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ArticlesPeer ReviewedFull Text
NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Author / Creator:Hou, Yujun ; Lautrup, Sofie ; Cordonnier, Stephanie ; Wang, Yue ; Croteau, Deborah L. ; Zavala, Eduardo ; Zhang, Yongqing ; Moritoh, Kanako ; O’Connell, Jennifer F. ; Baptiste, Beverly A. ; Stevnsner, Tinna V. ; Mattson, Mark P. ; Bohr, Vilhelm A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.E1876-E1885
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Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease
Author / Creator:Ansari, Aneesa ; Rahman, Md. Shahedur ; Saha, Subbroto K. ; Saikot, Forhad K. ; Deep, Akash ; Kim, Ki‐Hyun
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2017-02, Vol.16 (1), p.4-16
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Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target
Author / Creator:Zhang, Jin ; Xiang, Honggang ; Liu, Jie ; Chen, Yi ; He, Rong-Rong ; Liu, Bo
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (18), p.8315-8342
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The role of SIRT3-mediated mitochondrial homeostasis in osteoarthritis
Author / Creator:He, Yuzhe ; Wu, Zhipeng ; Xu, Langhai ; Xu, Kai ; Chen, Zhonggai ; Ran, Jisheng ; Wu, Lidong
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2020-10, Vol.77 (19), p.3729-3743
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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity
Author / Creator:Zhang, Tian ; Liu, Jingxin ; Shen, Shengnan ; Tong, Qiang ; Ma, Xiaojun ; Lin, Ligen
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-01, Vol.27 (1), p.329-344
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Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury
Author / Creator:Morigi, Marina ; Perico, Luca ; Rota, Cinzia ; Longaretti, Lorena ; Conti, Sara ; Rottoli, Daniela ; Novelli, Rubina ; Remuzzi, Giuseppe ; Benigni, Ariela
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-02, Vol.125 (2), p.715-726
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Circadian Clock NAD⁺ Cycle Drives Mitochondrial Oxidative Metabolism in Mice
Author / Creator:Peek, Clara Bien ; Affinati, Alison H. ; Ramsey, Kathryn Moynihan ; Kuo, Hsin-Yu ; Yu, Wei ; Sena, Laura A. ; Ilkayeva, Olga ; Marcheva, Biliana ; Kobayashi, Yumiko ; Omura, Chiaki ; Levine, Daniel C. ; Bacsik, David J. ; Gius, David ; Newgard, Christopher B. ; Goetzman, Eric ; Chandel, Navdeep S. ; Denu, John M. ; Mrksich, Milan ; Bass, Joseph
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6158), p.591-591
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Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
Author / Creator:Chen, Yaohui ; Zhang, Jinye ; Lin, Yan ; Lei, Qunying ; Guan, Kun‐Liang ; Zhao, Shimin ; Xiong, Yue
Publisher:London: Nature Publishing Group UK
Journal title:EMBO reports, 2011-06, Vol.12 (6), p.534-541
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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
Author / Creator:Rardin, Matthew J. ; Newman, John C. ; Held, Jason M. ; Cusack, Michael P. ; Sorensen, Dylan J. ; Li, Biao ; Schilling, Birgit ; Mooney, Sean D. ; Kahn, C. Ronald ; Verdin, Eric ; Gibson, Bradford W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (16), p.6601-6606
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SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice
Author / Creator:Liu, Yong ; Cheng, Aiwu ; Li, Yu-Jiao ; Yang, Ying ; Kishimoto, Yuki ; Zhang, Shi ; Wang, Yue ; Wan, Ruiqian ; Raefsky, Sophia M. ; Lu, Daoyuan ; Saito, Takashi ; Saido, Takaomi ; Zhu, Jian ; Wu, Long-Jun ; Mattson, Mark P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1886-1886, Article 1886
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The updated biology of hypoxia-inducible factor
Author / Creator:Greer, Samantha N ; Metcalf, Julie L ; Wang, Yi ; Ohh, Michael
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2012-05, Vol.31 (11), p.2448-2460
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Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis
Author / Creator:Wei, Zhen ; Song, Jinglue ; Wang, Guanghui ; Cui, Ximao ; Zheng, Jun ; Tang, Yunlan ; Chen, Xinyuan ; Li, Jixi ; Cui, Long ; Liu, Chen-Ying ; Yu, Wei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4468-16, Article 4468
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Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway
Author / Creator:Park, Jae-Hyeon ; Burgess, Jeremy D ; Faroqi, Ayman H ; DeMeo, Natasha N ; Fiesel, Fabienne C ; Springer, Wolfdieter ; Delenclos, Marion ; McLean, Pamela J
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2020-01, Vol.15 (1), p.5-5, Article 5
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Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3
Author / Creator:Reiter, Russel J ; Tan, Dun Xian ; Rosales-Corral, Sergio ; Galano, Annia ; Jou, Mei-Jie ; Acuna-Castroviejo, Dario
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-08, Vol.19 (8), p.2439
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SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo
Author / Creator:Yi, Xiuli ; Guo, Weinan ; Shi, Qiong ; Yang, Yuqi ; Zhang, Weigang ; Chen, Xuguang ; Kang, Pan ; Chen, Jiaxi ; Cui, Tingting ; Ma, Jinyuan ; Wang, Huina ; Guo, Sen ; Chang, Yuqian ; Liu, Ling ; Jian, Zhe ; Wang, Lin ; Xiao, Qian ; Li, Shuli ; Gao, Tianwen ; Li, Chunying
Publisher:Australia: Ivyspring International Publisher
Journal title:Theranostics, 2019-01, Vol.9 (6), p.1614-1633
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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
Author / Creator:Pillai, Vinodkumar B. ; Samant, Sadhana ; Sundaresan, Nagalingam R. ; Raghuraman, Hariharasundaram ; Kim, Gene ; Bonner, Michael Y. ; Arbiser, Jack L. ; Walker, Douglas I. ; Jones, Dean P. ; Gius, David ; Gupta, Mahesh P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-04, Vol.6 (1), p.6656-6656, Article 6656
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ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation
Author / Creator:Hor, Jin-Hui ; Santosa, Munirah Mohamad ; Lim, Valerie Jing Wen ; Ho, Beatrice Xuan ; Taylor, Amy ; Khong, Zi Jian ; Ravits, John ; Fan, Yong ; Liou, Yih-Cherng ; Soh, Boon-Seng ; Ng, Shi-Yan
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-04, Vol.28 (4), p.1379-1397
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SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism
Author / Creator:Liu, Ling-Xin ; Zheng, Xue-Hui ; Hai, Jing-Han ; Zhang, Chun-Mei ; Ti, Yun ; Chen, Tong-Shuai ; Bu, Pei-Li
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-04, Vol.19 (4), p.e0301990-e0301990
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Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics
Author / Creator:Zhang, Andi ; Pan, Yi ; Wang, Hao ; Ding, Rui ; Zou, Tianyuan ; Guo, Dongye ; Shen, Yilin ; Ji, Peilin ; Huang, Weiyi ; Wen, Qing ; Wang, Quan ; Hu, Haixia ; Wu, Jichang ; Xiang, Mingliang ; Ye, Bin
Publisher:England: John Wiley and Sons Inc
Journal title:Aging cell, 2024-04, Vol.23 (4), p.e14091
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A molecular mechanism for direct sirtuin activation by resveratrol
Author / Creator:Gertz, Melanie ; Nguyen, Giang Thi Tuyet ; Fischer, Frank ; Suenkel, Benjamin ; Schlicker, Christine ; Fränzel, Benjamin ; Tomaschewski, Jana ; Aladini, Firouzeh ; Becker, Christian ; Wolters, Dirk ; Steegborn, Clemens
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e49761-e49761
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NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

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Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease

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Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target

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The role of SIRT3-mediated mitochondrial homeostasis in osteoarthritis

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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity

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Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury

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Circadian Clock NAD⁺ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

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Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

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SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice

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The updated biology of hypoxia-inducible factor

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Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis

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Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

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Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

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SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo

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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

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ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation

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SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism

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Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics

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A molecular mechanism for direct sirtuin activation by resveratrol

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