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ArticlesPeer ReviewedFull Text
Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis
Author / Creator:Canman, Julie C ; Lewellyn, Lindsay ; Laband, Kimberley ; Smerdon, Stephen J ; Desai, Arshad ; Bowerman, Bruce ; Oegema, Karen
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5907), p.1543-1546
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Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes
Author / Creator:Rock, Jeremy M. ; Lim, Daniel ; Stach, Lasse ; Ogrodowicz, Roksana W. ; Keck, Jamie M. ; Jones, Michele H. ; Wong, Catherine C. L. ; Yates, John R. ; Winey, Mark ; Smerdon, Stephen J. ; Yaffe, Michael B. ; Amon, Angelika
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6134), p.871-875
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ArticlesPeer ReviewedFull Text
Uncoupling conformational states from activity in an allosteric enzyme
Author / Creator:Pisco, João P. ; de Chiara, Cesira ; Pacholarz, Kamila J. ; Garza-Garcia, Acely ; Ogrodowicz, Roksana W. ; Walker, Philip A. ; Barran, Perdita E. ; Smerdon, Stephen J. ; de Carvalho, Luiz Pedro S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-08, Vol.8 (1), p.203-10, Article 203
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ArticlesPeer ReviewedFull Text
KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity
Author / Creator:Fournier, Marjorie ; Rodrigue, Amélie ; Milano, Larissa ; Bleuyard, Jean-Yves ; Couturier, Anthony M ; Wall, Jacob ; Ellins, Jessica ; Hester, Svenja ; Smerdon, Stephen J ; Tora, László ; Masson, Jean-Yves ; Esashi, Fumiko
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2022-10, Vol.11
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IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases
Author / Creator:Ben-Addi, Abduelhakem ; Mambole-Dema, Agnes ; Brender, Christine ; Martin, Stephen R. ; Janzen, Julia ; Kjaer, Sven ; Smerdon, Stephen J. ; Ley, Steven C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (23), p.E2394-E2403
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ArticlesPeer ReviewedFull Text
High-resolution structure of a retroviral capsid hexameric amino-terminal domain
Author / Creator:Mortuza, Gulnahar B. ; Haire, Lesley F. ; Stevens, Anthony ; Smerdon, Stephen J. ; Stoye, Jonathan P. ; Taylor, Ian A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2004-09, Vol.431 (7007), p.481-485
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RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
Author / Creator:Abu-Libdeh, Bassam ; Jhujh, Satpal S. ; Dhar, Srijita ; Sommers, Joshua A. ; Datta, Arindam ; Longo, Gabriel M.C. ; Grange, Laura J. ; Reynolds, John J. ; Cooke, Sophie L. ; McNee, Gavin S. ; Hollingworth, Robert ; Woodward, Beth L. ; Ganesh, Anil N. ; Smerdon, Stephen J. ; Nicolae, Claudia M. ; Durlacher-Betzer, Karina ; Molho-Pessach, Vered ; Abu-Libdeh, Abdulsalam ; Meiner, Vardiella ; Moldovan, George-Lucian ; Roukos, Vassilis ; Harel, Tamar ; Brosh, Robert M. ; Stewart, Grant S.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-03, Vol.132 (5), p.1-17
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The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage
Author / Creator:Larsen, Dorthe H. ; Hari, Flurina ; Clapperton, Julie A. ; Gwerder, Myriam ; Gutsche, Katrin ; Altmeyer, Matthias ; Jungmichel, Stephanie ; Toledo, Luis I. ; Fink, Daniel ; Rask, Maj-Britt ; Grøfte, Merete ; Lukas, Claudia ; Nielsen, Michael L. ; Smerdon, Stephen J. ; Lukas, Jiri ; Stucki, Manuel
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2014-08, Vol.16 (8), p.792-803
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A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint
Author / Creator:van Vugt, Marcel A. T. M. ; Gardino, Alexandra K. ; Linding, Rune ; Ostheimer, Gerard J. ; Reinhardt, H. Christian ; Ong, Shao-En ; Tan, Chris S. ; Miao, Hua ; Keezer, Susan M. ; Li, Jeijin ; Pawson, Tony ; Lewis, Timothy A. ; Carr, Steven A. ; Smerdon, Stephen J. ; Brummelkamp, Thijn R. ; Yaffe, Michael B.
Publisher:San Francisco, USA: Public Library of Science
Journal title:PLoS biology, 2010-01, Vol.8 (1), p.e1000287
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ArticlesPeer ReviewedFull Text
Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans
Author / Creator:Fletcher, Sally C. ; Hall, Charlotte ; Kennedy, Tristan J. ; Pajusalu, Sander ; Wojcik, Monica H. ; Boora, Uncaar ; Li, Chan ; Oja, Kaisa Teele ; Hendrix, Eline ; Westrip, Christian A.E. ; Andrijes, Regina ; Piasecka, Sonia K. ; Singh, Mansi ; El-Asrag, Mohammed E. ; Ptasinska, Anetta ; Tillmann, Vallo ; Higgs, Martin R. ; Carere, Deanna A. ; Beggs, Andrew D. ; Pappas, John ; Rabin, Rachel ; Smerdon, Stephen J. ; Stewart, Grant S. ; Õunap, Katrin ; Coleman, Mathew L.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-04, Vol.133 (7), p.1-14
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The structure of the GTPase-activating domain from p50rhoGAP
Author / Creator:Barrett, Tracey ; Xiao, Bing ; Dodson, Eleanor J. ; Dodson, Guy ; Ludbrook, Steven B. ; Nurmahomed, Kurshid ; Gamblin, Steven J. ; Musacchio, Andrea ; Smerdon, Stephen J. ; Eccleston, John F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1997-01, Vol.385 (6615), p.458-461
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Key features of the interaction between Pcf11 CID and RNA polymerase II CTD
Author / Creator:Noble, Christian G ; Hollingworth, David ; Martin, Stephen R ; Ennis-Adeniran, Valerie ; Smerdon, Stephen J ; Kelly, Geoff ; Taylor, Ian A ; Ramos, Andres
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2005-02, Vol.12 (2), p.144-151
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Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
Author / Creator:Xiao, Bing ; Smerdon, Stephen J. ; Jones, David H. ; Dodson, Guy G. ; Soneji, Yasmina ; Aitken, Alastair ; Gamblin, Steven J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1995-07, Vol.376 (6536), p.188-191
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A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint
Author / Creator:van Vugt, Marcel A T M ; Gardino, Alexandra K ; Linding, Rune ; Ostheimer, Gerard J ; Reinhardt, H Christian ; Ong, Shao-En ; Tan, Chris S ; Miao, Hua ; Keezer, Susan M ; Li, Jeijin ; Pawson, Tony ; Lewis, Timothy A ; Carr, Steven A ; Smerdon, Stephen J ; Brummelkamp, Thijn R ; Yaffe, Michael B
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS biology, 2010-01, Vol.8 (1), p.e1000287-e1000287
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The Use of In Vitro Peptide-Library Screens in the Analysis of Phosphoserine/Threonine-Binding Domain Structure and Function
Author / Creator:Yaffe, Michael B. ; Smerdon, Stephen J.
Publisher:United States: Annual Reviews, Inc
Journal title:Annual review of biophysics and biomolecular structure, 2004-01, Vol.33 (1), p.225-244
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Erratum: High-resolution structure of a retroviral capsid hexameric amino-terminal domain
Author / Creator:Mortuza, Gulnahar B. ; Haire, Lesley F. ; Stevens, Anthony ; Smerdon, Stephen J. ; Stoye, Jonathan P. ; Taylor, Ian A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2004-10, Vol.431 (7011), p.1017-1017
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The crystal structure of NusB from Mycobacterium tuberculosis
Author / Creator:Gopal, B. ; Haire, Lesley F. ; Cox, Robert A. ; Jo Colston, M. ; Major, Sarah ; Brannigan, Jim A. ; Smerdon, Stephen J. ; Dodson, Guy
Publisher:United States: Nature Publishing Group
Journal title:Nature structural & molecular biology, 2000-06, Vol.7 (6), p.475-478
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Support for shared ancestry of GAPs
Author / Creator:Rittinger, Katrin ; Taylor, William R. ; Smerdon, Stephen J. ; Gamblin, Steven J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1998-04, Vol.392 (6675), p.448-448
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KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity
Author / Creator:Fournier, Marjorie ; Jean-Yves Bleuyard ; Couturier, Anthony M ; Ellins, Jessica ; Hester, Svenja ; Smerdon, Stephen J ; Laszlo Tora ; Esashi, Fumiko
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-01
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Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Author / Creator:Clapperton, Julie A ; Manke, Isaac A ; Lowery, Drew M ; Ho, Timmy ; Haire, Lesley F ; Yaffe, Michael B ; Smerdon, Stephen J
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2004-06, Vol.11 (6), p.512-518
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Showing 1 to 20 of 33 results

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Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis

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Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

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Uncoupling conformational states from activity in an allosteric enzyme

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KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

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IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

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High-resolution structure of a retroviral capsid hexameric amino-terminal domain

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RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

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The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage

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A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

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Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans

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The structure of the GTPase-activating domain from p50rhoGAP

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Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

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Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

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A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

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The Use of In Vitro Peptide-Library Screens in the Analysis of Phosphoserine/Threonine-Binding Domain Structure and Function

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Erratum: High-resolution structure of a retroviral capsid hexameric amino-terminal domain

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The crystal structure of NusB from Mycobacterium tuberculosis

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Support for shared ancestry of GAPs

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KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

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Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

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