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21 results for Singhania,+Akul

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ArticlesPeer ReviewedFull Text
The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis
Author / Creator:Singhania, Akul ; Wilkinson, Robert J. ; Rodrigue, Marc ; Haldar, Pranabashis ; O’Garra, Anne
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-11, Vol.19 (11), p.1159-1168
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Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis
Author / Creator:Moreira-Teixeira, Lúcia ; Tabone, Olivier ; Graham, Christine M. ; Singhania, Akul ; Stavropoulos, Evangelos ; Redford, Paul S. ; Chakravarty, Probir ; Priestnall, Simon L. ; Suarez-Bonnet, Alejandro ; Herbert, Eleanor ; Mayer-Barber, Katrin D. ; Sher, Alan ; Fonseca, Kaori L. ; Sousa, Jeremy ; Cá, Baltazar ; Verma, Raman ; Haldar, Pranabashis ; Saraiva, Margarida ; O’Garra, Anne
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-04, Vol.21 (4), p.464-476
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A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC
Author / Creator:Bennett, Jason ; Pomaznoy, Mikhail ; Singhania, Akul ; Peters, Bjoern
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2021-10, Vol.17 (10), p.e1009459-e1009459
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A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection
Author / Creator:Singhania, Akul ; Verma, Raman ; Graham, Christine M. ; Lee, Jo ; Tran, Trang ; Richardson, Matthew ; Lecine, Patrick ; Leissner, Philippe ; Berry, Matthew P. R. ; Wilkinson, Robert J. ; Kaiser, Karine ; Rodrigue, Marc ; Woltmann, Gerrit ; Haldar, Pranabashis ; O’Garra, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-06, Vol.9 (1), p.2308-17, Article 2308
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The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse
Author / Creator:Singhania, Akul ; Pham, John ; Dhanwani, Rekha ; Frazier, April ; Rezende Dutra, Juliana ; Marder, Karen S. ; Phillips, Elizabeth ; Mallal, Simon ; Amara, Amy W. ; Standaert, David G. ; Sulzer, David ; Peters, Bjoern ; Sette, Alessandro ; Lindestam Arlehamn, Cecilia S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.302-302, Article 302
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An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients
Author / Creator:Spina, Celsa A. ; Anderson, Jenny ; Archin, Nancie M. ; Bosque, Alberto ; Chan, Jonathan ; Famiglietti, Marylinda ; Greene, Warner C. ; Kashuba, Angela ; Lewin, Sharon R. ; Margolis, David M. ; Mau, Matthew ; Ruelas, Debbie ; Saleh, Suha ; Shirakawa, Kotaro ; Siliciano, Robert F. ; Singhania, Akul ; Soto, Paula C. ; Terry, Valeri H. ; Verdin, Eric ; Woelk, Christopher ; Wooden, Stacey ; Xing, Sifei ; Planelles, Vicente
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-12, Vol.9 (12), p.e1003834-e1003834
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Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma
Author / Creator:Singhania, Akul ; Rupani, Hitasha ; Jayasekera, Nivenka ; Lumb, Simon ; Hales, Paul ; Gozzard, Neil ; Davies, Donna E. ; Woelk, Christopher H. ; Howarth, Peter H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-01, Vol.12 (1), p.e0168680-e0168680
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Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis
Author / Creator:Sathyamoorthy, Tarangini ; Sandhu, Gurjinder ; Tezera, Liku B. ; Thomas, Richard ; Singhania, Akul ; Woelk, Christopher H. ; Dimitrov, Borislav D. ; Agranoff, Dan ; Evans, Carlton A. W. ; Friedland, Jon S. ; Elkington, Paul T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-01, Vol.10 (1), p.e0117605-e0117605
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Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection
Author / Creator:Woelk, Christopher H ; Zhang, Jin X ; Walls, Lorraine ; Viriyakosol, Suganya ; Singhania, Akul ; Kirkland, Theo N ; Fierer, Joshua
Publisher:England: BioMed Central
Journal title:BMC microbiology, 2012-09, Vol.12 (1), p.218-218
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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Author / Creator:Gallo, David ; Young, Jordan T. F. ; Fourtounis, Jimmy ; Martino, Giovanni ; Álvarez-Quilón, Alejandro ; Bernier, Cynthia ; Duffy, Nicole M. ; Papp, Robert ; Roulston, Anne ; Stocco, Rino ; Szychowski, Janek ; Veloso, Artur ; Alam, Hunain ; Baruah, Prasamit S. ; Fortin, Alexanne Bonneau ; Bowlan, Julian ; Chaudhary, Natasha ; Desjardins, Jessica ; Dietrich, Evelyne ; Fournier, Sara ; Fugère-Desjardins, Chloe ; Goullet de Rugy, Theo ; Leclaire, Marie-Eve ; Liu, Bingcan ; Bhaskaran, Vivek ; Mamane, Yael ; Melo, Henrique ; Nicolas, Olivier ; Singhania, Akul ; Szilard, Rachel K. ; Tkáč, Ján ; Yin, Shou Yun ; Morris, Stephen J. ; Zinda, Michael ; Marshall, C. Gary ; Durocher, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-04, Vol.604 (7907), p.749-756
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ArticlesPeer ReviewedFull Text
Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma
Author / Creator:Singhania, Akul ; Wallington, Joshua C. ; Smith, Caroline G. ; Horowitz, Daniel ; Staples, Karl J. ; Howarth, Peter H. ; Gadola, Stephan D. ; Djukanović, Ratko ; Woelk, Christopher H. ; Hinks, Timothy S. C.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2018-02, Vol.58 (2), p.261-270
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ArticlesPeer ReviewedFull Text
Transcriptomics in TB: the immune response and diagnosis
Author / Creator:Singhania, Akul ; Wilkinson, Robert J. ; Rodrigue, Marc ; Haldar, Pranabashis ; O’Garra, Anne
Journal title:Nature immunology, 2018-10, Vol.19 (11), p.1159-1168
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ArticlesPeer ReviewedFull Text
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
Author / Creator:Singhania, Akul ; Graham, Christine M. ; Gabryšová, Leona ; Moreira-Teixeira, Lúcia ; Stavropoulos, Evangelos ; Pitt, Jonathan M. ; Chakravarty, Probir ; Warnatsch, Annika ; Branchett, William J. ; Conejero, Laura ; Lin, Jing-Wen ; Davidson, Sophia ; Wilson, Mark S. ; Bancroft, Gregory ; Langhorne, Jean ; Frickel, Eva ; Sesay, Abdul K. ; Priestnall, Simon L. ; Herbert, Eleanor ; Ioannou, Marianna ; Wang, Qian ; Humphreys, Ian R. ; Dodd, Jonathan ; Openshaw, Peter J. M. ; Mayer-Barber, Katrin D. ; Jankovic, Dragana ; Sher, Alan ; Lloyd, Clare M. ; Baldwin, Nicole ; Chaussabel, Damien ; Papayannopoulos, Venizelos ; Wack, Andreas ; Banchereau, Jacques F. ; Pascual, Virginia M. ; O’Garra, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2887-21, Article 2887
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ArticlesPeer ReviewedFull Text
IFN-γ Influences Epithelial Antiviral Responses via Histone Methylation of the RIG-I Promoter
Author / Creator:Spalluto, C. Mirella ; Singhania, Akul ; Cellura, Doriana ; Woelk, Christopher H. ; Sanchez-Elsner, Tilman ; Staples, Karl J. ; Wilkinson, Tom M. A.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2017-10, Vol.57 (4), p.428-438
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Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature
Author / Creator:Viriyakosol, Suganya ; Singhania, Akul ; Fierer, Joshua ; Goldberg, Jonathan ; Kirkland, Theo N ; Woelk, Christopher H
Publisher:England: BioMed Central Ltd
Journal title:BMC microbiology, 2013-05, Vol.13 (1), p.121-121, Article 121
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Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitisinfection
Author / Creator:Woelk, Christopher H ; Zhang, Jin X ; Walls, Lorraine ; Viriyakosol, Suganya ; Singhania, Akul ; Kirkland, Theo N ; Fierer, Joshua
Publisher:BioMed Central Ltd
Journal title:BMC microbiology, 2012-09, Vol.12 (1), Article 218
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An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients: e1003834
Author / Creator:Spina, Celsa A ; Anderson, Jenny ; Archin, Nancie M ; Bosque, Alberto ; Chan, Jonathan ; Famiglietti, Marylinda ; Greene, Warner C ; Kashuba, Angela ; Lewin, Sharon R ; Margolis, David M ; Mau, Matthew ; Ruelas, Debbie ; Saleh, Suha ; Shirakawa, Kotaro ; Siliciano, Robert F ; Singhania, Akul ; Soto, Paula C ; Terry, Valeri H ; Verdin, Eric ; Woelk, Christopher ; Wooden, Stacey ; Xing, Sifei ; Planelles, Vicente
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2013-12, Vol.9 (12)
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ArticlesPeer ReviewedFull Text
Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis: e0117605
Author / Creator:Sathyamoorthy, Tarangini ; Sandhu, Gurjinder ; Tezera, Liku B ; Thomas, Richard ; Singhania, Akul ; Woelk, Christopher H ; Dimitrov, Borislav D ; Agranoff, Dan ; Evans, Carlton AW ; Friedland, Jon S
Journal title:PloS one, 2015-01, Vol.10 (1)
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ArticlesFull Text
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
Author / Creator:Singhania, Akul ; Dubelko, Paige ; Kuan, Rebecca ; Chronister, William D ; Muskat, Kaylin ; Das, Jyotirmoy ; Phillips, Elizabeth J ; Mallal, Simon A ; Seumois, Grégory ; Pandurangan Vijayanand ; Sette, Alessandro ; Lerm, Maria ; Peters, Bjoern ; Cecilia S Lindestam Arlehamn
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-08
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Differential expression of an alternative splice variant of IL-12R 1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosis
Author / Creator:Das, Mrinal K ; Ray, Aurelie A ; Cai, Yi ; Singhania, Akul ; Graham, Christine ; Liao, Mingfeng ; Fountain, Jeffrey J ; Pearl, John E ; Pareek, Manish ; Haldar, Pranabashis ; O'garra, Anne ; Chen, Xinchun ; Cooper, Andrea M
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-02
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The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis

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Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

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A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC

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A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

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The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse

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An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

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Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma

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Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis

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Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection

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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

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Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma

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Transcriptomics in TB: the immune response and diagnosis

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Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

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IFN-γ Influences Epithelial Antiviral Responses via Histone Methylation of the RIG-I Promoter

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Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature

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Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitisinfection

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An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients: e1003834

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Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis: e0117605

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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

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Differential expression of an alternative splice variant of IL-12R 1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosis

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