An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvir...
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
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Author / Creator
OSBREAC , Tekpli, Xavier , Lien, Tonje , Røssevold, Andreas Hagen , Nebdal, Daniel , Borgen, Elin , Ohnstad, Hege Oma , Kyte, Jon Amund , Vallon-Christersson, Johan , Fongaard, Marie , Due, Eldri Undlien , Svartdal, Lisa Gregusson , Sveli, My Anh Tu , Garred, Øystein , Frigessi, Arnoldo , Sahlberg, Kristine Kleivi , Sørlie, Therese , Russnes, Hege G. , Naume, Bjørn and Kristensen, Vessela N.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated with a worse prognosis independ...
Alternative Titles
Full title
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Authors, Artists and Contributors
Author / Creator
Tekpli, Xavier
Lien, Tonje
Røssevold, Andreas Hagen
Nebdal, Daniel
Borgen, Elin
Ohnstad, Hege Oma
Kyte, Jon Amund
Vallon-Christersson, Johan
Fongaard, Marie
Due, Eldri Undlien
Svartdal, Lisa Gregusson
Sveli, My Anh Tu
Garred, Øystein
Frigessi, Arnoldo
Sahlberg, Kristine Kleivi
Sørlie, Therese
Russnes, Hege G.
Naume, Bjørn
Kristensen, Vessela N.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_77641556908e44e9aa2cd197f5b2e87b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77641556908e44e9aa2cd197f5b2e87b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13329-5