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An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvir...

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvir...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77641556908e44e9aa2cd197f5b2e87b

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment

About this item

Full title

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-12, Vol.10 (1), p.5499-14, Article 5499

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated with a worse prognosis independ...

Alternative Titles

Full title

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_77641556908e44e9aa2cd197f5b2e87b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77641556908e44e9aa2cd197f5b2e87b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13329-5

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