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Combining CD40 agonist mitazalimab with mFOLFIRINOX in previously untreated metastatic pancreatic ductal adenocarcinoma (OPTIMIZE-1): a single-arm, multicentre phase 1b/2 study
Author / Creator:Van Laethem, Jean-Luc, Prof ; Borbath, Ivan, Prof ; Prenen, Hans, Prof ; Geboes, Karen Paula, Prof ; Lambert, Aurélien, MD ; Mitry, Emmanuel, MD ; Cassier, Philippe Alexandre, MD ; Blanc, Jean-Frédéric, Prof ; Pilla, Lorenzo, MD ; Batlle, Jaime Feliu, MD ; Garrote, Mercedes Rodriguez, MD ; Pazo-Cid, Roberto Antonio, MD ; Gallego, Inmaculada, MD ; Smith, Karin Enell, PhD ; Ellmark, Peter, PhD ; Pico de Coaña, Yago, PhD ; Ambarkhane, Sumeet Vijay, MD ; Macarulla, Teresa, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-07, Vol.25 (7), p.853-864
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Cancer patients’ behaviors and attitudes toward natural health products
Author / Creator:Schils, Audrey ; Lechon, Anne-Sophie ; Rondeaux, Sarah ; Souard, Florence ; Van Laethem, Jean-Luc ; Pochet, Stephanie ; Mathieu, Veronique ; De Vriese, Carine
Publisher:England: BioMed Central
Journal title:BMC complementary and alternative medicine, 2023-12, Vol.23 (1), p.442-442, Article 442
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Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study
Author / Creator:Bosset, Jean-François, Prof ; Calais, Gilles, Prof ; Mineur, Laurent, MD ; Maingon, Philippe, Prof ; Stojanovic-Rundic, Suzana, MD ; Bensadoun, René-Jean, Prof ; Bardet, Etienne, MD ; Beny, Alexander, MD ; Ollier, Jean-Claude, MD ; Bolla, Michel, Prof ; Marchal, Dominique, MD ; Van Laethem, Jean-Luc, Prof ; Klein, Vincent, MD ; Giralt, Jordi, MD ; Clavère, Pierre, Prof ; Glanzmann, Christoph, Prof ; Cellier, Patrice, MD ; Collette, Laurence, PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-02, Vol.15 (2), p.184-190
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Vagal nerve activity predicts overall survival in metastatic pancreatic cancer, mediated by inflammation
Author / Creator:Couck, Marijke De ; Maréchal, Raphaël ; Moorthamers, Sofie ; Laethem, Jean-Luc Van ; Gidron, Yori
Publisher:Netherlands: Elsevier Ltd
Journal title:Cancer epidemiology, 2016-02, Vol.40, p.47-51
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The lack of selection criteria for surgery in patients with non-colorectal non-neuroendocrine liver metastases
Author / Creator:Bohlok, Ali ; Lucidi, Valerio ; Bouazza, Fikri ; Daher, Ali ; Germanova, Desislava ; Van Laethem, Jean Luc ; Hendlisz, Alain ; Donckier, Vincent
Publisher:England: BioMed Central Ltd
Journal title:World journal of surgical oncology, 2020-05, Vol.18 (1), p.106-106, Article 106
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Esophageal cancer: Outcome and potential benefit of esophagectomy in elderly patients
Author / Creator:Laurent, Adeline ; Marechal, Raphael ; Farinella, Eleonora ; Bouazza, Fikri ; Charaf, Yassine ; Gay, France ; Van Laethem, Jean‐Luc ; Gonsette, Kimberly ; El Nakadi, Issam
Publisher:Melbourne: John Wiley & Sons Australia, Ltd
Journal title:Thoracic cancer, 2022-10, Vol.13 (19), p.2699-2710
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A real-world analysis on the efficacy and tolerability of liposomal irinotecan plus 5-fluorouracil and folinic acid in metastatic pancreatic ductal adenocarcinoma in Belgium
Author / Creator:Verbruggen, Lise ; Verheggen, Lisa ; Vanhoutte, Greetje ; Loly, Catherine ; Lybaert, Willem ; Borbath, Ivan ; Vergauwe, Philippe ; Hendrickx, Koen ; Debeuckelaere, Celine ; de Haar-Holleman, Amy ; Van Laethem, Jean-Luc ; Peeters, Marc
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2023-01, Vol.15, p.17588359231181500-17588359231181500
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Isotoxic high-dose stereotactic body radiotherapy integrated in a total multimodal neoadjuvant strategy for the treatment of localized pancreatic ductal adenocarcinoma
Author / Creator:Bouchart, Christelle ; Engelholm, Jean-Luc ; Closset, Jean ; Navez, Julie ; Loi, Patrizia ; Gökburun, Yeter ; De Grez, Thierry ; Mans, Laura ; Hendlisz, Alain ; Bali, Maria Antonietta ; Eisendrath, Pierre ; Van Gestel, Dirk ; Hein, Matthieu ; Moretti, Luigi ; Van Laethem, Jean-Luc
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2021, Vol.13, p.17588359211045860
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Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients
Author / Creator:Maréchal, Raphaël ; De Schutter, Jef ; Nagy, Nathalie ; Demetter, Pieter ; Lemmers, Arnaud ; Devière, Jacques ; Salmon, Isabelle ; Tejpar, Sabine ; Van Laethem, Jean-Luc
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2010-06, Vol.10 (1), p.340-340, Article 340
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ArticlesPeer ReviewedFull Text
Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas
Author / Creator:Van Damme, Nancy ; Deron, Philippe ; Van Roy, Nadine ; Demetter, Pieter ; Bols, Alain ; Dorpe, Jo Van ; Baert, Filip ; Van Laethem, Jean-Luc ; Speleman, Franki ; Pauwels, Patrick ; Peeters, Marc
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2010-05, Vol.10 (1), p.189-189, Article 189
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ArticlesPeer ReviewedFull Text
Aquaporins Involvement in Pancreas Physiology and in Pancreatic Diseases
Author / Creator:Arsenijevic, Tatjana ; Perret, Jason ; Van Laethem, Jean-Luc ; Delporte, Christine
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-10, Vol.20 (20), p.5052
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ArticlesPeer ReviewedFull Text
What Should Guide the Performance of Venous Resection During Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma with Venous Contact?
Author / Creator:Navez, Julie ; Bouchart, Christelle ; Lorenzo, Diane ; Bali, Maria Antonietta ; Closset, Jean ; van Laethem, Jean-Luc
Publisher:Cham: Springer International Publishing
Journal title:Annals of surgical oncology, 2021-10, Vol.28 (11), p.6211-6222
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Personalized medicine in pancreatic cancer: the revolution has begun
Author / Creator:Maréchal, Raphaël ; Puleo, Francesco ; Demols, Anne ; Verset, Gontran ; Laethem, Jean-Luc Van
Publisher:England: Future Medicine Ltd
Journal title:Personalized medicine, 2015-09, Vol.12 (5), p.515-523
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Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial
Author / Creator:Taieb, Julien, Prof ; Tabernero, Josep, Prof ; Mini, Enrico, Prof ; Subtil, Fabien, PhD ; Folprecht, Gunnar, MD ; Van Laethem, Jean-Luc, Prof ; Thaler, Josef, Prof ; Bridgewater, John, MD ; Petersen, Lone Nørgård, Prof ; Blons, Hélène, PhD ; Collette, Laurence, PhD ; Van Cutsem, Eric, Prof ; Rougier, Philippe, Prof ; Salazar, Ramon, Prof ; Bedenne, Laurent, Prof ; Emile, Jean-François, Prof ; Laurent-Puig, Pierre, Prof ; Lepage, Come, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-07, Vol.15 (8), p.862-873
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Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials
Author / Creator:Charette, Nicolas ; Vandeputte, Caroline ; Ameye, Lieveke ; Bogaert, Camille Van ; Krygier, Jonathan ; Guiot, Thomas ; Deleporte, Amélie ; Delaunoit, Thierry ; Geboes, Karen ; Van Laethem, Jean-Luc ; Peeters, Marc ; Demolin, Gauthier ; Holbrechts, Stéphane ; Flamen, Patrick ; Paesmans, Marianne ; Hendlisz, Alain
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2019-02, Vol.19 (1), p.134-134, Article 134
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Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study
Author / Creator:Santoro, Armando, MD ; Rimassa, Lorenza, Dr ; Borbath, Ivan, MD ; Daniele, Bruno, MD ; Salvagni, Stefania, MD ; Van Laethem, Jean Luc, Prof ; Van Vlierberghe, Hans, MD ; Trojan, Jörg, Prof ; Kolligs, Frank T, Prof ; Weiss, Alan, Prof ; Miles, Steven, MD ; Gasbarrini, Antonio, Prof ; Lencioni, Monica, MD ; Cicalese, Luca, MD ; Sherman, Morris, MD ; Gridelli, Cesare, MD ; Buggisch, Peter, MD ; Gerken, Guido, Prof ; Schmid, Roland M, Prof ; Boni, Corrado, MD ; Personeni, Nicola, MD ; Hassoun, Ziad, MD ; Abbadessa, Giovanni, MD ; Schwartz, Brian, MD ; Von Roemeling, Reinhard, MD ; Lamar, Maria E, BA ; Chen, Yinpu, PhD ; Porta, Camillo, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013, Vol.14 (1), p.55-63
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Association of post-operative CEA with survival and oxaliplatin benefit in patients with stage II colon cancer: a post hoc analysis of the MOSAIC trial
Author / Creator:Auclin, Edouard ; André, Thierry ; Taieb, Julien ; Banzi, Maria ; Van Laethem, Jean-Luc ; Tabernero, Josep ; Hickish, Tamas ; de Gramont, Aimery ; Vernerey, Dewi
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2019-08, Vol.121 (4), p.312-317
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CDK4/6 Inhibitors in Pancreatobiliary Cancers: Opportunities and Challenges
Author / Creator:Arsenijevic, Tatjana ; Coulonval, Katia ; Raspé, Eric ; Demols, Anne ; Roger, Pierre P. ; Van Laethem, Jean-Luc
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2023-02, Vol.15 (3), p.968
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Combination, Modulation and Interplay of Modern Radiotherapy with the Tumor Microenvironment and Targeted Therapies in Pancreatic Cancer: Which Candidates to Boost Radiotherapy?
Author / Creator:Benkhaled, Sofian ; Peters, Cedric ; Jullian, Nicolas ; Arsenijevic, Tatjana ; Navez, Julie ; Van Gestel, Dirk ; Moretti, Luigi ; Van Laethem, Jean-Luc ; Bouchart, Christelle
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2023-01, Vol.15 (3), p.768
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Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease
Author / Creator:Martens, Sandrina ; Coolens, Katarina ; Van Bulck, Mathias ; Arsenijevic, Tatjana ; Casamitjana, Joan ; Fernandez Ruiz, Angel ; El Kaoutari, Abdessamad ; Martinez de Villareal, Jaime ; Madhloum, Hediel ; Esni, Farzad ; Heremans, Yves ; Leuckx, Gunter ; Heimberg, Harry ; Bouwens, Luc ; Jacquemin, Patrick ; De Paep, Diedert Luc ; in't Veld, Peter ; D'Haene, Nicky ; Bouchart, Christelle ; Dusetti, Nelson ; Van Laethem, Jean-Luc ; Waelput, Wim ; Lefesvre, Pierre ; Real, Francisco X ; Rovira, Meritxell ; Rooman, Ilse
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2022-10, Vol.71 (10), p.2030-2042
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Combining CD40 agonist mitazalimab with mFOLFIRINOX in previously untreated metastatic pancreatic ductal adenocarcinoma (OPTIMIZE-1): a single-arm, multicentre phase 1b/2 study

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Cancer patients’ behaviors and attitudes toward natural health products

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Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study

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Vagal nerve activity predicts overall survival in metastatic pancreatic cancer, mediated by inflammation

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The lack of selection criteria for surgery in patients with non-colorectal non-neuroendocrine liver metastases

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Esophageal cancer: Outcome and potential benefit of esophagectomy in elderly patients

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A real-world analysis on the efficacy and tolerability of liposomal irinotecan plus 5-fluorouracil and folinic acid in metastatic pancreatic ductal adenocarcinoma in Belgium

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Isotoxic high-dose stereotactic body radiotherapy integrated in a total multimodal neoadjuvant strategy for the treatment of localized pancreatic ductal adenocarcinoma

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Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients

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Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas

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Aquaporins Involvement in Pancreas Physiology and in Pancreatic Diseases

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What Should Guide the Performance of Venous Resection During Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma with Venous Contact?

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Personalized medicine in pancreatic cancer: the revolution has begun

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Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

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Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials

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Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study

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Association of post-operative CEA with survival and oxaliplatin benefit in patients with stage II colon cancer: a post hoc analysis of the MOSAIC trial

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CDK4/6 Inhibitors in Pancreatobiliary Cancers: Opportunities and Challenges

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Combination, Modulation and Interplay of Modern Radiotherapy with the Tumor Microenvironment and Targeted Therapies in Pancreatic Cancer: Which Candidates to Boost Radiotherapy?

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Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

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