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ArticlesPeer ReviewedFull Text
Spatial transcriptomics inferred from pathology whole-slide images links tumor heterogeneity to survival in breast and lung cancer
Author / Creator:Levy-Jurgenson, Alona ; Tekpli, Xavier ; Kristensen, Vessela N. ; Yakhini, Zohar
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-11, Vol.10 (1), p.18802, Article 18802
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DNA methylation at enhancers identifies distinct breast cancer lineages
Author / Creator:Fleischer, Thomas ; Tekpli, Xavier ; Mathelier, Anthony ; Wang, Shixiong ; Nebdal, Daniel ; Dhakal, Hari P. ; Sahlberg, Kristine Kleivi ; Schlichting, Ellen ; Børresen-Dale, Anne-Lise ; Borgen, Elin ; Naume, Bjørn ; Eskeland, Ragnhild ; Frigessi, Arnoldo ; Tost, Jörg ; Hurtado, Antoni ; Kristensen, Vessela N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1379-14, Article 1379
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Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response
Author / Creator:Shahrouzi, Parastoo ; Azimzade, Youness ; Brankiewicz-Kopcinska, Wioletta ; Bhatia, Sugandha ; Kunke, David ; Richard, Derek ; Tekpli, Xavier ; Kristensen, Vessela N. ; Duijf, Pascal H. G.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2024-11, Vol.26 (1), p.170-19, Article 170
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Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation
Author / Creator:Ankill, Jørgen ; Zhao, Zhi ; Tekpli, Xavier ; Kure, Elin H. ; Kristensen, Vessela N. ; Mathelier, Anthony ; Fleischer, Thomas
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2024-11, Vol.20 (11), p.e1012565
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Efficient gene expression signature for a breast cancer immuno-subtype
Author / Creator:Galili, Ben ; Tekpli, Xavier ; Kristensen, Vessela N. ; Yakhini, Zohar
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-01, Vol.16 (1), p.e0245215-e0245215
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Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
Author / Creator:Heimli, Marte ; Tennebø Flåm, Siri ; Sagsveen Hjorthaug, Hanne ; Bjørnstad, Pål Marius ; Chernigovskaya, Maria ; Le, Quy Khang ; Tekpli, Xavier ; Greiff, Victor ; Lie, Benedicte Alexandra
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-10, Vol.13 (1), p.17714-17714, Article 17714
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ArticlesPeer ReviewedFull Text
Benign breast tumors may arise on different immunological backgrounds
Author / Creator:Torland, Lilly Anne ; Lai, Xiaoran ; Kumar, Surendra ; Riis, Margit H. ; Geisler, Jürgen ; Lüders, Torben ; Tekpli, Xavier ; Kristensen, Vessela ; Sahlberg, Kristine ; Tahiri, Andliena
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2024-10, Vol.18 (10), p.2495-2509
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Loss of progesterone receptor is associated with distinct tyrosine kinase profiles in breast cancer
Author / Creator:Tahiri, Andliena ; Tekpli, Xavier ; Satheesh, Somisetty V. ; DeWijn, Rik ; Lüders, Torben ; Bukholm, Ida R. ; Hurtado, Antoni ; Geisler, Jürgen ; Kristensen, Vessela N.
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2020-10, Vol.183 (3), p.585-598
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Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Author / Creator:Aure, Miriam Ragle ; Fleischer, Thomas ; Bjørklund, Sunniva ; Ankill, Jørgen ; Castro-Mondragon, Jaime A. ; Børresen-Dale, Anne-Lise ; Tost, Jörg ; Sahlberg, Kristine K. ; Mathelier, Anthony ; Tekpli, Xavier ; Kristensen, Vessela N.
Publisher:England: BioMed Central
Journal title:Genome medicine, 2021-04, Vol.13 (1), p.72-21, Article 72
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Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
Author / Creator:Bjørklund, Sunniva Stordal ; Aure, Miriam Ragle ; Häkkinen, Jari ; Vallon-Christersson, Johan ; Kumar, Surendra ; Evensen, Katrine Bull ; Fleischer, Thomas ; Tost, Jörg ; Sahlberg, Kristine K. ; Mathelier, Anthony ; Bhanot, Gyan ; Ganesan, Shridar ; Tekpli, Xavier ; Kristensen, Vessela N.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-08, Vol.5 (1), p.834-834, Article 834
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An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Author / Creator:Tekpli, Xavier ; Lien, Tonje ; Røssevold, Andreas Hagen ; Nebdal, Daniel ; Borgen, Elin ; Ohnstad, Hege Oma ; Kyte, Jon Amund ; Vallon-Christersson, Johan ; Fongaard, Marie ; Due, Eldri Undlien ; Svartdal, Lisa Gregusson ; Sveli, My Anh Tu ; Garred, Øystein ; Frigessi, Arnoldo ; Sahlberg, Kristine Kleivi ; Sørlie, Therese ; Russnes, Hege G. ; Naume, Bjørn ; Kristensen, Vessela N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5499-14, Article 5499
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ArticlesPeer ReviewedFull Text
DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
Author / Creator:Tekpli, Xavier ; Landvik, Nina E. ; Anmarkud, Kristine H. ; Skaug, Vidar ; Haugen, Aage ; Zienolddiny, Shanbeh
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer Immunology, Immunotherapy, 2013-02, Vol.62 (2), p.337-345
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High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis
Author / Creator:Røssevold, Andreas Hagen ; Tekpli, Xavier ; Lingjærde, Ole Christian ; Russnes, Hege G. ; Vallon-Christersson, Johan ; Borgen, Elin ; Lømo, Jon ; Garred, Øystein ; Dorraji, Esmaeil ; Kristensen, Vessela N. ; Naume, Bjørn ; Kyte, Jon Amund
Publisher:London: Nature Publishing Group UK
Journal title:Communications medicine, 2025-06, Vol.5 (1), p.234
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ArticlesPeer ReviewedFull Text
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Author / Creator:Tekpli, Xavier ; Urbanucci, Alfonso ; Hashim, Adnan ; Vågbø, Cathrine B. ; Lyle, Robert ; Kringen, Marianne K. ; Staff, Anne Cathrine ; Dybedal, Ingunn ; Mills, Ian G. ; Klungland, Arne ; Staerk, Judith
Publisher:England: BioMed Central Ltd
Journal title:Epigenetics & chromatin, 2016-05, Vol.9 (1), p.21-21, Article 21
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ArticlesFull Text
Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures
Author / Creator:Osorio, Daniel ; Shahrouzi, Parastoo ; Tekpli, Xavier ; Kristensen, Vessela N ; Kuijjer, Marieke Lydia
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2024-02
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Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
Author / Creator:Levy-Jurgenson, Alona ; Tekpli, Xavier ; Zohar Yakhini
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-03
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Spatial Transcriptomics Inferred from Pathology Whole-Slide Images Links Tumor Heterogeneity to Survival in Breast and Lung Cancer
Author / Creator:Levy-Jurgenson, Alona ; Tekpli, Xavier ; Kristensen, Vessela N ; Zohar Yakhini
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-09
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Predicting Methylation from Sequence and Gene Expression Using Deep Learning with Attention
Author / Creator:Levy-Jurgenson, Alona ; Tekpli, Xavier ; Kristensen, Vessela N ; Zohar Yakhini
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-12
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Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer
Author / Creator:Ankill, Jørgen ; Miriam Ragle Aure ; Bjørklund, Sunniva ; Langberg, Severin ; Oslo Breast Cancer Research Consortium (Osbreac) ; Kristensen, Vessela N ; Vitelli, Valeria ; Tekpli, Xavier ; Fleischer, Thomas
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-04
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Crosstalk between microRNA expression and DNA methylation drive the hormone-dependent phenotype of breast cancer
Author / Creator:Miriam Ragle Aure ; Fleischer, Thomas ; Bjorklund, Sunniva ; Ankill, Jorgen ; Jaime Abraham Castro-Mondragon ; Oslo Breast Cancer Research Consortium (Osbreac) ; Borresen-Dale, Anne-Lise ; Sahlberg, Kristine K ; Mathelier, Anthony ; Tekpli, Xavier ; Kristensen, Vessela N
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-04
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Spatial transcriptomics inferred from pathology whole-slide images links tumor heterogeneity to survival in breast and lung cancer

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DNA methylation at enhancers identifies distinct breast cancer lineages

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Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

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Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation

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Efficient gene expression signature for a breast cancer immuno-subtype

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Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq

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Benign breast tumors may arise on different immunological backgrounds

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Loss of progesterone receptor is associated with distinct tyrosine kinase profiles in breast cancer

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Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer

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Subtype and cell type specific expression of lncRNAs provide insight into breast cancer

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An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment

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DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer

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High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis

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Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

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Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

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Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging

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Spatial Transcriptomics Inferred from Pathology Whole-Slide Images Links Tumor Heterogeneity to Survival in Breast and Lung Cancer

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Predicting Methylation from Sequence and Gene Expression Using Deep Learning with Attention

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Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer

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Crosstalk between microRNA expression and DNA methylation drive the hormone-dependent phenotype of breast cancer

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