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161 results for Triazoles+-+metabolism

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ArticlesPeer ReviewedFull Text
Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
Author / Creator:Savile, Christopher K. ; Janey, Jacob M. ; Mundorff, Emily C. ; Moore, Jeffrey C. ; Tam, Sarena ; Jarvis, William R. ; Colbeck, Jeffrey C. ; Krebber, Anke ; Fleitz, Fred J. ; Brands, Jos ; Devine, Paul N. ; Huisman, Gjalt W. ; Hughes, Gregory J.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5989), p.305-309
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An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
Author / Creator:Qi, Wei ; Zhao, Kehao ; Gu, Justin ; Huang, Ying ; Wang, Youzhen ; Zhang, Hailong ; Zhang, Man ; Zhang, Jeff ; Yu, Zhengtian ; Li, Ling ; Teng, Lin ; Chuai, Shannon ; Zhang, Chao ; Zhao, Mengxi ; Chan, HoMan ; Chen, Zijun ; Fang, Douglas ; Fei, Qi ; Feng, Leying ; Feng, Lijian ; Gao, Yuan ; Ge, Hui ; Ge, Xinjian ; Li, Guobin ; Lingel, Andreas ; Lin, Ying ; Liu, Yueqin ; Luo, Fangjun ; Shi, Minlong ; Wang, Long ; Wang, Zhaofu ; Yu, Yanyan ; Zeng, Jue ; Zeng, Chenhui ; Zhang, Lijun ; Zhang, Qiong ; Zhou, Shaolian ; Oyang, Counde ; Atadja, Peter ; Li, En
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-04, Vol.13 (4), p.381-388
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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
Author / Creator:Liu, Wei ; Chun, Eugene ; Thompson, Aaron A. ; Chubukov, Pavel ; Xu, Fei ; Katritch, Vsevolod ; Han, Gye Won ; Roth, Christopher B. ; Heitman, Laura H. ; IJzerman, Adriaan P. ; Cherezov, Vadim ; Stevens, Raymond C.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-07, Vol.337 (6091), p.232-236
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Transcriptomic analysis of Vigna radiata in response to chilling stress and uniconazole application
Author / Creator:Hu, Hanqiao ; Feng, Naijie ; Shen, Xuefeng ; Zhao, Liming ; Zheng, Dianfeng
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2022-03, Vol.23 (1), p.205-205, Article 205
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Structure of an Agonist-Bound Human A2A Adenosine Receptor
Author / Creator:FEI XU ; HUIXIAN WU ; KATRITCH, Vsevolod ; GYE WON HAN ; JACOBSON, Kenneth A ; GAO, Zhan-Guo ; CHEREZOV, Vadim ; STEVENS, Raymond C
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6027), p.322-327
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Precision is essential for efficient catalysis in an evolved Kemp eliminase
Author / Creator:Blomberg, Rebecca ; Kries, Hajo ; Pinkas, Daniel M. ; Mittl, Peer R. E. ; Grütter, Markus G. ; Privett, Heidi K. ; Mayo, Stephen L. ; Hilvert, Donald
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-11, Vol.503 (7476), p.418-421
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Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation
Author / Creator:Hong, Chuan ; Byrne, Noel J. ; Zamlynny, Beata ; Tummala, Srivanya ; Xiao, Li ; Shipman, Jennifer M. ; Partridge, Andrea T. ; Minnick, Christina ; Breslin, Michael J. ; Rudd, Michael T. ; Stachel, Shawn J. ; Rada, Vanessa L. ; Kern, Jeffrey C. ; Armacost, Kira A. ; Hollingsworth, Scott A. ; O’Brien, Julie A. ; Hall, Dawn L. ; McDonald, Terrence P. ; Strickland, Corey ; Brooun, Alexei ; Soisson, Stephen M. ; Hollenstein, Kaspar
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.815-11, Article 815
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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant
Author / Creator:Yin, Jie ; Mobarec, Juan Carlos ; Kolb, Peter ; Rosenbaum, Daniel M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-03, Vol.519 (7542), p.247-250
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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
Author / Creator:Lebon, Guillaume ; Warne, Tony ; Edwards, Patricia C. ; Bennett, Kirstie ; Langmead, Christopher J. ; Leslie, Andrew G. W. ; Tate, Christopher G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-05, Vol.474 (7352), p.521-525
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Self-reproducing catalyst drives repeated phospholipid synthesis and membrane growth
Author / Creator:Hardy, Michael D. ; Yang, Jun ; Selimkhanov, Jangir ; Cole, Christian M. ; Tsimring, Lev S. ; Devaraj, Neal K.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8187-8192
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Azole resistance in Aspergillus fumigatus : a side-effect of environmental fungicide use?
Author / Creator:Verweij, Paul E, Dr ; Snelders, Eveline, MSc ; Kema, Gert HJ, PhD ; Mellado, Emilia, PhD ; Melchers, Willem JG, PhD
Publisher:London: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2009-12, Vol.9 (12), p.789-795
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Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
Author / Creator:Song, Ziyuan ; Mansbach, Rachael A. ; He, Hua ; Shih, Kuo-Chih ; Baumgartner, Ryan ; Zheng, Nan ; Ba, Xiaochu ; Huang, Yinzhao ; Mani, Deepak ; Liu, Yun ; Lin, Yao ; Nieh, Mu-Ping ; Ferguson, Andrew L. ; Yin, Lichen ; Cheng, Jianjun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-07, Vol.8 (1), p.92-8, Article 92
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Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2
Author / Creator:Scott, Daniel C. ; Dharuman, Suresh ; Griffith, Elizabeth ; Chai, Sergio C. ; Ronnebaum, Jarrid ; King, Moeko T. ; Tangallapally, Rajendra ; Lee, Chan ; Gee, Clifford T. ; Yang, Lei ; Li, Yong ; Loudon, Victoria C. ; Lee, Ha Won ; Ochoada, Jason ; Miller, Darcie J. ; Jayasinghe, Thilina ; Paulo, Joao A. ; Elledge, Stephen J. ; Harper, J. Wade ; Chen, Taosheng ; Lee, Richard E. ; Schulman, Brenda A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8829-19, Article 8829
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An artificial primitive mimic of the Gramicidin-A channel
Author / Creator:Barboiu, Mihail ; Le Duc, Yann ; Gilles, Arnaud ; Cazade, Pierre-André ; Michau, Mathieu ; Marie Legrand, Yves ; van der Lee, Arie ; Coasne, Benoît ; Parvizi, Paria ; Post, Joshua ; Fyles, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-06, Vol.5 (1), p.4142-4142, Article 4142
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Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction
Author / Creator:Rozhon, Wilfried ; Akter, Sonia ; Fernandez, Atiara ; Poppenberger, Brigitte
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-11, Vol.24 (23), p.4372
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Uptake, translocation, and subcellular distribution of three triazole pesticides in rice
Author / Creator:Li, Haocong ; Li, Yong ; Wang, Wenfeng ; Wan, Qun ; Yu, Xiangyang ; Sun, Wenjing
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Environmental science and pollution research international, 2022-04, Vol.29 (17), p.25581-25590
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Enantioselective Toxic Effects of Prothioconazole toward Scenedesmus obliquus
Author / Creator:Xiang, Qingqing ; Zhou, Ying ; Tan, Chengxia
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4774
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A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site
Author / Creator:Hardwicke, Mary Ann ; Rendina, Alan R ; Williams, Shawn P ; Moore, Michael L ; Wang, Liping ; Krueger, Julie A ; Plant, Ramona N ; Totoritis, Rachel D ; Zhang, Guofeng ; Briand, Jacques ; Burkhart, William A ; Brown, Kristin K ; Parrish, Cynthia A
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2014-09, Vol.10 (9), p.774-779
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Difenoconazole Degradation by Novel Microbial Consortium TA01: Metabolic Pathway and Microbial Community Analysis
Author / Creator:Wang, Tianyue ; Sui, Jingyi ; Zhou, Yi ; Wang, Liping ; Yang, Jia ; Chen, Feiyu ; Cui, Xiuming ; Yang, Ye ; Zhang, Wenping
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-03, Vol.26 (7), p.3142
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Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
Author / Creator:Michino, Mayako ; Abola, Enrique ; Brooks, Charles L. ; Dixon, J. Scott ; Moult, John ; Stevens, Raymond C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2009-06, Vol.8 (6), p.455-463
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Showing 1 to 20 of 161 results

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Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

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An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

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Transcriptomic analysis of Vigna radiata in response to chilling stress and uniconazole application

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Structure of an Agonist-Bound Human A2A Adenosine Receptor

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Precision is essential for efficient catalysis in an evolved Kemp eliminase

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Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation

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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

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Self-reproducing catalyst drives repeated phospholipid synthesis and membrane growth

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Azole resistance in Aspergillus fumigatus : a side-effect of environmental fungicide use?

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Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

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Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2

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An artificial primitive mimic of the Gramicidin-A channel

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Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction

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Uptake, translocation, and subcellular distribution of three triazole pesticides in rice

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Enantioselective Toxic Effects of Prothioconazole toward Scenedesmus obliquus

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A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site

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Difenoconazole Degradation by Novel Microbial Consortium TA01: Metabolic Pathway and Microbial Community Analysis

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Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008

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