Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
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Author / Creator
Su, Yichi , Walker, Joel R. , Park, Yunhee , Smith, Thomas P. , Liu, Lan Xiang , Hall, Mary P. , Labanieh, Louai , Hurst, Robin , Wang, David C. , Encell, Lance P. , Kim, Namdoo , Zhang, Feijie , Kay, Mark A. , Casey, Kerriann M. , Majzner, Robbie G. , Cochran, Jennifer R. , Mackall, Crystal L. , Kirkland, Thomas A. and Lin, Michael Z.
Publisher
New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Sensitive detection of two biological events in vivo has long been a goal in bioluminescence imaging. Antares, a fusion of the luciferase NanoLuc to the orange fluorescent protein CyOFP, has emerged as a bright bioluminescent reporter with orthogonal substrate specificity to firefly luciferase (FLuc) and its derivatives such as AkaLuc. However, the...
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Full title
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
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TN_cdi_proquest_miscellaneous_2423799615
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2423799615
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-020-0889-6
