang ; Franke, Andre ; Ripke, Stephan ; Braun, Alice ; Kraft, Julia
Publisher:Nature Publishing Group
Journal title:Nature genetics, 2022-03, Vol.54 (3)
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ArticlesFull Text
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Author / Creator:Steg, Leonard C ; Shireby, Gemma L ; Imm, Jennifer ; Davies, Jonathan P ; Franklin, Alice ; Flynn, Robert ; Namboori, Seema C ; Bhinge, Akshay ; Jeffries, Aaron R ; Burrage, Joe ; Neilson, Grant W A ; Walker, Emma M ; Perfect, Leo W ; Price, Jack ; Mcalonan, Grainne ; Srivastava, Deepak P ; Bray, Nicholas J ; Cope, Emma L ; Jones, Kimberly M ; Allen, Nicholas D ; Pishva, Ehsan ; Dempster, Emma L ; Lunnon, Katie ; Mill, Jonathan ; Hannon, Eilis
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-05
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ArticlesFull Text
A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens
Author / Creator:Stevenson, Anna J ; Mccartney, Daniel L ; Shireby, Gemma L ; Hillary, Robert F ; King, Declan ; Makis Tzioras ; Wrobel, Nicola ; Mccafferty, Sarah ; Murphy, Lee ; Mccoll, Barry W ; Redmond, Paul ; Taylor, Adele M ; Harris, Sarah E ; Russ, Tom C ; Hannon, Eilis J ; Mcintosh, Andrew M ; Mill, Jonathan ; Smith, Colin ; Deary, Ian J ; Cox, Simon R ; Marioni, Riccardo E ; Spires-Jones, Tara L
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-12
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ArticlesFull Text
Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays
Author / Creator:Flynn, Robert ; Washer, Sam ; Jeffries, Aaron R ; Andrayas, Alexandria ; Shireby, Gemma ; Kumari, Meena ; Schalkwyk, Leonard C ; Mill, Jonathan ; Hannon, Eilis
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-03
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ArticlesFull Text
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
Author / Creator:Shireby, Gemma ; Dempster, Emma ; Policicchio, Stefania ; Smith, Rebecca ; Pishva, Ehsan ; Chioza, Barry ; Davies, Jonathan ; Burrage, Joe ; Lunnon, Katie ; Seiler-Vellame, Dorothea ; Love, Seth ; Thomas, Alan ; Brookes, Keeley ; Morgan, Kevin ; Francis, Paul ; Hannon, Eilis ; Mill, Jonathan
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-03
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ArticlesFull Text
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex
Author / Creator:Smith, Rebecca ; Pishva, Ehsan ; Shireby, Gemma ; Smith, Adam R ; Janou Ay Roubroeks ; Hannon, Eilis ; Wheildon, Gregory ; Mastroeni, Diego ; Gasparoni, Gilles ; Riemenschneider, Matthias ; Giese, Armin ; Sharp, Andrew James ; Schalkwyk, Leonard C ; Haroutunian, Vahram ; Viechtbauer, Wolfgang ; Van Den Hove, Daniel ; Weedon, Michael N ; Brokaw, Danielle ; Francis, Paul T ; Thomas, Alan J ; Love, Seth ; Morgan, Kevin ; Walter, Jorn ; Coleman, Paul D ; Bennett, David A ; De Jager, Phillip ; Mill, Jonathan ; Lunnon, Katie
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-04
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A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

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DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

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Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology

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Epigenome-wide association study of attention-deficit/hyperactivity disorder in adults

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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

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Machine learning-based prediction of cognitive outcomes in de novo Parkinson’s disease

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Regulatory Genomic Consequences of Polygenic Risk Burden for Alzheimer’s Disease

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Blood‐based multivariate methylation risk score for cognitive impairment and dementia

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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021)

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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

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A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens

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Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays

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DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

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A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex

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