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ArticlesPeer ReviewedFull Text
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Author / Creator:Su, Yichi ; Walker, Joel R. ; Park, Yunhee ; Smith, Thomas P. ; Liu, Lan Xiang ; Hall, Mary P. ; Labanieh, Louai ; Hurst, Robin ; Wang, David C. ; Encell, Lance P. ; Kim, Namdoo ; Zhang, Feijie ; Kay, Mark A. ; Casey, Kerriann M. ; Majzner, Robbie G. ; Cochran, Jennifer R. ; Mackall, Crystal L. ; Kirkland, Thomas A. ; Lin, Michael Z.
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2020-08, Vol.17 (8), p.852-860
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ArticlesPeer ReviewedFull Text
Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs
Author / Creator:Gu, Shuo ; Jin, Lan ; Zhang, Feijie ; Sarnow, Peter ; Kay, Mark A
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2009-02, Vol.16 (2), p.144-150
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The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner
Author / Creator:Gonzalez-Sandoval, Adriana ; Pekrun, Katja ; Tsuji, Shinnosuke ; Zhang, Feijie ; Hung, King L. ; Chang, Howard Y. ; Kay, Mark A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.2448-2448, Article 2448
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A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo
Author / Creator:Chu, Jun ; Oh, Younghee ; Sens, Alex ; Ataie, Niloufar ; Dana, Hod ; Macklin, John J ; Laviv, Tal ; Welf, Erik S ; Dean, Kevin M ; Zhang, Feijie ; Kim, Benjamin B ; Tang, Clement Tran ; Hu, Michelle ; Baird, Michelle A ; Davidson, Michael W ; Kay, Mark A ; Fiolka, Reto ; Yasuda, Ryohei ; Kim, Douglas S ; Ng, Ho-Leung ; Lin, Michael Z
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2016-07, Vol.34 (7), p.760-767
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ArticlesPeer ReviewedFull Text
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
Author / Creator:Valdmanis, Paul N. ; Kim, Hak Kyun ; Chu, Kirk ; Zhang, Feijie ; Xu, Jianpeng ; Munding, Elizabeth M. ; Shen, Jia ; Kay, Mark A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-12, Vol.9 (1), p.5321-9, Article 5321
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The Extragenic Spacer Length Between the 5′ and 3′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors
Author / Creator:Lu, Jiamiao ; Zhang, Feijie ; Xu, Siqun ; Fire, Andrew Z ; Kay, Mark A
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2012-11, Vol.20 (11), p.2111-2119
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Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes
Author / Creator:Gu, Shuo ; Jin, Lan ; Zhang, Feijie ; Huang, Yong ; Grimm, Dirk ; Rossi, John J ; Kay, Mark A
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (22), p.9208-9213
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ArticlesPeer ReviewedFull Text
Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin
Author / Creator:Bleck, Bertram ; Tse, Doris B. ; Curotto de Lafaille, Maria A. ; Zhang, Feijie ; Reibman, Joan
Publisher:Boston: Springer US
Journal title:Journal of clinical immunology, 2008-03, Vol.28 (2), p.147-156
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A transfer-RNA-derived small RNA regulates ribosome biogenesis
Author / Creator:Kim, Hak Kyun ; Fuchs, Gabriele ; Wang, Shengchun ; Wei, Wei ; Zhang, Yue ; Park, Hyesuk ; Roy-Chaudhuri, Biswajoy ; Li, Pan ; Xu, Jianpeng ; Chu, Kirk ; Zhang, Feijie ; Chua, Mei-Sze ; So, Samuel ; Zhang, Qiangfeng Cliff ; Sarnow, Peter ; Kay, Mark A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7683), p.57-62
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ArticlesPeer ReviewedFull Text
A Mini-intronic Plasmid (MIP): A Novel Robust Transgene Expression Vector In Vivo and In Vitro
Author / Creator:Lu, Jiamiao ; Zhang, Feijie ; Kay, Mark A
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2013-05, Vol.21 (5), p.954-963
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ArticlesPeer ReviewedFull Text
Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice
Author / Creator:Tsuji, Shinnosuke ; Stephens, Calvin J. ; Bortolussi, Giulia ; Zhang, Feijie ; Baj, Gabriele ; Jang, Hagoon ; de Alencastro, Gustavo ; Muro, Andrés F. ; Pekrun, Katja ; Kay, Mark A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2022-08, Vol.40 (8), p.1285-1294
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ArticlesPeer ReviewedFull Text
Sequence-Modified Antibiotic Resistance Genes Provide Sustained Plasmid-Mediated Transgene Expression in Mammals
Author / Creator:Lu, Jiamiao ; Zhang, Feijie ; Fire, Andrew Z. ; Kay, Mark A.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-05, Vol.25 (5), p.1187-1198
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ArticlesPeer ReviewedFull Text
289. Sequence Modified Antibiotic Resistance Genes Provide Sustained Plasmid Mediated Transgene Expression in Mammals
Author / Creator:Lu, Jiamiao ; Zhang, Feijie ; Fire, Andrew ; Kay, Mark
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2016-05, Vol.24, p.S116-S116
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ArticlesPeer ReviewedFull Text
RNA interference–induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice
Author / Creator:Valdmanis, Paul N ; Gu, Shuo ; Chu, Kirk ; Jin, Lan ; Zhang, Feijie ; Munding, Elizabeth M ; Zhang, Yue ; Huang, Yong ; Kutay, Huban ; Ghoshal, Kalpana ; Lisowski, Leszek ; Kay, Mark A
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-05, Vol.22 (5), p.557-562
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ArticlesPeer ReviewedFull Text
Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression
Author / Creator:Lisowski, Leszek ; Lau, Ashley ; Wang, Zhongya ; Zhang, Yue ; Zhang, Feijie ; Grompe, Markus ; Kay, Mark A
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2012-10, Vol.20 (10), p.1912-1923
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ArticlesPeer ReviewedFull Text
A tRNA-derived small RNA regulates ribosome biogenesis
Author / Creator:Kim, Hak Kyun ; Fuchs, Gabriele ; Wang, Shengchun ; Wei, Wei ; Zhang, Yue ; Park, Hyesuk ; Roy-Chaudhuri, Biswajoy ; Li, Pan ; Xu, Jianpeng ; Chu, Kirk ; Zhang, Feijie ; Chua, Mei-Sze ; So, Samuel ; Zhang, Qiangfeng Cliff ; Sarnow, Peter ; Kay, Mark A.
Journal title:Nature (London), 2017-11, Vol.552 (7683), p.57-62
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ArticlesPeer ReviewedFull Text
RNAi induced hepatotoxicity results from loss of the first synthesized isoform of miR-122 in mice
Author / Creator:Valdmanis, Paul N. ; Gu, Shuo ; Chu, Kirk ; Jin, Lan ; Zhang, Feijie ; Munding, Elizabeth M. ; Zhang, Yue ; Huang, Yong ; Kutay, Huban ; Ghoshal, Kalpana ; Lisowski, Leszek ; Kay, Mark A.
Journal title:Nature medicine, 2016-04, Vol.22 (5), p.557-562
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737. RNAi Induced Hepatotoxicity Results from a Functional Depletion of the First Synthesized Isoform of miR-122
Author / Creator:Valdmanis, Paul N. ; Gu, Shuo ; Chu, Kirk ; Jin, Lan ; Zhang, Feijie ; Munding, Elizabeth M. ; Zhang, Yue ; Huang, Yong ; Kutay, Huban ; Ghoshal, Kalpana ; Lisowski, Leszek ; Kay, Mark A.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2016-05, Vol.24, p.S290-S291
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ArticlesPeer ReviewedFull Text
Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression
Author / Creator:Lisowski, Leszek ; Lau, Ashley ; Wang, Zhongya ; Zhang, Yue ; Zhang, Feijie ; Grompe, Markus ; Kay, Mark A
Journal title:Molecular therapy, 2012-10, Vol.20 (10), p.1912-1923
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ArticlesPeer ReviewedFull Text
The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs
Author / Creator:Gu, Shuo ; Jin, Lan ; Zhang, Feijie ; Sarnow, Peter ; Kay, Mark A.
Journal title:Nature structural & molecular biology, 2009-02, Vol.16 (2), p.144-150
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Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals

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Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs

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The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner

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A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo

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miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

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The Extragenic Spacer Length Between the 5′ and 3′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors

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Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

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Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin

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A transfer-RNA-derived small RNA regulates ribosome biogenesis

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A Mini-intronic Plasmid (MIP): A Novel Robust Transgene Expression Vector In Vivo and In Vitro

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Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice

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Sequence-Modified Antibiotic Resistance Genes Provide Sustained Plasmid-Mediated Transgene Expression in Mammals

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289. Sequence Modified Antibiotic Resistance Genes Provide Sustained Plasmid Mediated Transgene Expression in Mammals

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RNA interference–induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice

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Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression

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A tRNA-derived small RNA regulates ribosome biogenesis

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RNAi induced hepatotoxicity results from loss of the first synthesized isoform of miR-122 in mice

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737. RNAi Induced Hepatotoxicity Results from a Functional Depletion of the First Synthesized Isoform of miR-122

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Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression

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The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs

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