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Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phas...
Author / Creator:Blauvelt, Andrew, Dr ; de Bruin-Weller, Marjolein, MD ; Gooderham, Melinda, MD ; Cather, Jennifer C, MD ; Weisman, Jamie, MD ; Pariser, David, Prof ; Simpson, Eric L, Prof ; Papp, Kim A, MD ; Hong, H Chih-Ho, MD ; Rubel, Diana, MD ; Foley, Peter, MD ; Prens, Errol, Prof ; Griffiths, Christopher E M, Prof ; Etoh, Takafumi, MD ; Pinto, Pedro Herranz, MD ; Pujol, Ramon M, MD ; Szepietowski, Jacek C, Prof ; Ettler, Karel, MD ; Kemény, Lajos, Prof ; Zhu, Xiaoping, PhD ; Akinlade, Bolanle, MD ; Hultsch, Thomas, MD ; Mastey, Vera, MS ; Gadkari, Abhijit, PhD ; Eckert, Laurent, PhD ; Amin, Nikhil, MD ; Graham, Neil M H, MD ; Pirozzi, Gianluca, MD ; Stahl, Neil, PhD ; Yancopoulos, George D, MD ; Shumel, Brad, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-06, Vol.389 (10086), p.2287-2303
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Disease Burden and Unmet Need in Eosinophilic Esophagitis
Author / Creator:Bredenoord, Albert J. ; Patel, Kiran ; Schoepfer, Alain M. ; Dellon, Evan S. ; Chehade, Mirna ; Aceves, Seema S. ; Spergel, Jonathan M. ; Shumel, Brad ; Deniz, Yamo ; Rowe, Paul J. ; Jacob-Nara, Juby A.
Publisher:United States: Wolters Kluwer
Journal title:The American journal of gastroenterology, 2022-08, Vol.117 (8), p.1231-1241
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Letter to the Editor Regarding ‘Matching-Adjusted Indirect Comparison of the Long-Term Efficacy Maintenance and Adverse Event Rates of Lebrikizumab Versus Dupilumab in Moderate-to-Severe Atopic Dermat...
Author / Creator:Bastian, Mike ; Freemantle, Nick ; Rossi, Ana B. ; Shumel, Brad ; Le Bagousse, Gaelle Bego ; Wang, Zhixiao ; Xu, Yingxin ; Guyot, Patricia
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2024-03, Vol.14 (3), p.819-821
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Long-Term Effectiveness of Dupilumab in Patients with Atopic Dermatitis: Results up to 3 Years from the RELIEVE-AD Study
Author / Creator:Kimball, Alexa B. ; Delevry, Dimittri ; Yang, Min ; Chuang, Chien-Chia ; Wang, Zhixiao ; Bégo-Le-Bagousse, Gaëlle ; Martins, Bruno ; Wu, Eric ; Shumel, Brad ; Wang, Jessie ; Sierka, Debra ; Chao, Jingdong ; Strober, Bruce
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2023-09, Vol.13 (9), p.2107-2120
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Patient-Reported Ocular Disorders and Symptoms in Adults with Moderate-to-Severe Atopic Dermatitis: Screening and Baseline Survey Data from a Clinical Trial
Author / Creator:Weyne, Jonathan ; Blauvelt, Andrew ; de Bruin-Weller, Marjolein ; Prens, Errol ; Asbell, Penny ; Sierka, Debra ; Chen, Zhen ; Shumel, Brad
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2020-12, Vol.10 (6), p.1415-1421
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Efficacy of dupilumab in moderate and severe atopic dermatitis
Author / Creator:Weidinger, Stephan ; Simpson, Eric L. ; Silverberg, Jonathan I. ; Schmitt, Jochen ; Leshem, Yael A. ; Katoh, Norito ; Chen, Zhen ; Zhang, Haixin ; Shumel, Brad ; Bansal, Ashish ; Chao, Jingdong ; Lu, Yufang ; Rossi, Ana B. ; Abramova, Alvina
Publisher:Madrid: John Wiley & Sons, Inc
Journal title:JEADV clinical practice, 2023-06, Vol.2 (2), p.247-260
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Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis
Author / Creator:Dellon, Evan S. ; Rothenberg, Marc E. ; Collins, Margaret H. ; Hirano, Ikuo ; Chehade, Mirna ; Bredenoord, Albert J. ; Lucendo, Alfredo J. ; Spergel, Jonathan M. ; Aceves, Seema ; Sun, Xian ; Kosloski, Matthew P. ; Kamal, Mohamed A. ; Hamilton, Jennifer D. ; Beazley, Bethany ; McCann, Eilish ; Patel, Kiran ; Mannent, Leda P. ; Laws, Elizabeth ; Akinlade, Bolanle ; Amin, Nikhil ; Lim, Wei Keat ; Wipperman, Matthew F. ; Ruddy, Marcella ; Patel, Naimish ; Weinreich, David R. ; Yancopoulos, George D. ; Shumel, Brad ; Maloney, Jennifer ; Giannelou, Angeliki ; Shabbir, Arsalan
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-12, Vol.387 (25), p.2317-2330
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ArticlesPeer ReviewedFull Text
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
Author / Creator:Dewey, Frederick E ; Gusarova, Viktoria ; Dunbar, Richard L ; O’Dushlaine, Colm ; Schurmann, Claudia ; Gottesman, Omri ; McCarthy, Shane ; Van Hout, Cristopher V ; Bruse, Shannon ; Dansky, Hayes M ; Leader, Joseph B ; Murray, Michael F ; Ritchie, Marylyn D ; Kirchner, H. Lester ; Habegger, Lukas ; Lopez, Alex ; Penn, John ; Zhao, An ; Shao, Weiping ; Stahl, Neil ; Murphy, Andrew J ; Hamon, Sara ; Bouzelmat, Aurelie ; Zhang, Rick ; Shumel, Brad ; Pordy, Robert ; Gipe, Daniel ; Herman, Gary A ; Sheu, Wayne H.H ; Lee, I-Te ; Liang, Kae-Woei ; Guo, Xiuqing ; Rotter, Jerome I ; Chen, Yii-Der I ; Kraus, William E ; Shah, Svati H ; Damrauer, Scott ; Small, Aeron ; Rader, Daniel J ; Wulff, Anders Berg ; Nordestgaard, Børge G ; Tybjærg-Hansen, Anne ; van den Hoek, Anita M ; Princen, Hans M.G ; Ledbetter, David H ; Carey, David J ; Overton, John D ; Reid, Jeffrey G ; Sasiela, William J ; Banerjee, Poulabi ; Shuldiner, Alan R ; Borecki, Ingrid B ; Teslovich, Tanya M ; Yancopoulos, George D ; Mellis, Scott J ; Gromada, Jesper ; Baras, Aris
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-07, Vol.377 (3), p.211-221
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ArticlesPeer ReviewedFull Text
Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis
Author / Creator:Beck, Lisa A. ; Thaçi, Diamant ; Deleuran, Mette ; Blauvelt, Andrew ; Bissonnette, Robert ; de Bruin-Weller, Marjolein ; Hide, Michihiro ; Sher, Lawrence ; Hussain, Iftikhar ; Chen, Zhen ; Khokhar, Faisal A. ; Beazley, Bethany ; Ruddy, Marcella ; Patel, Naimish ; Graham, Neil M. H. ; Ardeleanu, Marius ; Shumel, Brad
Publisher:Cham: Springer International Publishing
Journal title:American journal of clinical dermatology, 2020-08, Vol.21 (4), p.567-577
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Integrated Exposure–Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis
Author / Creator:Briggs, Emily ; Kamal, Mohamed A. ; Kosloski, Matthew P. ; Linsmeier, Ian ; Jusko, Natalie ; Dolphin, Nancy ; Chittenden, Jason ; Simpson, Eric L. ; Paller, Amy S. ; Siegfried, Elaine C. ; Shumel, Brad ; Levit, Noah A. ; Bansal, Ashish ; Davis, John D. ; Chapel, Sunny ; Smith, David E. ; Huniti, Nidal
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2023-11, Vol.40 (11), p.2653-2666
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ArticlesPeer ReviewedFull Text
Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma
Author / Creator:Bansal, Ashish ; Simpson, Eric L. ; Paller, Amy S. ; Siegfried, Elaine C. ; Blauvelt, Andrew ; de Bruin-Weller, Marjolein ; Corren, Jonathan ; Sher, Lawrence ; Guttman-Yassky, Emma ; Chen, Zhen ; Daizadeh, Nadia ; Kamal, Mohamed A. ; Shumel, Brad ; Mina-Osorio, Paola ; Mannent, Leda ; Patel, Naimish ; Graham, Neil M. H. ; Khokhar, Faisal A. ; Ardeleanu, Marius
Publisher:Cham: Springer International Publishing
Journal title:American journal of clinical dermatology, 2021-01, Vol.22 (1), p.101-115
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ArticlesPeer ReviewedFull Text
Disease burden and unmet need in eosinophilic esophagitis
Author / Creator:Bredenoord, Albert J. ; Patel, Kiran ; Schoepfer, Alain M. ; Dellon, Evan S. ; Chehade, Mirna ; Aceves, Seema S. ; Spergel, Jonathan M. ; Shumel, Brad ; Deniz, Yamo ; Rowe, Paul J. ; Jacob-Nara, Juby A.
Publisher:Wolters Kluwer
Journal title:The American journal of gastroenterology, 2022-04
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Dupilumab with Topical Corticosteroids Provides Rapid and Sustained Improvement in Adults with Moderate-to-Severe Atopic Dermatitis Across Anatomic Regions Over 52 Weeks
Author / Creator:Blauvelt, Andrew ; de Bruin-Weller, Marjolein ; Simpson, Eric L. ; Chen, Zhen ; Zhang, Annie ; Shumel, Brad
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2022-01, Vol.12 (1), p.223-231
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Laboratory Safety of Dupilumab in Patients Aged 6–11 Years with Severe Atopic Dermatitis: Results from a Phase III Clinical Trial
Author / Creator:Paller, Amy S. ; Wollenberg, Andreas ; Siegfried, Elaine ; Thaçi, Diamant ; Cork, Michael J. ; Arkwright, Peter D. ; Gooderham, Melinda ; Sun, Xian ; O’Malley, John T. ; Khokhar, Faisal A. ; Vakil, Jignesh ; Bansal, Ashish ; Rosner, Karli ; Shumel, Brad ; Levit, Noah A.
Publisher:Cham: Springer International Publishing
Journal title:Paediatric drugs, 2021-09, Vol.23 (5), p.515-527
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Dupilumab Maintains Long-Term Disease Control in Adults with Moderate-to-Severe Atopic Dermatitis as Measured by Well-Controlled Weeks: Results From the LIBERTY AD CHRONOS Clinical Trial
Author / Creator:Wu, Jashin J. ; Spelman, Lynda ; Tan, Jerry L. ; Etoh, Takafumi ; Zhang, Haixin ; Shumel, Brad ; Rossi, Ana B.
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2021-04, Vol.11 (2), p.327-330
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Dupilumab Demonstrates Rapid and Consistent Improvement in Extent and Signs of Atopic Dermatitis Across All Anatomical Regions in Pediatric Patients 6 Years of Age and Older
Author / Creator:Simpson, Eric L. ; Paller, Amy S. ; Siegfried, Elaine C. ; Thaçi, Diamant ; Wollenberg, Andreas ; Cork, Michael J. ; Marcoux, Danielle ; Huang, Rui ; Chen, Zhen ; Rossi, Ana B. ; Shumel, Brad ; Sierka, Debra ; Bansal, Ashish
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2021-10, Vol.11 (5), p.1643-1656
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Continued Treatment with Dupilumab is Associated with Improved Efficacy in Adults with Moderate-to-Severe Atopic Dermatitis Not Achieving Optimal Responses with Short-Term Treatment
Author / Creator:Armstrong, April ; Blauvelt, Andrew ; Simpson, Eric L. ; Smith, Catherine H. ; Herranz, Pedro ; Kataoka, Yoko ; Seo, Seong Jun ; Ferrucci, Silvia M. ; Chao, Jingdong ; Chen, Zhen ; Rossi, Ana B. ; Shumel, Brad ; Tomondy, Paul
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2022-01, Vol.12 (1), p.195-202
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Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis
Author / Creator:Yosipovitch, Gil ; de Bruin-Weller, Marjolein ; Armstrong, April ; Wu, Jashin J. ; Herranz, Pedro ; Thaçi, Diamant ; Delevry, Dimittri ; Bagousse, Gaëlle Bégo-Le ; Zhang, Raymond ; Shumel, Brad ; Rossi, Ana B. ; Chao, Jingdong
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2021-12, Vol.11 (6), p.2147-2157
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ReportsFull Text
Dupilumab with Topical Corticosteroids Provides Rapid and Sustained Improvement in Adults with Moderate-to-Severe Atopic Dermatitis Across Anatomic Regions Over 52 Weeks
Author / Creator:Blauvelt, Andrew ; de Bruin-Weller, Marjolein ; Simpson, Eric L ; Chen, Zhen ; Zhang, Annie ; Shumel, Brad
Publisher:Springer
Journal title:Dermatology and Therapy, 2022, Vol.12 (1), p.223
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ReportsFull Text
Long-Term Effectiveness of Dupilumab in Patients with Atopic Dermatitis: Results up to 3 Years from the RELIEVE-AD Study
Author / Creator:Kimball, Alexa B ; Delevry, Dimittri ; Yang, Min ; Chuang, Chien-Chia ; Wang, Zhixiao ; Bégo-Le-Bagousse, Gaëlle ; Martins, Bruno ; Wu, Eric ; Shumel, Brad ; Wang, Jessie ; Sierka, Debra ; Chao, Jingdong ; Strober, Bruce
Publisher:Springer
Journal title:Dermatology and Therapy, 2023, Vol.13 (9), p.2107
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Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phas...

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Disease Burden and Unmet Need in Eosinophilic Esophagitis

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Letter to the Editor Regarding ‘Matching-Adjusted Indirect Comparison of the Long-Term Efficacy Maintenance and Adverse Event Rates of Lebrikizumab Versus Dupilumab in Moderate-to-Severe Atopic Dermat...

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Long-Term Effectiveness of Dupilumab in Patients with Atopic Dermatitis: Results up to 3 Years from the RELIEVE-AD Study

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Patient-Reported Ocular Disorders and Symptoms in Adults with Moderate-to-Severe Atopic Dermatitis: Screening and Baseline Survey Data from a Clinical Trial

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Efficacy of dupilumab in moderate and severe atopic dermatitis

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Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis

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Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

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Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis

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Integrated Exposure–Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis

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Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma

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Disease burden and unmet need in eosinophilic esophagitis

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Dupilumab with Topical Corticosteroids Provides Rapid and Sustained Improvement in Adults with Moderate-to-Severe Atopic Dermatitis Across Anatomic Regions Over 52 Weeks

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Laboratory Safety of Dupilumab in Patients Aged 6–11 Years with Severe Atopic Dermatitis: Results from a Phase III Clinical Trial

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Dupilumab Maintains Long-Term Disease Control in Adults with Moderate-to-Severe Atopic Dermatitis as Measured by Well-Controlled Weeks: Results From the LIBERTY AD CHRONOS Clinical Trial

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Dupilumab Demonstrates Rapid and Consistent Improvement in Extent and Signs of Atopic Dermatitis Across All Anatomical Regions in Pediatric Patients 6 Years of Age and Older

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Continued Treatment with Dupilumab is Associated with Improved Efficacy in Adults with Moderate-to-Severe Atopic Dermatitis Not Achieving Optimal Responses with Short-Term Treatment

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Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis

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Dupilumab with Topical Corticosteroids Provides Rapid and Sustained Improvement in Adults with Moderate-to-Severe Atopic Dermatitis Across Anatomic Regions Over 52 Weeks

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Long-Term Effectiveness of Dupilumab in Patients with Atopic Dermatitis: Results up to 3 Years from the RELIEVE-AD Study

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