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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0806526105

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

About this item

Full title

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16272-16277

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Merkel cell polyomavirus (MCV) is a virus discovered in our laboratory at the University of Pittsburgh that is monoclonally integrated into the genome of [almost equal to]80% of human Merkel cell carcinomas (MCCs). Transcript mapping was performed to show that MCV expresses transcripts in MCCs similar to large T (LT), small T (ST), and 17kT transcr...

Alternative Titles

Full title

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0806526105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0806526105

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0806526105

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