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Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial
Author / Creator:Motzer, Robert J, Dr ; Hutson, Thomas E, DO ; Glen, Hilary, MD ; Michaelson, M Dror, MD ; Molina, Ana, MD ; Eisen, Timothy, Prof ; Jassem, Jacek, Prof ; Zolnierek, Jakub, MD ; Maroto, Jose Pablo, MD ; Mellado, Begoña, MD ; Melichar, Bohuslav, Prof ; Tomasek, Jiri, MD ; Kremer, Alton, MD ; Kim, Han-Joo, PhD ; Wood, Karen, PhD ; Dutcus, Corina, MD ; Larkin, James, FRCP
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-11, Vol.16 (15), p.1473-1482
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Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study
Author / Creator:Yao, James C, Dr ; Fazio, Nicola, MD ; Singh, Simron, MD ; Buzzoni, Roberto, MD ; Carnaghi, Carlo, MD ; Wolin, Edward, MD ; Tomasek, Jiri, MD ; Raderer, Markus, MD ; Lahner, Harald, MD ; Voi, Maurizio, MD ; Pacaud, Lida Bubuteishvili, MD ; Rouyrre, Nicolas, MSc ; Sachs, Carolin, RN ; Valle, Juan W, MD ; Fave, Gianfranco Delle, MD ; Van Cutsem, Eric, MD ; Tesselaar, Margot, MD ; Shimada, Yasuhiro, MD ; Oh, Do-Youn, MD ; Strosberg, Jonathan, MD ; Kulke, Matthew H, MD ; Pavel, Marianne E, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-03, Vol.387 (10022), p.968-977
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Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab
Author / Creator:Fuchs, Charles S ; Tabernero, Josep ; Tomášek, Jiří ; Chau, Ian ; Melichar, Bohuslav ; Safran, Howard ; Tehfe, Mustapha A ; Filip, Dumitru ; Topuzov, Eldar ; Schlittler, Luis ; Udrea, Anghel Adrian ; Campbell, William ; Brincat, Stephen ; Emig, Michael ; Melemed, Symantha A ; Hozak, Rebecca R ; Ferry, David ; Caldwell, C William ; Ajani, Jaffer A
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2016-10, Vol.115 (8), p.974-982
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Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
Author / Creator:Fuchs, Charles S, Dr Prof ; Tomasek, Jiri, MD ; Yong, Cho Jae, Prof ; Dumitru, Filip, MD ; Passalacqua, Rodolfo, MD ; Goswami, Chanchal, Prof ; Safran, Howard, Prof ; dos Santos, Lucas Vieira, MD ; Aprile, Giuseppe, MD ; Ferry, David R, Prof ; Melichar, Bohuslav, Prof ; Tehfe, Mustapha, MD ; Topuzov, Eldar, Prof ; Zalcberg, John Raymond, Prof ; Chau, Ian, MD ; Campbell, William, Prof ; Sivanandan, Choondal, MD ; Pikiel, Joanna, MD ; Koshiji, Minori, MD ; Hsu, Yanzhi, PhD ; Liepa, Astra M, PharmD ; Gao, Ling, PhD ; Schwartz, Jonathan D, MD ; Tabernero, Josep, MD
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2014-01, Vol.383 (9911), p.31-39
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Everolimus in advanced, progressive, well‐differentiated, non‐functional neuroendocrine tumors: RADIANT‐4 lung subgroup analysis
Author / Creator:Fazio, Nicola ; Buzzoni, Roberto ; Delle Fave, Gianfranco ; Tesselaar, Margot E. ; Wolin, Edward ; Van Cutsem, Eric ; Tomassetti, Paola ; Strosberg, Jonathan ; Voi, Maurizio ; Bubuteishvili‐Pacaud, Lida ; Ridolfi, Antonia ; Herbst, Fabian ; Tomasek, Jiri ; Singh, Simron ; Pavel, Marianne ; Kulke, Matthew H. ; Valle, Juan W. ; Yao, James C.
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-01, Vol.109 (1), p.174-181
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Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study
Author / Creator:Krämer, Alwin ; Bochtler, Tilmann ; Pauli, Chantal ; Shiu, Kai-Keen ; Cook, Natalie ; de Menezes, Juliana Janoski ; Pazo-Cid, Roberto A ; Losa, Ferran ; Robbrecht, Debbie GJ ; Tomášek, Jiří ; Arslan, Cagatay ; Özgüroğlu, Mustafa ; Stahl, Michael ; Bigot, Frédéric ; Kim, Sun Young ; Naito, Yoichi ; Italiano, Antoine ; Chalabi, Nasséra ; Durán-Pacheco, Gonzalo ; Michaud, Chantal ; Scarato, Jeremy ; Thomas, Marlene ; Ross, Jeffrey S ; Moch, Holger ; Mileshkin, Linda
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2024-08, Vol.404 (10452), p.527-539
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Panitumumab Use in Metastatic Colorectal Cancer and Patterns of KRAS Testing: Results from a Europe-Wide Physician Survey and Medical Records Review
Author / Creator:Trojan, Jörg ; Mineur, Laurent ; Tomášek, Jiří ; Rouleau, Etienne ; Fabian, Pavel ; de Maglio, Giovanna ; García-Alfonso, Pilar ; Aprile, Giuseppe ; Taylor, Aliki ; Kafatos, George ; Downey, Gerald ; Terwey, Jan-Henrik ; van Krieken, J. Han
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0140717-e0140717
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Everolimus in Neuroendocrine Tumors of the Gastrointestinal Tract and Unknown Primary
Author / Creator:Singh, Simron ; Carnaghi, Carlo ; Buzzoni, Roberto ; Pommier, Rodney F. ; Raderer, Markus ; Tomasek, Jiri ; Lahner, Harald ; Valle, Juan W. ; Voi, Maurizio ; Bubuteishvili-Pacaud, Lida ; Lincy, Jeremie ; Wolin, Edward ; Okita, Natsuko ; Libutti, Steven K. ; Oh, Do-Youn ; Kulke, Matthew ; Strosberg, Jonathan ; Yao, James C. ; Pavel, Marianne E. ; Fazio, Nicola
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Neuroendocrinology, 2018-04, Vol.106 (3), p.211-220
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Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review
Author / Creator:Han van Krieken, J. ; Kafatos, George ; Bennett, James ; Mineur, Laurent ; Tomášek, Jiří ; Rouleau, Etienne ; Fabian, Pavel ; De Maglio, Giovanna ; García-Alfonso, Pilar ; Aprile, Giuseppe ; Parkar, Parijan ; Downey, Gerald ; Demonty, Gaston ; Trojan, Jörg
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2017-11, Vol.17 (1), p.798-798, Article 798
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study
Author / Creator:Dasari, Arvind ; Lonardi, Sara ; Garcia-Carbonero, Rocio ; Elez, Elena ; Yoshino, Takayuki ; Sobrero, Alberto ; Yao, James ; García-Alfonso, Pilar ; Kocsis, Judit ; Cubillo Gracian, Antonio ; Sartore-Bianchi, Andrea ; Satoh, Taroh ; Randrian, Violaine ; Tomasek, Jiri ; Chong, Geoff ; Paulson, Andrew Scott ; Masuishi, Toshiki ; Jones, Jeremy ; Csőszi, Tibor ; Cremolini, Chiara ; Ghiringhelli, Francois ; Shergill, Ardaman ; Hochster, Howard S ; Krauss, John ; Bassam, Ali ; Ducreux, Michel ; Elme, Anneli ; Faugeras, Laurence ; Kasper, Stefan ; Van Cutsem, Eric ; Arnold, Dirk ; Nanda, Shivani ; Yang, Zhao ; Schelman, William R ; Kania, Marek ; Tabernero, Josep ; Eng, Cathy
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2023-07, Vol.402 (10395), p.41-53
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer: safety analysis of FRESCO-2
Author / Creator:Eng, Cathy ; Dasari, Arvind ; Lonardi, Sara ; Garcia-Carbonero, Rocio ; Elez, Elena ; Yoshino, Takayuki ; Sobrero, Alberto ; Yao, James ; Garcia-Alfonso, Pilar ; Kocsis, Judit ; Gracian, Antonio Cubillo ; Sartore-Bianchi, Andrea ; Satoh, Taroh ; Randrian, Violaine ; Tomasek, Jiri ; Chong, Geoff ; Yang, Zhao ; Guevara, Ferdinand ; Schelman, William ; Pallai, Rajash ; Tabernero, Josep
Publisher:England: Oxford University Press
Journal title:The oncologist (Dayton, Ohio), 2025-03, Vol.30 (3)
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Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre,...
Author / Creator:Pavel, Marianne E ; Singh, Simron ; Strosberg, Jonathan R ; Bubuteishvili-Pacaud, Lida ; Degtyarev, Evgeny ; Neary, Maureen P ; Carnaghi, Carlo ; Tomasek, Jiri ; Wolin, Edward ; Raderer, Markus ; Lahner, Harald ; Valle, Juan W ; Pommier, Rodney ; Van Cutsem, Eric ; Tesselaar, Margot E T ; Fave, Gianfranco Delle ; Buzzoni, Roberto ; Hunger, Matthias ; Eriksson, Jennifer ; Cella, David ; Ricci, Jean-François ; Fazio, Nicola ; Kulke, Matthew H ; Yao, James C
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-10, Vol.18 (10), p.1411-1422
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Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours
Author / Creator:Raymond, Eric ; Kulke, Matthew H. ; Qin, Shukui ; Yu, Xianjun ; Schenker, Michael ; Cubillo, Antonio ; Lou, Wenhui ; Tomasek, Jiri ; Thiis-Evensen, Espen ; Xu, Jian-Ming ; Croitoru, Adina E. ; Khasraw, Mustafa ; Sedlackova, Eva ; Borbath, Ivan ; Ruff, Paul ; Oberstein, Paul E. ; Ito, Tetsuhide ; Jia, Liqun ; Hammel, Pascal ; Shen, Lin ; Shrikhande, Shailesh V. ; Shen, Yali ; Sufliarsky, Jozef ; Khan, Gazala N. ; Morizane, Chigusa ; Galdy, Salvatore ; Khosravan, Reza ; Fernandez, Kathrine C. ; Rosbrook, Brad ; Fazio, Nicola
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Neuroendocrinology, 2018-01, Vol.107 (3), p.237-245
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Pharmacogenomic analyses of sunitinib in patients with pancreatic neuroendocrine tumors
Author / Creator:Fazio, Nicola ; Martini, Jean-Francois ; Croitoru, Adina E ; Schenker, Michael ; Li, Sherry ; Rosbrook, Brad ; Fernandez, Kathrine ; Tomasek, Jiri ; Thiis-Evensen, Espen ; Kulke, Matthew ; Raymond, Eric
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2019-06, Vol.15 (17), p.1997-2007
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Regorafenib in the Real-Life Clinical Practice: Data from the Czech Registry
Author / Creator:Kopeckova, Katerina ; Buchler, Tomas ; Bortlicek, Zbynek ; Hejduk, Karel ; Chloupkova, Renata ; Melichar, Bohuslav ; Pokorna, Petra ; Tomasek, Jiri ; Linke, Zdenek ; Petruzelka, Lubos ; Kiss, Igor ; Prausova, Jana
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2017-02, Vol.12 (1), p.89-95
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Efficacy and safety of bevacizumab in elderly patients with metastatic colorectal cancer: results from the Czech population-based registry
Author / Creator:Slavicek, Lubomir ; Pavlik, Tomas ; Tomasek, Jiri ; Bortlicek, Zbynek ; Buchler, Tomas ; Melichar, Bohuslav ; Vyzula, Rostislav ; Prausova, Jana ; Finek, Jindrich ; Majek, Ondrej ; Dusek, Ladislav
Publisher:England: BioMed Central
Journal title:BMC gastroenterology, 2014-03, Vol.14 (1), p.53-53, Article 53
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Everolimus for the treatment of advanced, nonfunctional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study
Author / Creator:Yao, James C ; Fazio, Nicola ; Singh, Simron ; Buzzoni, Roberto ; Carnaghi, Carlo ; Wolin, Edward ; Tomasek, Jiri ; Raderer, Markus ; Lahner, Harald ; Voi, Maurizio ; Pacaud, Lida Bubuteishvili ; Rouyrre, Nicolas ; Sachs, Carolin ; Valle, Juan W ; Fave, Gianfranco Delle ; Van Cutsem, Eric ; Tesselaar, Margot ; Shimada, Yasuhiro ; Oh, Do-Youn ; Strosberg, Jonathan ; Kulke, Matthew H ; Pavel, Marianne E
Journal title:The Lancet (British edition), 2015-12, Vol.387 (10022), p.968-977
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Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma
Author / Creator:Motzer, Robert ; Alekseev, Boris ; Rha, Sun-Young ; Porta, Camillo ; Eto, Masatoshi ; Powles, Thomas ; Grünwald, Viktor ; Hutson, Thomas E ; Kopyltsov, Evgeny ; Méndez-Vidal, María J ; Kozlov, Vadim ; Alyasova, Anna ; Hong, Sung-Hoo ; Kapoor, Anil ; Alonso Gordoa, Teresa ; Merchan, Jaime R ; Winquist, Eric ; Maroto, Pablo ; Goh, Jeffrey C ; Kim, Miso ; Gurney, Howard ; Patel, Vijay ; Peer, Avivit ; Procopio, Giuseppe ; Takagi, Toshio ; Melichar, Bohuslav ; Rolland, Frederic ; De Giorgi, Ugo ; Wong, Shirley ; Bedke, Jens ; Schmidinger, Manuela ; Dutcus, Corina E ; Smith, Alan D ; Dutta, Lea ; Mody, Kalgi ; Perini, Rodolfo F ; Xing, Dongyuan ; Choueiri, Toni K
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2021-04, Vol.384 (14), p.1289-1300
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Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy
Author / Creator:Ravaud, Alain ; Motzer, Robert J ; Pandha, Hardev S ; George, Daniel J ; Pantuck, Allan J ; Patel, Anup ; Chang, Yen-Hwa ; Escudier, Bernard ; Donskov, Frede ; Magheli, Ahmed ; Carteni, Giacomo ; Laguerre, Brigitte ; Tomczak, Piotr ; Breza, Jan ; Gerletti, Paola ; Lechuga, Mariajose ; Lin, Xun ; Martini, Jean-Francois ; Ramaswamy, Krishnan ; Casey, Michelle ; Staehler, Michael ; Patard, Jean-Jacques
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-12, Vol.375 (23), p.2246-2254
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Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer
Author / Creator:Andre, Thierry ; Elez, Elena ; Van Cutsem, Eric ; Jensen, Lars Henrik ; Bennouna, Jaafar ; Mendez, Guillermo ; Schenker, Michael ; de la Fouchardiere, Christelle ; Limon, Maria Luisa ; Yoshino, Takayuki ; Li, Jin ; Lenz, Heinz-Josef ; Manzano Mozo, Jose Luis ; Tortora, Giampaolo ; Garcia-Carbonero, Rocio ; Dahan, Laetitia ; Chalabi, Myriam ; Joshi, Rohit ; Goekkurt, Eray ; Braghiroli, Maria Ignez ; Cil, Timucin ; Cela, Elvis ; Chen, Tian ; Lei, Ming ; Dixon, Matthew ; Abdullaev, Sandzhar ; Lonardi, Sara
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-11, Vol.391 (21), p.2014-2026
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Showing 1 to 20 of 20 results

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Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial

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Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study

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Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab

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Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial

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Everolimus in advanced, progressive, well‐differentiated, non‐functional neuroendocrine tumors: RADIANT‐4 lung subgroup analysis

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Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study

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Panitumumab Use in Metastatic Colorectal Cancer and Patterns of KRAS Testing: Results from a Europe-Wide Physician Survey and Medical Records Review

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Everolimus in Neuroendocrine Tumors of the Gastrointestinal Tract and Unknown Primary

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Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review

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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study

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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer: safety analysis of FRESCO-2

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Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre,...

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Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours

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Pharmacogenomic analyses of sunitinib in patients with pancreatic neuroendocrine tumors

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Regorafenib in the Real-Life Clinical Practice: Data from the Czech Registry

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Efficacy and safety of bevacizumab in elderly patients with metastatic colorectal cancer: results from the Czech population-based registry

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Everolimus for the treatment of advanced, nonfunctional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study

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Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma

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Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy

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Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer

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