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ArticlesPeer ReviewedFull Text
Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
Author / Creator:Feng, Huichen ; Shuda, Masahiro ; Chang, Yuan ; Moore, Patrick S
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-02, Vol.319 (5866), p.1096-1100
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Merkel cell polyomavirus small T antigen is a viral transcription activator that is essential for viral genome maintenance
Author / Creator:Rapchak, Kyle ; Yagobian, Shiva D. ; Moore, Jackson ; Khattri, Michelle ; Shuda, Masahiro
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-12, Vol.18 (12), p.e1011039
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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus
Author / Creator:Shuda, Masahiro ; Feng, Huichen ; Kwun, Hyun Jin ; Rosen, Steven T ; Gjoerup, Ole ; Moore, Patrick S ; Chang, Yuan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16272-16277
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CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation
Author / Creator:Shuda, Masahiro ; Velásquez, Celestino ; Cheng, Erdong ; Cordek, Daniel G. ; Kwun, Hyun Jin ; Chang, Yuan ; Moore, Patrick S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (19), p.5875-5882
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Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability
Author / Creator:Lee, Donna M. ; Sun, Angela ; Patil, Sneha S. ; Liu, Lijun ; Rao, Aparna V. ; Trent, Parker T. ; Ali, Areej A. ; Liu, Catherine ; Rausch, Jessica L. ; Presutti, Laura D. ; Kaczorowski, Adam ; Schneider, Felix ; Amankulor, Nduka M. ; Shuda, Masahiro ; Duensing, Anette
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-05, Vol.12 (1), p.8275-10, Article 8275
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Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model
Author / Creator:Shuda, Masahiro ; Guastafierro, Anna ; Geng, Xuehui ; Shuda, Yoko ; Ostrowski, Stephen M. ; Lukianov, Stefan ; Jenkins, Frank J. ; Honda, Kord ; Maricich, Stephen M. ; Moore, Patrick S. ; Chang, Yuan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-11, Vol.10 (11), p.e0142329
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Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice
Author / Creator:Cao, Simon ; Jurczak, Michael J. ; Shuda, Yoko ; Sun, Rui ; Shuda, Masahiro ; Chang, Yuan ; Moore, Patrick S.
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLOS ONE, 2023-03, Vol.18 (3), p.e0282914
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Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice
Author / Creator:Sun, Rui ; Guo, Siying ; Shuda, Yoko ; Chakka, Anish B. ; Rigatti, Lora H. ; Zhao, Guangyi ; Ali, Mohammed A. E. ; Park, Christopher Y. ; Chandran, Uma ; Yu, Jian ; Bakkenist, Christopher J. ; Shuda, Masahiro ; Moore, Patrick S. ; Chang, Yuan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2023-05, Vol.18 (5), p.e0282722
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Replication Kinetics for a Reporter Merkel Cell Polyomavirus
Author / Creator:Abere, Bizunesh ; Zhou, Hongzhao ; Shuda, Masahiro ; Stolz, Donna B. ; Rapchak, Kyle ; Moore, Patrick S. ; Chang, Yuan
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2022-02, Vol.14 (3), p.473
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Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator
Author / Creator:Shuda, Masahiro ; Kwun, Hyun Jin ; Feng, Huichen ; Chang, Yuan ; Moore, Patrick S.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-09, Vol.121 (9), p.3623-3634
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Primary Sequence-Intrinsic Immune Evasion by Viral Proteins Guides CTL-Based Vaccine Strategies
Author / Creator:Wan, Li ; Shuda, Masahiro ; Chang, Yuan ; Moore, Patrick S.
Journal title:Viruses, 2025-07, Vol.17 (8), p.1035
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Merkel Cell Polyomavirus–Positive Merkel Cell Carcinoma Requires Viral Small T-Antigen for Cell Proliferation
Author / Creator:Shuda, Masahiro ; Chang, Yuan ; Moore, Patrick S.
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-05, Vol.134 (5), p.1479-1481
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Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition
Author / Creator:Harold, Alexis ; Amako, Yutaka ; Hachisuka, Junichi ; Bai, Yulong ; Li, Meng Yen ; Kubat, Linda ; Gravemeyer, Jan ; Franks, Jonathan ; Gibbs, Julia R. ; Park, Hyun Jung ; Ezhkova, Elena ; Becker, Jürgen C. ; Shuda, Masahiro
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (40), p.20104-20114
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Plant Ribosome Recycling Factor Homologue Is a Chloroplastic Protein and Is Bactericidal in Escherichia coli Carrying Temperature-Sensitive Ribosome Recycling Factor
Author / Creator:Rolland, Norbert ; Janosi, Laszlo ; Block, Maryse A. ; Shuda, Masahiro ; Teyssier, Emeline ; Miège, Christine ; Chéniclet, Catherine ; Carde, Jean-Pierre ; Kaji, Akira ; Joyard, Jacques
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (10), p.5464-5469
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Merkel Cell Polyomavirus Status Is Not Associated with Clinical Course of Merkel Cell Carcinoma
Author / Creator:Schrama, David ; Peitsch, Wiebke K. ; Zapatka, Marc ; Kneitz, Hermann ; Houben, Roland ; Eib, Steffi ; Haferkamp, Sebastian ; Moore, Patrick S. ; Shuda, Masahiro ; Thompson, John F. ; Trefzer, Uwe ; Pföhler, Claudia ; Scolyer, Richard A. ; Becker, Jürgen C.
Publisher:New York, NY: Elsevier Inc
Journal title:Journal of investigative dermatology, 2011-08, Vol.131 (8), p.1631-1638
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Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation
Author / Creator:Velásquez, Celestino ; Cheng, Erdong ; Shuda, Masahiro ; Lee-Oesterreich, Paula J. ; von Strandmann, Lisa Pogge ; Gritsenko, Marina A. ; Jacobs, Jon M. ; Moore, Patrick S. ; Chang, Yuan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (30), p.8466-8471
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Multicolor microRNA FISH effectively differentiates tumor types
Author / Creator:Renwick, Neil ; Cekan, Pavol ; Masry, Paul A. ; McGeary, Sean E. ; Miller, Jason B. ; Hafner, Markus ; Li, Zhen ; Mihailovic, Aleksandra ; Morozov, Pavel ; Brown, Miguel ; Gogakos, Tasos ; Mobin, Mehrpouya B. ; Snorrason, Einar L. ; Feilotter, Harriet E. ; Zhang, Xiao ; Perlis, Clifford S. ; Wu, Hong ; Suárez-Fariñas, Mayte ; Feng, Huichen ; Shuda, Masahiro ; Moore, Patrick S. ; Tron, Victor A. ; Chang, Yuan ; Tuschl, Thomas
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2694-2702
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ACTIVATION OF ANCHORAGE-INDEPENDENT GROWTH OF HT1080 HUMAN FIBROSARCOMA CELLS BY DEXAMETHASONE
Author / Creator:KONDOH, NOBUO ; SHUDA, MASAHIRO ; ARAI, MASAAKI ; OIKAWA, TSUNEYUKI ; YAMAMOTO, MIKIO
Publisher:Germany: Society for In Vitro Biology
Journal title:In Vitro Cellular & Developmental Biology - Animal, 2002-02, Vol.38 (2), p.111-117
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A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1
Author / Creator:Wang, Jingnan ; Li, Jianfeng ; Santana-Santos, Lucas ; Shuda, Masahiro ; Sobol, Robert W. ; Van Houten, Bennett ; Qian, Wei
Publisher:United States: Elsevier B.V
Journal title:Molecular oncology, 2015-02, Vol.9 (2), p.488-502
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Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens
Author / Creator:Wan, Li ; Xie, Bingxian ; Shuda, Masahiro ; Delgoffe, Greg ; Chang, Yuan ; Moore, Patrick S
Publisher:United States: Cold Spring Harbor Laboratory
Journal title:bioRxiv, 2024-10
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Showing 1 to 20 of 24 results

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Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

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Merkel cell polyomavirus small T antigen is a viral transcription activator that is essential for viral genome maintenance

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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

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CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation

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Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability

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Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model

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Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice

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Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

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Replication Kinetics for a Reporter Merkel Cell Polyomavirus

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Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

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Primary Sequence-Intrinsic Immune Evasion by Viral Proteins Guides CTL-Based Vaccine Strategies

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Merkel Cell Polyomavirus–Positive Merkel Cell Carcinoma Requires Viral Small T-Antigen for Cell Proliferation

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Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition

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Plant Ribosome Recycling Factor Homologue Is a Chloroplastic Protein and Is Bactericidal in Escherichia coli Carrying Temperature-Sensitive Ribosome Recycling Factor

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Merkel Cell Polyomavirus Status Is Not Associated with Clinical Course of Merkel Cell Carcinoma

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Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation

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Multicolor microRNA FISH effectively differentiates tumor types

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ACTIVATION OF ANCHORAGE-INDEPENDENT GROWTH OF HT1080 HUMAN FIBROSARCOMA CELLS BY DEXAMETHASONE

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A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1

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Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens

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